Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(273.482 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.606 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.602 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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Diazoxide-d3
CAS:Produto Controlado<p>Applications Diazoxide-d3 is the labeled analogue of Diazoxide (D417305), which reduces status epilepticus neuron damage in diabetes.<br>References Baba, A., et al.: J. Neurosci., 23, 7737 (2003); Bancila, V., et al.: J. Neurochem., 90, 1243 (2004); Bancila, V., et al.: J. Biol. Chem., 280, 8793 (2005)<br></p>Fórmula:C8H4D3ClN2O2SCor e Forma:NeatPeso molecular:233.691-Naphthol-4-sulfonic Acid Sodium Salt
CAS:Produto Controlado<p>Applications 1-NAPHTHOL-4-SULFONIC ACID SODIUM SALT (cas# 6099-57-6) is a useful research chemical.<br></p>Fórmula:C10H7NaO4SCor e Forma:NeatPeso molecular:246.21Nicergoline-d3
CAS:Produto Controlado<p>Applications Nicergoline-d3 is the labeled analogue of Nicergoline(N394550), a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia.<br>References Caraci, F., et. al.: Brain Res., 1047, 30 (2005); Mizuno, T., et. al.: Brain Res., 1066, 78 (2005)<br></p>Fórmula:C24D3H23BrN3O3Cor e Forma:NeatPeso molecular:487.4046-Hydroxynaphthalene-2-sulfonic Acid Potassium Salt
CAS:<p>Applications 6-Hydroxynaphthalene-2-sulfonic Acid Potassium Salt is used the in the synthesis of azo dyes and pigments.<br>References Gao, Pu. et al., Dyes Pigm. 179, 108376(2020);<br></p>Fórmula:C10H7O4S·KCor e Forma:NeatPeso molecular:262.32358-((4-Amino-3-nitrophenyl)diazenyl)-7-hydroxy-N,N,N-trimethylnaphthalen-2-aminium Chloride (Technical Grade)
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications 8-((4-Amino-2-nitrophenyl)diazenyl)-7-hydroxy-N,N,N-trimethylnaphthalen-2-aminium Chloride is used in the preparation of hair dyes and color intensifiers in cosmetics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Moeller, H., Oberkobusch, D.: Ger. Offen. (2003), DE 10148841 A1 20030410<br></p>Fórmula:C19H20N5O3·ClCor e Forma:NeatPeso molecular:366.39 + 35.45N-Desmethyl Clomipramine Hydrochloride
CAS:Produto Controlado<p>Applications A metabolite of Clomipramine.<br>References McTavish, D., et al.: Drugs, 39, 136 (1990), Chauret, N., et al.: Drug Metab. Dispos., 25, 1130 (1997), Gex-Fabry, M., et al.: Ther. Drug Monit., 22, 701 (2000), Herrera, D., et al.: J. Clin. Pharmacol., 40, 1488 (2000),<br></p>Fórmula:C18H21ClN2·ClHCor e Forma:Off-WhitePeso molecular:337.2922-Hydroxy Mifepristone
CAS:Produto Controlado<p>Applications A metabolite of Mifepristone.<br>References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Fórmula:C29H35NO3Cor e Forma:NeatPeso molecular:445.594-(S)-1-Des(methylamine)-1-oxo-2-(R,S)-hydroxy Sertraline
CAS:Produto ControladoFórmula:C16H12Cl2O2Cor e Forma:NeatPeso molecular:307.17Indole-3-acetic acid Sodium Salt
CAS:Produto Controlado<p>Stability Temperature Sensitive<br>Applications Indole-3-acetic acid is a plant growth regulator. It induces cell division and cell elongation that promotes plant growth.<br>References Fawcett, C., et al.: Nature, 178, 972 (1956); Fawcett, C., et al.: Annals Appl. Bio., 43, 342 (1955); Korshak, V., et al.:Vysokomolekulyarnye Soedineniya, Seriya B: Kratkie Soobshcheniya, 22, 791 (1980)<br></p>Fórmula:C10H8NNaO2Cor e Forma:White To Off-WhitePeso molecular:197.171-Phenyl-1,2,3,4-tetrahydronaphthalene
CAS:<p>Applications 1-phenyl-1,2,3,4-tetrahydronaphthalene (cas# 3018-20-0) is a useful research chemical.<br></p>Fórmula:C16H16Cor e Forma:ColourlessPeso molecular:208.298Imipenem, Monohydrate
CAS:Produto ControladoFórmula:C12H17N3O4S·H2OCor e Forma:White To Light YellowPeso molecular:317.36CRL-40,941
CAS:Produto Controlado<p>Applications CRL-40,941 is a wakefulness-promoting agent. It was found to produce antiaggressive effects in animals.<br>References Lafon, L.: US4489095 (A) (1984)<br></p>Fórmula:C15H13F2NO3SCor e Forma:WhitePeso molecular:325.334-Hydroxy Estrone 1-N7-Guanine
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-Hydroxy Estrone 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Fórmula:C23H25N5O4Cor e Forma:NeatPeso molecular:435.486α-Hydroxy Progesterone (>80%)
CAS:Produto ControladoFórmula:C21H30O3Pureza:>80%Cor e Forma:NeatPeso molecular:330.461,3-Bis(trimethylsilyl)urea
CAS:Produto Controlado<p>Applications 1,3-Bis(trimethylsilyl)urea (cas# 18297-63-7) is a useful research chemical.<br></p>Fórmula:C7H20N2OSi2Pureza:>85%Cor e Forma:NeatPeso molecular:204.42γ-Butyrobetaine-d9
CAS:Produto Controlado<p>Applications γ-Butyrobetaine-d9 is the labelled analogue of γ-Butyrobetaine, a synthetic carnitine related compound used as a transporter substrate in the cloning and sequencing of human carnitine transporter 2 (CT2).<br>References Enomoto, A. et al.: J. Biol. Chem., 277, 36262 (2002)<br></p>Fórmula:C72H9H7NO2Cor e Forma:NeatPeso molecular:155.26Methyl-2-naphthalenemethylamine Hydrochloride
CAS:Produto Controlado<p>Applications An intermediate in the preparation of detoxification inhibitors of the crucifer phytoalexin Brassinin, as potential fungicides against Leptosphaeria maculans.<br>References Gaspari, P., et al.: J. Med. Chem., 49, 684 (2006), Pedras, M., et al.: Bioorg. Med. Chem., 14, 714 (2006),<br></p>Fórmula:C12H14ClNCor e Forma:NeatPeso molecular:207.7Muraglitazar
CAS:Produto Controlado<p>Applications It is a peroxisome proliferator-activated receptor (PPAR) α/γ dual agonist.<br>References Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 6, 427 (2005), Devasthale, P.V., et al.: J. Med. Chem., 48, 2248 (2005), Kendall, D.M., et al.: Diabetes care, 29, 1016 (2006),<br></p>Fórmula:C29H28N2O7Cor e Forma:NeatPeso molecular:516.54(BetaR,DeltaR,1S,2S)-1,2-Dihydro-β,δ,6-trihydroxy-2-methyl-1-naphthaleneheptanoic Acid Sodium Salt (Pravastatin Impurity)
CAS:Produto Controlado<p>Applications Pravastatin impurity.<br>References Muramatsu, S., et al.: Biol. Pharm. Bull., 20, 1199 (1997), Serajuddin, A., et al.: J. Pharm. Sci., 88, 696 (1999),<br></p>Fórmula:C18H23O5·NaCor e Forma:NeatPeso molecular:342.36(S)-(-)-Verapamil-d3 Hydrochloride
CAS:Produto Controlado<p>Applications (S)-(-)-Verapamil-d3 hydrochloride is deuterium labelled S-Verapamil (V124991). Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Peroutka, S., et al.: J. Ann. Neurol, 23, 500 (1988); Eliason, J.F., et al.: Int. J. Cancer, 46, 113 (1990)<br></p>Fórmula:C27H36D3ClN2O4Cor e Forma:NeatPeso molecular:494.08(2-Chloroethyl) Phosphonic Acid-d4
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled (2-Chloroethyl)phosphonic acid. (2-Chloroethyl)phosphonic acid (Ethephon) is the most widely used plant growth regulator. Ethephon is often used on wheat, coffee, tobacco, cotton, and rice in order to help the plant's fruit reach maturity more quickly. The toxicity of Ethephon is actually very low, and any Ethephon used on the plant is converted very quickly to ethylene.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brantley, B., et al.: J. Plant Physiol., 1428, 741 (1960), Ntui, V., et al.: J. Food Agricult. Environ., 5, 211 (2007), Vwioko, E., et al.: Biosci. Res. Communic., 21, 263 (2009),<br></p>Fórmula:C22H4H2ClO3PCor e Forma:NeatPeso molecular:148.523-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid
CAS:Produto Controlado<p>Applications 3-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid (cas# 104582-29-8) is a compound useful in organic synthesis.<br>References Kobayashi, N., et al.: Anal. Biochem., 357, 311 (2006),<br></p>Fórmula:C15H25N3O4S3Cor e Forma:NeatPeso molecular:407.57Bis (2-Ethylhexyl) 4,4’-(6-(4-(ethoxycarbonyl)phenylamino)-1,3,5-triazine-2,4-diyl)bis(azanediyl)dibenzoate
Fórmula:C42H54N6O6Cor e Forma:NeatPeso molecular:738.911α-(Chloromethyl) Chlormadinone Acetate
CAS:Produto Controlado<p>(1α)-17-(Acetyloxy)-6-chloro-1-(chloromethyl)-pregna-4,6-<br>diene-3,20-dione; 6-Chloro-1α-(chloromethyl)-17-<br>hydroxypregna-4,6-diene-3,20-dione Acetate; Cyproterone<br>Acetate EP Impurity C</p>Fórmula:C24H30Cl2O4Cor e Forma:NeatPeso molecular:453.40Bivalirudin α-ASPA 9 Analog Trifluoroacetic Acid Salt (Impurity)
<p>Applications Impurity of Bivalirudin, a direct thrombin inhibitor acting as an anticoagulant through inhibition of the enzyme thrombin.<br>References Bertrand, O. et al.: Am. J. Cardio., 110, 599 (2012); Patti, G. et al.: Am. J. Cardio., 110, 478 (2012);<br></p>Fórmula:C98H137N23O34•xC2HF3O2Cor e Forma:NeatPeso molecular:2181.272-Acetyl-6-(dimethylamino)naphthalene
CAS:Produto Controlado<p>Applications Naphthalene derivative.<br></p>Fórmula:C14H15NOCor e Forma:NeatPeso molecular:213.28O,N-Aminomethanylylidene-β-D-arabinofuranose
CAS:Produto Controlado<p>Applications O,N-Aminomethanylylidene-β-D-arabinofuranose (cas# 27963-98-0) is a compound useful in organic synthesis.<br></p>Fórmula:C6H10N2O4Cor e Forma:NeatPeso molecular:174.15Ethyl Cinnamate
CAS:<p>Applications Ethyl Cinnamate, is used in the preparation of polymer-encapsulated osmonium used as a catalyst for the dihydroxylation of alkenes and preparation of a camptothecin intermediate, anticancer drug. Also used in the synthesis of substrate specific ERK1/2 inhibitors used to induce apoptosis and inhibit cell proliferation.<br>References Akiyama, R. et al.: RSC Adv., 2, 7456 (2012); Li, Q. et al.: Bioorg. Med. Chem. Lett., 19, 6042 (2009);<br></p>Fórmula:C11H12O2Cor e Forma:Colourless To YellowPeso molecular:176.21Oxindole-3-acetic Acid-d4
CAS:Produto ControladoFórmula:C10D4H5NO3Cor e Forma:NeatPeso molecular:195.208N-Acetylthiourea
CAS:Produto Controlado<p>Applications N-Acetylthiourea is a derivative of Thiourea (T375450); a compound used in biochemistry to increase the solubility (and resolution) of membrane proteins in two-dimensional electrophoresis. N-Acetylthiourea can be used as a reducing agent in a two-part self curing endodontic sealing system.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jabbour, S.: Am. J. Clin. Dermatol., 4, 315 (2003); Himsworth, H.: Lancet, 242, 465 (1943); Rabilloud, T., et al.: Electrophoresis, 19, 758 (1998); Jin, S. et al. Self-curing system for endodontic sealant applications. PCT Int. Appl. WO 2009018464 A2 20090205. Feb 5, 2009<br></p>Fórmula:C3H6N2OSCor e Forma:NeatPeso molecular:118.165-Bromoacenaphthene
CAS:Produto Controlado<p>Applications 5-Bromoacenaphthene<br></p>Fórmula:C12H9BrCor e Forma:NeatPeso molecular:233.1Boldenone Propionate
CAS:Produto Controlado<p>Applications Boldenone Propionate is a metabolite of Boldenone (B675100), which is an anabolic steroid.<br>References Watanabe, K., et al.: J. Appl. Bacteriol., 62, 151 (1987) ; Liu, W., et al.: J. Ind. Microbiol., 13, 167 (1994) ; Barthakur, S., et al.: J. Basic Microbiol., 36, 383 (1996); Grinenko, G., et al.: Pharmaceut. Chem. J., 36, 510 (2002) ; de Brabander, H., et al.: Food Addit. Contam., 21, 515 (2004); Le Bizec, B., et al.: Steroids, 71, 1078 (2006);<br></p>Fórmula:C22H30O3Cor e Forma:Off-WhitePeso molecular:342.47Ambrisentan
CAS:Produto Controlado<p>Applications Nonpeptide endothelin ETA receptor antagonist. Antihypertensive.<br>References Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003),<br></p>Fórmula:C22H22N2O4Cor e Forma:Off-WhitePeso molecular:378.42Rosuvastatin tert-Butyl Ester
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin (R700500) a selective, competitive HMG-CoA reductase inhibitor.<br>References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006),<br></p>Fórmula:C26H36FN3O6SCor e Forma:NeatPeso molecular:537.64O-Methyl Atorvastatin Calcium Salt
CAS:Produto Controlado<p>Impurity Atorvastatin EP Impurity G<br>Applications Atorvastatin derivative.<br></p>Fórmula:C34H36FN2O5·CaCor e Forma:Off-WhitePeso molecular:1183.39Des[5-(2-dimethylamino)ethyl] Diltiazem
CAS:Produto Controlado<p>Applications Diltiazem (D460620) intermediate (impurity B).<br>References Chaffman, M., et al.: Drugs, 29, 387 (1985), Kamath, B., et al.: J. Pharm. Biomed. Anal., 11, 407 (1993), Chankvetadze, B., et al.: J. Pharm. Biomed. Anal., 27, 161 (2002),<br></p>Fórmula:C18H17NO4SCor e Forma:NeatPeso molecular:343.40Ethyl Deoxycholate
CAS:<p>Applications Ethyl Deoxycholate is the ethyl ester of the common bile salt Deoxycholic Acid (D232645), a Cholic Acid (C432600) derivative used as a component in cell lysis buffers.<br>References Tuangtong, R. et al.: Dermatol. Surg., 36, 899 (2010); Araki, Y. et al.: Scand. J. Gast., 36, 533 (2001);<br></p>Fórmula:C26H44O4Cor e Forma:White To Off-WhitePeso molecular:420.63N-(n-Butanesulfonyl)-O-[4-(4-pyridinyl)-butyl]-(S)-tyrosine
CAS:<p>Applications Tirofiban intermediate.<br></p>Fórmula:C22H30N2O5SCor e Forma:NeatPeso molecular:434.554-Hydroxy Propofol Sulfate Sodium Salt
CAS:<p>Applications 4-Hydroxy Propofol sulfate sodium salt is a derivative of Propofol, a hypnotic intravenous agent that is commonly used as an anasthetic for conscious sedation.<br>References GüLCIN, I., et al.: Chem. Pharm. Bull., 53, 281 (2005); Koshy, G., et al.: Am. J. Gastroenterol., 95, 1476 (2000)<br></p>Fórmula:C12H17NaO5SCor e Forma:NeatPeso molecular:296.321,2-Dihydro Beclomethasone Dipropionate
CAS:Produto Controlado<p>Impurity Beclomethasone Dipropionate EP Impurity L<br>Applications 1,2-Dihydro Beclomethasone Dipropionate (Beclomethasone Dipropionate EP Impurity L) is an impurity of Beclomethasone Dipropionate (B131030).<br></p>Fórmula:C28H39ClO7Cor e Forma:NeatPeso molecular:523.06Amlodipine Dimethyl Ester
CAS:<p>Impurity Amlodipine EP Impurity F / Amlodipine USP Related Compound F<br>Applications Amlodipine Besilate (A633500) impurity. Amlodipine EP Impurity F<br>References Coburn, R., et al.: J. Med. Chem., 31, 2103 (1988), Gupta, S., et al.: Eur. J. Med. Chem., 38, 867 (2003), Vazzana, I., et al.: J. Med. Chem., 50, 334 (2007),<br></p>Fórmula:C19H23ClN2O5Cor e Forma:Light Yellow To YellowPeso molecular:394.85Dipropofol
CAS:<p>Impurity Propofol EP Impurity E; Propofol USP Related Compound A<br>Applications Dipropofol (Propofol EP Impurity E) is a dimeric derivative of Propofol (P829750). Dipropofol is an antibacterial agent with strong activity againts Gram-positive bacteria. Dipropofol also displays antioxidant and radical scavenging activity. Propofol USP Related Compound A.<br>References Ogata, M. et al.: Chem. Pharm. Bull., 53, 344 (2005); Ogata, M. et al.: Biol. Pharmac. Bull., 30, 1565 (2007);<br></p>Fórmula:C24H34O2Cor e Forma:NeatPeso molecular:354.533-Dehydro Retinal
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications An oxidized derivative of the visual pigment carotenoid.<br>References Wada, A., et al.: Chem. Pharm. Bull., 56, 112 (2008), Smolensky, E., et al.: Biochem., 48, 9170 (2009),<br></p>Fórmula:C20H26OCor e Forma:NeatPeso molecular:282.42Triacetin-d5
CAS:Produto Controlado<p>Applications Triacetin-d5 is the isotope labelled analog of Triacetin (T720850); a compound used as a food additive and flavoring. Triacetin can be used as an excipient in pharmaceutical products where it is used as a humectant, a plasticizer, and as a solvent. Triacetin can also be used as a fuel additive as an antiknock agent.<br>References Mouret, A., et al.: Green Chem., 16 (1), 269 (2014); Snejdrova, E., et al.: Inter. J. Pharma., 458, 282 (2013)<br></p>Fórmula:C9D5H9O6Cor e Forma:NeatPeso molecular:218.252Mycophenolic Acid Phenolic β-D-Glucoside
CAS:Produto ControladoFórmula:C23H30O11Cor e Forma:White To Off-WhitePeso molecular:482.48Melphalan
CAS:Produto Controlado<p>Applications Melphalan is an antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966), Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980),<br></p>Fórmula:C13H18Cl2N2O2Cor e Forma:NeatPeso molecular:305.205-Formyltetrahydropteroic Acid
CAS:Produto Controlado<p>Impurity Calcium Folinate Hydrate EP Impurity E<br>Stability Unstable in Basic Solution<br>Applications 5-Formyltetrahydropteroic Acid is an impurity of Folic Acid (F680300); a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA. It also acts as a cofactor in biological reactions involving folate.<br>References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010); Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010); Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010); McKay, D., et al.: Nut. J., 9 (2010)<br></p>Fórmula:C15H16N6O4Cor e Forma:NeatPeso molecular:344.33
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