
Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(273.463 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.605 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.577 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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5-Bromoacenaphthene
CAS:Produto Controlado<p>Applications 5-Bromoacenaphthene<br></p>Fórmula:C12H9BrCor e Forma:NeatPeso molecular:233.1Diacetyl 2,4-Dinitrophenylhydrazone
CAS:<p>Applications: 2,4-Dinitrophenylhydrazone (DNPH) derivative. Also, it is used in TLC as internal standards.<br>References Lindsay, R.C., et al.: J. Food Sci., 29, 266 (1964),<br></p>Fórmula:C10H10N4O5Cor e Forma:NeatPeso molecular:266.21Ramiprilat(Mixture of Diastereoisomers)
CAS:Produto ControladoFórmula:C21H28N2O5Cor e Forma:NeatPeso molecular:388.46Anastrozole Acid Amide
<p>Applications Anastrozole Acid Amide is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Fórmula:C17H22N4O3Cor e Forma:NeatPeso molecular:330.38N-Nitroso Nipecotic Acid-d4 (Major)
CAS:Produto Controlado<p>Applications A major urinary labelled metabolite of N-nitrosoguvacoline (N527625) and N-nitrosoguvacine, found in cigarette tobacco.<br>References Ernst, H., et al.: Carcinogenesis, 8, 1843 (1987),<br></p>Fórmula:C6H6D4N2O3Cor e Forma:Off-White To BeigePeso molecular:162.181,2-Dihydroxynaphthalene
CAS:Produto Controlado<p>Applications 1,2-Dihydroxynaphthalene 574-00-5 (cas# 574-00-5) is a useful research chemical.<br></p>Fórmula:C10H8O2Cor e Forma:NeatPeso molecular:160.171,8-Dibromoanthracene
CAS:Produto Controlado<p>Applications 1,8-Dibromoanthracene (cas# 131276-24-9) is a useful research chemical.<br></p>Fórmula:C14H8Br2Cor e Forma:NeatPeso molecular:336.02Adenosine-15N
CAS:Produto Controlado<p>Applications Nitrogen 15 labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>Fórmula:C10H1315NN4O4Cor e Forma:NeatPeso molecular:268.235Dihydro Ferulic Acid Methyl Ester
CAS:Produto Controlado<p>Applications A protected caffeine metabolite with high antioxidant activity. It is a very sensitive biomarker for the consumption of relatively small amount of coffee.<br>References Buchanan, C., et al.: J. Sci. Food Agric., 71, 459 (1996), Andreasen, M., et al.: J. Agric. Food Chem., 49, 5679 (2001), Poquet, L., et al.: Drug Metab. Dispos., 36, 190 (2008),<br></p>Fórmula:C11H14O4Cor e Forma:NeatPeso molecular:210.2311b,21-dihydroxypregna-1,4,16-triene-3,20-dione
CAS:<p>Applications 11β,21-dihydroxypregna-1,4,16-triene-3,20-dione is a derivative of Prednisolone (P703740) and an intermediate in the synthesis of isoxazolinopregnadienes which exhibit anti-inflammatory activity.<br>References Khalil, M.A., et al.: Med. Chem. Res., 6, 52 (1996); Kwon, T., et al.: J. Med. Chem., 38, 1048 (1995)<br></p>Fórmula:C21H26O4Cor e Forma:NeatPeso molecular:342.431-Nitronaphthalene
CAS:Produto Controlado<p>Applications 1-Nitronaphthalene as a nitroaromatic compound is studied for mutagenicity, as nitroaromatics are used in everyday products from polmers, dyes to drugs.<br>References Tawari, N., et al.: Int J Pharm Pharm Sci., 6, 149-157 (2014)<br></p>Fórmula:C10H7NO2Cor e Forma:NeatPeso molecular:173.17Ethyl Deoxycholate
CAS:<p>Applications Ethyl Deoxycholate is the ethyl ester of the common bile salt Deoxycholic Acid (D232645), a Cholic Acid (C432600) derivative used as a component in cell lysis buffers.<br>References Tuangtong, R. et al.: Dermatol. Surg., 36, 899 (2010); Araki, Y. et al.: Scand. J. Gast., 36, 533 (2001);<br></p>Fórmula:C26H44O4Cor e Forma:White To Off-WhitePeso molecular:420.631-(2-Nitroethyl)-2-naphthol
CAS:Produto Controlado<p>Applications 1-(2-Nitroethyl)-2-naphthol is an aromatic alcohol that is used in photoacid for extremely long lived and reversible pH jumps.<br>References Nunes, R.M.D., et al.: J. Am. Chem. Soc., 131, 26 (2009);<br></p>Fórmula:C12H11NO3Cor e Forma:NeatPeso molecular:217.224-Hydroxy Propofol Sulfate Sodium Salt
CAS:<p>Applications 4-Hydroxy Propofol sulfate sodium salt is a derivative of Propofol, a hypnotic intravenous agent that is commonly used as an anasthetic for conscious sedation.<br>References GüLCIN, I., et al.: Chem. Pharm. Bull., 53, 281 (2005); Koshy, G., et al.: Am. J. Gastroenterol., 95, 1476 (2000)<br></p>Fórmula:C12H17NaO5SCor e Forma:NeatPeso molecular:296.324-Hydroxy-N-desbutyl Bupivacaine
CAS:Produto Controlado<p>Applications Bupivacaine metabolite.<br>References Goehl, T. J. et al.: Xenobiotica 3, 761 (1973)<br></p>Fórmula:C14H20N2O2Cor e Forma:NeatPeso molecular:248.328-((4-Amino-3-nitrophenyl)diazenyl)-7-hydroxy-N,N,N-trimethylnaphthalen-2-aminium Chloride (Technical Grade)
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications 8-((4-Amino-2-nitrophenyl)diazenyl)-7-hydroxy-N,N,N-trimethylnaphthalen-2-aminium Chloride is used in the preparation of hair dyes and color intensifiers in cosmetics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Moeller, H., Oberkobusch, D.: Ger. Offen. (2003), DE 10148841 A1 20030410<br></p>Fórmula:C19H20N5O3·ClCor e Forma:NeatPeso molecular:366.39 + 35.45L-Methionine Sulfoxide,13C
CAS:Produto Controlado<p>Applications L-Methionine Sulfoxide 13C1 is a labelled analogue of L-Methionine Sulfoxide ( M260450). L-Methionine Sulfoxide ( M260450) an intermediate in the synthesis of the acyclic amino carboxylic acid L-Methionine sulfoximine.<br>References Lee, B., et al.: J. Biol. Chem., 283, 28361 (2008), Nordqvist, A., et al.: Bioorg. Med. Chem., 16, 5501 (2008);Balog, E., et al.: Biochem., 48, 3005 (2009);<br></p>Fórmula:CC4H11NO3SCor e Forma:White To Off-WhitePeso molecular:166.203Indoleacetic Acid-13C6
CAS:Produto Controlado<p>Applications Labelled Indoleacetic Acid (I577343) has the potential to be used in anti-cancer therapy in conjunction with horseradish peroxidase (HRP).<br>References Kawano, T. et al.: Gen. Hypo. 60, 664 (2003);<br></p>Fórmula:C6C4H9NO2Cor e Forma:NeatPeso molecular:181.14Dihydro Caffeic Acid 3-O-Sulfate Sodium Salt
CAS:<p>Stability Hygroscopic<br>Applications A metabolite of Caffeic Acid. Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: identification of biomarkers of coffee consumption.<br>References Buchanan, C., et al.: J. Sci. Food Agric., 71, 459 (1996), Andreasen, M., et al.: J. Agric. Food Chem., 49, 5679 (2001), Poquet, L., et al.: Drug Metab. Dispos., 36, 190 (2008),<br></p>Fórmula:C9H8Na2O7SCor e Forma:NeatPeso molecular:306.20Hederagenin
CAS:<p>Applications Triterpenoid which can inhibit the proliferation of leukemia HL-60 cells.<br>References Cho, J., et al.: Pulmon. Pharmacol. Ther., 23, 190 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Saha, S., et al.: J. Agric. Food Chem., 58, 434 (2010),<br></p>Fórmula:C30H48O4Cor e Forma:NeatPeso molecular:472.70trans Resveratrol 3-O-β-D-glucopyranoside, 98%
CAS:<p>Applications A Stilbenoid glucoside and is a major Resveratrol derivative.<br>References Jeong, E., et al.: Arch. Pharm. Res., 33, 1331 (2010), Larrosa, M., et al.: J. Med. Chem., 53, 7365 (2010), Nguyen, T., et al.: Food Chem., 124, 437 (2010),<br></p>Fórmula:C20H22O8Pureza:98%Cor e Forma:NeatPeso molecular:390.38Methyl Lithocholate
CAS:Produto Controlado<p>Applications Methyl Lithocholate is an derivative of Lithocholic Acid (L469180),a cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones.<br>References Roleira, F.M., et al.: Lett. Drug. Design. Discovery., 7, 610 (2010);<br></p>Fórmula:C25H42O3Cor e Forma:NeatPeso molecular:390.601-Bromonaphthalene-d7
CAS:Produto Controlado<p>Applications 1-Bromonaphthalene-d7 (cas# 37621-57-1) is a compound useful in organic synthesis.<br></p>Fórmula:C102H7BrCor e Forma:ColourlessPeso molecular:214.11Amlodipine Dimethyl Ester
CAS:<p>Impurity Amlodipine EP Impurity F / Amlodipine USP Related Compound F<br>Applications Amlodipine Besilate (A633500) impurity. Amlodipine EP Impurity F<br>References Coburn, R., et al.: J. Med. Chem., 31, 2103 (1988), Gupta, S., et al.: Eur. J. Med. Chem., 38, 867 (2003), Vazzana, I., et al.: J. Med. Chem., 50, 334 (2007),<br></p>Fórmula:C19H23ClN2O5Cor e Forma:Light Yellow To YellowPeso molecular:394.854-(3-Bromo-4-oxobutyl)benzoic Acid Methyl Ester
CAS:Produto Controlado<p>Applications 4-(3-Bromo-4-oxobutyl)benzoic Acid Methyl Ester is used as a reagent in the synthesis of furoxanoxyalkyl esters of pemetrexed as antifolates and nitric oxide donors for use as anticancer agents and their activities against four human cancer cell lines.<br>References Min, T., et al.: Med. Chem. Res., 18, 495 (2009); Barnett, C.J., et al.: Org. Process Res. Dev., 3, 184 (1999)<br></p>Fórmula:C12H13BrO3Cor e Forma:NeatPeso molecular:285.13Docosanoic Acid Methyl Ester
CAS:<p>Applications Docosanoic Acid Methyl Ester is a long chain fatty acid, existing as a wax and is found in sunflower seeds. It can be used in biodiesel production.<br>References Soh, L. et al.: Green Chem., 13, 1422 (2011); Kanya, T.. et al.: Food Chem., 101, 1552 (2006);<br></p>Fórmula:C23H46O2Cor e Forma:Off White SolidPeso molecular:354.61Adenosine 5'-Monophosphomorpholidate 4-Morpholine-N,N'-dicyclohexylcarboxamidine salt
CAS:Produto Controlado<p>Applications Adenosine 5'-Monophosphomorpholidate 4-Morpholine-N,N'-dicyclohexylcarboxamidine salt is an intermediate in the synthesis of Flavine Adenine Dinucleotide.<br>References Ravalico, F., et al.: Org. Biomolec. Chem., 9, 6496 (2011);<br></p>Fórmula:C17H32N3O·C14H20N6O7PCor e Forma:NeatPeso molecular:709.773'-(Trifluoromethyl)acetophenone Oxime
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications m-(Trifluoromethyl)acetophenone Oxime is a reactant in the synthesis of Trifloxystrobin (T778900) which is a broad-spectrum foliar fungicide used in plant protection.<br>References Chen, W., et al.: Huaxue Yanjiu, 25, 16 (2014); Margot, P. et al.: Bright. Crop Prot. Conf. Pest Dis., 2, 375 (1998); Karadimos, D.A. et al.: Crop Prot., 24, 23 (2005); Prom, L.K. et al.: Plant Dis., 87, 252 (2003);<br></p>Fórmula:C9H8F3NOCor e Forma:NeatPeso molecular:203.163,4-Dihydroxyphenylacetic Acid-d5
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 3,4-Dihydroxyphenylacetic Acid-d5 is the labeled analogue of 3,4-Dihydroxyphenylacetic Acid (D454250), a metabolite of Dopamine (D533782).<br>References Johnson, S. et al.: J. Physiol., 450, 455 (1992)<br></p>Fórmula:C8D5H3O4Cor e Forma:Beige To Dark BrownPeso molecular:173.184-Nitropyrene
CAS:Produto Controlado<p>Applications 4-NITROPYRENE (cas# 57835-92-4) is a useful research chemical.<br></p>Fórmula:C16H9NO2Cor e Forma:NeatPeso molecular:247.25(-)-β-Sesquiphellandrene
CAS:Produto Controlado<p>Applications (-)-β-Sesquiphellandrene are found in Tanacetum vulgare plants. It is also an essential leaf and flower oils in Heracleum species.<br>References Clancy, M. V., et al.: Sci. Rep., 6, 38087 (2016); Usjak, L., et al.: Food Funct., 8, 278-290 (2017);<br></p>Fórmula:C15H24Cor e Forma:ColourlessPeso molecular:204.35Acetyltropic Acid
CAS:Produto Controlado<p>Applications Intermediate in the synthesis of Tropine and respective derivatives<br>References Schmidt, G., et al.: J. Pharm. Sci., 56, 215 (1967),<br></p>Fórmula:C11H12O4Cor e Forma:NeatPeso molecular:208.21Hydrocinnamic Acid
CAS:<p>Applications Used in the compositions for the treatment of blood disorders using α-methylhydrocinnamic acid.<br>References Migliaccio, A., et al.: Blood, 76, 1150 (1990), McDonagh, K., et al.: J. Biol. Chem., 266, 11965 (1991),<br></p>Fórmula:C9H10O2Cor e Forma:WhitePeso molecular:150.17DL-Isocitric Acid Lactone
CAS:Produto Controlado<p>Applications DL-Isocitric Acid Lactone (cas# 4702-32-3) was identified as a component in Aloe vera leaves and commercial aloe juice powders.<br>References Zhang, Y., et al.: J. AOAC, 101, 1741 (2018)<br></p>Fórmula:C6H6O6Cor e Forma:NeatPeso molecular:174.11(-)-Terpinen-4-ol
CAS:Produto Controlado<p>Applications (-)-Terpinen-4-ol (cas# 20126-76-5) is a useful research chemical.<br></p>Fórmula:C10H18OCor e Forma:NeatPeso molecular:154.251-Acenaphthenol
CAS:<p>Applications 1-Acenaphthenol is a product of the microbial metabolism and photolysis of acenaphthene, of acenaphthene, a polycyclic hydrocarbon that has potential to act as polyploidizing agents in plants. 1-Acenaphthenol is also a known substrate of dihydrodiol dehydrogenases.<br>References Reyes, C., et al.: J. Photochem. Photobiol. A, 112, 277 (1998); Šavlík, M., et al.: Res. Vet. Sci., 83, 20 (2007); Schocken, M. & Gibson, D.: Appl. Environ. Microb., 48, 10 (1984);<br></p>Fórmula:C12H10OCor e Forma:NeatPeso molecular:170.21Calcium Chloride Hydrate
CAS:<p>Applications Calcium Chloride Dihydrate is used in the preparation of bisphosphonates used in attacking cancer cells.<br>References Liu, D. et al.: Chem. Comm., 48, 2668 (2012);<br></p>Fórmula:Ca·2Cl·2H2OCor e Forma:NeatPeso molecular:147.01Dabigatran Carboxamide Ethyl Ester
CAS:<p>Applications Dabigatran Carboxamide Ethyl Ester is an impurity of Dabigatran Etexilate Mesylate (D100150) which is a nonpeptide, direct thrombin inhibitor.<br>References Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002); Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002); Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005)<br></p>Fórmula:C27H28N6O4Cor e Forma:Off-WhitePeso molecular:500.554’-Benzyloxy-3’-nitroacetophenone
CAS:Produto Controlado<p>Applications 4’-Benzyloxy-3’-nitroacetophenone (cas# 14347-05-8) is a compound useful in organic synthesis.<br></p>Fórmula:C15H13NO4Cor e Forma:NeatPeso molecular:271.27Pteroyltri-γ-L-glutamic acid (>85%)
CAS:<p>Applications Pteroyltri-γ-L-glutamic acid is a folate derivative found in various foods such as yeast, spinach, beef liver, beef fillet and peas.<br>References Tamura, T., et al.: Br. J. Haematol., 25, 513 (1973); Ndaw, S., et al.: J. Chromatogr. A, 928, 77 (2001)<br></p>Fórmula:C29H33N9O12Pureza:>85%Cor e Forma:Off WhitePeso molecular:699.625Urea-urethane Compound (~85%)
CAS:Produto Controlado<p>Applications Urea-urethane Compound is a reaction product of 4,4'-sulfonylbis[benzenamine] and 2,4-TDI.<br></p>Fórmula:C42H36N6O8SPureza:~80%Cor e Forma:NeatPeso molecular:784.84Betamethasone 21-Propionate
CAS:Produto Controlado<p>Impurity Clobetasol Propionate EP Impurity K / Betamethasone Dipropionate EP Impurity C<br>Applications Betamethasone 21-Propionate (Clobetasol Propionate EP Impurity K) is a degradation product of Betamethasone. Glucocorticoid.<br>References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),<br></p>Fórmula:C25H33FO6Cor e Forma:Off-WhitePeso molecular:448.52Dipropofol
CAS:<p>Impurity Propofol EP Impurity E; Propofol USP Related Compound A<br>Applications Dipropofol (Propofol EP Impurity E) is a dimeric derivative of Propofol (P829750). Dipropofol is an antibacterial agent with strong activity againts Gram-positive bacteria. Dipropofol also displays antioxidant and radical scavenging activity. Propofol USP Related Compound A.<br>References Ogata, M. et al.: Chem. Pharm. Bull., 53, 344 (2005); Ogata, M. et al.: Biol. Pharmac. Bull., 30, 1565 (2007);<br></p>Fórmula:C24H34O2Cor e Forma:NeatPeso molecular:354.53Vanillylmethanol
CAS:Produto Controlado<p>Applications An odorant found in strawberries, grapes and olive oil. Vanillylmethanol has high scavenging activities and inhibits homocysteine-induced endothelial cell adhesion.<br>References Ubeda, C. et al.: J. Agr. Food. Chem., 60, 6095 (2012); Barata, A. et al.: J. Agr. Food Chem., 59, 2543 (2011); Manna, C. et al.: J. Agr. Food Chem., 57, 3478 (2009)<br></p>Fórmula:C9H12O3Cor e Forma:NeatPeso molecular:168.19Chlorosulfuric Acid Methyl Ester
CAS:Produto Controlado<p>Stability Moisture Sensitive<br>Applications Chlorosulfuric Acid Methyl Ester is used in the synthesis of acetylenic TACE inhibitors in the treatment of arthritis.<br> E0<br>References Levin, J. et al.: Bioorg. Med. Chem. Lett., 15, 4345 (2005);<br></p>Fórmula:CH3ClO3SCor e Forma:NeatPeso molecular:130.55Mycophenolic Acid Phenolic β-D-Glucoside
CAS:Produto ControladoFórmula:C23H30O11Cor e Forma:White To Off-WhitePeso molecular:482.484-(3’,4’-Dichlorophenyl)-3,4-dihydro-2H-naphthalen-1-one Oxime
CAS:Produto Controlado<p>Applications An intermediate in the synthesis of the drug metabolite for Sertraline.<br></p>Fórmula:C16H13Cl2NOCor e Forma:NeatPeso molecular:306.192-Acetyl-6-(dimethylamino)naphthalene
CAS:Produto Controlado<p>Applications Naphthalene derivative.<br></p>Fórmula:C14H15NOCor e Forma:NeatPeso molecular:213.28Diazolidinyl Urea (Technical Grade)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Diazolidinyl urea is an antimicrobial agent.<br></p>Fórmula:C8H14N4O7Cor e Forma:White To Off-WhitePeso molecular:278.22Phenylglyoxylic Acid-13C8
CAS:<p>Applications Phenylglyoxylic Acid-13C8 is an intermediate used in the synthesis of Mandelic Acid-13C8 (M162523), which is the C13 labelled Mandelic Acid which is used as an antiseptic (urinary). It is also used as a short-term exposure biomarker in urine from styrene exposed workers.<br>References Pessela, B., et al.: Enzyme Microb. Technol., 40, 310 (2007); Carrasco-Lopez, C., et al.: J. Biol. Chem., 284, 4365 (2009); Fustinoni, S., et al.: Toxicol. Lett., 192, 40 (2010)<br></p>Fórmula:C8H6O3Cor e Forma:NeatPeso molecular:158.07

