Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(273.647 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.605 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.602 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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4-(3’,4’-Dichlorophenyl)-3,4-dihydro-2H-naphthalen-1-one Oxime
CAS:Produto Controlado<p>Applications An intermediate in the synthesis of the drug metabolite for Sertraline.<br></p>Fórmula:C16H13Cl2NOCor e Forma:NeatPeso molecular:306.197α-Hydroxy-4-cholesten-3-one
CAS:<p>Applications 7α-Hydroxy-4-cholesten-3-one is a metabolite of Cholesterol (C432501).<br>References Connor, W., et al.: J, Clin. Invest., 48, 1363 (1969), Nestel, P., et al.: Metabolism, 24, 189 (1975), Ellegard, L., et al.: Eur. J. Clin. Nutr., 45, 451 (1991), Pedersen, A., et al.: J. Lipid Res., 41, 1901 (2000),<br></p>Fórmula:C27H44O2Cor e Forma:NeatPeso molecular:400.64Tenofovir Monohydrate
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Tenofovir Monohydrate is an HIV-1 RT inhibitor and antiretroviral drug.<br>References Zhao, Z., et al.: Method for preparing medical salts and/or derivatives of tenofovir disoproxil, and their application for preventing and/or treating HBV and HIV/AIDS infections, CN 101574356 (2009);<br></p>Fórmula:C9H14N5O4P·H2OCor e Forma:NeatPeso molecular:305.23Campesteryl Ferulate
CAS:Produto Controlado<p>Applications Campesteryl Ferulate is a component of γ-oryzanol with antioxidant activities.<br>References Xu, Z., et al.: J. Agric. Food Chem., 49, 2077 (2001);<br></p>Fórmula:C38H56O4Cor e Forma:NeatPeso molecular:576.85Flurandrenolone Acetate
CAS:<p>Impurity Fluocinolone Acetonide EP Impurity G<br>Applications Flurandrenolone Acetate, is the derivative of Flurandrenolide (F598650), which is a Glucocorticoid, used as an antipsoriatic.<br>References Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984), Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),<br></p>Fórmula:C26H35FO7Cor e Forma:NeatPeso molecular:478.55Homogentisic Acid
CAS:<p>Applications An intermediate in the metabolism of tyrosine and phenylalanine. Occurs in plants and in the urine of alkaptonurics.<br>References Knox, W.E., et al.: Biochem. J., 49, 686 (1951), LaDu, B.N., et al.: J. Biol. Chem., 217, 777 (1955)<br></p>Fórmula:C8H8O4Cor e Forma:NeatPeso molecular:168.15(3’S)-ent-Ezetimibe
CAS:<p>Applications An enantiomeric impurity of Ezetimibe (E975005), an antihyperlipoproteinemic and cholesterol absorption inhibitor.<br></p>Fórmula:C24H21F2NO3Cor e Forma:WhitePeso molecular:409.43trans Resveratrol 3-O-β-D-glucopyranoside, 98%
CAS:<p>Applications A Stilbenoid glucoside and is a major Resveratrol derivative.<br>References Jeong, E., et al.: Arch. Pharm. Res., 33, 1331 (2010), Larrosa, M., et al.: J. Med. Chem., 53, 7365 (2010), Nguyen, T., et al.: Food Chem., 124, 437 (2010),<br></p>Fórmula:C20H22O8Pureza:98%Cor e Forma:NeatPeso molecular:390.38Diacetyl Bis(2,4-dinitrophenylhydrazone)
CAS:Produto Controlado<p>Applications 2,4-Dinitrophenylhydrazone (DNPH) derivative.<br>References Lindsay, R.C., et al.: J. Food Sci., 29, 266 (1964),<br></p>Fórmula:C16H14N8O8Cor e Forma:NeatPeso molecular:446.33Xanthurenic Acid
CAS:<p>Applications Excreted by pyridoxine-deficient animals after the ingestion of tryptophan.<br>References Aquilina, J., et al.: Biochemistry, 39, 16176 (2000), Roberts, J., et al.: Photochem. Photobiol., 74, 740 (2001),<br></p>Fórmula:C10H7NO4Cor e Forma:NeatPeso molecular:205.17Hydroflumethiazide
CAS:Produto Controlado<p>Applications Antihypertensive; diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Orzech, C.E., et al.: Anal. Profiles Drug Subs., 7, 297 (1978),<br></p>Fórmula:C8H8F3N3O4S2Cor e Forma:NeatPeso molecular:331.292-Hydroxy Atorvastatin Calcium Salt
CAS:Produto Controlado<p>Applications di(2-Hydroxy Atorvastatin) Calcium Salt is a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Fórmula:C66H68CaF2N4O12Cor e Forma:White To YellowPeso molecular:1187.35(4-Bromophenyl)urea
CAS:<p>Applications (4-Bromophenyl)urea (cas# 1967-25-5) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C7H7N2OBrCor e Forma:Off-White To PurplePeso molecular:215.05trans-Caffeic Acid
CAS:<p>Applications trans-Caffeic Acid is a useful synthetic intermediate. It was used as a reactant to synthesize N-caffeoylphenalkylamide derivatives as bacterial efflux pump inhibitors. It is also used to prepare caffeic acid phenethyl ester analogs with antitumor structures.<br>References Michalet, S., et al.: Bioorg. Med. Chem. Lett., 17, 1755 (2007); Nagaoka, T., et al.: Bioorg. Med. Chem., 10, 3351 (2002)<br></p>Fórmula:C9H8O4Cor e Forma:NeatPeso molecular:180.16Psilocin-d4 (1 mg/mL in Acetonitrile)
CAS:Produto ControladoFórmula:C12D4H12N2OCor e Forma:ColourlessPeso molecular:208.29Diclofenac Carboxylic Acid (Diclofenac Metabolite)
CAS:Produto Controlado<p>Applications Metabolite of Diclofenac.<br>References Duffy, J.C., et al.: J. Pharm. Pharmacol., 48, 883 (1996), Oza, V., et al.: J. Med. Chem., 45, 321 (2002), Bajaj, S., et al.: Bioorg. Med. Chem., 12, 3695 (2004), Teffera, Y., et al.: Drug Metabolism Lett., 2, 35 (2008),<br></p>Fórmula:C13H9Cl2NO2Cor e Forma:Off-WhitePeso molecular:282.12Mianserin N-Oxide
CAS:Produto Controlado<p>Applications A metabolite of Mianserin.<br>References Begg, E., et al.: Br. J. Clin. Pharmacol., 27, 445 (1989), Tybring, G., et al.: Ther. Drug Monit., 17, 516 (1995), Namera, A., et al.: J. Anal. Toxicol. 22, 396 (1998), van Nederkassel, A., et al.: J. Pharm. Biomed. Anal., 32, 233 (2003),<br></p>Fórmula:C18H20N2OCor e Forma:NeatPeso molecular:280.36cis-4-Hydroxycinnamic Acid
CAS:Produto Controlado<p>Applications An antioxidative active compound isolated from the EtOAc layer of MeOH extracts of kochujang, Korean fermented red pepper paste. Photoisomerization of ionic liquid ammonium cinnamates. Cinnamic acids upon irradiation in solution undergo geometric isomerization while dimerizing to different dimers in the crystalline state.<br>References Armstrong, D., et al.: Anal. Chem., 73, 3679 (2001), Karmakar, B., et al.: J. Biotech., 80, 195 (2000),<br></p>Fórmula:C9H8O3Cor e Forma:NeatPeso molecular:164.16Iso Cytosine
CAS:Produto Controlado<p>Applications A useful intermediate for chemical modifications of base and sugar moieties in natural nucleosides.<br>References Sashaki, T., et al.: J. Org. Chem., 40(1), 106 (1975)<br></p>Fórmula:C4H5N3OCor e Forma:NeatPeso molecular:111.107-Hydroxy-1,3,6-naphthalenetrisulfonic Acid Trisodium
CAS:<p>Applications 7-Hydroxy-1,3,6-naphthalenetrisulfonic Acid is a pollutant that is found in waste water.<br>References Cristiano, N., et al.: Ind, Eng. Chem. Res., 46, 6674 (2007)<br></p>Fórmula:C10H5O10S3·3NaCor e Forma:NeatPeso molecular:450.30(-)-β-Copaene
CAS:Produto Controlado<p>Applications (-)-β-Copaene is a natural product, present in very small quantities in numerous plants and trees. It is used in the investigations of acid catalyzed, photochemical and thermally induced rearrangements of Germacrene D (G367765).<br>References Bulow, N., Konig, A.: Phytochemistry, 55, 141 (2000);<br></p>Fórmula:C15H24Cor e Forma:NeatPeso molecular:204.3512,3-Dihydroxy-4-oxopentanoic Acid
CAS:Produto Controlado<p>Applications 2,3-Dihydroxy-4-oxopentanoic Acid is a secondary organic aerosol.<br>References Kleindienst, T., et al.: Atmospheric Environ., 41, 8288 (2007); Stone, E., et al.: Environ. Sci. Tech., 43, 3448 (2009)<br></p>Fórmula:C5H8O5Cor e Forma:NeatPeso molecular:148.11Ezetimibe Tetrahydropyran Impurity
CAS:<p>Impurity Ezetimibe Tetrahydropyran Impurity<br>Applications Ezetimibe (E975000) tetrahydropyran impurity.<br></p>Fórmula:C24H21F2NO3Cor e Forma:NeatPeso molecular:409.434-tert-Butylacetophenone
CAS:Produto Controlado<p>Applications 4-tert-Butylacetophenone is an impurity arising in the synthesis of Ebastine (E320000). Ebastine impurity B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C12H16OCor e Forma:ColourlessPeso molecular:176.252-Carboxybenzoyl Amlodipine
CAS:Produto Controlado<p>Impurity Amlodipine EP Impurity H<br>Applications Amlodipine Besilate (A633500) impurity. Used in the process for preparing Amlodipine benzenesulfonate. Amlodipine EP Impurity H<br></p>Fórmula:C28H29ClN2O8Cor e Forma:NeatPeso molecular:556.992-Fluoroadenosine
CAS:Produto Controlado<p>Applications 2-Fluoroadenosine is a fluorinated analog of Adenoside (A280400) nucleotide.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010);<br></p>Fórmula:C10H12FN5O4Cor e Forma:NeatPeso molecular:285.23Theobromine-d6
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A labelled metabolite of Caffeine.<br>References Suto, M., et al.: Anticancer Drug Des., 6, 107 (1991), Burkart, V., et al.: Nat. Med., 5, 314 (1999), Hassa, P., et al.: J. Biol. Chem., 278, 45145 2003), Veres, B., et al.: J. Pharmacol. Exp. Ther., 310, 247(2004),<br></p>Fórmula:C72H6H2N4O2Cor e Forma:WhitePeso molecular:186.202-Methylnaphthalene-D10
CAS:Produto Controlado<p>Applications 2-Methylnaphthalene-D10 is a labelled analogue of 2-Methylnaphthalene (M323130). 2-Methylnaphthalene is a polycyclic aromatic hydrocarbon (PAH) that has been used as an indicator of smoke exposure in food and packaging materials.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Johnston, J.J., et. al.: J. Agr. Food Chem., 42, 1954 (1994)<br></p>Fórmula:C112H10Cor e Forma:NeatPeso molecular:152.262-Naphthol
CAS:<p>Applications: Has been used as antiseptic, anthelmintic and counter-irritant in alopecia.<br>Dangerous Goods Info: Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Diggle, S., et al.: Chem. Biol., 13, 701 (2006), Tashiro, Y., et al.: J. Bacteriol.,190, 3969 (2008),<br></p>Fórmula:C10H8OCor e Forma:NeatPeso molecular:144.17β-Benzyl L-Aspartic Acid N-carboxyanhydride
CAS:Produto Controlado<p>Applications β-Benzyl L-Aspartic Acid N-carboxyanhydride is used in the synthesis of PEG-poly(aspartate) block copolymer micelles in cancer cells.<br>References Eckman, A., et al.: Pharm. Res, 29, 1755 (2012); Guo, M., et al.: Biomateials, 35, 4656 (2014)<br></p>Fórmula:C12H11NO5Cor e Forma:NeatPeso molecular:249.22Diltiazem-d3 Hydrochloride
CAS:Produto Controlado<p>Applications Labelled Diltiazem (D460620). A calcium channel blocher with vasodilating activity. Antianginal; antihypertensive; antiarrhythmic (class IV).<br>References Sato, et al.: Arzneim.-Forsch., 21, 1338 (1971), Smirnov, S.R.: Eur. J. Pharmacol., 360, 81 (1998), Hansson, L., et al.: Lancet, 356, 359 (2000),<br></p>Fórmula:C22H24D3ClN2O4SCor e Forma:NeatPeso molecular:454.0O-Methyl Atorvastatin Calcium Salt
CAS:Produto Controlado<p>Impurity Atorvastatin EP Impurity G<br>Applications Atorvastatin derivative.<br></p>Fórmula:C34H36FN2O5·CaCor e Forma:Off-WhitePeso molecular:1183.39Rosuvastatin tert-Butyl Ester
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin (R700500) a selective, competitive HMG-CoA reductase inhibitor.<br>References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006),<br></p>Fórmula:C26H36FN3O6SCor e Forma:NeatPeso molecular:537.641-Naphthol
CAS:<p>Impurity Duloxetine EP Impurity D<br>Applications 1-Naphthol (Duloxetine EP Impurity D) is used in the manufacturing of dyes, intermediates, synthetic perfumes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C10H8OCor e Forma:Light Red To Light BrownPeso molecular:144.178-anti-Ipratropium Bromide
CAS:Produto Controlado<p>Impurity Ipratropium EP Impurity B<br>Applications 8-anti-Ipratropium Bromide (Ipratropium EP Impurity B) is a related compound to Ipratropium Bromide (I740500), nonselective muscarinic acetylcholine receptor antagonist; bronchodilator.<br>References Groeben, H., et al.: Anesthesiology, 85, 867 (1996), Haddad, et al.: Br. J. Pharmacol., 127, 413 (1999), Barnes, P. J., et al.: Chest, 117, 63S (2000),<br></p>Fórmula:C20H30NO3·BrCor e Forma:NeatPeso molecular:412.36(R)-(-)-Carvone 4,4,6,6-d4
CAS:Produto Controlado<p>Applications (R)-(-)-Carvone-d4 is an intermediate in synthesizing (+)-Limonene-d5 (L461742). It is present in blood oranges which show inhibition of angiogenesis in human colon cancer cells. Extracted from the oils of Mentha spicata it shows antimicrobial activity.<br>References Chidambara Murthy, K. et al.: Life Sci.,91, 429 (2012); Aggarwal, K. et al.: Flav. Frag. J., 17, 59 (2002)<br></p>Fórmula:C10D4H10OCor e Forma:NeatPeso molecular:154.242Atorvastatin Acetonide
CAS:<p>Applications Protected Atorvastatin.<br></p>Fórmula:C36H39FN2O5Cor e Forma:Off-White To Light YellowPeso molecular:598.70Atorvastatin Lactam Sodium Salt Impurity
CAS:<p>Impurity Atorvastatin Pyrrolidone Analog (USP)<br>Stability Light Sensitive<br>Applications A photodegradation product of Atorvastatin (a cyclic impurity of Atorvastatin). Atorvastatin Pyrrolidone Analog (USP).<br>References Roger, D., et al.: Clin. Exp. Dermatol., 19, 88 (1994), Cosa, G., et al.: Photochem. Photobiol., 80, 159 (2004), Kerwin, B., et al.: J. Pharm. Sci., 96, 1468 (2007),<br></p>Fórmula:C33H34FN2O6·NaCor e Forma:WhitePeso molecular:596.62rac 1-Methoxy Ketorolac
CAS:Produto Controlado<p>Applications An impurity of the analgesic Ketorolac (K235650).<br></p>Fórmula:C16H15NO4Cor e Forma:NeatPeso molecular:285.291, N2-Etheno-2'-deoxyguanosine-13C5
CAS:Produto Controlado<p>Applications 1, N2-Etheno-2’-deoxyguanosine-13C5 is caused by exposure to pollutants. It is an isotopically labeled analog of the 2’-Deoxyguanosine adduct.<br></p>Fórmula:C713C5H13N5O4Cor e Forma:NeatPeso molecular:296.23Kinetin Riboside
CAS:Produto Controlado<p>Applications Used as an anticancer and antiviral agent.<br>References Cancer Res., 20, 1362 (1960), Virology, 38, 26 (1969),<br></p>Fórmula:C15H17N5O5Cor e Forma:NeatPeso molecular:347.33Diazoxide-d3
CAS:Produto Controlado<p>Applications Diazoxide-d3 is the labeled analogue of Diazoxide (D417305), which reduces status epilepticus neuron damage in diabetes.<br>References Baba, A., et al.: J. Neurosci., 23, 7737 (2003); Bancila, V., et al.: J. Neurochem., 90, 1243 (2004); Bancila, V., et al.: J. Biol. Chem., 280, 8793 (2005)<br></p>Fórmula:C8H4D3ClN2O2SCor e Forma:NeatPeso molecular:233.699α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one
CAS:<p>Impurity Clobetasol Propionate EP Impurity J<br>Applications 9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one (Clobetasol Propionate EP Impurity J) is an impurity in the synthesis of Clobetasol 17-Propionate (C583500), a topical corticosteroid. Glucocorticoid; anti-inflammatory.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),<br></p>Fórmula:C25H30ClFO4Cor e Forma:NeatPeso molecular:448.95Camphorquinone-10-sulfonic Acid Hydrate
CAS:Produto Controlado<p>Applications A crystalline water-soluble reagent that is useful for specific, reversible modification of the guanidino groups of arginine residues. Suitable for use with small arginine-containing molecules.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wallace, C.J.A., et al.: Biochem. J., 215, 651 (1983), Dailey, H.A., et al.: J. Biol. Chem., 261, 7902 (1986),<br></p>Fórmula:C10H14O5S·H2OCor e Forma:NeatPeso molecular:264.30S 23
CAS:<p>Applications S 23 is a selective androgen receptor modulator.<br>References Thevis, M., et al.: Drug Testing and Analysis, 2, 589 (2010); Jones, A., et al.; Endocr., 150, 385 (2009)<br></p>Fórmula:C18H13ClF4N2O3Cor e Forma:White To Off-WhitePeso molecular:416.759-Nitroanthracene-d9
CAS:Produto Controlado<p>Applications 9-Nitroanthracene-d9 (CAS# 220381-38-4) is a useful isotopically labelled research compound. It could be useful for analytical studies that involve detecting nitrated polycyclic aromatic hydrocarbons.<br>References Siegmund, B., et al.: Anal. Bioanal. Chem., 375, 175 (2003)<br></p>Fórmula:C14D9NO2Cor e Forma:NeatPeso molecular:232.29Chenodeoxycholic acid-3-β-D-glucuronide
CAS:Produto ControladoFórmula:C30H48O10Cor e Forma:White To Off-WhitePeso molecular:568.7Desacetyl Diltiazem
CAS:<p>Impurity Diltiazem EP Impurity F<br>Applications Desacetyl Diltiazem (Diltiazem EP Impurity F) is a metabolite of Diltiazem (D460620).<br>References Shallcross, H., et al.: Br. Med. J., 295, 1236 (1987), Yeung, P.K.F., et al.: Drug Metab. Dispos., 18, 1055 (1990), Cashman, J.R., et al.: J. Med. Chem., 34,2049 (1991),<br></p>Fórmula:C20H24N2O3SCor e Forma:White To BrownPeso molecular:372.48Epitizide
CAS:Produto Controlado<p>Applications Epitizide is a diuretic agent.<br>References Pilsbury, V., et al.: J. Pharm. Pharmacol., 18, 713 (1966), Tisdall, P., et al.: Clin. Chem., 26, 702 (1980),<br></p>Fórmula:C10H11ClF3N3O4S3Cor e Forma:White To Off-WhitePeso molecular:425.86Desacetyl Rifampicin Quinone
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Desacetyl Rifampicin Quinone is an impurity of Rifampicin (R508000).<br>References Wilson, W.L. et al.: J. Chrom., 144, 270 (1977);<br></p>Fórmula:C41H54N4O11Cor e Forma:NeatPeso molecular:778.89Pranoprofen
CAS:Produto Controlado<p>Applications Pranoprofen is an anti-inflammatory used in ophthalmology.<br>References Ayaki, M., et al.: Biocont. Sci., 15, 97 (2010); Lee, X., et al.: For. Toxicol., 28, 96 (2010);<br></p>Fórmula:C15H13NO3Cor e Forma:Off White CrystallinePeso molecular:255.27Bromfenac Sodium Sesquihydrate
CAS:Produto Controlado<p>Applications Bromfenac is a non-steroidal anti-inflammatory agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Obach, R., et al.: Drug Metab. Disposition, 36, 1385 (2008), MacDonald, J., et al.: Toxicol. Sci., 110, 40 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),<br></p>Fórmula:C15H11BrNO3·2Na·3H2OCor e Forma:Light YellowPeso molecular:766.347-Nitrocoumarin
CAS:Produto Controlado<p>Applications Coumarin derivatives were made for trial as bacteriostats.<br></p>Fórmula:C9H5NO4Cor e Forma:NeatPeso molecular:191.142,3,4-Trihydroxybenzophenone-2’,3’,4’,5’,6’-d5
CAS:Produto Controlado<p>Applications 2,3,4-Trihydroxybenzophenone-2’,3’,4’,5’,6’-d5 is the isotope labelled analog of 2,3,4-Trihydroxybenzophenone; a trihydroxy derivative of Benzophenone (B204980) which is a compound used in the manufacturing of antihistamines, hypnotics, and insecticides.<br>References Wallace, W., et al.: Environ. Toxicol. Chem., 19, 962 (2000); Hayashi, T., et al.: Toxicol. Lett., 167, 1 (2006); Bechard, K., et al.: Aquat. Toxicol., 90, 310 (2008)<br></p>Fórmula:C13D5H5O4Cor e Forma:NeatPeso molecular:235.2474-Bromobenzoic Acid Methyl Ester
CAS:<p>Applications 4-Bromobenzoic Acid Methyl Ester is halogenated benzoate used as a reagent in organic synthesis. 4-Bromobenzoic Acid Methyl Ester can be used to stimulate microbial dechlorination of PCBs. 4-Bromobenzoic Acid Methyl Ester is also used in the preparation of stable radioiodinating reagent to label monoclonal antibodies for radiotherapy of cancer.<br>References Wilbur, D.S. et al.: J. Nuclear Med., 30, 216 (1989); DeWeerd, K.A. et al.: Environ. Sci. Technol., 33, 2057 (1999);<br></p>Fórmula:C8H7BrO2Cor e Forma:Off-WhitePeso molecular:215.04Selenosulfuric Acid Dipotassium Salt, Technical Grade
CAS:Produto Controlado<p>Applications Selenosulfuric Acid Disodium Salt is used in the synthesis of CdSe photocatalysts with enhanced photocatalytic ativitys. Possible application towards industrial wastewater treatment and pollutant removal.<br>References Lim, C. et al.: Bull. Korean Chem Soc., 32, 1657 (2011);<br></p>Fórmula:K2O3SSeCor e Forma:NeatPeso molecular:237.22N-Formyl Varenicline
CAS:Produto Controlado<p>Applications A metabolite of Varenicline. Metabolite M5.<br>References Dow, J., et al.: Drug Metab. Dispos., 22, 738 (1994), Toide, K., et al.: Biochem. Pharmacol., 67, 1269 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Doll, R., et al.: Br. J. Cancer, 92, 426 (2005),<br></p>Fórmula:C14H13N3OCor e Forma:NeatPeso molecular:239.271,5-Dinitronaphthalene
CAS:Produto Controlado<p>Applications 1,5-DINITRONAPHTHALENE (cas# 605-71-0) is a useful research chemical.<br></p>Fórmula:C10H6N2O4Cor e Forma:NeatPeso molecular:218.17Limonin
CAS:<p>Applications Limonin is a limonoid extracted from various citrus plants. Bioactivity of Limonin have been revolved around its anti-HIV properties.<br>References Battinelli, L., et al.: Planta. Med., 69, 910 (2003); Kim, J., et al.: Food. Function., 4, 258 (2013); Chaudhary, P., et al.: Food. Chem., 135, 1667 (2012);<br></p>Fórmula:C26H30O8Cor e Forma:NeatPeso molecular:470.51Sodium Azide
CAS:<p>Applications Sodium azide is commonly used as a preservative in aqueous laboratory reagents and biological samples. Sodium azide’s toxicity can be attributed to its role as a reversible inhibitor of mitochondrial respiration and insulin secretion in human pancreatic cells. Acts as a catalyst for: Oxidative decarboxylation & Michael addition reactions.Used as a reagent for synthesis of Blue fluorescent copolymers; Metal phosphonates & Arenes via aminations. Actively involved in regioselective synthesis of prianosin B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chang, S. & Lamm, S.: Int. J. Toxicol., 22, 175 (2003); Misler, S., et al.: Pflügers Archiv., 421, 289 (1992)<br></p>Fórmula:N3·NaCor e Forma:White To Off-WhitePeso molecular:65.01cis-β-Hydroxy Tamoxifen
CAS:Produto Controlado<p>Applications A hydroxylated analogue of Tamoxifen (T006000) with anti-estrogenic properties.<br>References Ruenitz, P.C. et al.: J. Med. Chem., 25, 1056 (1982)<br></p>Fórmula:C26H29NO2Cor e Forma:NeatPeso molecular:387.51Adenosine-5',5''-d2
CAS:Produto Controlado<p>Applications Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>Fórmula:C10H11D2N5O4Cor e Forma:White SolidPeso molecular:269.26Isovaleryl L-Carnitine-d3 Chloride
CAS:Produto Controlado<p>Applications Isovaleryl L-Carnitine-d3 Chloride is labelled Isovaleryl L-Carnitine Chloride (I917580) which is used to prepare carnitine benzyl esters as neuroprotectant prodrugs.<br>References Gong, X., et al.: J. Chem. Res., 6, 327 (2008)<br></p>Fórmula:C12D3H21NO4·ClCor e Forma:NeatPeso molecular:284.7952',4-Bis(aminophenyl)methane
CAS:Produto Controlado<p>Applications 2',4-Bis(aminophenyl)methane is an analog of 4,4'-Methylenedianiline (M304180) and is used in the manufacturing of resin enamel coating materials for copper wires.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bhanu, V.A., et al.: Paintindia, 59, 77 (2009)<br></p>Fórmula:C13H14N2Cor e Forma:Off-WhitePeso molecular:198.26Valeric Acid-d9
CAS:Produto Controlado<p>Applications Valeric Acid-d9 is the isotope labelled analog of Valeric Acid which is used in biological studies of (D)-β-hydroxybutyrate which inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Taggart, A.K.P., et al.: J. Bio. Chem., 280, 26649 (2005);<br></p>Fórmula:C5D9HO2Cor e Forma:NeatPeso molecular:111.19Triacetin-d9
CAS:Produto Controlado<p>Applications Triacetin-d5 is the isotope labelled analog of Triacetin (T720850); a compound used as a food additive and flavoring. Triacetin can be used as an excipient in pharmaceutical products where it is used as a humectant, a plasticizer, and as a solvent. Triacetin can also be used as a fuel additive as an antiknock agent.<br>References Mouret, A., et al.: Green Chem., 16 (1), 269 (2014); Snejdrova, E., et al.: Inter. J. Pharma., 458, 282 (2013)<br></p>Fórmula:C9D9H5O6Cor e Forma:NeatPeso molecular:227.263-Sulfoglycolithocholic Acid Disodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 3-Sulfoglycolithocholic Acid Disodium Salt is a derivative of Lithocholic acid (L469180). Lithocholic acid (LCA) is a putative tumor promoter,that is shown to be able to inhibit mammalian DNA polymerase β.<br>References Ogawa, A., et al.: Jap. J. Canc. Res., 89, 1154 (1998)<br></p>Fórmula:C26H41NO7S·2NaCor e Forma:NeatPeso molecular:557.653'-Azido-3'-deoxythymidine-methyl-d3 β-D-glucuronide, Sodium Salt
CAS:Produto Controlado<p>Applications A deuterated metabolite of the potent and selective inhibitor of HIV-1 replication, AZT.This compounds contains Sodium Chloride. Water content not determined.<br></p>Fórmula:C16D3H17N5O10·NaCor e Forma:NeatPeso molecular:468.36584,4’-Bis(4”-aminobenzenesulfonyl) Diphenyl Ether Dihydrochloride
CAS:<p>Applications The diamino arylene disulfones used in polyamido polysulfone thermoplastics and intermediates.<br></p>Fórmula:C24H20N2O5S2•2HClCor e Forma:NeatPeso molecular:553.47Pteroyltri-γ-L-glutamic acid (>85%)
CAS:<p>Applications Pteroyltri-γ-L-glutamic acid is a folate derivative found in various foods such as yeast, spinach, beef liver, beef fillet and peas.<br>References Tamura, T., et al.: Br. J. Haematol., 25, 513 (1973); Ndaw, S., et al.: J. Chromatogr. A, 928, 77 (2001)<br></p>Fórmula:C29H33N9O12Pureza:>85%Cor e Forma:Off WhitePeso molecular:699.625Fluorescein-Cadaverine Dihydrochloride
CAS:<p>Stability Hygroscopic<br>Applications Fluorescein-Cadaverine is a fluorescein derivative used in the preparation of biologically active fluorescent-labeled vitamin K analogues and monitoring of their subcellular distribution.<br>References Suhara, Y. et al.: Tetrahedron, 64, 8789 (2008);<br></p>Fórmula:C26H25N3O5S·2ClHCor e Forma:Orange SolidPeso molecular:564.483,5-Bis(1,1-dimethylethyl)-4-hydroxy-benzenepropanoic Acid C7-9-Branched Alkyl Esters
CAS:<p>Applications Octyl-3,5-di-tert-butyl-4-hydroxyhydrocinnamate (cas# 125643-61-0) is an intermediate in synthesizing 7,9-Di-tert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione (D493755), an antioxidant naturally found in aerial parts of Gmelina asiatica Linn (Verbenaceae). It is also found in essential oils of some Stachys species from Mediterranean area. It is an impurity of Irganox used in the food packaging.<br>References Merlin, N., et al.: Pharmacogn. Res., 1, 152 (2009); Conforti, F., et al.: Food Chem., 116, 898 (2009), Riquet, A. et al.: Food Chem., 199, 59 (2016);<br></p>Fórmula:C25H42O3Cor e Forma:ColourlessPeso molecular:390.61N-Acetyl-2-naphthylamine
CAS:Produto Controlado<p>Applications N-Acetyl-2-naphthylamine was used in the preparation of novel phenyl pyrazolone-substituted 1H-benzo[g]pyrazolo[3,4-b]quinoline-3-ylamine derivatives that exhibits antituberculosis and antibacterial activities.<br>References Parekh, N.M., et al.: Res. Chem. Inter. 30, 885 (2012); Parekh, N.M., et al.: Med. Chem., Res., 21, 4168 (2012);<br></p>Fórmula:C12H11NOCor e Forma:NeatPeso molecular:185.22Biotin Sulfone
CAS:Produto Controlado<p>Applications Biotin Sulfone, is derivative of Biotin (B389040), which is a growth factor present in minute amounts in every living cell, and plays an indispensable role in numerous naturally occurring carboxylation reactions.<br>References du Vigneaud, et al.: J. Biol. Chem., 146, 475 (1942), Traub, et al.: Nature, 178, 649 (1956), Siegel, H., et al.: Experienta, 37, 789 (1981), Vesely, D.L., Science, 216, 1329 (1982), Hugues, M., et al.: Biochemistry, 31, 12 (1992),<br></p>Fórmula:C10H16N2O5SCor e Forma:NeatPeso molecular:276.31(S)-Ramelteon Metabolite M-II
CAS:Produto Controlado<p>Applications S-Ramelteon Metabolite M-II is a metabolite of Ramelteon in serum (M-II).<br>References Karim, A., et al.: J. Clin. Pharmacol., 44, 1210 (2004); Prescott, E., et al.: Drug Metab. Rev., 36, 203 (2004); Kato, K., et al.: Neuropharmacology, 48, 301 (2005); Karim, A., et al.: J. Clin. Pharmacol., 46, 140 (2006)<br></p>Fórmula:C16H21NO3Cor e Forma:NeatPeso molecular:275.34Citric acid-2,4-13C2
CAS:Produto Controlado<p>Applications Citric acid-2,4-13C2 is an isotopic analog of citric acid (C521000), a component of the Krebs cycle.<br></p>Fórmula:C2C4H8O7Cor e Forma:White To Light YellowPeso molecular:194.114-Nitro-4’-aminodiphenyl Sulfone
CAS:<p>Applications An intermediate in the synthesis of the Daspone metabolite.<br></p>Fórmula:C12H10N2O4SCor e Forma:NeatPeso molecular:278.281-Nitropiperazine-d8
CAS:Produto Controlado<p>Applications Labelled nitro substituted piperazine.<br></p>Fórmula:C4HD8N3O2Cor e Forma:NeatPeso molecular:139.18Hydrocinnamic Acid
CAS:<p>Applications Used in the compositions for the treatment of blood disorders using α-methylhydrocinnamic acid.<br>References Migliaccio, A., et al.: Blood, 76, 1150 (1990), McDonagh, K., et al.: J. Biol. Chem., 266, 11965 (1991),<br></p>Fórmula:C9H10O2Cor e Forma:WhitePeso molecular:150.173',4',7,8-Tetrahydroxyflavone
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications 3',4',7,8-Tetrahydroxyflavone (cas# 3440-24-2) is a useful research chemical.<br></p>Fórmula:C15H10O6Cor e Forma:Light YellowPeso molecular:286.24N-Des(4-Fluorophenyl)-N-(3-fluorophenyl) Ezetimibe
CAS:Fórmula:C24H21F2NO3Cor e Forma:Off White SolidPeso molecular:409.43Rosuvastatin Triphenylphosphonium Bromide
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications An intermediate in the production of Rosuvastatin (R700500) derivatives.<br></p>Fórmula:C34H34FN3O2PS·BrCor e Forma:WhitePeso molecular:678.596β-Hydroxy-21-desacetyl Deflazacort
CAS:<p>Applications The major metabolite of Deflazacort.<br>References Bernareggi, A., et al.: J. Pharma. Biomed. Anal., 5, 177-81 (1987), Assandri, A., et al.: Xenobiotica, 13(3), 185 (1983), Martinelli, E., et al.: Drug Metab. Dispos., 7, 335 (1979),<br></p>Fórmula:C23H29NO6Cor e Forma:NeatPeso molecular:415.48Digoxigenin Monodigitoxoside
CAS:Produto Controlado<p>Applications A metabolite of Digoxin (Dx) (D446575).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujii, Y., et al.: Clin. Chem., 37, 476 (1991), Salphati, L., et al.: Xenobiotica, 29, 171 (1999), Song, S., et al.: Drug Metab. Dispos., 27, 689 (1999),<br></p>Fórmula:C29H44O8Cor e Forma:BeigePeso molecular:520.653-(4-Chlorophenyl)-4-hydroxybutyric Acid Sodium Salt
CAS:Produto Controlado<p>Applications A metabolite of Baclofen (c).<br>References Ault, B., et al.: Eur. J. Pharmacol., 71, 357 (1981),<br></p>Fórmula:C10H10ClNaO3Cor e Forma:NeatPeso molecular:236.63Benzoic Acid
CAS:Produto Controlado<p>Impurity Mefenamic Acid EP Impurity D<br>Applications Benzoic Acid is used in the synthesis of 1,3,4-oxadiazoles with pharmaceutical activity. Also used in the synthesis of selective human A3 adenosine receptor antagonists.<br>References Rouhani, M. et al.: Ultrason. Biochem., 21, 262 (2014); Squarcialupi, L. et al.: J. Medic. Chem., 56, 2256 (2013);<br></p>Fórmula:C7H6O2Cor e Forma:WhitePeso molecular:122.12rac 3,4-Dihydroxymandelic Acid-d3
CAS:Produto Controlado<p>Applications A labelled protein kinase C inhibitor.<br>References Marki, H.P., et al.: Helv. Chimica Acta, 71, 320 (1988), Iwagami, H., et al.: Bull. chem. Soc. Jpn., 63, 3073 (1990), Funahashi, T., et al.: J. Bacteriol., 184, 936 (2002),<br></p>Fórmula:C8H5D3O5Cor e Forma:NeatPeso molecular:187.169-(N-Methylaminomethyl)anthracene
CAS:Produto Controlado<p>Applications 9-(N-Methylaminomethyl)anthracene is a reactant that has been used in the synthesis of anthracene-oxyquinoline dyad as a fluorescent indicator for Hg(II).<br>References Praveen, L., et. al.: Tetrahedron Lett., 53, 3951 (2012)<br></p>Fórmula:C16H15NCor e Forma:NeatPeso molecular:221.3Vitamin K1 Hydroxide
CAS:Produto Controlado<p>Stability Temperature and Light Sensitive, unstable in solution<br>Applications Vitamin K1 Hydroxide is a derivative of Vitamin K1 (V676080), which occurs widely in green plants, algae, and photosynthetic bacteria.<br>References Hassan, M.M.A., et al.: Anal. Profiles Drug Subs., 17, 449 (1988), Breton, J., et al.: Biochemistry, 33, 12405 (1994), Dowd, P., et al.: Science, 269, 1684 (1995),<br></p>Fórmula:C31H46O3Cor e Forma:NeatPeso molecular:466.7Hydroxydehydro Nifedipine Carboxylate
CAS:Produto ControladoFórmula:C16H14N2O7Cor e Forma:NeatPeso molecular:346.29Caffeidine Acid Sodium Salt
CAS:Produto Controlado<p>Applications Caffeidine Acid is a potential degradation product from the hydrolysis of Caffeine (C080100) under alkaline environment.<br>References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988);<br></p>Fórmula:C8H11N4O3·NaCor e Forma:NeatPeso molecular:234.19(S)-(+)-Ibuprofen-d3
CAS:Produto Controlado<p>Applications A labelled nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Fórmula:C13H15D3O2Cor e Forma:NeatPeso molecular:209.3Indoleacetic Acid-d4
CAS:Produto Controlado<p>Applications Labelled Indoleacetic Acid (I577343) has the potential to be used in anti-cancer therapy in conjunction with horseradish peroxidase (HRP).<br>References Kawano, T. et al.: Gen. Hypo. 60, 664 (2003);<br></p>Fórmula:C102H4H5NO2Cor e Forma:NeatPeso molecular:179.216α-Bromo Beclomethasone Dipropionate
CAS:Produto Controlado<p>Impurity Beclomethasone Dipropionate EP Impurity F<br>Applications 6α-Bromo Beclomethasone Dipropionate (Beclomethasone Dipropionate EP Impurity F) is an impurity of Beclomethasone Dipropionate (B131030).<br></p>Fórmula:C28H36BrClO7Cor e Forma:White SolidPeso molecular:599.947-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin
CAS:Produto Controlado<p>Applications A major metabolite of Irinotecan.<br>References Canal, P., et al.: J. Clin. Oncol., 14, 2688 (1996), Haaz, M., et al.: Cancer Res., 58, 468 (1998), Kehrer, D., et al.: Clin. Cancer Res., 6, 3451 (2000), Hanioka, N., et al.: Xenobiotica, 31, 687 (2001), Satoh, T., et al.: Drug Metab. Dispos., 30, 488 (2002),<br></p>Fórmula:C33H38N4O8Cor e Forma:Light YellowPeso molecular:618.67686β-Hydroxy Betamethasone
CAS:Produto Controlado<p>Applications 6β-Hydroxy Betamethasone can be used as analyte in analytical study for detecting betamethasone metabolites in human urine using liquid chromatography coupled to tandem mass spectrometry.<br>References Matabosch, X., et al.: Drug Testing and Analysis, 7, 663-672 (2015)<br></p>Fórmula:C22H29FO6Cor e Forma:NeatPeso molecular:408.46Olodaterol Hydrochloride
CAS:Produto Controlado<p>Applications Olodaterol is a long acting β-adrenoceptor agonist used as an inhalation for treating patients with chronic obstructive pulmonary disease (COPD).<br>References Cazzola, M., et al.: Pharmacol. Rev., 64, 450 (2012); Bouyssou, T., et al.: Bioorg. Med. Chem. Lett., 20, 1410 (2010);<br></p>Fórmula:C21H27ClN2O5Cor e Forma:Off-White To Light BrownPeso molecular:422.90Boldenone 17-Sulfate TEA
CAS:Produto Controlado<p>Applications The major metabolite of Boldenone, an anabolic steroid.<br>References Fotsis, T., et al.: J. Steroid Biochem., 28, 203 (1987), Song, Y., et al.: Arch. Pharm. Res., 23, 599 (2000), Buiarelli, F., et al.: Anal. Chim. Acta, 526, 113 (2004), Poelmans, S., et al.: Food Addit. Contam., 22, 808 (2005),<br></p>Fórmula:C19H26O5S•C6H15NCor e Forma:Off-White To BeigePeso molecular:366.47
