Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(273.647 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.605 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.602 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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2-Naphthol-d7
CAS:Produto Controlado<p>Applications 2-Naphthol-d7 has been used as a reactant for the preparation of stable isotope-labeled internal standards of PAH metabolites from urine of smokers and nonsmokers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jacob, P. III, et. al.: Anal. Chem., 79, 587 (2007)<br></p>Fórmula:C102H7HOCor e Forma:NeatPeso molecular:151.213'-Azido-3'-deoxythymidine-methyl-d3 β-D-glucuronide, Sodium Salt
CAS:Produto Controlado<p>Applications A deuterated metabolite of the potent and selective inhibitor of HIV-1 replication, AZT.This compounds contains Sodium Chloride. Water content not determined.<br></p>Fórmula:C16D3H17N5O10·NaCor e Forma:NeatPeso molecular:468.36584-Aminohippuric-d4 Acid
CAS:Produto Controlado<p>Applications Labelled 4-Aminohippuric Acid is used in the measurement of renal plasma flow as a diagnostic tool which may be applied towards kidney disorders.<br>References Phillips, R. et al.: Am. J. Physiol., 152, 523 (1948);<br></p>Fórmula:C92H4H6N2O3Cor e Forma:NeatPeso molecular:198.21(4-Bromophenyl)urea
CAS:<p>Applications (4-Bromophenyl)urea (cas# 1967-25-5) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C7H7N2OBrCor e Forma:Off-White To PurplePeso molecular:215.057-Methoxy-1-naphthaleneacetamide
CAS:Produto Controlado<p>Applications 7-Methoxy-1-naphthaleneacetamide, can be used for the synthesis of the analogs of Melatonin (M215000), containing naphthalene moiety instead of indole nucleus, having high affinity for the melatonin receptor. Agomelatine Impurity 6<br>References Tang, J. D., et al.: Org. Prep. Proc. Int., 41, 164 (2009); Sndrieux Y. J., et al.: J. Med. Chem., 35, 1484 (1992);<br></p>Fórmula:C13H13NO2Cor e Forma:NeatPeso molecular:215.2517β-Dihydro Equilin 3-Sulfate Sodium Salt
CAS:<p>Stability Hygroscopic<br>Applications A metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Fórmula:C18H21O5S·NaCor e Forma:NeatPeso molecular:372.413-Hydroxy Desloratadine
CAS:Produto ControladoFórmula:C19H19ClN2OCor e Forma:NeatPeso molecular:326.824-Hydroxy Atorvastatin Disodium Salt
CAS:<p>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),<br></p>Fórmula:C33H33FN2Na2O6Cor e Forma:White To BrownPeso molecular:618.60Urolithin C
CAS:<p>Stability Hygroscopic<br>Applications Urolithin C is used in biological studies to evaluate the metabolite antioxidant activity.<br>References Ishimoto, H., et. al.: Bioorg. Med. Chem. Lett., 21, 5901 (2011);<br></p>Fórmula:C13H8O5Cor e Forma:NeatPeso molecular:244.2Indoleacetic Acid-d4
CAS:Produto Controlado<p>Applications Labelled Indoleacetic Acid (I577343) has the potential to be used in anti-cancer therapy in conjunction with horseradish peroxidase (HRP).<br>References Kawano, T. et al.: Gen. Hypo. 60, 664 (2003);<br></p>Fórmula:C102H4H5NO2Cor e Forma:NeatPeso molecular:179.21(4-Chloro-2-methylphenoxy)acetic Acid-d3
CAS:Produto Controlado<p>Applications (4-Chloro-2-methylphenoxy)acetic Acid-d3 is the deuterated version of (4-Chloro-2-methylphenoxy)acetic Acid (C369470), which is a herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Elliott, B., et al.: Mutagenesis, 20, 3 (2005); Pfleeger, T., et al.: Environ. Toxicol. Chem., 30, 455 (2010);<br></p>Fórmula:C9H6D3ClO3Cor e Forma:NeatPeso molecular:203.642-Hydroxy Atorvastatin Calcium Salt
CAS:Produto Controlado<p>Applications di(2-Hydroxy Atorvastatin) Calcium Salt is a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Fórmula:C66H68CaF2N4O12Cor e Forma:White To YellowPeso molecular:1187.35N-Nitroso-N-ethyl Urea (Contains 40% water, 1.8 % AcOH)
CAS:Produto Controlado<p>Stability Temperature Sensitive<br>Applications Precursor of Diazoethane<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Chemistry--A European Journal, 15(12), 2923-2931, (2009), Journal of the American Chemical Society, 129(19), 6210-6215, (2007).<br></p>Fórmula:C3H7N3O2Cor e Forma:NeatPeso molecular:117.11(+)-Pinoresinol (>80% ee)
CAS:<p>Applications (+)-Pinoresinol is a lignan found in olive oil and in other plants. This phenolic compound was reported to have antioxidant and anticancer potential.<br>References Owen, R., et al.: Eur. J. Cancer, 36, 1235 (2000); Owen, R., et al.: Food Chem. Toxicol., 38, 647 (2000);<br></p>Fórmula:C20H22O6Cor e Forma:NeatPeso molecular:358.38Succinylacetone
CAS:<p>Applications Succinylacetone (SA) is a specific marker for the inherited metabolic disease, hepatorenal tyrosinemia. It was developed a stable-isotope for the determination of SA in dried blood spots (DBS) and liquid urine using a 13C4-SA as internal standard. The method was applied retrospectively and prospectively for the diagnosis of hepatorenal tyrosinemia and for follow-up of patients under treatment.<br>References Kvittingen, E., et al.: Inher. Metab. Dis., 14, 554 (1991), Lindstedt, S., et al.: Lancet, 340, 813 (1992), Schulze, A., et al.: Clin. Chem., 47, 1424 (2001), Allard, P., et al.: Clin. Biochem., 37, 1010 (2004),<br></p>Fórmula:C7H10O4Cor e Forma:White To Off-WhitePeso molecular:158.15Demethyl Benzydamine Hydrochloride
CAS:Produto Controlado<p>Applications A metabolite of Benzydamine (B209950).<br>References Kataoka, S., et al.: Chem. Pharma. Bull., 21, 358 (1973),<br></p>Fórmula:C18H22ClN3OCor e Forma:Off White SolidPeso molecular:331.84Methyl 2,3,4-Tri-O-isobutyryl-D-glucopyranuronate
CAS:Produto Controlado<p>Stability Temperature Sensitive<br>Applications Methyl 2,3,4-Tri-O-isobutyryl-D-glucopyranuronate (cas# 1190403-86-1) is a compound useful in organic synthesis.<br></p>Fórmula:C19H30O10Cor e Forma:NeatPeso molecular:418.443-Sulfo-glycodeoxycholic Acid Disodium Salt
CAS:Produto ControladoFórmula:C26H41NNa2O8SCor e Forma:NeatPeso molecular:573.653-Hydroxyglutaric Acid
CAS:<p>Applications 3-Hydroxyglutaric Acid (cas# 638-18-6) is a compound useful in organic synthesis.<br></p>Fórmula:C5H8O5Cor e Forma:White To Light OrangePeso molecular:148.11Beclomethasone 17-Propionate
CAS:<p>Impurity Beclomethasone Dipropionate EP Impurity H<br>Applications Beclomethasone 17-Propionate (Beclomethasone Dipropionate EP Impurity H) is an active metabolite of Beclomethasone Dipropionate (BDP).<br>References Soria, I., et al.: Biopharm. Drug Dispos., 19, 297 (1998), Harrison, L., et al., J. Pharm. Pharmacol., 51, 1235 (1999), Daley-Yates, P., et al.: Br. J. Clin. Pharm., 51, 400 (2001).<br></p>Fórmula:C25H33ClO6Cor e Forma:WhitePeso molecular:464.98
