Padrões Farmacêuticas

N-(Aminoethyl)-5-naphthylamine-1-sulfonic acid sodium salt (NAES) is a fluorescent dye that has been used to study the structure of proteins. NAES binds to acceptor sites on the protein, which can be either amino acid side chains or other ions in solution. The fluorescence of NAES depends on the environment and the number of acceptors present. This dye has been used in assays for staphylococcus, as it is resistant to staining by Gram stain and stains brightly with fluorescence assay. NAES has also been shown to have a high kinetic rate and sensitivity, making it an effective virus assay.

5α-Pregnan-3β-ol-20-one 3β-acetate is a synthetic steroid that is used to treat various neurological disorders, including dystonias, depression, and dyskinesias. It is an agonist of the GABA receptor and has been shown to have antidepressant effects in hamsters. 5α-Pregnan-3β-ol-20-one 3β-acetate has also been shown to have antiaggressive effects in mice and to decrease hormone levels in animals. The drug has been found to be safe for use in humans and does not affect fertility. 5α-Pregnan-3β-ol-20-one 3βacetate has been shown to be effective only when administered at high doses, which may be due to its poor oral bioavailability.

2'-Iodoacetophenone is a bioactive molecule that reacts with boronic acids to form aryl boronic acid derivatives. This reaction can be carried out in chlorobenzene or dihedral solvents, and it is scalable and applicable to a variety of boronic acids. The product of this reaction is an organocatalyst for the synthesis of bioactive molecules. 2'-Iodoacetophenone also reacts with dipole-containing additives to form dichlorodiphenyldichloroethane, which has been used as a fungicide, insecticide, and herbicide.

All-trans-Anhydro retinol is a retinoid that is biologically active as an antioxidant, with reactive properties. It has been shown to be photodecomposable in the presence of light, and it reacts rapidly with nucleophiles. All-trans-Anhydro retinol can be used as a model system for biological studies on the mechanisms of mitochondrial membrane potential and transfer reactions. All-trans-Anhydro retinol has been shown to decrease mitochondrial membrane potential in rat liver microsomes and inhibit fatty acid synthesis in liver cells, while also being a synthetic analog of all-trans retinoic acid.

Vanillic acid hydrazide is a multinuclear compound with condensation products. It has been shown to have antibacterial, anticancer and skeleton-related properties. Vanillic acid hydrazide is able to bind to the 4-hydroxybenzoic acid and introduce it into the cell in order to inhibit the synthesis of fatty acids. This compound also inhibits the growth of cancer cells by preventing their proliferation and proliferation by binding to DNA. Vanillic acid hydrazide may also bind to fatty acids on cell membranes, which would lead to a decrease in membrane fluidity and increase in membrane permeability, leading to cell death.

1-(4-Bromophenyl)-2-nitropropene is a synthetic molecule that undergoes an efficient cycloaddition reaction with aldehydes. This reaction is used to synthesize 1,3-dienes and alpha,beta-unsaturated carbonyl compounds. When the substrate is an aldehyde, the final product is a 1,3-diene. When the substrate is an alpha,beta-unsaturated carbonyl compound, the final product is an alpha,beta-unsaturated ketone.

Bisabolol is a sesquiterpene lactone that is found in plants such as chamomile and rose. Bisabolol has been shown to have amoebicidal activity in vitro, as well as antiinflammatory activity. Bisabolol has also been shown to have mitochondrial membrane potential-modulating effects and to inhibit the growth of human cancer cells. Bisabolol can act intracellularly by inhibiting protein synthesis, which may lead to apoptosis. It also inhibits the production of pro-inflammatory cytokines, such as TNF-α and IL-1β, which are involved in tumorigenesis. Bisabolol can also bind to polymyxin B and form a complex that is more effective than polymyxin B alone at killing bacteria.

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2-Vinylnaphthalene is a chemical compound that belongs to the group of polymers. It is a colorless liquid with a boiling point of 260°C and a molecular weight of 192.19 g/mol. 2-Vinylnaphthalene has been shown to be highly resistant to radiation and can be used in polymer matrices as an electron-donor material. The polymerized form of 2-vinylnaphthalene has high resistance to photochemical degradation, and exhibits fluorescence properties with excitation at 350 nm.
2-Vinylnaphthalene has also been studied as a model system for the study of ionizing radiation, where it was found to exhibit high activation energies for decomposition reactions.

L-Homocysteine thiolactone hydrochloride is a synthetic radiotracer. It has been used as a positron emission tomography (PET) radiopharmaceutical to image brain tumors and other cancers. L-homocysteine thiolactone hydrochloride is synthesized from L-cysteine and aluminium chloride. The yield of this reaction is usually low, but can be increased by addition of sodium hydroxide or tetrabutylammonium bromide. L-homocysteine thiolactone hydrochloride has been shown to be an effective radiotracer for the detection of cancerous tissue in the brain, breast, and prostate.

2,6-Dichloro-1,5-dinitronaphthalene is an organic compound that is used as a reagent for the synthesis of other compounds. It can also be used in research for the synthesis of 2,6-dichloro-1,5-dinitronaphthalene derivatives. The CAS number for this compound is 320600-07-5. This compound is a versatile building block and has many uses as a fine chemical.

Beta-tropine is a fatty acid that is synthesized from tiglic acid. It is used in sample preparation for the determination of nitrogen and carbon content and to determine the presence of ester linkages. Beta-tropine has been shown to inhibit the activity of enzymes, such as citrate lyase and malonic acid decarboxylase, which are involved in oxidative metabolism. Beta-tropine also inhibits the activity of mt2 receptors, which are involved in the regulation of blood pressure. This drug may have physiological effects on humans because it inhibits human serum aminopeptidase, an enzyme that catalyzes the hydrolysis of peptides with basic or neutral amino acids at their carboxy terminus.

Betamethasone Valerate Impurity D is a reaction component that is used as a reagent in the synthesis of compounds with a variety of activities, including antibacterial, anti-inflammatory and antiparasitic. It is also used to create a variety of building blocks and intermediates for pharmaceuticals. Betamethasone Valerate Impurity D has been shown to be an effective anti-parasitic agent against Trypanosoma cruzi and Leishmania amazonensis in vitro.

4-Chlorocinnamic acid is a malonic acid derivative and one of the cinnamic acid derivatives that has been shown to inhibit many chemical reactions. It inhibits the production of tyrosinase, which is an enzyme that catalyzes the conversion of tyrosinase to 4-hydroxycinnamic acid. 4-Chlorocinnamic acid also inhibits the growth of Candida glabrata in vitro. The effect on candida is due to its ability to inhibit the production of hydroxyl group and aromatic hydrocarbon, both of which are required for candida's survival. 4-Chlorocinnamic acid binds with aryl halide and neutral ph, preventing it from reacting with other substances.

D-alpha-tocopherol, most commonly known as vitamin E, is a natural compound with antioxidant properties. It protects the API against oxidation and side reactions with oxidative species. Moreover, when used as excipient, vitamin E is a good solubilizing agent that greatly improves the solubility of poorly water-soluble drugs.

Applications N-Acetylethylene Urea-d4 (cas# 1189701-94-7) is a compound useful in organic synthesis.

Applications Guanosine-5'-triphosphate disodium salt (CAS# 56001-37-7) is a nucleotide used in the preparation of photoreactive GTP affinity probes, and in inhibitors of eukaryotic initiation factor eIF-4E.
References George Cisar, E. A.; J. Am. Chem. Soc., 135, 4676 (2013); Ghosh, P.; et al.: Bioorg. Med. Chem. Lett., 16, 750 (2006).

6-Methyl-4-hydroxycoumarin is a coumarin derivative that has been shown to have potent inhibitory activity against both Gram-positive and Gram-negative bacteria. It also inhibits the growth of leukemia cells and shows anti-inflammatory properties. The photophysical studies of this molecule show that it has absorption bands in the visible region, which may be attributed to its hydroxyl group. 6-Methyl-4-hydroxycoumarin has also been shown to be an effective inhibitor of LPS (lipopolysaccharide)-stimulated RAW 264.7 cells, as well as benzofuran derivatives that have been shown to have inflammatory propertys.

2-Ethoxy-4-methoxycinnamic acid is a synthetic chemical with the CAS number 1372859-34-1. It is a versatile building block that can be used for the synthesis of many complex compounds. 2-Ethoxy-4-methoxycinnamic acid is one of a number of scaffolds that are useful for creating fine chemicals and research chemicals. This compound is also an intermediate in many reactions and can be used as a reagent to produce other substances.

3,5-Difluoro-4-hydroxybenzoic acid methyl ester (DFHBME) is a chemical compound that belongs to the class of useful building blocks. It is used in research as a reagent and in the synthesis of various complex compounds. DFHBME reacts with nucleophiles such as amines or alcohols to produce useful intermediates or scaffolds for organic synthesis. This compound is also useful as a speciality chemical due to its high quality and versatility.

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Sodium N-lauroylsarcosinate is a surfactant that is used in water treatment, wastewater treatment, and as a detergent. It is also used as an analytical tool for the titration calorimetry of sodium salts. Sodium N-lauroylsarcosinate is a sodium salt that belongs to the group of sodium salts. It has been shown to have biological properties such as permeability through human serum and biodegradability. The salt form of this compound has an electrochemical impedance spectrum which can be used to identify it.

4,4'-Bis(methoxycarbonyl)-2,2'-bipyridine is a ligand that can be used in cross-coupling reactions. It has been shown to bind to metal ions and form complexes with the ligands. 4,4'-Bis(methoxycarbonyl)-2,2'-bipyridine has a constant value for maximizing the yield of the reaction and is luminescent. This product also has photophysical properties that allow it to be utilized in voltammetry studies. The transfer of this product can be optimized by using chromophores or catalysis. 4,4'-Bis(methoxycarbonyl)-2,2'-bipyridine provides a means for cross-coupling reactions using electrochemical studies and dichroism.

N,N'-Di-(tert-Butoxycarbonyl)thiourea is a sterically bulky anion that has been synthesized to interact with amines and amido groups. It has been shown to be a good substrate for p-nitrophenyl phosphate, which is an important molecule in the metabolism of melanoma tumor cells. N,N'-Di-(tert-Butoxycarbonyl)thiourea has also been used as a synthetic building block for conjugates with other molecules. This molecule is able to form supramolecular complexes and may be useful in kinetic studies. The most interesting application of this molecule is its use in the efficient method of removing mercury from water, which is accomplished by oxidation of mercuric chloride by N,N'-Di-(tert-Butoxycarbonyl)thiourea.

3-(4-Methylbenzylidene)camphor is a chemical compound that has two isomers, alpha and beta. It can be found in biological samples, such as human urine or wastewater, and can be used for the treatment of skin cancer. 3-(4-Methylbenzylidene)camphor is prepared by extraction from a dry sample with an organic solvent. The extraction process requires a hydroxyl group to react with the dry sample and create a liquid. The resulting liquid is then evaporated to leave behind the extract. The kinetic data of 3-(4-Methylbenzylidene)camphor was determined by measuring its rate of reaction with an analytical method. The rate of reaction increased as the concentration increased to a constant value at high concentrations, which suggests that it may have some occlusive properties in humans due to its tendency to bind to plasma proteins.

1-(Trimethylsilyl)-2-naphthyl Trifluoromethanesulfonate is a solvent that has been used for the synthesis of oxygen heterocycles. It is also used as a reagent to cleave bonds in organic molecules, such as alkene, solvents, aldehydes and activated esters. This compound is an unsymmetrical nucleophile that reacts with electron-poor alkenes to generate an unsaturated bond between two carbons. Mechanistic studies have shown that the reaction proceeds through a concerted mechanism involving the formation of a covalent phosphine intermediate.

4'-Bromo-3'-methylacetophenone, 75% is a high quality reagent that is a useful intermediate for the synthesis of complex compounds. It has CAS No. 37074-40-1 and can be used as a fine chemical or speciality chemical in research. This product is also a versatile building block that can be used as an intermediate in reactions and as a reaction component.

1-(3-Bromophenyl)-2-nitropropane is a fine chemical that is used as a building block in the synthesis of complex organic compounds. It can be used as a reagent and speciality chemical with high quality. 1-(3-Bromophenyl)-2-nitropropane is versatile for use in reactions, such as coupling reactions, because it can be used as an intermediate or scaffold to create many different compounds. CAS No.: 155988-18-4

Naphthalene 1,4-dicarboxaldehyde is a low energy focusing molecule that is used in macrocyclic compounds. It can be oxidized to form naphthalene 1,4-diacid and naphthalene 1,4-diketone. This compound has been used to synthesize the triarylmethane dye viologen by Wittig reaction. Naphthalene 1,4-dicarboxaldehyde has also been shown to have fluorescence properties and can be useful for chemiluminescence. Naphthalene 1,4-dicarboxaldehyde reacts with sulfide or amine groups to form sulfides or amines respectively.

O-Phospho-L-tyrosine is a phosphorylated form of L-tyrosine. It is used as an immunogen in the production of monoclonal antibodies. O-Phospho-L-tyrosine has also been shown to inhibit the enzyme indole alkaloids, which are responsible for the development of oral pathogens. The dephosphorylation of O-Phospho-L-tyrosine by tyrosine phosphatases leads to its conversion back to L-tyrosine. This compound can be detected by chromatographic analysis and is commonly used in analytical methods to identify natural compounds.

4-Aminosalicylic acid sodium salt dihydrate is a molecule that has been shown to be useful for the diagnosis of viral, autoimmune, and cancerous diseases. It is a diagnostic agent that can be used in both the diagnosis and treatment of bowel disease. 4-Aminosalicylic acid sodium salt dihydrate can also be used to treat cavity formation in teeth. It binds to fatty acids in the target tissue, which leads to cell death by apoptosis. This drug has been shown to be effective against inflammatory bowel disease (IBD) as well as other types of bowel disease. This drug has been shown to have no adverse effects on healthy cells or tissues, but it may cause kidney toxicity when taken orally or injected intravenously.

2,2'-Dihydroxybenzophenone is a light-absorbing compound that belongs to the class of dibenzophenones. It has been shown to have cancer-cell inhibitory effects and its anti-tumor effects are due to its ability to inhibit DNA synthesis in tumor cells. 2,2'-Dihydroxybenzophenone has been shown to bind with proteins through hydrogen bonding interactions at the carbonyl group and the hydroxy group. It also has a strong absorption band in the UV region, which makes it useful for UV curing of polymers. This compound can be used as an antioxidant in food products because it does not react with other molecules.

N-a-t-Boc-N-g-trityl-L-asparagine is a recombinant human protein that has been synthesized in E. coli. It is a peptide with 17β-estradiol at its C terminus, and it binds to the oestrogen receptor α (ERα) via hydrogen bonding interactions. The linker between the asparagine and estradiol is a Boc group that can be removed by protease activity, revealing the active form of 17β-estradiol. ERα ligates to N-a-t-Boc-N-g-trityl L asparagine with high affinity, and this interaction is reversible. The linker also contains a functional group for surface attachment, which may be used to attach this peptide to a solid support or tissue culture substrate for use in cell cultures.
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5-Amino-o-cresol is a chemical compound that is used in analytical chemistry as an aminophenol. It reacts with ethylene diamine to form a red dye called 5-aminonaphthalene-2,7-disulphonic acid (5ANDS). The reaction solution can be used to identify the presence of bacterial DNA. 5-Amino-o-cresol has been shown to have genotoxic effects, which may lead to skin cancer or skin damage. This chemical also has toxicological properties and can cause skin irritation at high concentrations.

2'-Fluoro-4'-hydroxyacetophenone is a glycosylated molecule that is used in phase transfer catalysis. It is a glycoside that can undergo the glycosylation reaction and can be used as a phase transfer reagent. 2'-Fluoro-4'-hydroxyacetophenone has been studied for its potential use in the synthesis of xylosides and selenadiazoles. In addition, it has shown anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

3,3'-Diaminobenzidine tetrahydrochloride or DAB hydrochloride is the hydrochloride salt of biphenyl tetra-aniline. DAB hydrochloride is a water-soluble formulation of DAB and is used in immunohistochemical staining of nucleic acids and proteins. DAB hydrochloride is used in Alzheimer's disease research, Aβ protein amyloid plaques are targeted by a primary antibody, and subsequently by a secondary antibody, which is conjugated with a peroxidase enzyme. This will bind DAB as a substrate and oxidize causing a colour change. 3,3’-Diaminobenzidine tetrahydrochloride is also available as the tetrahydrochloride hydrate and as the free base.

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3,3'-Diheptyloxacarbocyanineiodide (DHCI) is a fluorescent probe that is used in the treatment of solid tumours. It is taken up by tumor cells and causes them to fluoresce, which can be seen under a microscope. DHCI has been shown to be effective against hypoxic tumours and tumors with low oxygen levels due to its ability to penetrate tumor cells and deliver oxygen. The uptake of DHCI by cancer cells is also dependent on the permeability of the blood vessels present in the tumor. This drug has been shown to have a large therapeutic window for treatment of solid tumours.

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3,5-Dimethoxy-4-methylbenzoic acid methyl ester (DMMBME) is a synthetic compound that is used as an immunogen to generate antibodies against fungal proteins. DMMBME is specifically used to identify the presence of bryoria and australian fungi in plants. The chemical structure of DMMBME can be oxidized by depsidones, which leads to the production of reactive oxygen species that are believed to be responsible for the oxidative coupling of target proteins. This reaction can be catalyzed by a number of enzymes such as nidulin, which is found in plant roots.

2-(2',3',4'-Trihydroxybutyl)quinoxaline is a model system for the glyoxal-glycolaldehyde reaction. This reaction is important in the formation of organic acids and hydroxycarbonyl compounds. The kinetic of this reaction has been studied using glyoxal, glycolaldehyde, and hydroxycarboxylic acid as substrates. Reaction intermediates were identified by multiresponse techniques. Kinetic parameters were determined by modelling and kinetic experiments at different temperatures and concentrations.

2-Amino-4'-chloroacetophenone hydrochloride is a cytotoxic compound that inhibits the polymerization of tubulin. It has been shown to have cytotoxic effects and inhibit the growth of cancer cells in vitro at low micromolar concentrations. 2-Amino-4'-chloroacetophenone hydrochloride is a member of the cytotoxic class of compounds and can be used to slow or stop cell division by inhibiting the production of proteins vital for cell division, such as tubulin. This effect is due to its ability to bind to the beta subunit of tubulin, which disrupts its structure and prevents polymerization from occurring.

1,7-Naphthyridin-8(7H)-one is a polycyclic compound that has been used as an intermediate in the synthesis of a variety of other compounds. It is also used as an iterative reagent for the annulation reactions of cyclic olefins. It can be prepared by oxidative annulation between picolinamide and 1,2,3,4-tetrahydroquinoline. The regioselectivity of this reaction can be controlled by using rhodium or copper catalysts.

N-Boc-endo-3-aminotropane is a useful building block for the synthesis of a variety of chemical compounds. It is a versatile intermediate for the synthesis of diverse chemical compounds and is also used in research as a reagent. N-Boc-endo-3-aminotropane has been shown to be highly reactive and to undergo many reactions, including nucleophilic substitution and addition reactions. The compound can be reacted with alkyl halides to form amines, or with nitroalkanes to form oximes. N-Boc-endo-3-aminotropane can also react with anhydrides or acid chlorides to form carboxylic acids, or with sulfonyl chlorides to form sulfonamides. This compound also reacts with thiols or alcohols to form thioethers and ethers respectively.

Betaine hydrochloride is a betaine prodrug that is metabolized by the body to form glycine and choline. Betaine hydrochloride has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit surfactant sodium dodecyl (SDS) from activating enzymes such as polymerase chain reaction (PCR). Betaine hydrochloride also has been shown to improve disease activity in bowel disease patients and can be used as a dietary supplement for individuals with low levels of choline.

1-(2-Chloro-4-fluorophenyl)-2-nitropropene is a versatile building block that can be used to produce a variety of compounds with various properties. It is a high quality, reagent grade chemical that is useful for research and development purposes. This compound has been shown to be an effective intermediate in the synthesis of complex compounds, such as pharmaceuticals and pesticides.