Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(274.948 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.606 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.879 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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Methyl 3,4,5-Trimethoxycinnamate (>85%)
CAS:Produto Controlado<p>Applications METHYL 3,4,5-TRIMETHOXYCINNAMATE (cas# 20329-96-8) is a useful research chemical.<br></p>Fórmula:C13H16O5Pureza:>85%Cor e Forma:NeatPeso molecular:252.261, N2-Etheno-2'-deoxyguanosine-13C5
CAS:Produto Controlado<p>Applications 1, N2-Etheno-2’-deoxyguanosine-13C5 is caused by exposure to pollutants. It is an isotopically labeled analog of the 2’-Deoxyguanosine adduct.<br></p>Fórmula:C713C5H13N5O4Cor e Forma:NeatPeso molecular:296.233-(Difluoromethyl)-1H-pyrazole-4-carboxylic Acid
CAS:Produto Controlado<p>References Zeun, R., et al.: Pest Manag. Sci., 69, 527 (2013); Oostendorp, M., et al.: Phytopathology, 101, S133 (2011); Olaya, G., et al.: Phytopathology, 101, S132 (2011)<br></p>Fórmula:C5H4F2N2O2Cor e Forma:NeatPeso molecular:162.092'-Deoxyadenosine-15N1
CAS:Produto Controlado<p>Applications 2'-Deoxyadenosine-15N1 is an intermediate in the synthesis of 8-Oxo-2’-deoxyguanosine-13C,15N2 (O850252). A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro.<br>References Ueda, T., et al.: Chem. Pharm. Bull., 26, 2122 (1978), Jiang, F., et al.: Nature, 183, 382 (1996),<br></p>Fórmula:C10H1315NN4O3Cor e Forma:NeatPeso molecular:252.2357-Nitrocoumarin
CAS:Produto Controlado<p>Applications Coumarin derivatives were made for trial as bacteriostats.<br></p>Fórmula:C9H5NO4Cor e Forma:NeatPeso molecular:191.142'-Hydroxyflavone
CAS:Produto Controlado<p>Applications 2'-Hydroxyflavone (cas# 35244-11-2) is a useful research chemical.<br></p>Fórmula:C15H10O3Cor e Forma:NeatPeso molecular:238.238Guanosine-13C5 5'-Monophosphate
CAS:Produto Controlado<p>Applications Guanosine-13C5 5’-Monophosphate is an isotope labelled version of Guanosine 5’-Monophosphate (G844708), a nucleotide with an umami taste.<br>References Charve, Josephine, et al.: J. of Agric. and Food Chem., 66(8), 1863-1871 (2018)<br></p>Fórmula:C513C5H14N5O8PCor e Forma:White To Light YellowPeso molecular:368.18Hydroxy Dehydro Nifedipine Lactone
CAS:Produto ControladoFórmula:C16H12N2O6Cor e Forma:NeatPeso molecular:328.28Salicylic Acid-13C6
CAS:<p>Applications Labelled acetylsalicylic acid impurity B.<br>References Walter, M., et al.: Eur. J. Biochem., 1996, 239, 281 (1996), Bantignies, B., et al.: Plant Mol. Biol., 42, 871 (2000), Bais, H., et al.: J. Biol. Chem., 278, 32413 ( 2003), Finkler, C., et al.: Genetica, 124, 117 (2005),<br></p>Fórmula:C6CH6O3Cor e Forma:NeatPeso molecular:144.083'-Aminoacetophenone
CAS:<p>Applications 3'-Aminoacetophenone has potential anti-bacterial properties in addition to being used in the synthesis of selective antagonists at human A2B adenosine receptors. As well, it is used in the synthesis of HIV-1 Integrase Inhibitors.<br>References Kim, Y.C. et al.: J. Med. Chem., 43, 1165 (2000); Pais, G.C.C. et al.: J. Med. Chem., 45, 3184 (2002);<br></p>Fórmula:C8H9NOCor e Forma:NeatPeso molecular:135.16Betamethasone 9,11-Epoxide 17,21-Dipropionate
CAS:Produto Controlado<p>Impurity Betamethasone Dipropionate EP Impurity J<br>Applications Betamethasone 9,11-Epoxide 17,21-Dipropionate (Betamethasone Dipropionate EP Impurity F) is an impurity of Betamethasone (B327000), an antiinflammatory agent.<br>References Shou, M., et al.: J. Pharm. Biomed. Anal., 50, 356 (2009),<br></p>Fórmula:C28H36O7Cor e Forma:White To Off-WhitePeso molecular:484.581-(Chloromethyl)naphthalene
CAS:Produto Controlado<p>Applications 1-(Chloromethyl)naphthalene is used in the identification of Novel p38α MAP Kinase Inhibitors. It is also used in the Identification of 1,5-Naphthyridine derivatives as a novel series of potent and selective TGF-β type I receptor inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gill, A., et al.: J. Med. Chem., 48, 414 (2005); Gellibert, F., et al.: J. Med. Chem., 47, 4494 (2004)<br></p>Fórmula:C11H9ClCor e Forma:NeatPeso molecular:176.64Azoniaspironortropanol-d8 Chloride
CAS:Produto Controlado<p>Applications Azoniaspironortropanol-d8 Chloride is the labeled analogue of Azoniaspironortropanol Chloride (A965125), an intermediate used for the synthesis of Trospium Chloride (T892800), an Antispasmodic, used in treatment of urinary incontinence.<br>References Antweiler, H., et al.: Arzneim.-Forsch., 16, 1581 (1966); Lux, G., et al.: Fortschr. Med., 96, 2113 (1978); Madersbacher, H., et al.: Br. J. Urol., 75, 452 (1995); Zinner, N.R., et al.: Expert Opin. Pharmacother., 6, 1409 (2005)<br></p>Fórmula:C11D8H12NO·ClCor e Forma:NeatPeso molecular:225.7854-Nitro-4’-aminodiphenyl Sulfone
CAS:<p>Applications An intermediate in the synthesis of the Daspone metabolite.<br></p>Fórmula:C12H10N2O4SCor e Forma:NeatPeso molecular:278.28N-Methyl-N-nitroso Urea (Wetted with water >20%)
CAS:Produto Controlado<p>Stability Temperature Sensitive<br>Applications Precursor of Diazomethane. It has a cytotoxicity effect.This product contains an undetermined amount of water.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Huggins, C., et al.: J. Exp. Med., 131, 321 (1970), Gullino, P.M., et al.: J. Natl. Cancer Inst., 54, 401 (1975),<br></p>Fórmula:C2H5N3O2Cor e Forma:Off-White To Light BeigePeso molecular:103.08O,O-Dimethyl-d6 Dithiophosphate Ammonium Salt
CAS:Produto Controlado<p>Applications O,O-Dimethyl-d6 Dithiophosphate is the isotope labelled analog of O,O-Dimethyl Dithiophosphate (3, an dimethyl phosphorodithiolate derivatives used as insecticides.<br></p>Fórmula:C2H4D6NO2PS2Cor e Forma:Off-White To Light YellowPeso molecular:181.25apo-Ipratropium Bromide (mixture of stereoisomers)
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications 8-Isopropyl-8-methyl-3-endo((2-phenylacryloyl)oxy)-8-azabicyclo[3.2.1]octan-8-ium Bromide is an intermediate used in the preparation of quaternary salts of alkaloids.<br>References Ivanov, V., et al.: Farmatsiya17, 18 (1967)<br></p>Fórmula:C20H28NO2·BrCor e Forma:NeatPeso molecular:394.34Faropenem Sodium Salt Hemipentahydrate
CAS:Produto ControladoFórmula:C12H14NO5SNaH2OCor e Forma:NeatPeso molecular:704.672,6-Diiodo-4-nitrophenol
CAS:<p>Stability Light Sensitive<br>Applications 2,6-Diiodo-4-nitrophenol is useful for statistical methods for developing QSARs to predict toxicity of phenols to Tetrahymena pyriformis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cronin, M., et al.: Chemosphere, 49, 1201 (2002);<br></p>Fórmula:C6H3I2NO3Cor e Forma:NeatPeso molecular:390.9(+)-Pinoresinol (>80% ee)
CAS:<p>Applications (+)-Pinoresinol is a lignan found in olive oil and in other plants. This phenolic compound was reported to have antioxidant and anticancer potential.<br>References Owen, R., et al.: Eur. J. Cancer, 36, 1235 (2000); Owen, R., et al.: Food Chem. Toxicol., 38, 647 (2000);<br></p>Fórmula:C20H22O6Cor e Forma:NeatPeso molecular:358.38methyl 1,2,3,4-tetrahydronaphthalene-1-carboxylate
CAS:Produto Controlado<p>Applications methyl 1,2,3,4-tetrahydronaphthalene-1-carboxylate (cas# 17502-86-2) is a useful research chemical.<br></p>Fórmula:C12H14O2Cor e Forma:ColourlessPeso molecular:190.24Coproporphyrin III Dihydrochloride
CAS:<p>Applications Coproporphyrin III can be used as a biomarker for environmental toxicity and susceptibility in autism.<br>References Geier, D. A., et al.: J. of the Neuro. Sci., 280(1-2), 101-108 (2009)<br></p>Fórmula:C36H38N4O8·2Cl2HCor e Forma:NeatPeso molecular:727.63Perillen, >90%
CAS:Produto Controlado<p>Stability Volatile<br>Applications PERILLEN (cas# 539-52-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C10H14OPureza:>90%Cor e Forma:NeatPeso molecular:150.22Sodium Chlorite (Technical Grade)
CAS:<p>Applications Sodium Chlorite is used as a bleaching agent for cotton textiles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shenai, V.A., Pai, S.M.: Textile Dyer Printer, 3, 153 (1969)<br></p>Fórmula:ClO2·NaCor e Forma:NeatPeso molecular:90.4416Sodium 2,2'-Methylene-bis(4,6-di-tert-butylphenyl)phosphate
CAS:Produto Controlado<p>Applications Sodium 2,2'-Methylene-bis(4,6-di-tert-butylphenyl)phosphate is an organophosphate nucleating agent.<br>References Li, J., et al.: Suliao, 43, 47-50 (2014);<br></p>Fórmula:C29H42O4P·NaCor e Forma:White PowderPeso molecular:508.607-Methoxy-3,4-dihydro-1-naphthalenyl-acetonitrile
CAS:Produto Controlado<p>Applications 7-Methoxy-3,4-dihydro-1-naphthalenyl-acetonitrile (cas# 861960-34-1) is a compound useful in organic synthesis.<br></p>Fórmula:C13H13NOCor e Forma:NeatPeso molecular:199.25D-(+)-Carvone
CAS:<p>Applications D-(+)-Carvone, is used for the synthesis of (-)-terpestacin, a fungal metabolite with anticancer activity.It is also found in the essential oils of the in vitro M. longifolia plantlets and callus, that can be used as a potential source of a safe flavouring agent.<br>References Jin , Y., et al.: Org. Biomol. Chem., 10(28), 5452 (12012); Morcia, C., et al.: Acta. Biochimica. Polonica., 58(4), 581 (2011);<br></p>Fórmula:C10H14OCor e Forma:NeatPeso molecular:150.225’-Tosyl Adenosine
CAS:Produto Controlado<p>Applications 5’-Tosyl Adenosine (cas# 5135-30-8) is a compound useful in organic synthesis.<br></p>Fórmula:C17H19N5O6SCor e Forma:NeatPeso molecular:421.434-Nitrophenol Sodium Salt Dihydrate
CAS:Produto ControladoFórmula:C6H4NNaO3·2(H2O)Cor e Forma:NeatPeso molecular:161.09 + 2(18.02)Desacetyl Rifampicin Quinone
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Desacetyl Rifampicin Quinone is an impurity of Rifampicin (R508000).<br>References Wilson, W.L. et al.: J. Chrom., 144, 270 (1977);<br></p>Fórmula:C41H54N4O11Cor e Forma:NeatPeso molecular:778.891-Naphthol-4-sulfonic Acid Sodium Salt
CAS:Produto Controlado<p>Applications 1-NAPHTHOL-4-SULFONIC ACID SODIUM SALT (cas# 6099-57-6) is a useful research chemical.<br></p>Fórmula:C10H7NaO4SCor e Forma:NeatPeso molecular:246.219-cis-Retinyl Stearate-d5
CAS:Produto Controlado<p>Applications 9-cis-Retinyl Stearate-d5, is the labeled analogue of 9-cis-Retinyl Stearate (R275600), a fatty acid ester of Retinol isomer, found mainly in the retina.<br>References Bridges, C.D.B., et al.: Methods Enzymol., 81, 463 (1982),<br></p>Fórmula:C38D5H59O2Cor e Forma:NeatPeso molecular:557.944Isoxanthopterin
CAS:Produto Controlado<p>Applications Isoxanthopterin is a metabolite found in brown rice.<br>References Wang, C., et al.: J. Sci. Food Agric., 100, 4364 (2020)<br></p>Fórmula:C6H5N5O2Cor e Forma:NeatPeso molecular:179.14Bis(heptadecafluorooctyl)phosphinic Acid
CAS:Produto Controlado<p>Applications Bis(heptadecafluorooctyl)phosphinic Acid is an intermediate used in the synthesis of Bis(heptadecafluorooctyl)phosphinic Acid Sodium Salt (B443750), which is a polyfluoroalkyl phosphoric acid that was examined as an environmental toxic compound in lakes.<br>References Guo, R., et al.: Anal. Bioanal. Chem., 404, 2699 (2012); Lee, H., et al.: Environ. Sci. Technol., 45, 8067 (2011); D’eon, J.C., et al.: Envrion. Toxciol. Chem., 29, 1319 (2010);<br></p>Fórmula:C16HF34O2PCor e Forma:NeatPeso molecular:902.11-Naphthalenemethanol-d7
CAS:Produto Controlado<p>Applications 1-Naphthalenemethanol-d7 (cas# 1189876-86-5) is a compound useful in organic synthesis.<br></p>Fórmula:C11H3D7OCor e Forma:Light BrownPeso molecular:165.24Ciprofibrate Ethyl Ester
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Ciprofibrate Ethyl Ester is an impurity of ciprofibrate(C482475) is a hypolipemic agent, related structurally to Clofibrate (C586910). Ciprofibrate is used as an antilipemic.<br>References Davison, C., et al.: Drug. Metab. Dispos., 3, 520 (1975), Arnold, A., et al.: J. Pharm. Sci., et al.: 68, 1557 (1979), Tuchman-Duplessis, H., et al.: Toxicology, 12, 1 (1979),<br></p>Fórmula:C15H18Cl2O3Cor e Forma:Colourless To Off-WhitePeso molecular:317.21Methyl Benzilate
CAS:Produto Controlado<p>Applications Methyl Benzilate is a reactant in the synthesis of Trimethadione (T796155), an anticonvulsant and antiepileptic agent used in the treatment of pregnant women. Prenatal exposure to snti-epileptic drugs (AEDs) has indicated increased risk of major or minor congenital malformation.<br>References Pastore, V., et. al.: Bioorg. Med. Chem., 21, 841 (2013); Ahir, B. et al.: Toxicol. Vitro., 28, 948 (2014); Pastore, V. et al.: Bioorg. Med. Chem., 21, 841 (2013)<br></p>Fórmula:C15H14O3Cor e Forma:Off White PowderPeso molecular:242.27p-Azidoacetophenone
CAS:Produto Controlado<p>Applications p-Azidoacetophenone (cas# 20062-24-2) is a compound useful in organic synthesis.<br>References Zarghi, A., et al.: Bioorg. Med. Chem., 14, 7044 (2006), Cline, M., et al.: Biochem., 46, 1981 (2007),<br></p>Fórmula:C8H7N3OCor e Forma:NeatPeso molecular:161.168-Oxo-2’-deoxyguanosine-13C,15N2
CAS:Produto Controlado<p>Applications A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro.<br>References Ueda, T., et al.: Chem. Pharm. Bull., 26, 2122 (1978), Jiang, F., et al.: Nature, 183, 382 (1996),<br></p>Fórmula:C913CH13N315N2O5Cor e Forma:NeatPeso molecular:286.222,2,6,6-Tetramethyl-4-piperidyl Methacrylate
CAS:Produto Controlado<p>Applications It is used as cholesterol-lowering agent.<br>References Bauer, D., et al.: Polym Deg. Stab., 48, 259 (1995), Nakahara, K., et al.: Chem. Physics Lett., 359, 351 (2002),<br></p>Fórmula:C13H23NO2Cor e Forma:WhitePeso molecular:225.33(6R)-6-Methyl-octanoic Acid
CAS:Produto Controlado<p>Applications (6R)-6-Methyl-octanoic Acid is an intermediate in synthesizing Colistin A Sulfate Hydrate (C641510), used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria.<br>References Wallace, S. et al.: J. Pharm. Sci., 102, 1578 (2013); Suzuki, T., et al.: J. Biochem., 54, 25 (1963); Barnett, M., et al.: Br. J. Pharmacol. Chemother., 23, 552 (1964); Littlewood, J, M., et al.: Respir. Med., 94, 632 (2000); Li, J., et al.: Int. J. Antimicrob. Ag., 25, 11 (2005); Tsubery, H. et al.: Antimicrob. Agents Chemother., 49, 3122 (2005)<br></p>Fórmula:C9H18O2Cor e Forma:NeatPeso molecular:158.24(-)-β-Copaene
CAS:Produto Controlado<p>Applications (-)-β-Copaene is a natural product, present in very small quantities in numerous plants and trees. It is used in the investigations of acid catalyzed, photochemical and thermally induced rearrangements of Germacrene D (G367765).<br>References Bulow, N., Konig, A.: Phytochemistry, 55, 141 (2000);<br></p>Fórmula:C15H24Cor e Forma:NeatPeso molecular:204.3514-(4-Nitrophenyl)-3-morpholinone
CAS:Produto ControladoFórmula:C10H10N2O4Cor e Forma:NeatPeso molecular:222.20Mevastatin Hydroxy Acid Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications An active carboxylate of Mevastatin (M340500). It is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase with hypocholesterolemic activity. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood.<br>References Endo, A. et al.: Atheroscler. Supp., 5, 39 (2004); Hosobuchi, M. et al.: J. Ferm. Bioeng., 76, 470 (1993);<br></p>Fórmula:C23H35O6·NaCor e Forma:NeatPeso molecular:430.51Clocortolone Acetate
CAS:Produto Controlado<p>Applications Clocortolone Acetate is an intermediate in the synthesis of Clocortolone (C583800), an corticosteroid used in the treatment of skin inflammmation and other skin conditions arising for dermatoses.<br>References Rehm, K. et al.: Pharmaz. Zeit., 127, 888 (1982);<br></p>Fórmula:C24H30ClFO5Cor e Forma:NeatPeso molecular:452.946β-Hydroxy Norethindrone Acetate
CAS:Produto Controlado<p>Impurity Norethindrone Acetate EP Impurity F<br>Applications 6β-Hydroxy Norethindrone Acetate (Norethindrone Acetate EP Impurity F) is an oxidative product of the drug Norethindrone (N676000). Norethindrone impurity.<br>References Reif, V., et al.: Pharmaceutical Res., 4, 54 (1987), Rao, P., et al.: Steroids, 59, 621 (1994),<br></p>Fórmula:C22H28O4Cor e Forma:Off-WhitePeso molecular:356.46ethyl (4-nitrophenyl)carbamate
CAS:Produto Controlado<p>Applications ethyl (4-nitrophenyl)carbamate (cas# 2621-73-0) is a useful research chemical.<br></p>Fórmula:C9H10N2O4Cor e Forma:NeatPeso molecular:210.18Mefruside
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Mefruside is a diuretic used for the treatment of edema and hypertension.<br>References Johansen, A., et al.: Euro. J. Epidemiol., 27, 63 (2012); Hasegawa, Y., et al.: Blood. Press. Supple., 1, 10 (2010);<br></p>Fórmula:C13H19ClN2O5S2Cor e Forma:Off-WhitePeso molecular:382.882-Hydroxy Oleic Acid
CAS:Produto Controlado<p>Applications An oleic acid synthetic analog that is an effective non-toxic anticancer drug with a wide spectrum against different types of cancer. An antihypertensive.<br>References Llado, V. et al.: J. Cell. Molec. Med., 14, 659 (2010); Alemany, R. et al.: J. Lip. Res., 47, 1762 (2006); Martinez, J. et al.: J. Pharmacol. Exp. Therap., 315, 466 (2005);<br></p>Fórmula:C18H34O3Cor e Forma:Off White SolidPeso molecular:298.46
