Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(275.009 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.605 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.880 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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Terazosin-md
Produto Controlado<p>Applications Terazosin-md is an analog of Terazosin (T105000) which is an α1-adrenergic receptor antagonist alleviating organ damage in studies done on rodent models of stroke and sepsis and has potential to be used for treatment for diseases.<br>References Chen, X., et al.: Nat. Chem. Biol, 11, 19 (2015)<br></p>Fórmula:C20H26N4O4Cor e Forma:NeatPeso molecular:386.445(BetaR,DeltaR,1S,2S)-1,2-Dihydro-β,δ,6-trihydroxy-2-methyl-1-naphthaleneheptanoic Acid Sodium Salt (Pravastatin Impurity)
CAS:Produto Controlado<p>Applications Pravastatin impurity.<br>References Muramatsu, S., et al.: Biol. Pharm. Bull., 20, 1199 (1997), Serajuddin, A., et al.: J. Pharm. Sci., 88, 696 (1999),<br></p>Fórmula:C18H23O5·NaCor e Forma:NeatPeso molecular:342.36Methyl-2-naphthalenemethylamine Hydrochloride
CAS:Produto Controlado<p>Applications An intermediate in the preparation of detoxification inhibitors of the crucifer phytoalexin Brassinin, as potential fungicides against Leptosphaeria maculans.<br>References Gaspari, P., et al.: J. Med. Chem., 49, 684 (2006), Pedras, M., et al.: Bioorg. Med. Chem., 14, 714 (2006),<br></p>Fórmula:C12H14ClNCor e Forma:NeatPeso molecular:207.7(2-Naphthyloxy)acetyl Chloride
CAS:Produto Controlado<p>Applications (2-Naphthyloxy)acetyl Chloride serves as one of the reagents for the discovery of indoline-2-carboxamide derivatives as new classs of brain-penetrant inhibitors of trypanosoma brucei. Also in preparation and antibacterial activity of N-(phenylquinazolinonyl) aryl-amides by amidation of amino(phenyl)quinazolone with aroyl chlorides<br>References Cleghorn, L. A., et al.: J. Med. Chem., 58, 7695 (2015); Prajapati, A. K., et al.: Indian J. Heterocycl. Chem., 19, 269 (2010)<br></p>Fórmula:C12H9ClO2Cor e Forma:NeatPeso molecular:220.6521,3-Diacetyl Aloe-emodin
CAS:Produto Controlado<p>Applications 1,3-Diacetyl Aloe-emodin is an intermediate in the synthesis of Aloe Emodin 8-Glucoside which is a anthraquinone glycoside that was investigated for antioxidant activities and neuroprotective properties.<br>References El-Toumy, S.A., et al.: Carb. Res. 360, 47 (2012); Xiang, L., et al: TsingHua. Sci. Tech., 10, 426 (2005); Shi, Y.Q., et al: Anticancer. Res., 21, 2847 (2001);<br></p>Fórmula:C10H17BO2Cor e Forma:NeatPeso molecular:180.0525’-Tosyl Adenosine
CAS:Produto Controlado<p>Applications 5’-Tosyl Adenosine (cas# 5135-30-8) is a compound useful in organic synthesis.<br></p>Fórmula:C17H19N5O6SCor e Forma:NeatPeso molecular:421.436α-Hydroxy Progesterone (>80%)
CAS:Produto ControladoFórmula:C21H30O3Pureza:>80%Cor e Forma:NeatPeso molecular:330.46(±)-trans-α-Bergamotene
CAS:Produto Controlado<p>Applications (±)-trans-α-Bergamotene is an essential oil from medicinal plants of Cameroon.<br>References Boyom, F. F., et al.: Phytochem., 64, 1269 (2003);<br></p>Fórmula:C15H24Cor e Forma:NeatPeso molecular:204.351Perilla Ketone
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Perilla Ketone is an oil from Perilla frutescens which is very toxic as it is a potent pulmonary edemagenic agent for laboratory animals and livestock. This compound is commonly used in oriental foods.<br>References Wilson, B.J., et al.: Science, 197, 573 (1997)<br></p>Fórmula:C10H14O2Cor e Forma:NeatPeso molecular:166.22Indole-3-acetic acid Sodium Salt
CAS:Produto Controlado<p>Stability Temperature Sensitive<br>Applications Indole-3-acetic acid is a plant growth regulator. It induces cell division and cell elongation that promotes plant growth.<br>References Fawcett, C., et al.: Nature, 178, 972 (1956); Fawcett, C., et al.: Annals Appl. Bio., 43, 342 (1955); Korshak, V., et al.:Vysokomolekulyarnye Soedineniya, Seriya B: Kratkie Soobshcheniya, 22, 791 (1980)<br></p>Fórmula:C10H8NNaO2Cor e Forma:White To Off-WhitePeso molecular:197.174-(S)-1-Des(methylamine)-1-oxo-2-(R,S)-hydroxy Sertraline
CAS:Produto ControladoFórmula:C16H12Cl2O2Cor e Forma:NeatPeso molecular:307.1722-Hydroxy Mifepristone
CAS:Produto Controlado<p>Applications A metabolite of Mifepristone.<br>References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Fórmula:C29H35NO3Cor e Forma:NeatPeso molecular:445.59N-Desmethyl Clomipramine Hydrochloride
CAS:Produto Controlado<p>Applications A metabolite of Clomipramine.<br>References McTavish, D., et al.: Drugs, 39, 136 (1990), Chauret, N., et al.: Drug Metab. Dispos., 25, 1130 (1997), Gex-Fabry, M., et al.: Ther. Drug Monit., 22, 701 (2000), Herrera, D., et al.: J. Clin. Pharmacol., 40, 1488 (2000),<br></p>Fórmula:C18H21ClN2·ClHCor e Forma:Off-WhitePeso molecular:337.29(6R)-6-Methyl-octanoic Acid
CAS:Produto Controlado<p>Applications (6R)-6-Methyl-octanoic Acid is an intermediate in synthesizing Colistin A Sulfate Hydrate (C641510), used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria.<br>References Wallace, S. et al.: J. Pharm. Sci., 102, 1578 (2013); Suzuki, T., et al.: J. Biochem., 54, 25 (1963); Barnett, M., et al.: Br. J. Pharmacol. Chemother., 23, 552 (1964); Littlewood, J, M., et al.: Respir. Med., 94, 632 (2000); Li, J., et al.: Int. J. Antimicrob. Ag., 25, 11 (2005); Tsubery, H. et al.: Antimicrob. Agents Chemother., 49, 3122 (2005)<br></p>Fórmula:C9H18O2Cor e Forma:NeatPeso molecular:158.242-Chloronaphthalene-d7
CAS:Produto Controlado<p>Applications 2-Chloronaphthalene-d7 (CAS# 93951-84-9) is a useful isotopically labeled research compound.<br></p>Fórmula:C102H7ClCor e Forma:NeatPeso molecular:169.668-Oxo-2’-deoxyguanosine-13C,15N2
CAS:Produto Controlado<p>Applications A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro.<br>References Ueda, T., et al.: Chem. Pharm. Bull., 26, 2122 (1978), Jiang, F., et al.: Nature, 183, 382 (1996),<br></p>Fórmula:C913CH13N315N2O5Cor e Forma:NeatPeso molecular:286.22Nicergoline-d3
CAS:Produto Controlado<p>Applications Nicergoline-d3 is the labeled analogue of Nicergoline(N394550), a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia.<br>References Caraci, F., et. al.: Brain Res., 1047, 30 (2005); Mizuno, T., et. al.: Brain Res., 1066, 78 (2005)<br></p>Fórmula:C24D3H23BrN3O3Cor e Forma:NeatPeso molecular:487.4042-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzonic Acid
CAS:Produto Controlado<p>Applications 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzonic Acid is a potential metabolite of Chlorthalidone.<br>References Salado C., et al.: J. Chromatography. Biomed. App., 690, 195 (1997);<br></p>Fórmula:C14H10ClNO5SCor e Forma:NeatPeso molecular:339.75Methyl Benzilate
CAS:Produto Controlado<p>Applications Methyl Benzilate is a reactant in the synthesis of Trimethadione (T796155), an anticonvulsant and antiepileptic agent used in the treatment of pregnant women. Prenatal exposure to snti-epileptic drugs (AEDs) has indicated increased risk of major or minor congenital malformation.<br>References Pastore, V., et. al.: Bioorg. Med. Chem., 21, 841 (2013); Ahir, B. et al.: Toxicol. Vitro., 28, 948 (2014); Pastore, V. et al.: Bioorg. Med. Chem., 21, 841 (2013)<br></p>Fórmula:C15H14O3Cor e Forma:Off White PowderPeso molecular:242.27L-Asparagine-13C4, 15N2 Hydrate
CAS:Produto ControladoFórmula:C4H815N2O3H2OCor e Forma:NeatPeso molecular:138.081802Bilirubin (>90%)
CAS:Produto Controlado<p>Applications Principal pigment of bile and constituent of many biliary calculi.<br>References Stenhagen, R., et al.: Biochem. J., 33, 1591 (1939), Gray, et al.: J. Chem. Soc., 2264, 2268 (1961),<br></p>Fórmula:C33H36N4O6Pureza:>90%Cor e Forma:NeatPeso molecular:584.662(3R,5R)-Rosuvastatin Sodium Salt
CAS:<p>Impurity Rosuvastatin EP Impurity B<br>Stability Hygroscopic<br>Applications A diastereomer of Rosuvastatin (R700500) used for treatment, prevention and combination therapy of lipid-related disorders. Rosuvastatin EP Impurity B<br></p>Fórmula:C22H27FN3NaO6SCor e Forma:White To Light YellowPeso molecular:503.524'-Bromo-2,2':6',2''-terpyridine
CAS:Produto Controlado<p>Applications 4'-Bromo-2,2':6',2''-terpyridine (cas# 149817-62-9) is a useful research chemical.<br></p>Fórmula:C15H10BrN3Cor e Forma:NeatPeso molecular:312.16Hydroxy Dehydro Nifedipine Lactone
CAS:Produto ControladoFórmula:C16H12N2O6Cor e Forma:NeatPeso molecular:328.28Acetyl-1,2-13C2 Coenzyme A Sodium Salt (~2% Unlabelled)
CAS:Produto Controlado<p>Applications Acetyl-1,2-13C2 Coenzyme A Sodium Salt is a useful synthetic intermediate.<br></p>Fórmula:C2113C2H38N7O17P3S•x(Na)Cor e Forma:NeatPeso molecular:811.562299Sodium 2,2'-Methylene-bis(4,6-di-tert-butylphenyl)phosphate
CAS:Produto Controlado<p>Applications Sodium 2,2'-Methylene-bis(4,6-di-tert-butylphenyl)phosphate is an organophosphate nucleating agent.<br>References Li, J., et al.: Suliao, 43, 47-50 (2014);<br></p>Fórmula:C29H42O4P·NaCor e Forma:White PowderPeso molecular:508.604'-hydroxy-3',5'-diiodo-[1,1'-Biphenyl]-4-carbonitrile
CAS:Produto Controlado<p>Applications 4'-hydroxy-3',5'-diiodo-[1,1'-Biphenyl]-4-carbonitrile is a useful building block compound, and has been used in the preparation of plasminogen activator inhibitor antagonists.<br>References Madison, E. L.; et al.: US 6677473 (2004).<br></p>Fórmula:C13H7I2NOCor e Forma:NeatPeso molecular:447.01Mefruside
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Mefruside is a diuretic used for the treatment of edema and hypertension.<br>References Johansen, A., et al.: Euro. J. Epidemiol., 27, 63 (2012); Hasegawa, Y., et al.: Blood. Press. Supple., 1, 10 (2010);<br></p>Fórmula:C13H19ClN2O5S2Cor e Forma:Off-WhitePeso molecular:382.886β-Hydroxy Norethindrone Acetate
CAS:Produto Controlado<p>Impurity Norethindrone Acetate EP Impurity F<br>Applications 6β-Hydroxy Norethindrone Acetate (Norethindrone Acetate EP Impurity F) is an oxidative product of the drug Norethindrone (N676000). Norethindrone impurity.<br>References Reif, V., et al.: Pharmaceutical Res., 4, 54 (1987), Rao, P., et al.: Steroids, 59, 621 (1994),<br></p>Fórmula:C22H28O4Cor e Forma:Off-WhitePeso molecular:356.46Isoxanthopterin
CAS:Produto Controlado<p>Applications Isoxanthopterin is a metabolite found in brown rice.<br>References Wang, C., et al.: J. Sci. Food Agric., 100, 4364 (2020)<br></p>Fórmula:C6H5N5O2Cor e Forma:NeatPeso molecular:179.144-(4-Nitrophenyl)-3-morpholinone
CAS:Produto ControladoFórmula:C10H10N2O4Cor e Forma:NeatPeso molecular:222.20(±)-α-Fenchol
CAS:<p>Applications (±)-α-Fenchol is found in essential oils from many plants. It has been studied for, insecticidal activity of essential oil from Helichrysum faradifani; antioxidant and antibacterial activity of essential oils from rhizome, leaf and stem of Etlingera sayapensis against growth of Bacillus subtilis, Escherichia coli and Candida albicans.<br>References Benelli G., et al., Nat. Prod. Res., 32, 690-1698 (2018); Mahdavi B., et al., Asian. Pac. J. Trop. Med., 10, 819-826 (2017)<br></p>Fórmula:C10H18OCor e Forma:NeatPeso molecular:154.251-Acenaphthenone
CAS:<p>Applications 1-Acenaphthenone is a product of the photolysis (and microbial metabolism) of acenaphthene, a polycyclic hydrocarbon that has potential to act as polyploidizing agents in plants.<br>References Kostoff, D.: Nature, 142, 753 (1938); Reyes, C., et al.: J. Photochem. Photobio. A, 112, 277 (1998); Schocken, M. & Gibson, D.: Appl. Environ. Microb., 48, 10 (1984)<br></p>Fórmula:C12H8OCor e Forma:NeatPeso molecular:168.19(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinecarboxylic Acid Phenylmethyl Ester
CAS:Produto ControladoFórmula:C30H28N6O3Cor e Forma:NeatPeso molecular:520.582(2-Nitrophenyl)phosphoric Triamide
CAS:Produto Controlado<p>Applications (2-Nitrophenyl)phosphoric triamide is used in the preparation of N-phenylphosphoric acid triamides derivatives as agents for regulating or inhibiting enzymatic urea hydrolysis.<br>References Benini, S., et al.: Eur. J. Biochem., 239, 61 (1996), Witte, C., et al.: Plant Physiol., 128, 1129 (2002), Krajewska, B., rt al.: Bioorg. Chem. 35, 355 (2007),<br></p>Fórmula:C6H9N4O3PCor e Forma:Yellow CrystallinePeso molecular:216.134-Nitrophenol Sodium Salt Dihydrate
CAS:Produto ControladoFórmula:C6H4NNaO3·2(H2O)Cor e Forma:NeatPeso molecular:161.09 + 2(18.02)Xanthurenic Acid-d4
CAS:Produto Controlado<p>Applications Labelled Xanthurenic Acid (X743500). Excreted by pyridoxine-deficient animals after the ingestion of tryptophan.<br>References Aquilina, J., et al.: Biochemistry, 39, 16176 (2000), Roberts, J., et al.: Photochem. Photobiol., 74, 740 (2001),<br></p>Fórmula:C102H4H3NO4Cor e Forma:NeatPeso molecular:209.19Androstenediol 3-Acetate
CAS:Produto Controlado<p>Applications Androstenediol 3-Acetate is an intermediate in the synthesis of Pregnenolone (P712200) which is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens.<br>References Stastna, E., et al.: Steroids., 75, 721 (2010);<br></p>Fórmula:C21H32O3Cor e Forma:NeatPeso molecular:332.48Sorafenib Tosylate
CAS:Produto ControladoFórmula:C21H16ClF3N4O3·C7H8O3SCor e Forma:NeatPeso molecular:637.03(2-Nitrophenyl)hydrazine (Contains ~30-40% water as stabilizer)
CAS:<p>Applications (2-Nitrophenyl)hydrazine (cas# 3034-19-3) is a useful research chemical.<br></p>Fórmula:C6H7N3O2Cor e Forma:NeatPeso molecular:153.146-Methyl-1,4-naphthoquinone
CAS:Produto Controlado<p>Applications 6-Methyl-1,4-naphthoquinone (cas# 605-93-6) is a compound useful in organic synthesis.<br></p>Fórmula:C11H8O2Cor e Forma:NeatPeso molecular:172.187-Methoxy-3,4-dihydro-1-naphthalenyl-acetonitrile
CAS:Produto Controlado<p>Applications 7-Methoxy-3,4-dihydro-1-naphthalenyl-acetonitrile (cas# 861960-34-1) is a compound useful in organic synthesis.<br></p>Fórmula:C13H13NOCor e Forma:NeatPeso molecular:199.254-Nitrophenethyl Bromide
CAS:Produto ControladoFórmula:C8H8BrNO2Cor e Forma:Off White To Light YellowPeso molecular:230.061,3-Dimethylnaphthalene
CAS:Produto ControladoFórmula:C12H12Cor e Forma:ColourlessPeso molecular:156.22Sodium Chlorite (Technical Grade)
CAS:<p>Applications Sodium Chlorite is used as a bleaching agent for cotton textiles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shenai, V.A., Pai, S.M.: Textile Dyer Printer, 3, 153 (1969)<br></p>Fórmula:ClO2·NaCor e Forma:NeatPeso molecular:90.4416
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