Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(273.774 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.606 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.613 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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Dihydro Ferulic Acid Methyl Ester
CAS:Produto Controlado<p>Applications A protected caffeine metabolite with high antioxidant activity. It is a very sensitive biomarker for the consumption of relatively small amount of coffee.<br>References Buchanan, C., et al.: J. Sci. Food Agric., 71, 459 (1996), Andreasen, M., et al.: J. Agric. Food Chem., 49, 5679 (2001), Poquet, L., et al.: Drug Metab. Dispos., 36, 190 (2008),<br></p>Fórmula:C11H14O4Cor e Forma:NeatPeso molecular:210.235-Hydroxycytosine
CAS:Produto Controlado<p>Applications 5-Hydroxycytosine, is been identified as an anomalous base of phage H-17 DNA. It is also a monosubstituted cytosine, as nucleotide-base antimetabolite-type potential anticarcinogen.<br>References Khromov, I. S. Doklady Akademii Nauk SSSR, 240, 1486 (1978); Ladik, J., et al.: Magyar Kemiai Folyoirat, 76, 589 (1970);<br></p>Fórmula:C4H5N3O2Cor e Forma:NeatPeso molecular:127.10Calcium Chloride Hydrate
CAS:<p>Applications Calcium Chloride Dihydrate is used in the preparation of bisphosphonates used in attacking cancer cells.<br>References Liu, D. et al.: Chem. Comm., 48, 2668 (2012);<br></p>Fórmula:Ca·2Cl·2H2OCor e Forma:NeatPeso molecular:147.011-Fluoronaphthalene
CAS:<p>Impurity Duloxetine EP Impurity G<br>Applications 1-Fluoronaphthalene (Duloxetine EP Impurity G) is a fluorinated naphthalene derivative that is metabolized by fungal monooxygenase-epoxide hydrolase. Duloxetine (D721000) impurity.<br>References Cerniglia, C.E. et al.: Appl. Env. Microbiol., 48, 294 (1984);<br></p>Fórmula:C10H7FCor e Forma:Light Yellow LiquidPeso molecular:146.16Isovaleryl L-Carnitine-d9 Chloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Isovaleryl L-Carnitine-d9 Chloride is labelled Isovaleryl L-Carnitine Chloride (I917580) which is used to prepare carnitine benzyl esters as neuroprotectant prodrugs.<br>References Gong, X., et al.: J. Chem. Res., 6, 327 (2008)<br></p>Fórmula:C12H15D9ClNO4Cor e Forma:NeatPeso molecular:290.833-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt
CAS:Produto Controlado<p>Applications 3-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt is deuterium labeled 3-Cysteinylacetaminophen Trifluoroacetic Acid Salt (C994750), which is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).Minimum isotopic incorporation d-3, no d-0 present. A representative lot has 64% isotopic incorporation at the 6-position, 89% at the 4-position.<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C11H9D5N2O4S•C2HF3O2Cor e Forma:NeatPeso molecular:389.361,2,4-Trioctyl Ester 1,2,4-Benzenetricarboxylic Acid-d51
CAS:Produto Controlado<p>Applications Isotope labelled 1,2,4-Trioctyl Ester 1,2,4-Benzenetricarboxylic Acid is a widely used and often incorporated in plasticizer for PVC for a higher molecular weight.<br>References Jones, C., et al.: Int. J. Artificial. Organs., 12, 466 (1989); Khang, G., et al.: Bio-Med. Mater. Engineer., 12, 135 (2002);<br></p>Fórmula:C33D51H3O6Cor e Forma:NeatPeso molecular:598.092Methyl-(4-nitrophenylethyl)-(4-nitrophenoxyethyl)amine
CAS:Produto Controlado<p>Applications Methyl-(4-nitrophenylethyl)-(4-nitrophenoxyethyl)amine (cas# 115287-37-1) is a compound useful in organic synthesis.<br></p>Fórmula:C17H19N3O5Cor e Forma:NeatPeso molecular:345.352,5-Dinitrophenol (Wetted with water >15%)
CAS:Produto Controlado<p>Applications 2,5-Dinitrophenol (wetted with ca. 20% Water) (unit weight on dry weight basis) is a useful reagent for the preparation of yttrium nitrophenolate aminebis(benzotriazolylphenolate) complexes.<br> E0<br>References Su, Y. C., et al.: J. Polym. Sci. A Polym. Chem., 57, 2038 (2019)<br></p>Fórmula:C6H4N2O5Cor e Forma:NeatPeso molecular:184.11O,O-Dimethyl Dithiophosphate-13C2 Ammonium salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled dimethyl phosphorodithiolate derivatives used as insecticides.<br></p>Fórmula:C2H10NO2PS2Cor e Forma:Off-WhitePeso molecular:177.20Hydroxy Urea-13C,15N2
CAS:Produto Controlado<p>Applications Labelled Hydroxyurea. An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.<br>References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),<br></p>Fórmula:CH4N2O2Cor e Forma:Off White SolidPeso molecular:79.03α-Citral
CAS:<p>Applications α-Citral is an intermediate in the synthesis of 4,8-Dimethyl-1,3(E),7-nonatriene (D475810), which is a volatile compound released by corn plants in response to predation.<br>References Alborn, H,T,. et al.: Science, 276, 945 (1997)<br></p>Fórmula:C10H16OCor e Forma:Colourless To Light YellowPeso molecular:152.244,4'-Di-tert-butyl-2,2'-bipyridine
CAS:Produto Controlado<p>Applications 4,4'-Di-tert-butyl-2,2'-bipyridine acts as a reagent in the preparation, antiproliferative and cytotoxic activity of apoptotic ruthenium nitrogen heterocyclic complexes via combinatorial library synthesis.<br>References Mulcahy, S. P., et al.: Dalton Trans., 39, 177 (2010)<br></p>Fórmula:C18H24N2Cor e Forma:NeatPeso molecular:268.41-Naphthoyl Chloride
CAS:<p>Applications 1-Naphthoyl Chloride acts as a reagent in the preparation of tetrandrine derivatives as antitumor agents against human hepatocellular carcinoma. Identification of acylthiourea derivatives as potent Plk1 PBD inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lan, J., et al.: Eur. J. Med. Chem., 127, 554 (2017); Yun, T., et al.: Eur. J. Med. Chem., 124, 229 (2016)<br></p>Fórmula:C11H7ClOCor e Forma:NeatPeso molecular:190.633'-Azido-3'-deoxythymidine-methyl-d3 β-D-glucuronide, Sodium Salt
CAS:Produto Controlado<p>Applications A deuterated metabolite of the potent and selective inhibitor of HIV-1 replication, AZT.This compounds contains Sodium Chloride. Water content not determined.<br></p>Fórmula:C16D3H17N5O10·NaCor e Forma:NeatPeso molecular:468.36583-(3-Amino-4-methylphenyl)-5-isopropylimidazolidine-2,4-dione
Produto ControladoFórmula:C13H17N3O2Cor e Forma:NeatPeso molecular:247.31-Naphthoic Acid-d7
CAS:Produto Controlado<p>Applications 1-Naphthoic Acid-d7 (cas# 634179-80-9) is a compound useful in organic synthesis.<br></p>Fórmula:C112H7HO2Cor e Forma:NeatPeso molecular:179.224-Hydroxy-2-oxovaleric Acid Potassium Salt (>90%)
CAS:Produto Controlado<p>Applications 4-Hydroxy-2-oxovaleric acid potassium salt is converted from pyrocatechol metabolism by Pseudomonas.<br>References Dagley, S., et al.: J. Biol. Chem., 239, PC1284 (1964);<br></p>Fórmula:C5H7KO4Pureza:>90%Cor e Forma:NeatPeso molecular:170.2051,2-Diaminonaphthalene
CAS:Produto Controlado<p>Applications Reacts with aldehydes to produce highly fluorescent imidazole derivatives. A fluorometric labeling reagent. It is used for fluorophotometric determination of selenium in some kinds of mushroom.<br>References Lehmann, S., et al.: J. Biol. Chem., 272, 21479 (1997), Ragg, E., et al.: Eur. J. Biochem., 266, 1192 (1999), Tagliavini, F., et al.: J. Mol. Biol., 300, 1309 (2000),<br></p>Fórmula:C10H10N2Cor e Forma:NeatPeso molecular:158.209-(N-Methylaminomethyl)anthracene
CAS:Produto Controlado<p>Applications 9-(N-Methylaminomethyl)anthracene is a reactant that has been used in the synthesis of anthracene-oxyquinoline dyad as a fluorescent indicator for Hg(II).<br>References Praveen, L., et. al.: Tetrahedron Lett., 53, 3951 (2012)<br></p>Fórmula:C16H15NCor e Forma:NeatPeso molecular:221.33-Hydroxyglutaric Acid-d5
CAS:Produto ControladoFórmula:C5H3D5O5Cor e Forma:NeatPeso molecular:153.14Urolithin A
CAS:<p>Applications Urolithin A is a major metabolite of ellagitannin and exhibits anti-inflammatory and antioxidant properties.<br>References Ishimoto, H., et. al.: Bioorg. Med. Chem. Lett., 21, 5901 (2011);<br></p>Fórmula:C13H8O4Cor e Forma:NeatPeso molecular:228.20Dihydro Isoferulic Acid-d3 3-O-β-D-Glucuronide
CAS:Produto Controlado<p>Applications Labelled Dihydroisoferulic Acid 3-O-β-D-Glucuronide, the glucuronide conjugate of Dihydroisoferulic Acid (H946365). Dihydroisoferulic Acid 3-O-β-D-Glucuronide is a minor circulating metabolite in human plasma after ingestion of coffee and can be used as a biomarker of coffee consumption.<br>References Fumeaux, R. et al.: Org. Biomol. Chem., 8, 5199 (2010); Stalmach, A. et al.: Drug Metab. Disp., 37, 1749 (2009);<br></p>Fórmula:C16H17D3O10Cor e Forma:NeatPeso molecular:375.34Ethyl 2-Bromoisovalerate
CAS:<p>Applications Ethyl 2-Bromoisovalerate (cas# 609-12-1) is a compound useful in organic synthesis.<br></p>Fórmula:C7H13BrO2Cor e Forma:NeatPeso molecular:209.08ethyl (4-nitrophenyl)carbamate
CAS:Produto Controlado<p>Applications ethyl (4-nitrophenyl)carbamate (cas# 2621-73-0) is a useful research chemical.<br></p>Fórmula:C9H10N2O4Cor e Forma:NeatPeso molecular:210.181-Naphthalenemethanol-d7
CAS:Produto Controlado<p>Applications 1-Naphthalenemethanol-d7 (cas# 1189876-86-5) is a compound useful in organic synthesis.<br></p>Fórmula:C11H3D7OCor e Forma:Light BrownPeso molecular:165.24D-(+)-Carvone
CAS:<p>Applications D-(+)-Carvone, is used for the synthesis of (-)-terpestacin, a fungal metabolite with anticancer activity.It is also found in the essential oils of the in vitro M. longifolia plantlets and callus, that can be used as a potential source of a safe flavouring agent.<br>References Jin , Y., et al.: Org. Biomol. Chem., 10(28), 5452 (12012); Morcia, C., et al.: Acta. Biochimica. Polonica., 58(4), 581 (2011);<br></p>Fórmula:C10H14OCor e Forma:NeatPeso molecular:150.222'-Deoxyadenosine-15N1
CAS:Produto Controlado<p>Applications 2'-Deoxyadenosine-15N1 is an intermediate in the synthesis of 8-Oxo-2’-deoxyguanosine-13C,15N2 (O850252). A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro.<br>References Ueda, T., et al.: Chem. Pharm. Bull., 26, 2122 (1978), Jiang, F., et al.: Nature, 183, 382 (1996),<br></p>Fórmula:C10H1315NN4O3Cor e Forma:NeatPeso molecular:252.2357-Nitrocoumarin
CAS:Produto Controlado<p>Applications Coumarin derivatives were made for trial as bacteriostats.<br></p>Fórmula:C9H5NO4Cor e Forma:NeatPeso molecular:191.142'-Hydroxyflavone
CAS:Produto Controlado<p>Applications 2'-Hydroxyflavone (cas# 35244-11-2) is a useful research chemical.<br></p>Fórmula:C15H10O3Cor e Forma:NeatPeso molecular:238.238Valeric Acid-d9
CAS:Produto Controlado<p>Applications Valeric Acid-d9 is the isotope labelled analog of Valeric Acid which is used in biological studies of (D)-β-hydroxybutyrate which inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Taggart, A.K.P., et al.: J. Bio. Chem., 280, 26649 (2005);<br></p>Fórmula:C5D9HO2Cor e Forma:NeatPeso molecular:111.19Triacetin-d9
CAS:Produto Controlado<p>Applications Triacetin-d5 is the isotope labelled analog of Triacetin (T720850); a compound used as a food additive and flavoring. Triacetin can be used as an excipient in pharmaceutical products where it is used as a humectant, a plasticizer, and as a solvent. Triacetin can also be used as a fuel additive as an antiknock agent.<br>References Mouret, A., et al.: Green Chem., 16 (1), 269 (2014); Snejdrova, E., et al.: Inter. J. Pharma., 458, 282 (2013)<br></p>Fórmula:C9D9H5O6Cor e Forma:NeatPeso molecular:227.264-Nitrophenol-1,2,6-13C3
CAS:Produto Controlado<p>Applications Labelled 4-Nitrophenol (N496945). Used in the manufacturing of pharmaceuticals, fungicides, dyes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C6H7NO3Cor e Forma:NeatPeso molecular:147.08Guanyl Urea Sulfate
CAS:<p>Applications It is used for detecting and determining Ni and its separation from Co and other metals.<br>References Jacob, K.D., et al.: J. Agric. Res., 28, 37 (1924),<br></p>Fórmula:C2H6N4O·H2O4SCor e Forma:NeatPeso molecular:302.27(-)-β-Sesquiphellandrene
CAS:Produto Controlado<p>Applications (-)-β-Sesquiphellandrene are found in Tanacetum vulgare plants. It is also an essential leaf and flower oils in Heracleum species.<br>References Clancy, M. V., et al.: Sci. Rep., 6, 38087 (2016); Usjak, L., et al.: Food Funct., 8, 278-290 (2017);<br></p>Fórmula:C15H24Cor e Forma:ColourlessPeso molecular:204.352-Aminoanthracene
CAS:Produto Controlado<p>Stability Air Sensitive<br>Applications 2-AMINOANTHRACENE (cas# 613-13-8) is a useful research chemical.<br></p>Fórmula:C14H11NCor e Forma:NeatPeso molecular:193.24Allantoic Acid
CAS:Produto Controlado<p>Applications A metabolic intermediate in nucleic acid metabolism.<br>References Yoon, K., et al.: Nat. Prod. Sci., 14, 254 (2008), Ramazzina, I., et al.: J. Biol. Chem., 283, 23295 (2008), Kim, K., et al.: J. Mol. Biol., 387, 1067 (2009),<br></p>Fórmula:C4H8N4O4Cor e Forma:White To Off-WhitePeso molecular:176.13(Benzyl-d5)decyldimethylammonium Chloride
CAS:Produto Controlado<p>Applications (Benzy-d5)ldecyldimethylammonium Chloride is labelled Benzyldecyldimethylammonium Chloride (B234550) which is a biocide.<br>References Lee, M., et al.: Appl. Micro. Biotech., 87, 1109 (2010); Campanac, C., et al.: Antimicrob. Agents Ch., 46, 1469 (2002); Shen, J., et al.: Anal. Chem., 62, 116 (1990)<br></p>Fórmula:C19H29D5ClNCor e Forma:NeatPeso molecular:316.962'-Chloroacetophenone
CAS:Produto Controlado<p>Applications 2'-Chloroacetophenone (cas# 2142-68-9) is a compound useful in organic synthesis.<br></p>Fórmula:C8H7ClOCor e Forma:NeatPeso molecular:154.592'-Hydroxybiphenyl-3-carboxylic Acid
CAS:<p>Applications 2'-Hydroxybiphenyl-3-carboxylic acid<br></p>Fórmula:C13H10O3Cor e Forma:NeatPeso molecular:214.22Pyruvic Acid-2-13C Sodium Salt
CAS:Produto Controlado<p>Applications Labelled Pyruvic acid (P998900). Intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscle, Pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion, which is reoxidized and partially retransformed to glycogen during rest. The liver can convert Pyruvic acid to alanine by amination. A diagnostic agent for Parkinson disease.<br>References Wenzel, A., et al.: J. Neurosci., 21, 53 (2001), Martinez., et al.: Development, 6, 851 (2002), Nakayama, K., et al.: J. Biochem., 146, 757 (2009), Tanaka, T., et al.: J. Pharmacol. Sci., 109, 24 (2009),<br></p>Fórmula:C213CH3NaO3Cor e Forma:NeatPeso molecular:111.04N-Nitroso Nipecotic Acid-d4 (Major)
CAS:Produto Controlado<p>Applications A major urinary labelled metabolite of N-nitrosoguvacoline (N527625) and N-nitrosoguvacine, found in cigarette tobacco.<br>References Ernst, H., et al.: Carcinogenesis, 8, 1843 (1987),<br></p>Fórmula:C6H6D4N2O3Cor e Forma:Off-White To BeigePeso molecular:162.18Polygalacturonic Acid (Technical Grade)
CAS:Produto Controlado<p>Applications Polygalacturonic Acid is found in ripe fruits and some vegetables and is a degradation product of pectin in plants.<br>References Aspinall, G., et al.: J. Chem. Soc., 4020 (1958);<br></p>Fórmula:(C6H10O7)nCor e Forma:NeatPeso molecular:194.14Salbutamol Glyoxal Impurity
Produto Controlado<p>Stability Hygroscopic<br>Applications Salbutamol Glyoxal Impurity that is synthesized from C369215 (3-Chloromethyl-4-hydroxyacetophenone).<br></p>Fórmula:C9H10O5Cor e Forma:Off White SolidPeso molecular:198.179,10-Dibromoanthracene-2-sulfonic Acid Sodium Salt
CAS:Produto Controlado<p>Applications 9,10-Dibromoanthracene-2-sulfonic Acid Sodium Salt (cas# 87796-18-7) is a compound useful in organic synthesis.<br></p>Fórmula:C14H7Br2O3S·NaCor e Forma:NeatPeso molecular:438.07Hexadecyl Acetate
CAS:Produto Controlado<p>Applications Hexadecyl Acetate is a plant sex pheromone.<br>References Brasero, N., et al.: J. Chem. Ecol., 44, 9 (2018); Cuervo, M., et al.: J. Chem. Ecol., 43, 469 (2017)<br></p>Fórmula:C18H36O2Cor e Forma:NeatPeso molecular:284.48Naphthalene-1-sulfonic Acid (Technical Grade)
CAS:Produto Controlado<p>Applications Naphthalene-1-sulfonic acid (cas# 85-47-2) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C10H8O3SCor e Forma:NeatPeso molecular:208.231, N6-Etheno-2'-deoxyadenosine-13C5
Produto Controlado<p>Applications 1, N6-Etheno-2’-deoxyadenosine-13C5 is caused by exposure to pollutants. It is an isotopically labeled analog of the 2’-Deoxyguanosine adduct.<br></p>Fórmula:C713C5H13N5O3Cor e Forma:NeatPeso molecular:280.234-(Methoxy-d3)-α-methyl-benzeneethanamine Hydrochloride
CAS:Produto Controlado<p>Applications 4-(Methoxy-d3)-α-methyl-(αS)-benzeneethanamine Hydrochloride is the labelled form of 4-Methoxyamphetamine Hydrochloride (M261015), which is the HCl salt of 4-Methoxyamphetamine. 4-Methoxyamphetamine is a designer drug belonging to the amphetamine class and releases 5-hydroxytryptamine in brain tissue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Menon, M., et al.: J. Pharmacol. Exp. Ther., 197, 272 (1976);<br></p>Fórmula:C10H12D3NO·HClCor e Forma:Off-WhitePeso molecular:204.714-Bromobenzoic Acid Methyl Ester
CAS:<p>Applications 4-Bromobenzoic Acid Methyl Ester is halogenated benzoate used as a reagent in organic synthesis. 4-Bromobenzoic Acid Methyl Ester can be used to stimulate microbial dechlorination of PCBs. 4-Bromobenzoic Acid Methyl Ester is also used in the preparation of stable radioiodinating reagent to label monoclonal antibodies for radiotherapy of cancer.<br>References Wilbur, D.S. et al.: J. Nuclear Med., 30, 216 (1989); DeWeerd, K.A. et al.: Environ. Sci. Technol., 33, 2057 (1999);<br></p>Fórmula:C8H7BrO2Cor e Forma:Off-WhitePeso molecular:215.04
