Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(273.774 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.606 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.613 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
α-Hederin
CAS:<p>Stability Hygrscopic<br>Applications α-Hederin is a saponin of dry extracts from the leaves of Hedera helix L.Inhibitor of β2-adrenergic receptor-GFP fusion proteins. Potential cause for asphyxiation.<br>References Sieben A. et al.: Biochem., 21, 3477 (2009); Gaillard, Y. et al.: J. Anal Toxicol., 27, 257 (2003);<br></p>Fórmula:C41H66O12Cor e Forma:NeatPeso molecular:750.965-Oxorosuvastatin Methyl Ester
CAS:<p>Applications 5-Oxorosuvastatin methyl ester is an intermediate in the synthesis of Rosuvasatatin (calcium salt: R700500), a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that decreases high-sensitivity C-reactive protein (hsCRP) and cholesterol concentrations in the blood.<br>References McTaggart, F., et al.: Am. J. Cardiol., 87, 28 (2001); Ridker, P., et al.: Lancet, 373, 1175 (2009)<br></p>Fórmula:C23H28FN3O6SCor e Forma:Yellow SolidPeso molecular:493.55Ciprofibrate Ethyl Ester
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Ciprofibrate Ethyl Ester is an impurity of ciprofibrate(C482475) is a hypolipemic agent, related structurally to Clofibrate (C586910). Ciprofibrate is used as an antilipemic.<br>References Davison, C., et al.: Drug. Metab. Dispos., 3, 520 (1975), Arnold, A., et al.: J. Pharm. Sci., et al.: 68, 1557 (1979), Tuchman-Duplessis, H., et al.: Toxicology, 12, 1 (1979),<br></p>Fórmula:C15H18Cl2O3Cor e Forma:Colourless To Off-WhitePeso molecular:317.2119-Norandrosterone
CAS:Produto Controlado<p>Applications 19-Norandrosterone is the oxidized byproduct of Nandrolone (N315000), an anabolic steroid that is present naturally in the human body.<br>References Jiang, J.Q., et al.: J. Food. Sci., 77, 63 (2012); Delgadillo, M.A., et al.: J. Chromatograph. Anal. Technol. Biomed. Life. Sci., 897 (2012);<br></p>Fórmula:C18H28O2Cor e Forma:NeatPeso molecular:276.41Atorvastatin Ethyl Ester
CAS:Produto Controlado<p>Applications Atorvastatin (A791750) impurity.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996);<br></p>Fórmula:C35H39FN2O5Cor e Forma:Off White SolidPeso molecular:586.694-Methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic Acid
CAS:Produto Controlado<p>Applications 4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic acid (cas# 144059-86-9) is a useful research chemical.<br></p>Fórmula:C12H8F3NO2SCor e Forma:NeatPeso molecular:287.26Rosuvastatin Triphenylphosphonium Bromide
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications An intermediate in the production of Rosuvastatin (R700500) derivatives.<br></p>Fórmula:C34H34FN3O2PS·BrCor e Forma:WhitePeso molecular:678.596β-Hydroxy-21-desacetyl Deflazacort
CAS:<p>Applications The major metabolite of Deflazacort.<br>References Bernareggi, A., et al.: J. Pharma. Biomed. Anal., 5, 177-81 (1987), Assandri, A., et al.: Xenobiotica, 13(3), 185 (1983), Martinelli, E., et al.: Drug Metab. Dispos., 7, 335 (1979),<br></p>Fórmula:C23H29NO6Cor e Forma:NeatPeso molecular:415.48Digoxigenin Monodigitoxoside
CAS:Produto Controlado<p>Applications A metabolite of Digoxin (Dx) (D446575).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujii, Y., et al.: Clin. Chem., 37, 476 (1991), Salphati, L., et al.: Xenobiotica, 29, 171 (1999), Song, S., et al.: Drug Metab. Dispos., 27, 689 (1999),<br></p>Fórmula:C29H44O8Cor e Forma:BeigePeso molecular:520.65Droxicam
CAS:Produto Controlado<p>Applications Droxicam is a non-steroidal anti-inflammatory drug.<br>References Lapeyre-Mestre, M., et. al.: Fundam. Clin. Pharm., 20, 391 (2006)<br></p>Fórmula:C16H11N3O5SCor e Forma:Off-White To Light YellowPeso molecular:357.34Edoxaban Tosylate Monohydrate
CAS:<p>Applications Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor.<br>References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)<br></p>Fórmula:C31H38ClN7O7S2•xH2OCor e Forma:White To Off-WhitePeso molecular:720.26Naphthacene
CAS:Produto Controlado<p>Applications Naphthacene is a polycyclic aromatic hydrocarbon. Naphthacene is often used as a molecular organic semiconductor in organic field-effect transistors and organic light-emitting diodes. Naphthacene is also used in various applications involving the enhancement of photocurrent.<br>References Cnops, K., et al.: Applied. Phy. Letters., 101, 143301 (2012); Ooi, Z.E., Applied. Phy. Letters., 100, 93302 (2012);<br></p>Fórmula:C18H12Pureza:>80%Cor e Forma:NeatPeso molecular:228.292,6-Dimethyl-4-nitrophenol
CAS:Produto Controlado<p>Applications 2,6-Dimethyl-4-nitrophenol is a useful compound for the production and characterization of bio-oil from hardwood and softwood lignin.<br>References Zadeh, Z. E., et al.: Energies (Basel, Switzerland), 13, 887 (2020)<br></p>Fórmula:C8H9NO3Cor e Forma:NeatPeso molecular:167.162Norketamine-d4 (1 mg/ml in Acetonitrile)
CAS:Produto ControladoFórmula:C12H10D4ClNOCor e Forma:Colourless To Light YellowPeso molecular:227.72Thiourea-13C
CAS:Produto Controlado<p>Applications Thiourea-13C is an isotope labelled version of Thiourea (T375450). Hyperpolarized Thiourea-13C is used as an analyte in the real-time in vivo detection of hydrogen peroxide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wibowo, Arif, et al.: ACS Chem. Bio., 12(7), 1737-1742 (2017)<br></p>Fórmula:CH4N2SCor e Forma:NeatPeso molecular:77.116α-Methyl-9α-fluoro-11β,17α-dihydroxyprogesterone
CAS:Produto Controlado<p>Applications 6α-Methyl-9α-fluoro-11β,17α-dihydroxyprogesterone is an impurity of Fluorometholone (F593145), a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982), Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984),<br></p>Fórmula:C22H31FO4Cor e Forma:NeatPeso molecular:378.48Potassium Bromide
CAS:<p>Applications Potassium bromide is an ionic compound that is commonly used in chemistry to form a pellet that can be used to analyze a number of compounds by means of infrared spectroscopy. Potassium bromide is also used as an anticonvulsant to treat refractory seizures in humans and dogs.<br>References Kirkland, J.: Anal. Chem., 27, 1537 (1955); Korinthenberg, R., et al.: J. Child Neuro., 22, 414 (2007); Wilberley, S., et al.: Anal. Chem., 29, 210 (1957); Yohn, S., et al.: J. Am. Vet. Med. Ass., 201, 468 (1992)<br></p>Fórmula:BrKCor e Forma:White To Off-WhitePeso molecular:119.00Finasteride Carboxylic Acid
CAS:Produto ControladoFórmula:C23H34N2O4Cor e Forma:Light Yellow SolidPeso molecular:402.53Dicobalt Edetate (>90%)
CAS:Produto Controlado<p>Applications Dicobalt Edetate is used as a cyanide antidote.<br>References Hall, A.H., et. al.: Crit. Rev. Toxicol., 39, 541 (2009); Higgins, M.A., Evans, R.: Hum. Exp. Toxicol., 19, 485 (2000); Krovzov, J., et. al.: P. W. Pharmacol. Soc., 37, 43 (1994)<br></p>Fórmula:C10H12Co2N2O8Pureza:>90%Cor e Forma:NeatPeso molecular:406.08apo-Ipratropium Bromide
CAS:<p>Applications apo-Ipratropium Bromide is an intermediate used in the preparation of quaternary salts of alkaloids.<br>References Ivanov, V., et al.: Farmatsiya17, 18 (1967)<br></p>Fórmula:C20H28NO2·BrCor e Forma:NeatPeso molecular:394.346a-Chloro Testosterone
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications 6α-Chloro Testosterone is a derivative of Testosterone, the principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.Testerone is a controlled substance (anabolic steroid). Androgen.This compound is a contaminant of emerging concern (CECs).<br>References McFarland, K., et al.: Science, 245, 494 (1989), Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998), Themmen, A., et al.: Endocr. Rev. 21, 551 (2000), Kumar, R., et al.: Biol. Reprod., 65, 710 (2001),<br></p>Fórmula:C19H27ClO2Cor e Forma:NeatPeso molecular:322.87rac N-Bisdesmethyl Tramadol, Hydrochloride
CAS:<p>Applications A metabolite of Tramadol.<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Fórmula:C14H22ClNO2Cor e Forma:NeatPeso molecular:271.78all-trans-Retinol-d5, >80%
CAS:Produto ControladoFórmula:C20H25D5OPureza:>80%Cor e Forma:NeatPeso molecular:291.48(S)-(-)-Carvedilol
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications The optically active isomer of Carvedilol (C184625), a nonselective ß-adrenergic blocker with a1-blocking activity. An antihypertensive used in the treatment of congestive heart failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990),<br></p>Fórmula:C24H26N2O4Cor e Forma:Off White SolidPeso molecular:406.47Embramine Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Antihistaminic.<br>References Berthon, B., et al.: Biochem. Pharmacol., 47, 789 (1994), Hu, Q., et al.: J. Biol. Chem., 274, 33995 (1999),<br></p>Fórmula:C18H22BrNO·ClHCor e Forma:NeatPeso molecular:384.74N-Desmethyl (E)-α-Hydroxy Tamoxifen
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications N-Desmethyl (E)-α-Hydroxy Tamoxifen is a N-demethylated, α-Hydroxyated metabolite of Tamoxifen (T006000).<br>References Poon, G.K. et al.: Drug Metab.Dispos. 23,377 (1995); Teunissen, S.F. et al.: J. Pharmac. Biomed. Anal., 55, 518 (2011); Muerdter, T.E. et al.: Clin. Pharmacol. Therap., 89, 708 (2011);<br></p>Fórmula:C25H27NO2Cor e Forma:NeatPeso molecular:373.49Hydroxydehydro Nifedipine Carboxylate
CAS:Produto ControladoFórmula:C16H14N2O7Cor e Forma:NeatPeso molecular:346.29Elenolic Acid (>90%)
CAS:<p>Applications Elenolic Acid is an antiviral agent that inhibits reverse transcriptases, inhibited the growth of chicken embryo fibroblast cells as well as Escherichia coli and Bacillus subtilis strains.<br>References Heinze, J.E., et al.: Antimicrob. Agents Chemother., 8, 421 (1975); Renis, H,E..: Antimicrob. Agents Chemother., 8, 149 (1975)<br></p>Fórmula:C11H14O6Pureza:>90%Cor e Forma:NeatPeso molecular:242.23N,N'-Methylene Ambroxol Hydrochloride
CAS:Produto Controlado<p>Impurity Ambroxol EP Impurity B Hydrochloride<br>Stability Hygroscopic<br>Applications Ambroxol Cyclic Impurity is a metabolite as well as an impurity of the bronchosecretolytic drug, Ambroxol (A575900).<br>References Hammer, R. et al.: Arzneim.-Forsch., 28, 899 (1978); Nieder, M. et al.: HRC & CC, 9, 561 (1986); Huq, F. et al.: J. Pharmacol. Toxicol., 3, 147 (2008);<br></p>Fórmula:C14H18Br2N2O·ClHCor e Forma:White To Off-WhitePeso molecular:426.57ASM-DNT
CAS:<p>Applications N,N'-Di-2-naphthyl-1,4-phenylenediamine (cas# 93-46-9) is a useful research chemical.<br></p>Fórmula:C26H20N2Cor e Forma:NeatPeso molecular:360.4504Zinc Pentamethylenedithiocarbamate
CAS:<p>Applications Zinc pentamethylenedithiocarbamate (cas# 13878-54-1) is a useful research chemical.<br></p>Fórmula:C12H20N2S4ZnCor e Forma:NeatPeso molecular:385.945-Chlorovaleronitrile
CAS:Produto Controlado<p>Applications 5-Chlorovaleronitrile is used as a reagent in the synthesis of cyanoguanidine derivatives which exhibit dual histamine H1 and H2 receptor antagonist activity. Also used in the synthesis of purine derivatives which exhibit antimicrobial activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kinali-Demirci, S., et al.: Med. Chem. Res., no vol., no pp. (2014); Sadek, B., et al.: Molecules, 18, 14186 (2013)<br></p>Fórmula:C5H8ClNCor e Forma:NeatPeso molecular:117.58Torsemide-d7
CAS:Produto Controlado<p>Applications Labelled Torsemide (T548750). Used as a diuretic.<br>References Lesne, M., et al.: In. J. Clin. Pharmacol. Ther. Toxicol., 20, 382 (1982), Brater, D.C., et al.: Clin. Pharmacol. Ther., 42, 187 (1987),<br></p>Fórmula:C162H7H13N4O3SCor e Forma:NeatPeso molecular:355.46trans-Caffeic Acid
CAS:<p>Applications trans-Caffeic Acid is a useful synthetic intermediate. It was used as a reactant to synthesize N-caffeoylphenalkylamide derivatives as bacterial efflux pump inhibitors. It is also used to prepare caffeic acid phenethyl ester analogs with antitumor structures.<br>References Michalet, S., et al.: Bioorg. Med. Chem. Lett., 17, 1755 (2007); Nagaoka, T., et al.: Bioorg. Med. Chem., 10, 3351 (2002)<br></p>Fórmula:C9H8O4Cor e Forma:NeatPeso molecular:180.16Trestolone Acetate
CAS:Produto Controlado<p>Applications Trestolone acetate is a derivative of Trestolone (T719600), a synthetic androgen used as a potential hormonal male contraceptive method that induces a state of temporary infertility.<br>References Garcia-Becerra, R., et al.: Reproduction., 143, 211 (2012); Attardi, B.J., et al.: J. Steroid. Biochem. Molec. Biol., 122, 212 (2010)<br></p>Fórmula:C21H30O3Cor e Forma:NeatPeso molecular:330.461,3-Dimethyl 2-[4-(methoxycarbonyl)-2-nitrophenyl]propanedioate
CAS:<p>Applications 1,3-Dimethyl 2-[4-(methoxycarbonyl)-2-nitrophenyl]propanedioate<br></p>Fórmula:C13H13NO8Cor e Forma:NeatPeso molecular:311.24Trimethylurea
CAS:Produto Controlado<p>Applications Trimethylurea (cas# 632-14-4) is a useful research chemical.<br></p>Fórmula:C4H10N2OCor e Forma:NeatPeso molecular:102.14Copper Acetoarsenite (Technical Grade)
CAS:<p>Applications Copper Acetoarsenite has been used as a rodenticide and insecticide, and also as a pigment, despite its toxicity. It is also used as a blue colorant for fireworks.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gaines, T.: Toxicol. Appl. Pharm., 2, 88 (1960); Jameson, F.: Paint Manu., 13, 6 (1943)<br></p>Fórmula:C2H3O2·6AsO2·4CuCor e Forma:NeatPeso molecular:1013.793,5-Dimethyl-4-nitropyridine 1-Oxide
CAS:<p>Applications 3,5-Dimethyl-4-nitropyridine 1-Oxide is an intermediate used to prepare 2-[(2-pyridylmethyl)thio or -sulfinyl]benzimidazoles as antiulcer agents.<br>References Nohara, A., et al.: U.S., US 4689333 A 19870825. (1987)<br></p>Fórmula:C7H8N2O3Cor e Forma:Off White SolidPeso molecular:168.50N-Desmethyl Rosuvastatin Disodium Salt Monohydrate
CAS:Produto Controlado<p>Applications Inhibits the enzyme HMG-CoA reductase in vitro.<br>References Endo, A., et al.: J. Antibiot., 32, 852 (1979), Alberts, A.W., et al.: Drug Invest., 2 (Suppl. 2), 9 (1990), Kuroda, M., et al.: Biochim. Biophys. Acta, 486, 70 (1977),<br></p>Fórmula:C21H24FN3Na2O6S•H2OCor e Forma:NeatPeso molecular:511.481802Pyochelin I and Pyochelin II
CAS:Produto Controlado<p>Impurity 2.5<br>Applications Pyochelin I and Pyochelin II are the two major siderophores produced and secreted by Pseudomonas aeruginosa PAO1 to assimilate iron. It also has trphenyltin (T809350) decomposition capacity.<br>References Braud, A., et al.: J. Bacteriol., 191, 3517 (2009); Sun, G., et al.: Appl. Environ. Microb., 72, 7264 (2006)<br></p>Fórmula:C14H16N2O3S2Cor e Forma:NeatPeso molecular:324.42α-Tocopherol Phosphate Disodium Salt
CAS:Produto ControladoFórmula:C29H49Na2O5PCor e Forma:White To Off-WhitePeso molecular:554.65Cholesteryl Acetate Dibromide(Mixture of Diastereomers)
CAS:Produto Controlado<p>Applications Cholesteryl Acetate Dibromide is an brominated intermediate in the synthesis of Cholesterol (C432501) derivatives.<br>References Kandutsch, A.A., et al.: J. Biol. Chem., 249, 6057 (1974);<br></p>Fórmula:C29H48Br2O2Cor e Forma:NeatPeso molecular:588.5Anastrozole Monoamide
CAS:<p>Impurity Anastrozole Monoamide Impurity<br>Applications Anastrozole Monoamide is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Fórmula:C17H21N5OCor e Forma:WhitePeso molecular:311.38N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide
CAS:Produto Controlado<p>Applications A Rosuvastatin (R700500) intermediate as HMG-CoA reductase inhibitor.<br>References Beck, et al.: J. Med. Chem., 33, 52 (1999),<br></p>Fórmula:C16H20FN3O3SCor e Forma:NeatPeso molecular:353.41N-Dechloroethyl Cyclophosphamide
CAS:<p>Stability Reacts with DMSO<br>Applications A metabolite of Cyclophosphamide (C988580).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bohnenstengel, F., et al.: Eur. J. Clin. Pharmacol., 51, 297 (1996), Busse, D., et al.: J. Clin. Oncol., 15, 188 (1997), Roy, P., et al.: Drug Metab. Dispos., 27, 655 (1999),<br></p>Fórmula:C5H12ClN2O2PCor e Forma:NeatPeso molecular:198.591,3-Propylene-d6 Thiourea
CAS:Produto Controlado<p>Applications 1,3-Propylene-d6 Thiourea (CAS# 1219802-05-7) is a useful isotopically labeled research compound.<br></p>Fórmula:C4H2D6N2SCor e Forma:NeatPeso molecular:122.2221-Acetyl-2-imidazolidinone
CAS:<p>Impurity Clonidine EP Impurity A<br>Applications 1-Acetyl-2-imidazolidinone (Clonidine EP Impurity A) is a synthetic reagent used in the preparation of triple [14C]-labelled moxonidine which is an antihypertensive compound.<br>References Czeskis, B., et al.: J. Labelled Comp. Radiopharm., 47, 699 (2004)<br></p>Fórmula:C5H8N2O2Cor e Forma:Off-WhitePeso molecular:128.13
![1,3-Dimethyl 2-[4-(methoxycarbonyl)-2-nitrophenyl]propanedioate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD476668.webp&w=3840&q=75)
![N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FF595380.webp&w=3840&q=75)
