Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(273.647 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.605 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.602 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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2-Naphthylamine
CAS:<p>Applications It is listed as a known human carcinogen. Used in manufacturing of dyes, as antioxidant in rubber.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References IARC Monographs, 4, 97 (1974),<br></p>Fórmula:C10H9NCor e Forma:RedPeso molecular:143.19[1-(2,4-Dihydroxyphenyl)-2-(3’,4’-dihydroxyphenyl)ethanone
CAS:Produto Controlado<p>Stability Store in Freezer<br>Applications [1-(2,4-Dihydroxyphenyl)-2-(3’,4’-dihydroxyphenyl)ethanone (cas# 887354-66-7) is a compound useful in organic synthesis.<br>References Biosci. Biotechnol. Biochem., 57(1), 107 (1993)<br></p>Fórmula:C14H12O5Cor e Forma:NeatPeso molecular:260.24N-Desmethyl (E)-α-Hydroxy Tamoxifen
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications N-Desmethyl (E)-α-Hydroxy Tamoxifen is a N-demethylated, α-Hydroxyated metabolite of Tamoxifen (T006000).<br>References Poon, G.K. et al.: Drug Metab.Dispos. 23,377 (1995); Teunissen, S.F. et al.: J. Pharmac. Biomed. Anal., 55, 518 (2011); Muerdter, T.E. et al.: Clin. Pharmacol. Therap., 89, 708 (2011);<br></p>Fórmula:C25H27NO2Cor e Forma:NeatPeso molecular:373.49p-Salicylic Acid 4-Sulfate Disodium Salt
CAS:Produto Controlado<p>Applications p-Salicylic Acid 4-Sulfate is a urine metabolite of Methylated paraben (B693600), an antimicrobial agent used in cosmetic products.<br>References Tsukamoto, H., et al: Chem. Pharma. Bull., 10, 86 (1962); Desai, N.B., et al.: J. Sci. Indust. Res., 14, 330 (1955);<br></p>Fórmula:C7H4O6S·2NaCor e Forma:NeatPeso molecular:262.154-Nitro-4’-aminodiphenyl Sulfone
CAS:<p>Applications An intermediate in the synthesis of the Daspone metabolite.<br></p>Fórmula:C12H10N2O4SCor e Forma:NeatPeso molecular:278.28trans Resveratrol 3-O-β-D-glucopyranoside, 98%
CAS:<p>Applications A Stilbenoid glucoside and is a major Resveratrol derivative.<br>References Jeong, E., et al.: Arch. Pharm. Res., 33, 1331 (2010), Larrosa, M., et al.: J. Med. Chem., 53, 7365 (2010), Nguyen, T., et al.: Food Chem., 124, 437 (2010),<br></p>Fórmula:C20H22O8Pureza:98%Cor e Forma:NeatPeso molecular:390.38(+)-Lycopsamine N-Oxide (>85%)
CAS:<p>Applications (+)-Lycopsamine N-Oxide, is occurs in pyrrolizidine alkaloid-containing plants, which are the most common poisonous plants affecting livestock, wildlife, and humans. Thye are being known as hepatotoxins and tumorigens.<br>References Qingsu, X., et al.: Chem. Res. Toxic., 26, 1384 (2013); Bosi,, C. F., et al.: Revista Brasileira de Farmacognosia, 23, 425 (2013);<br></p>Fórmula:C15H25NO6Pureza:>85%Cor e Forma:NeatPeso molecular:315.367,10-Dichloro-2-methoxybenzo[b][1,5]naphthyridine
CAS:Produto Controlado<p>Applications 7,10-Dichloro-2-methoxybenzo[b][1,5]naphthyridine is used in the preparation of pyronaridine.<br>References Li, J., et al.: PCT Int. Appl., 2013:1701510 (2013)<br></p>Fórmula:C13H8Cl2N2OCor e Forma:NeatPeso molecular:279.12Carboxymethyl Cellulose Ether Sodium Salt
CAS:Produto Controlado<p>Applications Carboxymethyl Cellulose Ether is used as a thickener to enhance rigidity and composition of pharmaceutical compounds as well as the stability of electrode slurries in composite electrodes. Also provides ion-exchange for chromotography media.<br>References Salerno, C. et al.: AAPS PharmSciTech., 11, 986 (2010); Porcher, W. et al. J. Electrochem. Soc., 156, A133 (2009); Wang, H. et al.: Biochem. Biophys. Res. Comm., 342, 349 (2006);<br></p>Fórmula:C2H4O3•xUnspecified•xNaCor e Forma:Neat2'-Amino-2'-deoxyadenosine
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 2'-Amino-2'-deoxyadenosine (cas# 10414-81-0) is a useful research chemical.<br></p>Fórmula:C10H14N6O3Cor e Forma:NeatPeso molecular:266.26N-Acetyl-4-aminosalicylic Acid
CAS:Produto Controlado<p>Impurity Metoclopramide EP Impurity H<br>Applications N-Acetyl-4-aminosalicylic Acid (Metoclopramide EP Impurity H) is hydroxybenzoic acid that is a versatile reactant used in the preparation of salicylanilide derivatives as inhibitors of the protein tyrosine kinase epidermal growth factor receptor.<br>References Liechti, C., et al.: Eur. J. Med. Chem., 39, 11 (2004);<br></p>Fórmula:C9H9NO4Cor e Forma:Off WhitePeso molecular:195.17Kinetin Riboside
CAS:Produto Controlado<p>Applications Used as an anticancer and antiviral agent.<br>References Cancer Res., 20, 1362 (1960), Virology, 38, 26 (1969),<br></p>Fórmula:C15H17N5O5Cor e Forma:NeatPeso molecular:347.33Edoxaban Tosylate Monohydrate
CAS:<p>Applications Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor.<br>References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)<br></p>Fórmula:C31H38ClN7O7S2•xH2OCor e Forma:White To Off-WhitePeso molecular:720.265-Chlorovaleric Acid
CAS:Produto Controlado<p>Applications 5-Chlorovaleric acid is used in the synthesis of β-cyclodextrins linked with a cyclohexyl group via an aza-Wittig reaction.<br>References Li, D. B., et al.: Tetrahedron, Lett., 43, 1871 (2002);<br></p>Fórmula:C5H9ClO2Cor e Forma:NeatPeso molecular:136.5771-(2-Nitroethyl)-2-naphthol
CAS:Produto Controlado<p>Applications 1-(2-Nitroethyl)-2-naphthol is an aromatic alcohol that is used in photoacid for extremely long lived and reversible pH jumps.<br>References Nunes, R.M.D., et al.: J. Am. Chem. Soc., 131, 26 (2009);<br></p>Fórmula:C12H11NO3Cor e Forma:NeatPeso molecular:217.222-(9H-Carbazol-1-yl)acetic Acid
CAS:Produto ControladoFórmula:C14H11NO2Cor e Forma:NeatPeso molecular:225.243Diclofenac Acyl-β-D-glucuronide Allyl Ester
CAS:Produto Controlado<p>Applications An intermediate for the synthesis of Diclofenac’s glucuronide metaoblite.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kenny, J.R., et al.: J. Med. Chem., 47, 2816 (2004),<br></p>Fórmula:C23H23Cl2NO8Cor e Forma:NeatPeso molecular:512.341-Acenaphthenol
CAS:<p>Applications 1-Acenaphthenol is a product of the microbial metabolism and photolysis of acenaphthene, of acenaphthene, a polycyclic hydrocarbon that has potential to act as polyploidizing agents in plants. 1-Acenaphthenol is also a known substrate of dihydrodiol dehydrogenases.<br>References Reyes, C., et al.: J. Photochem. Photobiol. A, 112, 277 (1998); Šavlík, M., et al.: Res. Vet. Sci., 83, 20 (2007); Schocken, M. & Gibson, D.: Appl. Environ. Microb., 48, 10 (1984);<br></p>Fórmula:C12H10OCor e Forma:NeatPeso molecular:170.211-Acetyl-2-imidazolidinone
CAS:<p>Impurity Clonidine EP Impurity A<br>Applications 1-Acetyl-2-imidazolidinone (Clonidine EP Impurity A) is a synthetic reagent used in the preparation of triple [14C]-labelled moxonidine which is an antihypertensive compound.<br>References Czeskis, B., et al.: J. Labelled Comp. Radiopharm., 47, 699 (2004)<br></p>Fórmula:C5H8N2O2Cor e Forma:Off-WhitePeso molecular:128.136-Hydroxy-2-naphthalenesulfonic Acid Sodium Salt
CAS:Produto Controlado<p>Applications 6-Hydroxy-2-naphthalenesulfonic Acid Sodium Salt is a coupling component used to prepare heterocyclic monoazo dyes.<br>References Naik, D., et al., Dyes and Pigments., 14,1 (1990); Bilimoria, J., et al.: Colourage, 57, 72 (2010)<br></p>Fórmula:C10H7O4S·NaCor e Forma:White To Off-WhitePeso molecular:246.22Thioaildenafil
CAS:<p>Applications A new Sildenafil (S435000) analogue.<br>References Balayssac, S., et al.: J. Pharm. Biomed. Anal., 50, 602 (2009),<br></p>Fórmula:C23H32N6O3S2Cor e Forma:NeatPeso molecular:504.67Drotaveraldine
CAS:Produto Controlado<p>Applications A metabolite of Drotaverine (D689700).<br>References Lalla, J.K., et al.: J. Pharma. Biomed. Anal., 11, 385 (1993),<br></p>Fórmula:C24H29NO5Cor e Forma:BeigePeso molecular:411.493-Iodothyroacetic Acid
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 3-Iodothyronacetic Acid is a 3-Iodothyronamine metabolite that has functional effects in FRTL-5 thyroid cells.<br>References Agretti, P. et al.: J. Mol. Endocrinol., 47, 23 (2011);<br></p>Fórmula:C14H11IO4Cor e Forma:NeatPeso molecular:370.1395-Chloro Hydrochlorothiazide
CAS:Produto Controlado<p>Impurity Hydrochlorothiazide 5-Chloro Impurity<br>Applications Hydrochlorothiazide derivative. Diuretic agent.<br>References Mayer, S.E., et al.: J. Pharmacol. Exp. Therap., 134, 18 (1961),<br></p>Fórmula:C7H7Cl2N3O4S2Cor e Forma:Off White SolidPeso molecular:332.182-(4’-Chlorobenzoyl)benzoic Acid
CAS:Produto Controlado<p>Applications 2-(4’-Chlorobenzoyl)benzoic Acid (cas# 85-56-3) is a compound useful in organic synthesis.<br></p>Fórmula:C14H9ClO3Cor e Forma:NeatPeso molecular:260.672Aldosterone 3-(O-Carboxymethyl)oxime (>80%)
CAS:Produto ControladoFórmula:C23H31NO7Cor e Forma:NeatPeso molecular:433.49Tilmicosin Phosphate Salt (~80%)
CAS:<p>Applications Tilmicosin Phosphate Salt is the phosphate salt of the semi-synthetic antibiotic derivative. It can be used in biological study and pharmacological activity of bactericidal effects of various concentrations of enrofloxacin, florfenicol, tilmicosin phosphate, and tulathromycin on clinical isolates of Mannheimia haemolytica from cattle.<br>References Blondeau, J., et al.: Am J Vet Res, 76, 860 (2015)<br></p>Fórmula:C46H80N2O13·H3O4PPureza:~80%Cor e Forma:NeatPeso molecular:967.13Benazepril Acyl-β-D-glucuronide
Produto Controlado<p>Stability Hygroscopic<br>Applications Used as an antihypertensive.This compound is very unstable in solution and will hydrolyze readily to give benazapril.<br></p>Fórmula:C30H36N2O11Pureza:>85%Cor e Forma:NeatPeso molecular:600.615-Chloronaphthalene-2-sulfonyl Chloride
CAS:Produto Controlado<p>Applications 5-Chloronaphthalene-2-sulfonyl Chloride (cas# 89108-45-2) is a compound useful in organic synthesis.<br></p>Fórmula:C10H6Cl2O2SCor e Forma:NeatPeso molecular:261.12(2-Chloroethyl) Phosphonic Acid-d4
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled (2-Chloroethyl)phosphonic acid. (2-Chloroethyl)phosphonic acid (Ethephon) is the most widely used plant growth regulator. Ethephon is often used on wheat, coffee, tobacco, cotton, and rice in order to help the plant's fruit reach maturity more quickly. The toxicity of Ethephon is actually very low, and any Ethephon used on the plant is converted very quickly to ethylene.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brantley, B., et al.: J. Plant Physiol., 1428, 741 (1960), Ntui, V., et al.: J. Food Agricult. Environ., 5, 211 (2007), Vwioko, E., et al.: Biosci. Res. Communic., 21, 263 (2009),<br></p>Fórmula:C22H4H2ClO3PCor e Forma:NeatPeso molecular:148.52(3E,8Z,11Z)-Tetradeca-3,8,11-trienyl Acetate (Technical Grade)
CAS:Produto Controlado<p>Applications (3E,8Z,11Z)-Tetradeca-3,8,11-trienyl Acetate is a compound found in the pheromones. It is a major sex pheromone component of the tomato pest.<br>References Attygalle, A., et al.: Bioorg. Med. Chem., 4, 305 (1996); Hungerford, N., Kitching, W.: J. Chem. Soc., Perkin Trans. 1, 1839 (1998);<br></p>Fórmula:C16H26O2Pureza:>75%Cor e Forma:NeatPeso molecular:250.38b-Cembrenediol
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications β-Cembrenediol is an inhibitor of tumor promotion. Novel c-Met inhibitors which are used in anticancer treatments.<br>References Le-Huu, P. et al.: ChemCatChem., 8, 3755 (2016); Ebrahim, H. et al.: Bioorg. Med. Chem., 24, 5748 (2016);<br></p>Fórmula:C20H34O2Cor e Forma:Off-WhitePeso molecular:306.48Dihydro Ferulic Acid 4-O-Sulfate Sodium Salt
CAS:Produto Controlado<p>Stability Very Hygroscopic!<br>Applications A metabolite profiling of hydroxycinnamate derivative in plasma and urine after the ingestion of coffee by humans: identification of biomarkers of coffee consumption.<br>References Buchanan, C., et al.: J. Sci. Food Agric., 71, 459 (1996), Andreasen, M., et al.: J. Agric. Food Chem., 49, 5679 (2001), Poquet, L., et al.: Drug Metab. Dispos., 36, 190 (2008),<br></p>Fórmula:C10H10Na2O7SCor e Forma:NeatPeso molecular:320.23ASM-DNT
CAS:<p>Applications N,N'-Di-2-naphthyl-1,4-phenylenediamine (cas# 93-46-9) is a useful research chemical.<br></p>Fórmula:C26H20N2Cor e Forma:NeatPeso molecular:360.45044-Hydroxy Atorvastatin Disodium Salt
CAS:<p>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),<br></p>Fórmula:C33H33FN2Na2O6Cor e Forma:White To BrownPeso molecular:618.60Betamethasone 9,11-Epoxide 17,21-Dipropionate
CAS:Produto Controlado<p>Impurity Betamethasone Dipropionate EP Impurity J<br>Applications Betamethasone 9,11-Epoxide 17,21-Dipropionate (Betamethasone Dipropionate EP Impurity F) is an impurity of Betamethasone (B327000), an antiinflammatory agent.<br>References Shou, M., et al.: J. Pharm. Biomed. Anal., 50, 356 (2009),<br></p>Fórmula:C28H36O7Cor e Forma:White To Off-WhitePeso molecular:484.58ent-Rosuvastatin Sodium Salt
CAS:Produto Controlado<p>Impurity Rosuvastatin EP Impurity G<br>Stability Hygroscopic<br>Applications ent-Rosuvastatin is an enantiomer of Rosuvastatin (R700500), an impurity which acts as a selective, competitive HMG-CoA reductase inhibitor (1). Antilipemic (2,3).<br>References 1. Watanabe, M. et al.: Bioorg. Med. Chem. 1997 Feb;5(2):437-44.2. Lee, E. et al.: Clin. Pharmacol. Ther. 2005 Oct;78(4):330-41.3. Ferdinand, C. et al.: Am. J. Cardiol. 2006 Jan 15;97(2):229-35.<br></p>Fórmula:C22H27FN3NaO6SCor e Forma:NeatPeso molecular:503.52Eplerenone Hydroxyacid Potassium Salt
CAS:Produto Controlado<p>Applications A metabolite of Eplerenone. Used in combination therapy for treatment of cardiovascular disorders.<br>References Staessen, J., et al.: J. Endocrinol., 91, 457 (1981), de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), MacFadyen, R., et al.: Cardiovasc. Res., 35, 30 (1997),<br></p>Fórmula:C24H31O7·KCor e Forma:Off-White To Light YellowPeso molecular:470.60Glutaric Acid-1,5-13C2
CAS:<p>Applications Glutaric Acid-1,5-13C2 (cas# 1185108-16-0) is a compound useful in organic synthesis.<br></p>Fórmula:C313C2H8O4Cor e Forma:NeatPeso molecular:134.1Carbimazole
CAS:<p>Applications Carbimazole, a prodrug of Methimazole (M260300), is used in the treatment of hyperthyroidism.<br>References Marchant, B., et al.: J. Clin. Endocrinol. Metab., 45, 1187 (1977), Johnsson, E., et al.: Lancet, 350, 1520 (1997),<br></p>Fórmula:C7H10N2O2SCor e Forma:NeatPeso molecular:186.23α-Propyl-α-(1-demethylethyl)-Verapamil Hydrochloride
CAS:Produto Controlado<p>Applications α-Propyl-α-(1-demethylethyl)-Verapamil is an impurity of Verapamil (V125000, HCl salt) which is a calcium channel blocker.<br>References Atlas, D, and Adler, M.: Proc. Natl. Acad. Sci. USA, 78, 1237 (1981), Janis, R., et al.: Adv. Drug. Res., 16, 309 (1987)<br></p>Fórmula:C27H38N2O4·ClHCor e Forma:NeatPeso molecular:491.06trans-Linalool Oxide
CAS:<p>Applications trans-Linalool Oxide is a derivative of Linalool (L465950), which is a terpene alcohol common in various flowers and spice plants. trans-Linalool Oxide is also an isomer of cis-Linalool Oxide, which has been employed to assess the effect of vine on the glycosylated flavour procurers in grapes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Baratta, M. T., et al.: J Essent Oil Res 10, 618 (1998); Bureau, S. M., et al.: J. Agric. Food Chem. 48, 1290 (2000)<br></p>Fórmula:C10H18O2Cor e Forma:NeatPeso molecular:170.25Betamethasone 17-Butyrate
CAS:Produto Controlado<p>Applications Betamethasone 17-Butyrate is an impurity of Clobetasone 17-Butyrate (C583550), an glucocorticoid used for anti-inflammatory purposes.<br></p>Fórmula:C26H35FO6Cor e Forma:NeatPeso molecular:462.551,2-Cyclohexanedicarboxylic Acid Mono 4-Methyl-7-carboxy-heptyl Ester-d8
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 1,2-Cyclohexanedicarboxylic Acid Mono 4-Methyl-7-carboxy-heptyl Ester-d8 is labelled 1,2-Cyclohexanedicarboxylic Acid Mono 4-Methyl-7-carboxy-heptyl Ester (C987315) which is a possible metabolite of the di(isononyl)cyclohexane-1,2-dicarboxylate (DINCH) monoester (MINCH).<br>References Koch, H., et al.: Arch. Toxicol., 87, 799 (2013)<br></p>Fórmula:C17H20D8O6Cor e Forma:NeatPeso molecular:336.45Androstenediol 3-Acetate
CAS:Produto Controlado<p>Applications Androstenediol 3-Acetate is an intermediate in the synthesis of Pregnenolone (P712200) which is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens.<br>References Stastna, E., et al.: Steroids., 75, 721 (2010);<br></p>Fórmula:C21H32O3Cor e Forma:NeatPeso molecular:332.48
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