Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(273.482 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.606 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.602 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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Nicergoline-d3
CAS:Produto Controlado<p>Applications Nicergoline-d3 is the labeled analogue of Nicergoline(N394550), a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia.<br>References Caraci, F., et. al.: Brain Res., 1047, 30 (2005); Mizuno, T., et. al.: Brain Res., 1066, 78 (2005)<br></p>Fórmula:C24D3H23BrN3O3Cor e Forma:NeatPeso molecular:487.4041,2-Dihydro Beclomethasone Dipropionate
CAS:Produto Controlado<p>Impurity Beclomethasone Dipropionate EP Impurity L<br>Applications 1,2-Dihydro Beclomethasone Dipropionate (Beclomethasone Dipropionate EP Impurity L) is an impurity of Beclomethasone Dipropionate (B131030).<br></p>Fórmula:C28H39ClO7Cor e Forma:NeatPeso molecular:523.06Triacetin-d5
CAS:Produto Controlado<p>Applications Triacetin-d5 is the isotope labelled analog of Triacetin (T720850); a compound used as a food additive and flavoring. Triacetin can be used as an excipient in pharmaceutical products where it is used as a humectant, a plasticizer, and as a solvent. Triacetin can also be used as a fuel additive as an antiknock agent.<br>References Mouret, A., et al.: Green Chem., 16 (1), 269 (2014); Snejdrova, E., et al.: Inter. J. Pharma., 458, 282 (2013)<br></p>Fórmula:C9D5H9O6Cor e Forma:NeatPeso molecular:218.2522-Hydroxycinnamic Acid
CAS:Produto Controlado<p>Applications 2-Hydroxycinnamic Acid (cas# 614-60-8) is a useful research chemical.<br></p>Fórmula:C9H8O3Cor e Forma:NeatPeso molecular:164.16α,2,4-Trichloroacetophenone
CAS:Produto Controlado<p>Applications α,2,4-Trichloroacetophenone is a reagent used in the synthesis of isoconazole, a potent antifungal agent.<br>References Dulcevscaia, G. et al.: Polyhed., 52, 106 (2013); Wang, Y. et al.: Bioorg. Med. Chem. Lett., 22, 5363 (2012);<br></p>Fórmula:C8H5Cl3OCor e Forma:NeatPeso molecular:223.48Magnesium Carbonate
CAS:Produto Controlado<p>Applications Magnesium Carbonate is a chemical reagent used in the production of magnesium oxide in the synthesis of ceramics.<br>References Seabra, M. et al.: Mat. Res. Bull., 37, 255 (2002); Kumar, T. et al.: Biomat., 21, 1623 (2000);<br></p>Fórmula:CO3·MgCor e Forma:White To Off-WhitePeso molecular:84.31α-Citral
CAS:<p>Applications α-Citral is an intermediate in the synthesis of 4,8-Dimethyl-1,3(E),7-nonatriene (D475810), which is a volatile compound released by corn plants in response to predation.<br>References Alborn, H,T,. et al.: Science, 276, 945 (1997)<br></p>Fórmula:C10H16OCor e Forma:Colourless To Light YellowPeso molecular:152.24Adapalene Methyl Ester
CAS:<p>Impurity Adapalene USP Related Compound B<br>Applications Adapalene intermediate, an ester of Adapalene. Adapalene USP Related Compound B.<br>References Charpentier, B., et al.: J. Med. Chem., 38, 4993 (1995),<br></p>Fórmula:C29H30O3Cor e Forma:NeatPeso molecular:426.55Fluorescein-Cadaverine Dihydrochloride
CAS:<p>Stability Hygroscopic<br>Applications Fluorescein-Cadaverine is a fluorescein derivative used in the preparation of biologically active fluorescent-labeled vitamin K analogues and monitoring of their subcellular distribution.<br>References Suhara, Y. et al.: Tetrahedron, 64, 8789 (2008);<br></p>Fórmula:C26H25N3O5S·2ClHCor e Forma:Orange SolidPeso molecular:564.481-Acenaphthenol
CAS:<p>Applications 1-Acenaphthenol is a product of the microbial metabolism and photolysis of acenaphthene, of acenaphthene, a polycyclic hydrocarbon that has potential to act as polyploidizing agents in plants. 1-Acenaphthenol is also a known substrate of dihydrodiol dehydrogenases.<br>References Reyes, C., et al.: J. Photochem. Photobiol. A, 112, 277 (1998); Šavlík, M., et al.: Res. Vet. Sci., 83, 20 (2007); Schocken, M. & Gibson, D.: Appl. Environ. Microb., 48, 10 (1984);<br></p>Fórmula:C12H10OCor e Forma:NeatPeso molecular:170.21Benzyl Cinnamate
CAS:<p>Applications BENZYL CINNAMATE (cas# 103-41-3) is a useful research chemical.<br></p>Fórmula:C16H14O2Cor e Forma:WhitePeso molecular:238.28(±)-α-Fenchol
CAS:<p>Applications (±)-α-Fenchol is found in essential oils from many plants. It has been studied for, insecticidal activity of essential oil from Helichrysum faradifani; antioxidant and antibacterial activity of essential oils from rhizome, leaf and stem of Etlingera sayapensis against growth of Bacillus subtilis, Escherichia coli and Candida albicans.<br>References Benelli G., et al., Nat. Prod. Res., 32, 690-1698 (2018); Mahdavi B., et al., Asian. Pac. J. Trop. Med., 10, 819-826 (2017)<br></p>Fórmula:C10H18OCor e Forma:NeatPeso molecular:154.25Hydroxy Urea-13C,15N2
CAS:Produto Controlado<p>Applications Labelled Hydroxyurea. An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.<br>References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),<br></p>Fórmula:CH4N2O2Cor e Forma:Off White SolidPeso molecular:79.03trans-2,cis-6-Nonadienal
CAS:<p>Applications trans-2,cis-6-Nonadienal is an unsaturated aldehyde that is responsible for the cucumber smell of Synura petersenii, a freshwater colonial flagellate. trans-2,cis-6-Nonadienal is also a common natural and drinking water contaminant.<br>References Berra, T., et al.: Trans. Am. Fish. Soc., 111, 78 (1982); Kynclova, A., et al.: Nova Hedw. Bei., 136, 283 (2010); Ömür-Özbek, P. & Dietrich, A.: Environ. Sci. Tech., 39, 3957 (2005)<br></p>Fórmula:C9H14OCor e Forma:NeatPeso molecular:138.218-Amino-5-[(4-hydroxyphenyl)amino]-2-naphthalenesulfonic Acid
CAS:Produto Controlado<p>Applications A diamino substituted nathalenesulfonic acid derivative.<br></p>Fórmula:C16H14N2O4SCor e Forma:NeatPeso molecular:330.358Carboxymethyl Cellulose Ether Sodium Salt
CAS:Produto Controlado<p>Applications Carboxymethyl Cellulose Ether is used as a thickener to enhance rigidity and composition of pharmaceutical compounds as well as the stability of electrode slurries in composite electrodes. Also provides ion-exchange for chromotography media.<br>References Salerno, C. et al.: AAPS PharmSciTech., 11, 986 (2010); Porcher, W. et al. J. Electrochem. Soc., 156, A133 (2009); Wang, H. et al.: Biochem. Biophys. Res. Comm., 342, 349 (2006);<br></p>Fórmula:C2H4O3•xUnspecified•xNaCor e Forma:NeatXanthurenic Acid-d4
CAS:Produto Controlado<p>Applications Labelled Xanthurenic Acid (X743500). Excreted by pyridoxine-deficient animals after the ingestion of tryptophan.<br>References Aquilina, J., et al.: Biochemistry, 39, 16176 (2000), Roberts, J., et al.: Photochem. Photobiol., 74, 740 (2001),<br></p>Fórmula:C102H4H3NO4Cor e Forma:NeatPeso molecular:209.19N-Nitrososarcosine-d3
CAS:Produto Controlado<p>Applications N-Nitrososarcosine-d3 is a labelled carcinogen compound.<br>References Lu, S., et al.: Cancer Res., 46, 1485 (1986), Tricker, A., et al.: Eur. J. Cancer Prev., 6, 226 (1997),<br></p>Fórmula:C32H3H3N2O3Cor e Forma:Light YellowPeso molecular:121.112,3,5-Tri-O-benzyl-D-ribono-1,4-lactone
CAS:Produto Controlado<p>Applications 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone (cas# 55094-52-5) is a useful research chemical.<br></p>Fórmula:C26H26O5Cor e Forma:NeatPeso molecular:418.482(2R,3S)-4-(2-Quinoxalinyl)-1,2,3-butanetriol
CAS:Produto Controlado<p>Applications A food metabolite.<br></p>Fórmula:C12H14N2O3Cor e Forma:Off-White To BeigePeso molecular:234.25N-(1-Naphthylmethyl)methylamine Hydrochloride
CAS:Produto Controlado<p>Impurity Terbinafine BP Impurity A; Terbinafine USP Related Compound A<br>Applications N-Methyl-1-naphthalenemethanamine hydrochloride (Terbinafine BP Impurity A; Terbinafine USP Related Compound A) is an intermediate used in the synthesis of various pharmaceuticals such as Terbinafine hydrochloride (T107500) and Butenafine hydrochloride (B690195).<br>References Petranyi, G., et al.: Science, 224, 1239 (1984); Ryder, N.S., et al.: Antimicrob. Agents Chemother., 27, 252 (1985); Evans, E.G.V., et al.: Br. Med. J., 318, 1031 (1999); Kokjohn, K., et al.: Int. J. Dermatol., 42, 11 (2003); Sumikawa, M., et al.: J. Dermatol., 34, 456 (2007)<br></p>Fórmula:C12H13N·ClHCor e Forma:WhitePeso molecular:207.70δ-Valerolactam-d4
CAS:Produto Controlado<p>Applications δ-Valerolactam-d4 is a labeled analog of δ-Valerolactam (V091440), which is a useful synthetic intermediate. It is an intermediate used to synthesize Cenicriviroc (C256550), an experimental drug candidate for the treatment of HIV infection. It is also a starting material for a new route to hexahydrojulolidines, using intramolecular 1,4-cycloaddition.<br>References Potts, K., et al. J. Org. Chem., 58, 5040 (1993); Klibanov, O., et al.: Curr. Opinion Invest. Drugs, 11, 940 (2010);<br></p>Fórmula:C5H5D4NOCor e Forma:NeatPeso molecular:103.16b-Cembrenediol
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications β-Cembrenediol is an inhibitor of tumor promotion. Novel c-Met inhibitors which are used in anticancer treatments.<br>References Le-Huu, P. et al.: ChemCatChem., 8, 3755 (2016); Ebrahim, H. et al.: Bioorg. Med. Chem., 24, 5748 (2016);<br></p>Fórmula:C20H34O2Cor e Forma:Off-WhitePeso molecular:306.48O,O-Dimethyl Dithiophosphate-13C2 Ammonium salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled dimethyl phosphorodithiolate derivatives used as insecticides.<br></p>Fórmula:C2H10NO2PS2Cor e Forma:Off-WhitePeso molecular:177.202,5-Dinitrophenol (Wetted with water >15%)
CAS:Produto Controlado<p>Applications 2,5-Dinitrophenol (wetted with ca. 20% Water) (unit weight on dry weight basis) is a useful reagent for the preparation of yttrium nitrophenolate aminebis(benzotriazolylphenolate) complexes.<br> E0<br>References Su, Y. C., et al.: J. Polym. Sci. A Polym. Chem., 57, 2038 (2019)<br></p>Fórmula:C6H4N2O5Cor e Forma:NeatPeso molecular:184.11Ethylene Urea-d4
CAS:Produto Controlado<p>Applications Ethylene Urea-d4 (cas# 62740-68-5) is a compound useful in organic synthesis.<br></p>Fórmula:C32H4H2N2OCor e Forma:NeatPeso molecular:90.12Robinetin
CAS:Produto Controlado<p>Applications Robinetin (cas# 490-31-3) is a useful research chemical.<br></p>Fórmula:C15H10O7Cor e Forma:NeatPeso molecular:302.245’-Deoxyfluorouridine-13C,15N2
CAS:Produto Controlado<p>Applications 5’-Deoxyfluorouridine-13C,15N2 is a compound useful in organic synthesis.<br></p>Fórmula:C8CH11FN2O5Cor e Forma:NeatPeso molecular:249.17Methyl-(4-nitrophenylethyl)-(4-nitrophenoxyethyl)amine
CAS:Produto Controlado<p>Applications Methyl-(4-nitrophenylethyl)-(4-nitrophenoxyethyl)amine (cas# 115287-37-1) is a compound useful in organic synthesis.<br></p>Fórmula:C17H19N3O5Cor e Forma:NeatPeso molecular:345.35Homogentisic Acid
CAS:<p>Applications An intermediate in the metabolism of tyrosine and phenylalanine. Occurs in plants and in the urine of alkaptonurics.<br>References Knox, W.E., et al.: Biochem. J., 49, 686 (1951), LaDu, B.N., et al.: J. Biol. Chem., 217, 777 (1955)<br></p>Fórmula:C8H8O4Cor e Forma:NeatPeso molecular:168.15(S)-(-)-Verapamil-d3 Hydrochloride
CAS:Produto Controlado<p>Applications (S)-(-)-Verapamil-d3 hydrochloride is deuterium labelled S-Verapamil (V124991). Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Peroutka, S., et al.: J. Ann. Neurol, 23, 500 (1988); Eliason, J.F., et al.: Int. J. Cancer, 46, 113 (1990)<br></p>Fórmula:C27H36D3ClN2O4Cor e Forma:NeatPeso molecular:494.08Urolithin A
CAS:<p>Applications Urolithin A is a major metabolite of ellagitannin and exhibits anti-inflammatory and antioxidant properties.<br>References Ishimoto, H., et. al.: Bioorg. Med. Chem. Lett., 21, 5901 (2011);<br></p>Fórmula:C13H8O4Cor e Forma:NeatPeso molecular:228.202-(2,3-Dichlorphenyl)-2-(guanidinylimino)acetonitrile
CAS:Produto ControladoFórmula:C9H7Cl2N5Cor e Forma:Light YellowPeso molecular:256.09N-(n-Butanesulfonyl)-O-[4-(4-pyridinyl)-butyl]-(S)-tyrosine
CAS:<p>Applications Tirofiban intermediate.<br></p>Fórmula:C22H30N2O5SCor e Forma:NeatPeso molecular:434.553-Sulfoglycolithocholic Acid Disodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 3-Sulfoglycolithocholic Acid Disodium Salt is a derivative of Lithocholic acid (L469180). Lithocholic acid (LCA) is a putative tumor promoter,that is shown to be able to inhibit mammalian DNA polymerase β.<br>References Ogawa, A., et al.: Jap. J. Canc. Res., 89, 1154 (1998)<br></p>Fórmula:C26H41NO7S·2NaCor e Forma:NeatPeso molecular:557.65(3R,5R)-Rosuvastatin Sodium Salt
CAS:<p>Impurity Rosuvastatin EP Impurity B<br>Stability Hygroscopic<br>Applications A diastereomer of Rosuvastatin (R700500) used for treatment, prevention and combination therapy of lipid-related disorders. Rosuvastatin EP Impurity B<br></p>Fórmula:C22H27FN3NaO6SCor e Forma:White To Light YellowPeso molecular:503.52Tenofovir Monohydrate
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Tenofovir Monohydrate is an HIV-1 RT inhibitor and antiretroviral drug.<br>References Zhao, Z., et al.: Method for preparing medical salts and/or derivatives of tenofovir disoproxil, and their application for preventing and/or treating HBV and HIV/AIDS infections, CN 101574356 (2009);<br></p>Fórmula:C9H14N5O4P·H2OCor e Forma:NeatPeso molecular:305.2322-Hydroxy Mifepristone
CAS:Produto Controlado<p>Applications A metabolite of Mifepristone.<br>References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Fórmula:C29H35NO3Cor e Forma:NeatPeso molecular:445.59Cinnamic Acid
CAS:Produto Controlado<p>Applications Cinnamic Acid is rac-form of trans-Cinnamic Acid (P336185) which is used in the synthesis of amides and esters through coupling reactions involving carboxylic acids and amines and N-methylation of amides and O-methylation of carboxylic acids.<br>References Kunishima, M. et al.: Tetrahedron, 55, 13159 (1999); Xia, Q. et al.: Org. Lett., 15, 3326 (2013);<br></p>Fórmula:C9H8O2Cor e Forma:White To Off-WhitePeso molecular:148.159Sodium Perfluoro-1-nonanesulfonate (50 ug/mL in Methanol)
CAS:Produto ControladoFórmula:C9F19O3S·NaCor e Forma:Single SolutionPeso molecular:572.12(4-Chloro-2-methylphenoxy-2,3,5-d3)acetic Acid
CAS:Produto Controlado<p>Applications Labelled derivative of (4-Chloro-2-methylphenoxy)acetic Acid (C369470).(4-Chloro-2-methylphenoxy)acetic Acid is a herbicide.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br>References Elliott, B., et al.: Mutagenesis, 20, 3 (2005); Pfleeger, T., et al.; Environmental Toxicology and Chemistry 30, 455 (2010);<br></p>Fórmula:C92H3H6ClO3Cor e Forma:White To Off-WhitePeso molecular:203.642-Ketoglutaric Acid-13C1
CAS:Produto Controlado<p>Applications Labelled 2-Ketoglutaric Acid is used in enzymic preparation and conversion to radiolabeled isocitric acid<br>References Ehrlich, R.S. et al.: Biochemistry, 26, 3461 (1987);<br></p>Fórmula:CC4H6O5Cor e Forma:NeatPeso molecular:147.09Cocamidopropyl Betaine (~30% aqueous solution)
CAS:<p>Applications Cocamidopropyl Betaine is a medium strength surfactant.<br></p>Fórmula:C19H38N2O3Cor e Forma:ColourlessPeso molecular:342.52O,N-Aminomethanylylidene-β-D-arabinofuranose
CAS:Produto Controlado<p>Applications O,N-Aminomethanylylidene-β-D-arabinofuranose (cas# 27963-98-0) is a compound useful in organic synthesis.<br></p>Fórmula:C6H10N2O4Cor e Forma:NeatPeso molecular:174.153-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt
CAS:Produto Controlado<p>Applications 3-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt is deuterium labeled 3-Cysteinylacetaminophen Trifluoroacetic Acid Salt (C994750), which is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).Minimum isotopic incorporation d-3, no d-0 present. A representative lot has 64% isotopic incorporation at the 6-position, 89% at the 4-position.<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C11H9D5N2O4S•C2HF3O2Cor e Forma:NeatPeso molecular:389.36Deschloro-N-ethyl-ketamine Hydrochloride (1 mg/ml in Acetonitrile)
CAS:Produto ControladoFórmula:C14H19NO·HClCor e Forma:Single SolutionPeso molecular:253.80Protoporphyrin-9
CAS:<p>Stability Light Sensitive<br>Applications Protoporphyrin-9 is the precursor to heme sites and chlorophyll.<br></p>Fórmula:C34H34N4O4Cor e Forma:NeatPeso molecular:562.662,3-Dihydroxy-1,4-naphthoquinone
CAS:Produto Controlado<p>Applications 2,3-dihydroxynaphthoquinone (cas# 605-37-8) is a useful research chemical.<br></p>Fórmula:C10H6O4Cor e Forma:NeatPeso molecular:190.15
![8-Amino-5-[(4-hydroxyphenyl)amino]-2-naphthalenesulfonic Acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FA611570.webp&w=3840&q=75)
![N-(n-Butanesulfonyl)-O-[4-(4-pyridinyl)-butyl]-(S)-tyrosine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FB690160.webp&w=3840&q=75)
