Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(273.474 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.603 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.602 produtos)
- Toxicologia(13.653 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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D-Tyrosine-d2
CAS:Produto Controlado<p>Applications D-Tyrosine-d2 is deuterium labelled D-Tyrosine (T899970). D-Tyrosine, the stereoisomer to L-Tyrosine (T899975), is an amino acid used in various organic syntheses for antibiotics. It is used in the synthesis of (-)-anisomycin, as well as BATSI (boronic acid transition state inhibitors) which act on β-lactamases. It has also been studied as an inhibitor of microbial growth on surfaces, reducing microbial attachment to hydrophillic glass and hydrophobic polypropylene surfaces.<br>References Li, Ji. et al.: Chin. Chem. Lett., 23, 647 (2012); Xu, H. et al.: Water Res., 45, 5796 (2011); Ke, W. et al.: Antimicrob. Agents Chemother., 55, 174 (2011)<br></p>Fórmula:C9D2H9NO3Cor e Forma:NeatPeso molecular:183.2O,N-Aminomethanylylidene-β-D-arabinofuranose
CAS:Produto Controlado<p>Applications O,N-Aminomethanylylidene-β-D-arabinofuranose (cas# 27963-98-0) is a compound useful in organic synthesis.<br></p>Fórmula:C6H10N2O4Cor e Forma:NeatPeso molecular:174.15Ginsenoside C-K
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Ginsenoside C-K is reported to exhibit anti-wrinkle effects. Also, it potentiates tumor necrosis factor (TNF)-related apotosis-inducing ligand (TRAIL)-induced apotosis in HCT116 colon cancer.<br>References Han, S., et al.: J. Cell. Biochem., (2017); Chen, L., et al.: Cell Death Diff., 7, 2334 (2016)<br></p>Fórmula:C36H62O8Cor e Forma:NeatPeso molecular:622.87Psilocin-d4 (1 mg/mL in Acetonitrile)
CAS:Produto ControladoFórmula:C12D4H12N2OCor e Forma:ColourlessPeso molecular:208.292-Phenyl-4’-trifluoromethylacetophenone
CAS:Produto Controlado<p>Applications 2-Phenyl-4’-trifluoromethylacetophenone, is used in the preparation of arylketones via palladium-tedicyp-catalyzed Heck reaction.<br>References Battace, A., et al.: Eur. J. Org. Chem., 19, 3122 (2007)<br></p>Fórmula:C15H11F3OCor e Forma:NeatPeso molecular:264.242Geraniol
CAS:Produto Controlado<p>Applications Geraniol is used in the synthesis of insect repellant. It is also used in the synthesis of Angelicoin A and Herecinone J, which inhibit collagen-induced platelet aggregation.<br>References Barnard, D. et al.: J. Med. Entomol., 41, 726 (2004); Mori K. et al.: Phytomedicine, 17, 1082 (2010);<br></p>Fórmula:C10H18OCor e Forma:ColourlessPeso molecular:154.25Allantoic Acid
CAS:Produto Controlado<p>Applications A metabolic intermediate in nucleic acid metabolism.<br>References Yoon, K., et al.: Nat. Prod. Sci., 14, 254 (2008), Ramazzina, I., et al.: J. Biol. Chem., 283, 23295 (2008), Kim, K., et al.: J. Mol. Biol., 387, 1067 (2009),<br></p>Fórmula:C4H8N4O4Cor e Forma:White To Off-WhitePeso molecular:176.137,10-Dichloro-2-methoxybenzo[b][1,5]naphthyridine
CAS:Produto Controlado<p>Applications 7,10-Dichloro-2-methoxybenzo[b][1,5]naphthyridine is used in the preparation of pyronaridine.<br>References Li, J., et al.: PCT Int. Appl., 2013:1701510 (2013)<br></p>Fórmula:C13H8Cl2N2OCor e Forma:NeatPeso molecular:279.122-Isopropylnaphthalene
CAS:Produto Controlado<p>Applications 2-Isopropylnaphthalene has been seen to likely act as CYP2F2 substrates through molecular modelling of the mouse cytochrome P450 CYP2F2.<br>References Lewis, D.F.V., et. al.: Drug Metab. and Drug Interact., 19, 97 (2002)<br></p>Fórmula:C13H14Cor e Forma:NeatPeso molecular:170.25Benzoic Acid
CAS:Produto Controlado<p>Impurity Mefenamic Acid EP Impurity D<br>Applications Benzoic Acid is used in the synthesis of 1,3,4-oxadiazoles with pharmaceutical activity. Also used in the synthesis of selective human A3 adenosine receptor antagonists.<br>References Rouhani, M. et al.: Ultrason. Biochem., 21, 262 (2014); Squarcialupi, L. et al.: J. Medic. Chem., 56, 2256 (2013);<br></p>Fórmula:C7H6O2Cor e Forma:WhitePeso molecular:122.1211b,21-dihydroxypregna-1,4,16-triene-3,20-dione
CAS:<p>Applications 11β,21-dihydroxypregna-1,4,16-triene-3,20-dione is a derivative of Prednisolone (P703740) and an intermediate in the synthesis of isoxazolinopregnadienes which exhibit anti-inflammatory activity.<br>References Khalil, M.A., et al.: Med. Chem. Res., 6, 52 (1996); Kwon, T., et al.: J. Med. Chem., 38, 1048 (1995)<br></p>Fórmula:C21H26O4Cor e Forma:NeatPeso molecular:342.43Tilmicosin Phosphate Salt (~80%)
CAS:<p>Applications Tilmicosin Phosphate Salt is the phosphate salt of the semi-synthetic antibiotic derivative. It can be used in biological study and pharmacological activity of bactericidal effects of various concentrations of enrofloxacin, florfenicol, tilmicosin phosphate, and tulathromycin on clinical isolates of Mannheimia haemolytica from cattle.<br>References Blondeau, J., et al.: Am J Vet Res, 76, 860 (2015)<br></p>Fórmula:C46H80N2O13·H3O4PPureza:~80%Cor e Forma:NeatPeso molecular:967.133,5-Bis(1,1-dimethylethyl)-4-hydroxy-benzenepropanoic Acid C7-9-Branched Alkyl Esters
CAS:<p>Applications Octyl-3,5-di-tert-butyl-4-hydroxyhydrocinnamate (cas# 125643-61-0) is an intermediate in synthesizing 7,9-Di-tert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione (D493755), an antioxidant naturally found in aerial parts of Gmelina asiatica Linn (Verbenaceae). It is also found in essential oils of some Stachys species from Mediterranean area. It is an impurity of Irganox used in the food packaging.<br>References Merlin, N., et al.: Pharmacogn. Res., 1, 152 (2009); Conforti, F., et al.: Food Chem., 116, 898 (2009), Riquet, A. et al.: Food Chem., 199, 59 (2016);<br></p>Fórmula:C25H42O3Cor e Forma:ColourlessPeso molecular:390.61Sodium Perfluoro-1-nonanesulfonate (50 ug/mL in Methanol)
CAS:Produto ControladoFórmula:C9F19O3S·NaCor e Forma:Single SolutionPeso molecular:572.121,3-Diphenylurea
CAS:<p>Applications 1,3-Diphenylurea (cas# 102-07-8) is a useful research chemical.<br></p>Fórmula:C13H12N2OCor e Forma:NeatPeso molecular:212.253',4',5'-Trifluoro-[1,1'-biphenyl]-2-amine
CAS:Produto Controlado<p>Applications 3',4',5'-Trifluoro-[1,1'-biphenyl]-2-amine is a building block used in various chemical synthesis.<br></p>Fórmula:C12H8F3NCor e Forma:NeatPeso molecular:223.192-Aminoanthracene
CAS:Produto Controlado<p>Stability Air Sensitive<br>Applications 2-AMINOANTHRACENE (cas# 613-13-8) is a useful research chemical.<br></p>Fórmula:C14H11NCor e Forma:NeatPeso molecular:193.246-Hydroxy-2-naphthalenesulfonic Acid Sodium Salt
CAS:Produto Controlado<p>Applications 6-Hydroxy-2-naphthalenesulfonic Acid Sodium Salt is a coupling component used to prepare heterocyclic monoazo dyes.<br>References Naik, D., et al., Dyes and Pigments., 14,1 (1990); Bilimoria, J., et al.: Colourage, 57, 72 (2010)<br></p>Fórmula:C10H7O4S·NaCor e Forma:White To Off-WhitePeso molecular:246.22N-(2-Hydroxyethyl)adenosine
CAS:Produto Controlado<p>Applications N-(2-Hydroxyethyl)adenosine has been studied as an anticonvulsant through the activation of adenosine A1 receptor (AA1R).<br>References Zhu, B-C., et al.: Junwu Xuebao, 35, 619-627 (2016);<br></p>Fórmula:C12H17N5O5Cor e Forma:NeatPeso molecular:311.295-Chlorovaleric Acid
CAS:Produto Controlado<p>Applications 5-Chlorovaleric acid is used in the synthesis of β-cyclodextrins linked with a cyclohexyl group via an aza-Wittig reaction.<br>References Li, D. B., et al.: Tetrahedron, Lett., 43, 1871 (2002);<br></p>Fórmula:C5H9ClO2Cor e Forma:NeatPeso molecular:136.577n-Pentyl 4-Hydroxybenzoate-2,3,5,6-d4
CAS:Produto Controlado<p>Applications n-Pentyl 4-Hydroxybenzoate-2,3,5,6-d4 (CAS# 1219798-66-9) is a useful isotopically labeled research compound.<br></p>Fórmula:C12H12D4O3Cor e Forma:NeatPeso molecular:212.281-Butylurea
CAS:<p>Applications 1-Butylurea is a compound used for developing cosmetic compositions for straightening hair fibers. It is also used as a reagent for the synthesis of chiral mono-, di-, tri-, and tetraalkylglycolurils by cyclocondensation of ureas with dihydroxyimidazolidinones or glyoxal.<br>References Plos, G., et al.: Fr. Demande, FR 3004926 A1 20141031 (2014); Kravchenko, A. N.,et al.: Russ Chem. Bull., 54, 691 (2005).<br></p>Fórmula:C5H12N2OCor e Forma:NeatPeso molecular:116.164-Hydroxychlorpropham Sulfate Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-Hydroxychlorpropham Sulfate Sodium Salt, is a chemical herbicide used in the protection of crops. It also maintains the ability to induce mitochondrial dysfunction in rat hepatocytes.<br>References EPA.: Fed. Reg., 72, 37646 (2007); Nakagawa, Y. et al.: Toxicol., 200, 123 (2004);<br></p>Fórmula:C10H11ClNNaO6SCor e Forma:NeatPeso molecular:331.705Pinic Acid (Diastereomeric Mixture)
CAS:Produto Controlado<p>Applications Pinic Acid (Diastereomeric Mixture) can be used to prepare pinic acid diamides as herbicides.<br>References Zou,R., et al.: Guangxi Daxue Xuebao, Ziran Kexueban, 36, 463 (2011);<br></p>Fórmula:C9H14O4Cor e Forma:NeatPeso molecular:186.21Succinyl Carnitine Chloride Salt
CAS:Produto Controlado<p>Stability Very Very Hygroscopic<br>Applications A metabolic intermediate of L-Carnitine.<br>References Huffman, K. et al.: Diab. Care, 32, 1678 (2009);<br></p>Fórmula:C11H20NO6ClCor e Forma:NeatPeso molecular:297.732-Hydroxycinnamic Acid
CAS:Produto Controlado<p>Applications 2-Hydroxycinnamic Acid (cas# 614-60-8) is a useful research chemical.<br></p>Fórmula:C9H8O3Cor e Forma:NeatPeso molecular:164.16N-Methylcytisine
CAS:<p>Applications N-Methylcytisine (cas# 486-86-2) is a compound useful in organic synthesis.<br></p>Fórmula:C12H16N2OCor e Forma:Off-WhitePeso molecular:204.274-(Methoxy-d3)-α-methyl-benzeneethanamine Hydrochloride
CAS:Produto Controlado<p>Applications 4-(Methoxy-d3)-α-methyl-(αS)-benzeneethanamine Hydrochloride is the labelled form of 4-Methoxyamphetamine Hydrochloride (M261015), which is the HCl salt of 4-Methoxyamphetamine. 4-Methoxyamphetamine is a designer drug belonging to the amphetamine class and releases 5-hydroxytryptamine in brain tissue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Menon, M., et al.: J. Pharmacol. Exp. Ther., 197, 272 (1976);<br></p>Fórmula:C10H12D3NO·HClCor e Forma:Off-WhitePeso molecular:204.71Anthracene
CAS:<p>Applications Anthracene is obtained from coal tar. It is an important source of many dyes.This compound is a contaminant of emerging concern (CECs)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C14H10Cor e Forma:Light Yellow To Light BrownPeso molecular:178.23Dihydroabietic Acid (Technical Grade)
CAS:Produto Controlado<p>Applications Dihydroabietic Acid is a resin acid reduction product and may be useful in the treatment of inflammation.<br>References Kang, M. et al.: Biochem. Biophys. Res. Comm., 369, 338 (2009);<br></p>Fórmula:C20H32O2Cor e Forma:NeatPeso molecular:304.467Methyl Isofenphos (Technical Grade)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Methyl Isofenphos is an organophosphorus compound, that according to biological studies, can cause acute toxicity to animals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Li, S.: Huanjing Wuran Yu Fangzhi, 20, 13 (1998); Yin, Y., et al.: Huanjing Yu Jiankang Zazhi, 28, 583 (2011)<br></p>Fórmula:C14H22NO4PSCor e Forma:ColourlessPeso molecular:331.373-Oxo-2-propylpentanoic Acid Methyl Ester
CAS:Produto Controlado<p>Applications Valproic Acid (V094750) derivative.<br></p>Fórmula:C9H16O3Cor e Forma:NeatPeso molecular:172.22Caffeic Acid-13C3
CAS:<p>Applications Constituent of plants, probably occurs in plants only in conjugated forms.<br>References Neish, et al.: Can. J. Biochem Physiol., 37, 1431 (1959), Krasemann, et al.: Arch. Pharm., et al.: 293, 721 (1960), Wolfrom, et al.: J. Agric. Food Chem., 8, 58 (1960),<br></p>Fórmula:C613C3H8O4Cor e Forma:NeatPeso molecular:183.14Acetyl-1,2-13C2 Coenzyme A Sodium Salt (~2% Unlabelled)
CAS:Produto Controlado<p>Applications Acetyl-1,2-13C2 Coenzyme A Sodium Salt is a useful synthetic intermediate.<br></p>Fórmula:C2113C2H38N7O17P3S•x(Na)Cor e Forma:NeatPeso molecular:811.562299Guanyl Urea Sulfate
CAS:<p>Applications It is used for detecting and determining Ni and its separation from Co and other metals.<br>References Jacob, K.D., et al.: J. Agric. Res., 28, 37 (1924),<br></p>Fórmula:C2H6N4O·H2O4SCor e Forma:NeatPeso molecular:302.271,3-Dimethylnaphthalene
CAS:Produto ControladoFórmula:C12H12Cor e Forma:ColourlessPeso molecular:156.223-Hydroxy Loratadine
CAS:Produto Controlado<p>Applications An intermediate for the preparation of 3-Hydroxy Desloratadine.<br></p>Fórmula:C22H23ClN2O3Cor e Forma:NeatPeso molecular:398.88N-Methyl-2-(4-nitrophenyl)ethanamine Hydrochloride
CAS:Produto Controlado<p>Applications N-Methyl-2-(4-nitrophenyl)ethanamine Hydrochloride is used as a reactant in the preparation of small molecule CDC25 phosphatases inhibitors.<br>References Contour-Galcera, Marie-Odile, et al.: Bioorg. & Med. Chem. Let., 14(23), 5809-5812 (2004)<br></p>Fórmula:C9H12N2O2·HClCor e Forma:NeatPeso molecular:216.66(2-Nitrophenyl)hydrazine (Contains ~30-40% water as stabilizer)
CAS:<p>Applications (2-Nitrophenyl)hydrazine (cas# 3034-19-3) is a useful research chemical.<br></p>Fórmula:C6H7N3O2Cor e Forma:NeatPeso molecular:153.142-Amino-1-naphthalenesulfonic Acid
CAS:Produto Controlado<p>Applications 2-Amino-1-naphthalenesulfonic Acid has been used in the preparation of oligomeric acid azo dyes and yields a reddish orange color in the dye.<br>References Shah, T.B., et. al.: Int. J. Polyemric Mater., 58, 681 (2009); Smith, K., et. al.: J. Environ., Res. Development, 2, 20 (2007)<br></p>Fórmula:C10H9NO3SCor e Forma:NeatPeso molecular:223.252-Naphthol-d7
CAS:Produto Controlado<p>Applications 2-Naphthol-d7 has been used as a reactant for the preparation of stable isotope-labeled internal standards of PAH metabolites from urine of smokers and nonsmokers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jacob, P. III, et. al.: Anal. Chem., 79, 587 (2007)<br></p>Fórmula:C102H7HOCor e Forma:NeatPeso molecular:151.21Beta-Estradiol 17-(Beta-D-Glucuronide) Sodium Salt
CAS:<p>Stability Hygroscopic<br>Applications beta-Estradiol 17-(beta-D-glucuronide) sodium salt is a glucocorticosteroid analog.<br></p>Fórmula:C24H31NaO8Cor e Forma:NeatPeso molecular:470.494'-Bromo-2,2':6',2''-terpyridine
CAS:Produto Controlado<p>Applications 4'-Bromo-2,2':6',2''-terpyridine (cas# 149817-62-9) is a useful research chemical.<br></p>Fórmula:C15H10BrN3Cor e Forma:NeatPeso molecular:312.16(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinecarboxylic Acid Phenylmethyl Ester
CAS:Produto ControladoFórmula:C30H28N6O3Cor e Forma:NeatPeso molecular:520.5825-Chloronaphthalene-2-sulfonyl Chloride
CAS:Produto Controlado<p>Applications 5-Chloronaphthalene-2-sulfonyl Chloride (cas# 89108-45-2) is a compound useful in organic synthesis.<br></p>Fórmula:C10H6Cl2O2SCor e Forma:NeatPeso molecular:261.123,3'-Dithiobis(propionohydrazide)
CAS:Produto Controlado<p>Applications 3,3'-dithiobis(propionohydrazide) (cas# 50906-77-9) is a useful research chemical.<br></p>Fórmula:C6H14N4O2S2Cor e Forma:NeatPeso molecular:238.33δ-Valerolactam-d4
CAS:Produto Controlado<p>Applications δ-Valerolactam-d4 is a labeled analog of δ-Valerolactam (V091440), which is a useful synthetic intermediate. It is an intermediate used to synthesize Cenicriviroc (C256550), an experimental drug candidate for the treatment of HIV infection. It is also a starting material for a new route to hexahydrojulolidines, using intramolecular 1,4-cycloaddition.<br>References Potts, K., et al. J. Org. Chem., 58, 5040 (1993); Klibanov, O., et al.: Curr. Opinion Invest. Drugs, 11, 940 (2010);<br></p>Fórmula:C5H5D4NOCor e Forma:NeatPeso molecular:103.16(2R,3S)-4-(2-Quinoxalinyl)-1,2,3-butanetriol
CAS:Produto Controlado<p>Applications A food metabolite.<br></p>Fórmula:C12H14N2O3Cor e Forma:Off-White To BeigePeso molecular:234.25L-Asparagine-13C4, 15N2 Hydrate
CAS:Produto ControladoFórmula:C4H815N2O3H2OCor e Forma:NeatPeso molecular:138.0818021,3-Diethylurea
CAS:Produto Controlado<p>Applications 1,3-Diethylurea<br></p>Fórmula:C5H12N2OCor e Forma:NeatPeso molecular:116.16
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