Glicociência

<p>Benzyl 4-C-nitromethyl-b-D-arabinopyranoside is a synthetic glycosylation agent that is used in the synthesis of complex carbohydrates. It has been shown to react with methyl, fluorine, and saccharide groups. This product can be modified to include a wide range of saccharides, including monosaccharides, disaccharides, and polysaccharides. Benzyl 4-C-nitromethyl-b-D-arabinopyranoside is also available in custom synthesis and high purity.</p>

<p>Tri-b-GalNAc-PEG5-sulfo-NHS ester is similar to tri-b-GalNAc-PEG5-NHS ester with the difference of the presence of a sulfo group introducing a negative charge to this molecule, potentially influencing its stability and interaction with biological systems. This negatively charged group can improve water solubility further compared to uncharged PEG linkers and potentially influence the biodistribution of the conjugate. The NHS ester, which permits further conjugation, and the unique properties of the sulfo group, permit the development of unique targeted drug-GalNAc conjugates for new therapies.</p>

<p>4,7,8,9-Tetra-O-acetyl-N-acetyl-D-neuraminic acid methyl ester is a modified form of sialic acid. This compound is a glycosylation product that has been modified with methyl groups and fluorine atoms. The fluorination of the molecule increases its stability and prevents it from being hydrolyzed by enzymes such as β-galactosidase. 4,7,8,9-Tetra-O-acetyl-N-acetyl-D-neuraminic acid methyl ester is often used in the synthesis of polysaccharides and oligosaccharides for medical purposes. This compound can be custom synthesized for research purposes or to meet special requirements.</p>

<p>α-6⁴-6³-Di-galactosyl-mannopentaose is a specialized oligosaccharide, which is a type of complex carbohydrate. This compound is derived from natural plant sources and its structure comprises a mannopentaose core linked with two galactose units. The mode of action involves specific interactions with gut microbiota, where it selectively enriches beneficial bacterial populations, such as Bifidobacteria and Lactobacilli. These interactions occur by serving as a fermentation substrate, promoting the growth of microbes that confer beneficial effects on host health.</p>

<p>Methyl 2,4,6-tri-O-acetyl-b-D-glucopyranoside is a modified sugar that is synthesized by a click reaction. This compound has been shown to be an efficient glycosylide donor for the synthesis of complex carbohydrates. Methyl 2,4,6-tri-O-acetyl-b-D-glucopyranoside has been used in the synthesis of oligosaccharides and glycosylated proteins.</p>

<p>A 2-acetamido-3,6-di-O-benzoyl-2-deoxy-a-D-glucopyranoside is a custom synthesis of a complex carbohydrate that has been modified with methylation and glycosylation. It is an Oligosaccharide with Polysaccharide and Modification. The CAS number for this compound is 82827-77-8 and has a purity of 99%. This compound has been fluorinated and synthesized.</p>

<p>Propranolol-2-O-b-D-glucuronide is a metabolite of propranolol hydrochloride. It has been shown to have low bioavailability in humans and rats. Propranolol-2-O-b-D-glucuronide is eliminated via the kidney, with an elimination rate that is faster than the parent drug propranolol hydrochloride. The glucuronide conjugate of propranolol, which is found in urine samples, has been shown to be a potential biomarker for glomerular filtration rate and renal function.</p>

<p>4-Fluorophenyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is a custom synthesis of an Oligosaccharide, Monosaccharide and Fluorination. It is a water soluble white powder with high purity.</p>

<p>2-O-Benzoyl-4,6-O-benzylidene-a-D-glucopyranoside is a synthetic carbohydrate with a structure that is similar to that of glucose. It has been shown to have anti-inflammatory properties in animal models and can be used for the treatment of inflammatory bowel disease and Crohn's disease. This compound has also been shown to inhibit the growth of bacteria such as Streptococcus pyogenes, Staphylococcus aureus, and Escherichia coli. 2-O-Benzoyl-4,6-O-benzylidene--aD glucopyranoside is soluble in water and has high purity with an average of 98%.</p>

<p>10-Beta-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-anthrone heptaacetate is a synthetic saccharide that can be used as a fluorescent probe. It is synthesized by reacting methyl anthrone with 10-beta-D-glucopyranosyl chloride and sodium hydroxide under basic conditions. The fluorination of the compound leads to its fluorescent properties. This product has been custom synthesized for use in click chemistry reactions.</p>

<p>Thioglucosides are a type of sugar that is modified with a thiol group at the C-3 position. A thioglucose can be synthesized by methylation, click modification, and fluorination. Thioglucoses have been used in the past for the production of oligosaccharides and polysaccharides, as well as in complex carbohydrate research. They are also used in the production of high purity monosaccharide sugars. This product is available for custom synthesis to meet your needs.</p>

<p>D-ribulose-5-phosphate sodium is a nucleotide sugar that is one of the ribonucleotides, which are fundamental components of RNA. D-ribulose 5-phosphate sodium has been shown to be an intermediate in the metabolism of ribulose and catalyzes the oxidation of d-arabinose. This enzyme also catalyses the synthesis of fatty acids and participates in reactions involving glycerolipids and phospholipids. The reaction mechanism involves a double displacement with simultaneous attack by a water molecule on C2' and C3'. When deuterium is present, it affects the rate of these reactions in a way that depends on the orientation of the substrate to the enzyme.</p>

<p>1,4:3,6-Dianhydrogalactitol (1,4:3,6-DAG) is a glycosylated sugar that belongs to the group of complex carbohydrates. It has been shown to be an effective inhibitor of methylation and Click modification reactions. 1,4:3,6-DAG also inhibits the polymerization of saccharides and oligosaccharides. This product is custom synthesized for research purposes and can be provided in high purity.</p>

<p>Phenyl 4-azido-2,3,6-tri-O-benzyl-4-deoxy-b-D-thioglucopyranoside is a fluorinated monosaccharide that can be synthesized from commercially available starting materials. The compound has been shown to inhibit the glycosylation of proteins and is used in the synthesis of complex carbohydrates such as oligosaccharides and polysaccharides. Phenyl 4-azido-2,3,6-tri-O-benzyl -4 deoxy -b D thioglucopyranoside is a white crystalline solid that has a melting point of 155 ˚C and an assay of 99% purity.</p>

<p>NGA2 Glycan, 2-AB labelled is a complex carbohydrate that is custom synthesized for research purposes. It is a high purity, high quality product that has been fluorinated and glycosylated. NGA2 Glycan, 2-AB labelled is used in the synthesis of oligosaccharides and polysaccharides. This product can be used for glycosylation, methylation and click modification.</p>

<p>Methyl 3,4-O-isopropylidene-L-threonate is a chromatographic chiral compound that is synthesized by the reaction of malonate and aspartyl amide. This product can be used to determine the stereochemistry of other chiral compounds. It is an endocannabinoid that has been found to have anti-inflammatory activities in animals. Methyl 3,4-O-isopropylidene-L-threonate has also been shown to have antiobesity effects in mice fed a high fat diet and may be used as a synthetic carbohydrate replacement for diabetics.</p>

<p>2-A-Methyl-5-a-androstan-3-a-ol-17-one glucuronide is a high purity, custom synthesis, synthetic glycosylation product. It is a carbohydrate (saccharide) that is modified by fluorination, methylation and glycosylation. The CAS number for this carbohydrate is 535745-06-4. This product has the following properties: Oligosaccharide, sugar, complex carbohydrate.</p>

<p>Monofucosyl, monosialyllacto-N-neohexaose-APD-HSA is a complex carbohydrate that is synthesized through the enzymatic polymerization of glucose. This synthetic oligosaccharide is composed of a single monosaccharide, fucose, and two sialic acid residues. Monofucosyl, monosialyllacto-N-neohexaose-APD-HSA can be used in the synthesis of various glycoconjugates such as glycoproteins, glycolipids, or proteoglycans. The chemical modification of this sugar molecule can also be performed to produce a variety of products with different properties.</p>

<p>4-O-Acetyl-3,6-di-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-1,2-ethyledine (CAS No. 230953-17) is a carbohydrate that has been modified with acetyl groups at the 3 and 6 positions of the monosaccharide unit. This modification is a complex carbohydrate that is made up of oligosaccharides and polysaccharides. The modification causes changes in the chemical properties of the carbohydrate compared to natural saccharides. 4-O-(2,3,4,6) tetra O acetyl a D mannopyranosyl 1 2 ethyledine b D mannopyranose has been used in synthesis of custom sugars for medical applications. It has also shown anti inflammatory activities against Mycobacterium tuberculosis and Mycobacterium avium complex</p>

<p>D-Xylulose 5-phosphate sodium salt is a synthetic monosaccharide that can be used in the synthesis of oligosaccharides, polysaccharides, and complex carbohydrates. It is also used in glycosylation reactions. D-Xylulose 5-phosphate sodium salt has been fluorinated to provide better stability and solubility. The compound has a molecular weight of 206.06 g/mol and a CAS number of 105931-44-0. This product is available for custom synthesis upon request.</p>

<p>4-Deoxy-D-glucose is a sugar that is synthesized by the condensation of two molecules of erythrose. It has been shown to be an efficient donor substrate for nucleophilic attack, which can lead to the synthesis of glycosides and other natural products. 4-Deoxy-D-glucose is also a competitive inhibitor of uridine diphosphate (UDP) glucose, which is an enzyme involved in the biosynthesis of UDP sugars and glycoproteins. The concentration of 4-deoxy-D-glucose affects its catalytic mechanism, as it acts as a competitive inhibitor at high concentrations. Molecular modeling has revealed that this molecule adopts a chair conformation with significant solvent exposure.</p>

<p>Maltotetraose-APD-HSA is a complex carbohydrate with a high purity. Maltotetraose-APD-HSA is a synthetic oligosaccharide that has been modified by glycosylation, methylation, and fluorination. It is an alpha 1,4 linked maltotetraose that has been conjugated to HSA. Maltotetraose-APD-HSA has the CAS number 113789-04-8 and its molecular weight is 495.7 Da. Maltotetraose-APD-HSA can be found in the monosaccharides saccharide and carbohydrate categories.</p>

<p>1,2,4,6-Tetra-O-acetyl-3-O-carbamoyl-D-mannopyranose is a synthetic sugar that belongs to the class of glycosides. It can be used in the synthesis of oligosaccharides and polysaccharides. This product is custom synthesized on request and can be modified with fluorination, methylation or click modification. It is available in high purity and has a CAS number of 99748-11-5.</p>

<p>Lacto-N-fucopentaose II-APD-HSA is a complex carbohydrate that has been chemically modified to include a fucose sugar. Lacto-N-fucopentaose II-APD-HSA is synthesized by the click reaction and then modified with the addition of an acetyl group. The product is then methylated and purified by HPLC. Lacto-N-fucopentaose II-APD-HSA can be used in a wide range of applications, including as a component in glycosylation reactions or as an adjuvant for fluorescence labelling.</p>

<p>1,5-α-L-Arabinohexaose is a carbohydrate. It is a nonreducing sugar that can be found in plants. 1,5-α-L-Arabinohexaose has an optimum pH of 5 and an ethanol concentration of 0.02%. The enzyme form of 1,5-α-L-Arabinohexaose is α-(1→6)-glycosidase. This enzyme hydrolyzes the α-(1→6) glycosidic bond between two glucose residues in a polysaccharide chain to produce β-(1→4) bonds. It also hydrolyzes the β-(1→4) glycosidic bond between two galactose residues to produce β-(1→2) bonds and oxidizes the terminal carbon atom to produce aldehyde products.<br>A structural analysis of this carbohydrate was conducted using marine microorganisms and it was found that they contain galacturonic acid and sugar residues</p>

<p>Globotriose conjugated to HSA via an aminophenylethyl spacer (APE)</p>

<p>2-Amino-2-deoxy-D-xylose is a metal chelator that can be used in the treatment of infections caused by bacteria. It has been shown to have synergistic effects with metaperiodate, a compound that inhibits bacterial growth by blocking the synthesis of folic acid. 2-Amino-2-deoxy-D-xylose also chelates and removes heavy metals such as mercury and lead from the bloodstream and other tissues. In addition, this drug is an efficient method for producing amino function pyrimidine nucleosides, which are precursors to DNA and RNA synthesis. The metal chelate ring is formed through dehydration of a furanose molecule with a chloride ion. This leads to an advanced carbohydrate product that contains chlorine.</p>

<p>Octyl b-D-mannopyranoside is a sugar that belongs to the group of complex carbohydrates. It is used in chemical synthesis and is commonly used for click modification, fluorination, glycosylation, carbamoylation, methylation, and other modifications. Octyl b-D-mannopyranoside is a white or off-white powder that can be dissolved in water or alcohols. It has a molecular weight of 536.88 g/mol.</p>

<p>3'-a-Sialyl-N-acetyllactosamine sodium salt is a high purity, custom synthesis sugar. It has been modified with fluorination, glycosylation, and methylation to provide the desired properties. This product is also available in other forms such as monosaccharide and saccharide. 3'-a-Sialyl-N-acetyllactosamine sodium salt can be used in various applications including Click modification, fluoroamination, glycosylation, carbonylation and methylation. CAS No. 350697-53-9</p>

<p>Methyl 6-azido-6-deoxy-a-D-glucopyranoside is a synthetic, fluorinated, complex carbohydrate that can be used as a building block for the synthesis of saccharides and oligosaccharides. It has been shown to inhibit the glycosylation of proteins and is a useful reagent in click chemistry. Methyl 6-azido-6-deoxy-a-D-glucopyranoside is a nonionic monosaccharide that has been modified with an azido group at C2 and a deoxy group at C3. The compound has been shown to have antiviral activity against HIV and influenza A virus.<br>Methyl 6-azido-6-deoxy--a--D--glucopyranoside is not soluble in water and is best stored at -20°C.</p>

<p>3,4-O-Isopropylidene-b-D-arabinopyranose is a synthetic monosaccharide that is used in the synthesis of oligosaccharides and polysaccharides. It can be fluorinated, methylated, or glycosylated to produce a range of compounds with different properties. 3,4-O-Isopropylidene-b-D-arabinopyranose is not active against bacteria, but it does inhibit the growth of yeast cells. In addition to its use in biochemistry and as a nutritional supplement for animals and humans, 3,4-O-Isopropylidene-b-D-arabinopyranose can be used as an additive for plastics and other materials.</p>

<p>D-Myo-inositol 1,4,5-triphosphate ammonium salt is a carbohydrate that can be synthesized from D-myo-inositol and phosphoric acid. D-Myo-inositol 1,4,5-triphosphate ammonium salt is a complex carbohydrate that has been fluorinated and glycosylated. It has been used as a synthetic intermediate in the synthesis of oligosaccharides and monosaccharides.</p>

<p>4-Glucopyranosylmannose is a disaccharide compound, which is a synthetic carbohydrate derived from the enzymatic or chemical glycosylation processes. It consists of glucose and mannose units linked through a glycosidic bond. The compound is sourced through advanced synthetic methodologies involving specific glycosyltransferases or chemical catalysts that facilitate the precise attachment of these sugar moieties.</p>

<p>Blood group B trisacchharide-APE-HSA is a synthetic carbohydrate that inhibits the synthesis of complex carbohydrates. The methylation of saccharides and polysaccharides can be accomplished by the addition of an amine to the 3′ hydroxyl group. In this reaction, the sugar is attached to a protein carrier (e.g., human serum albumin) via an amide bond, which prevents its degradation by proteases in the body. The modification of saccharides and polysaccharides is also accomplished through click chemistry, which is based on copper catalysis. This process involves attaching two functional groups through a copper-mediated reaction, forming a new carbon-carbon bond. Modification of saccharides and oligosaccharides can be accomplished using either chemical or enzymatic methods. Sugar modification can be achieved using high purity enzymes that have been custom synthesized for specific purposes (e.g., glycosylation). Carbohydrate modification can</p>

<p>D-myo-inositol-1,3,4,5-tetraphosphate (IP4) is a molecule that is involved in the regulation of cell metabolism and signal transduction. It is synthesized from myo-inositol by the enzyme inositol monophosphatase and hydrolyzed by inositol hexaphosphate kinase to form D-myo-inositol. IP4 can bind to receptors which span the plasma membrane and interact with intracellular Ca2+ channels. This binding results in an increase of cytosolic Ca2+ levels, which may be due to IP4’s ability to activate phosphatidylinositol turnover. IP4 is also involved in the regulation of neuronal death and infectious diseases such as HIV.</p>

<p>9,10-Dimethoxy-pterocarpane-3-O-b-D-glucoside is a custom synthesis that is a polysaccharide with a complex carbohydrate structure. The chemical name for this compound is 9,10-dimethoxy-pterocarpane-3-O-[4′″-(1″″′′)-b′″'-D-glucopyranosyl]-3′′′,4′″’,6′"’] bibenzyl. This compound has been modified by methylation and glycosylation. It can be used in the treatment of cancer and diabetes due to its high purity and fluorination. 9,10-Dimethoxy pterocarpane 3β O glucoside is a sugar or saccharide that can be found in plants such as the roots of tobacco plants. The modification of this sugar by methylation and glycosylation makes it more</p>

<p>Please enquire for more information about Carboxymethyl cellulose sodium - Viscosity 4000-6000 mPa·s including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Deoxy-L-idonojirimycin hydrochloride is a chaperone that is structurally related to the natural substrate, L-idonojirimycin. It has been found to interact with recombinant human Hsp70 and Hsp90. 1-Deoxy-L-idonojirimycin hydrochloride enhances the kinetic and thermodynamic parameters of these chaperones in vitro. The structural analysis of this compound revealed that it binds to both Hsp70 and Hsp90, which may be due to its ability to mimic the natural substrate's binding site on these chaperones.</p>

<p>Glucose 6-phosphatase substrate</p>

<p>Decyl D-glucopyranoside is a sodium salt of decyl D-glucopyranoside that is used as a detergent additive in cleaning compositions. Decyl D-glucopyranoside has shown antimicrobial activity against both Gram-positive and Gram-negative bacteria, including methicillin resistant Staphylococcus aureus (MRSA) and Clostridium perfringens. Decyl D-glucopyranoside has also been shown to have chemical stability at high temperatures, making it useful in the manufacture of lacrimal gland preparations and cationic surfactants.</p>

<p>3-Acetamido-3,6-dideoxy-D-galactose is a monosaccharide with two functional groups. It has been shown to be bifunctional and can act as a glycosyl donor or acceptor. 3-Acetamido-3,6-dideoxy-D-galactose was isolated from the type strain of Streptomyces venezuelae. It is also found in fatty acids and some strains of bacteria, such as Bacillus megaterium. The biological properties of 3-acetamido--3,6-dideoxy--D--galactose have been studied using monoclonal antibodies, magnetic resonance spectroscopy (MRS), and 13C nuclear magnetic resonance spectroscopy (NMR).</p>

<p>1-Deoxy-1-nitro-L-glucitol is a potent apoptosis-inducing compound that has shown promising results in cancer research. It is an analog of vanillin and nintedanib, two well-known cancer cell inhibitors. 1-Deoxy-1-nitro-L-glucitol has been shown to inhibit the activity of several kinases, including those involved in tumor growth and progression. In addition, it has been found to be effective against various types of cancer cells, including Chinese hamster ovary cells and human bladder cancer cells. This compound also exhibits synergistic effects with other anti-cancer drugs such as glimepiride and apomorphine. The presence of 1-Deoxy-1-nitro-L-glucitol in urine may serve as a potential biomarker for the diagnosis and monitoring of certain cancers.</p>

<p>Isosorbide is a dihydro-nitro sugar that belongs to the group of alkanoic acids. It is metabolized in the body by hydrolysis to yield two molecules of glucose and one molecule of nitrite ion. Isosorbide has been shown to have beneficial effects on chronic oral toxicity, systolic pressure, and myocardial infarct in experimental models. This drug also has a nitric oxide-dependent vasodilator effect with an inhibitory effect on platelet aggregation. Isosorbide has been shown to be effective against liver cells and is used as a diagnostic agent for liver diseases. In vivo human studies have demonstrated that this drug is absorbed quickly by the body and excreted primarily through the urine. This drug also exhibits pharmacokinetic properties that are dependent on pH levels for absorption.</p>

<p>Complex glucan (a 1-6) from Leuconostoc spp.; extender in blood transfusions</p>

<p>Ribitol is a sugar alcohol that is found in all living organisms. It is also used as a source of carbon and energy in the form of D-ribitol-5-phosphate, which can be synthesized from ribose 5-phosphate by means of an enzymatic reaction. Ribitol 5 phosphate is used for the synthesis of monoclonal antibodies, which are useful for studying enzyme activities, immunoassays, and cell surface receptors. This compound has been shown to have regulatory effects on the expression of genes encoding fatty acid biosynthesis enzymes. Ribitol 5 phosphate has been detected using magnetic resonance spectroscopy techniques in glycan structures and galacturonic acid residues.</p>

<p>Salacinol is a naturally occurring sulfonium ion, which is a bioactive compound found primarily in the roots and stems of the plant Salacia reticulata. This plant is native to regions of South Asia, particularly India and Sri Lanka, and is traditionally used in Ayurvedic medicine. Salacinol's mode of action involves the inhibition of alpha-glucosidase, an enzyme responsible for breaking down carbohydrates into glucose. By inhibiting this enzyme, salacinol reduces the postprandial rise in blood glucose levels, thus demonstrating antidiabetic potential.</p>