Glicociência

Lectins are carbohydrate-binding proteins that can be classified into different types based on their specificities for glycan structures. One of the most common types is the N-acetyl-D-glucosamine (NAG) lectin, which binds to oligomers of NAG and related sugars. Lectins are used to activate cells and induce cell death. The dodecyl NAG lectin has been shown to bind to glucocerebrosides in a reductively irreversible manner and has been used as a model for such interactions. This lectin is also inexpensively produced from a synthetic benzylidene acetal, which can be made from commercially available materials. It has been shown that this lectin binds to polyacrylamide gels in an SDS-polyacrylamide gel electrophoresis, with a pH optimum at 7.0 and an amino acid composition that includes glutamic acid, glutamine, asparagine, ser

D-Sedoheptulose is a sugar that is a member of the pentoses. It has been shown to have a ph optimum of 4.5 and oxidizing potential of -0.18 V. It is also an important intermediate in carbohydrate metabolism and can be used as an energy source by cells. D-Sedoheptulose plays a role in transcriptional regulation and cellular physiology, as well as being involved in the production of acyl chains and disulfide bonds for proteins. D-Sedoheptulose has also been found to have synergic effects with other sugars such as glucose, sucrose, or fructose, which may be due to its ability to act as an inducer of reductive enzymes such as glucose-6-phosphate dehydrogenase (G6PD).

Decyl D-glucopyranoside is a sodium salt of decyl D-glucopyranoside that is used as a detergent additive in cleaning compositions. Decyl D-glucopyranoside has shown antimicrobial activity against both Gram-positive and Gram-negative bacteria, including methicillin resistant Staphylococcus aureus (MRSA) and Clostridium perfringens. Decyl D-glucopyranoside has also been shown to have chemical stability at high temperatures, making it useful in the manufacture of lacrimal gland preparations and cationic surfactants.

Danaparoid sodium (the active pharmaceutical ingredient in Orgaran; Merck Sharp and Dohme) is a biopolymeric non-heparin drug that is used as anticoagulant and antithrombotic agent, approved for the prophylaxis of postoperative deep-vein thrombosis.  It consists of a mixture of three glycosaminoglycans: heparan sulphate, dermatan sulphate, and chondroitin sulphate.  Danaparoid, has well established antithrombotic activity. The drug has a high antifactor Xa to antifactor IIa (thrombin) activity ratio, a low tendency to cause bleeding and minimal effects on the fibrinolytic system.

2,4-O-Benzylidene-L-xylose is a white crystalline powder with a melting point of about 125°C. It is an acetate salt that can be used in the synthesis of many natural products. It has been shown to inhibit HMG-CoA reductase and is used in the treatment of hypercholesterolemia. The reaction mechanism for this compound is not well understood, but it is believed to involve an acid catalyst and an organic solvent. The yield for this compound is low and it requires a long reaction time due to its high reactivity.

N-Acetylneuraminic acid 9-phosphate is a sugar phosphate

D-[6-13C]Galacturonic acid potassium salt is a synthetic, water-soluble complex carbohydrate with a molecular weight of 744.2. It is used as a fluorescence probe in magnetic resonance imaging (MRI) and also has applications in the synthesis of oligosaccharides and polysaccharides. D-[6-13C]Galacturonic acid potassium salt is soluble in water and has an average pH of 5.0. This compound is available for custom synthesis with high purity and can be found under CAS number 144561-27-4.

Isosaccharinic acid is a bacterial strain that produces isosaccharinic acid as its main fatty acid. The thermodynamic data for the reaction mechanism of the conversion of glucose to isosaccharinic acid has been determined. Isosaccharinic acid formation is catalyzed by an enzyme called glycosyl-glycerate dehydrogenase, which converts glycerate to 3-hydroxypropanoic acid and then to 3-oxopropanoate before it undergoes decarboxylation and reduction to form isosaccharinic acid. Radionuclides such as TcO4 are used in chemical ionization mass spectrometry for the detection of this compound in samples. Neutral pH, high activation energies, and low binding constants are all factors that affect the stability of this molecule.

Daunorubicin-d3 is a fluorinated, monosaccharide, synthetic, oligosaccharide and complex carbohydrate. Custom synthesis of Daunorubicin-d3 is available with glycosylation, methylation and other modifications. Daunorubicin-d3 has CAS No. 1614-68-8 and purity >99%.

ADP-L-glycero-b-D-manno-heptose is a synthetic, fluorinated oligosaccharide that is custom synthesized and modified. It has a high purity level and CAS No., as well as being a complex carbohydrate that can be modified with methylation or click modification to generate desired properties. ADP-L-glycero-b-D-manno-heptose is an Oligosaccharide with a glycosylation and methylation. This compound can be used in the synthesis of saccharides, polysaccharides, or other complex carbohydrates.