Glicociência

<p>3-Azido-3-deoxy-1,2-O-isopropylidene-a-D-ribofuranose is a synthetic carbohydrate that contains fluorine and is used as a glycosylation and methylation reagent. It has been shown to react with various saccharides, including glucose, maltose, lactose, sucrose, and cellobiose. In addition to its use in glycosylation reactions, 3-azido-3-deoxy-1,2-O-isopropylidene -a D ribofuranose can be used for click chemistry. This reagent is available in high purity and is synthesized from the natural sugar ribofuranose.</p>

<p>Cellulose is a linear polysaccharide of β 1-4 linked glucose residues. The polysaccharide chains are bundled as microfibrils in cell walls and provide the essential structural components within growing plants. Each microfibril exhibits a high degree of three-dimensional internal bonding resulting in a crystalline structure that is insoluble in water, resistant to reagents and very strong. The crystalline region of cellulose is isolated to produce microcrystalline cellulose. Microcrystalline cellulose is a term for refined wood pulp and is used as a texturizer, an anti-caking agent, a fat substitute, an emulsifier, an extender, and a bulking agent in food production.</p>

<p>11a-Hydroxy progesterone b-D-glucuronide is a fluorinated steroid that is synthesized with high purity. It has been modified with methylation and glycosylation. 11a-Hydroxy progesterone b-D-glucuronide is a complex carbohydrate, which consists of saccharides in the form of oligosaccharides. The sugar in 11a-hydroxy progesterone b-D-glucuronide is a monosaccharide, which can be modified with fluorination or click chemistry to create a new compound. This product has CAS No. 77710-64-6 and can be custom synthesized to meet your specifications.</p>

<p>2-AB labeled core pentasaccharide found in most N-linked oligosaccharides.  Purified from the oligosaccharide pool released from bovine serum by hydrazinolysis using a combination of HPLC and glycosidase digestion.</p>

<p>Tetragalacturonic acid (α-1,4 galacturonotetraose) is derived from pectin or pectic acid by enzymatic or partial acid hydrolysis (Combo, 2012). It is used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s), and gluconase(s) (Jayani, 2005). The addition of very short fragments of homogalacturonan, tri-galacturonate, and tetra-galacturonate oligosaccharides restores development in dark-grown, de-etiolated seedling mutants, suggesting that they are unable to generate de-methylesterified pectin fragments. A model of spatiotemporally separated photoreceptive and signal-responsive cell types has been proposed, that contains overlapping subsets of the regulatory network of light-dependent seedling development (Sinclair, 2017).</p>

<p>Gum Jhingan is a modified carbohydrate with a fluorinated saccharide. It is an oligosaccharide that has been synthesized from the sugar galactose. Gum Jhingan is a high-purity, custom-synthesized product that has been methylated and glycosylated. The modification process of this carbohydrate includes fluorination and click chemistry.</p>

<p>Please enquire for more information about D-Glucoheptono-1,4-lactone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Polysorbate 60 is a polyoxyethylene-polyoxypropylene block copolymer that is composed of two different saturated fatty acid chains. It has been used as a surfactant and stabilizer in the manufacture of pharmaceuticals, foods, cosmetics, and other products. Polysorbate 60 has been shown to inhibit the growth of epidermal cells by binding to epidermal growth factor (EGF) receptors on the cell surface. The effects of polysorbate 60 are also mediated through hydrogen bonding with the EGF receptor. The pharmacokinetic properties of polysorbate 60 have been studied in vitro using human serum. This polymer is used as an excipient in solid dispersions for oral administration and can be administered intravenously or subcutaneously. Polysorbate 60 is chemically stable at acidic pH levels and hydrochloric acid does not affect its structure. Polysorbate 60 also has protease activity against trypsin at high temperatures,</p>

<p>a-D-Glucoheptonic acid calcium salt hydrate is a modification of a glycosylation reaction that is typically used in the synthesis of oligosaccharides. The modification is called Click chemistry, and it occurs through a copper-catalyzed reaction between an azide and an alkyne. This type of modification can be used to produce complex carbohydrates by linking together different monosaccharides or polysaccharides. It is also used for the production of high-purity monosaccharides and polysaccharides with custom syntheses. The methylation, glycosylation, fluorination, and saccharide modifications are all variations on this process.</p>

<p>1-Oxododecyl β-D-glucopyranoside is a synthetic compound that is used as an intermediate in the synthesis of oligosaccharides, monosaccharides, saccharides, and other carbohydrates. It has a purity of &gt;98% and can be custom synthesized to meet your specifications. 1-Oxododecyl β-D-glucopyranoside is also available for purchase with fluorination, glycosylation, and methylation modifications. The CAS number for this product is 64395-92-2.</p>

<p>4-Methoxyphenyl b-D-galactopyranoside is a custom synthesis of a sugar with an active methyl group. It is synthesized by the Click modification of 4-hydroxyphenyl b-D-galactopyranoside and has been fluorinated. The glycosylation process has been carried out using glycone as a precursor to modify the monosaccharide and oligosaccharide. This product has a CAS number of 3150-20-7 and is considered a synthetic compound.</p>

<p>Poria cocos is an edible medicinal fungus known as “Fuling” in Chinese that has been used as a Chinese traditional medicine for more than two thousand years. Polysaccharide material is the most abundant organic substance in the fungus, accounting for about 85% of the total and is a mixture of polysaccharides with the major component being Pachyman, a β-glucan with a 1,3 backbone and 1,6 side chains. It is reported that Pachyman has a wide range of biological activities including antitumour, immunomodulatory, anti-inflammatory and antioxidative properties. Pachyman is a beta-glucan with a 1,3 backbone and 1,6 side chains of fungal origin (Poria cocos).<br>The image was kindly provided by Dr. Chris Lawson.</p>

<p>Gamma-cyclodextrin (γ-CD) is a cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>3'-b-Sialyl-N-acetyllactosamine is an oligosaccharide that is synthesized from L-arabinose and 3'-phosphoadenosine 5'-phosphosulfate. It has a high degree of purity and is custom synthesized to order. The CAS number for this product is 210418-18-1.</p>

<p>2,3,4,6-Tetra-O-benzyl-D-galactono-1,5-lactone is an aldehyde that has been synthesized from tert-butyl bromoacetate and ethynyl acetate in the presence of cesium carbonate. It is an exocyclic aldehyde that forms a cyclic ester with glycine. The synthetic pathway was stereoselective because the exocyclic double bond was only formed on one face of the molecule. This product can be used as an intermediate for the synthesis of glycine analogues and glycines.</p>

<p>This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>Monofucosyllacto-N-hexaose II is a tetraol that is used as a reagent in the synthesis of enantioenriched and synthetically tetrasaccharidic products. Monofucosyllacto-N-hexaose II can be obtained by the reaction of Grignard reagents with glucose or by stereoselective reduction of an alpha, beta unsaturated ketone. The presence of the glucose residue in Monofucosyllacto-N-hexaose II makes it an acceptor for esterification reactions. This compound has chiral centers due to its two stereogenic centers at C2 and C3, which are both beta positions on the glucose residue. Monofucosyllacto-N-hexaose II also has a free hydroxyl group at C5 that can be esterified to produce chiral esters.</p>

<p>Methyl 2-azido-3,4,6-tri-O-acetyl-2-deoxy-bD mannoside is a custom synthesis that can be modified to suit the needs of the customer. It is an oligosaccharide and polysaccharide that has been modified with methylation and glycosylation. This product has CAS No. 97604-59-6 and is available for purchase in high purity with a purity level of at least 95%. Methyl 2-azido-3,4,6-triO acetyl -2 deoxy b D mannoside has been fluorinated to create a synthetic sugar.</p>

<p>Atorvastatin acyl-b-D-glucuronide is a synthetic compound that has been modified with fluorine and methyl groups. It is a glycosylated molecule with a carbohydrate moiety. It has been shown to be active against Saccharide-producing bacteria, such as the genus Clostridium, which are responsible for the production of polysaccharides and glycans.</p>

<p>β-1,3-Glucan is a bioactive polysaccharide, which is located predominantly in the cell walls of yeast, fungi, and certain cereals. This compound is characterized by its unique branched structure, which is crucial for its biological function. The mode of action of β-1,3-Glucan involves the binding to specific receptors on immune cells, such as dectin-1, which triggers a cascade of immune responses. This interaction enhances the activity of macrophages, neutrophils, and natural killer cells, thus bolstering the body's innate immune defenses.The uses and applications of β-1,3-Glucan are broad, primarily focused on immunological research and potential therapeutic strategies. It is extensively utilized in studies examining its effects as an immunomodulator, leveraging its ability to potentiate immune system function and examining its role in adjunctive cancer therapies, where it may enhance the efficacy of certain treatments. Additionally, β-1,3-Glucan is investigated for its potential benefits in reducing infection rates and improving recovery times in clinical settings. Moreover, its applications in dietary supplements and functional foods continue to be a subject of scientific inquiry, aiming to harness its health-promoting properties within nutrition science.</p>