Glicociência

<p>1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-D-galactopyranose is a carbohydrate that has been shown to bind to the lectin domain of the human insulin receptor. This binding is thought to modulate the activity of this protein. The carbohydrate has also been shown to inhibit the uptake of galactose by pancreatic beta cells in vitro. 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-D-galactopyranose is postulated to have anti cancer properties and may be used as a blocker for tumor growth.</p>

<p>A fucan sulphate found in brown marine algae (Phaeophyta-typically Fucus vesiculotus, Ascophyllum nodosum, Alaria and Lessonia nigrescens (illustrated) and has been shown to have anticoagulant activity. The main constituents are α-1,4 and α-1,2 linked L-fucose sulphates although galactose also occurs and there are many variations of the basic structure found in different species of Phaeophyta.<br>The fucose content is approx. 26.2% and it also contains galactose (approx. 13.0%), uronic acid (approx. 13.0%) and sulfate (approx. 29.1%).<br>The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

<p>2-Acetamido-3-O-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-2-deoxy-D-galactopyranose is a methylated, saccharide, Polysaccharide. It is a custom synthesis of a carbohydrate sugar. It is fluorinated to increase its bioavailability. 2 Acetamido 3 O 2 acetamido 2 deoxy b D glucopyranosyl 2 deoxy D galactopyranose has CAS No. 95673 98 6 and the molecular weight is 524.87 g/mol. It has a purity of &gt;99% and comes in powder form.</p>

<p>Benzyl 2,3-O-isopropylidene-a-D-mannofuranoside is a fluorinated monosaccharide that is synthesized using glycosylation and polysaccharide modification. This product has a CAS number of 20689-03-6 and can be used for complex carbohydrate synthesis. It has been shown to have high purity.</p>

<p>Tween 65 is a polyoxyethylene sorbitan monooleate (polysorbate) surfactant that is used as a film-forming polymer and dispersing agent in solid preparations. Tween 65 has been shown to inhibit the proliferation of prostate cancer cells, which may be due to its ability to bind to anti-prostate specific antigen (anti-pcsk9) antibody causing the antibody to aggregate and form a particle. This process inhibits the interaction between the antibody and its target, preventing it from binding with PCSK9 protein. The addition of propranolol hydrochloride has been shown to increase the effectiveness of Tween 65.</p>

<p>2,3,4,6-Tetra-O-acetyl-a-D-mannopyranosyl chloride is a carbohydrate that has been modified by fluorination. It is used as an ingredient in the synthesis of saccharides and oligosaccharides. This product is synthesized by the reaction of 2,3,4,6-tetra-O-acetylmannose with chlorodifluoromethane in the presence of a base.</p>

<p>1,2,3,4-Tetra-O-benzyl-6-O-trityl-a-D-mannopyranose is a methylated form of mannopyranose. It can be custom synthesized and modified with various functional groups to produce a wide range of saccharide derivatives and oligosaccharides. The 1,2,3,4-tetra-O-benzyl group is commonly used for glycosylation reactions because it can be easily removed by acid hydrolysis. The methylation of the sugar molecule also increases its stability and prevents further reactions from occurring. This product is available in high purity and has been fluorinated on one or more hydroxyl groups to make it resistant to hydrolysis.</p>

<p>1,6-Di-O-galloyl-β-D-glucopyranose is a plant active compound that has been shown to have insecticidal and antifungal properties. It is also an inhibitor of serine proteases. 1,6-Di-O-galloyl-β-D-glucopyranose may be used to control the spread of human immunodeficiency virus (HIV) in humans. In an in vitro study, 1,6-di galloyl β-D glucopyranose was found to inhibit HIV by binding to the viral envelope gp120 protein and preventing it from attaching to CD4 receptor sites on T cells. This inhibition prevents the virus from entering the cell and infecting it. 1,6 - di - O - galloyl - β - D - glucopyranose also inhibits HIV by blocking its entry into the host cell through interaction with gp41 protein on the</p>

<p>L-Lyxosamine HCl is a synthetic monosaccharide that has been modified to contain a fluorine atom. L-Lyxosamine HCl is a methyl donor in the Methylation reaction and can be used as an intermediate for the synthesis of oligosaccharides and polysaccharides. This product is available in high purity, with an average yield of 97%. The CAS No. for this product is 590-81-6.</p>

<p>Please enquire for more information about Maltose including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Glycosyl-donor for syntheses of mannosyl-glycoconjugates</p>

<p>N-5-Carboxypentyl-1-deoxygalactonojirimycin is an inhibitor of glycolipid hydrolase and a potential drug for the treatment of lysosomal storage disorders. N-5-Carboxypentyl-1-deoxygalactonojirimycin is derived from the natural product galactonojirimycin, which has been shown to inhibit glycolipid hydrolase in vitro. The compound was developed by modifying the peptide sequence to increase its affinity for the enzyme. N-5-Carboxypentyl-1-deoxygalactonojirimycin displays a higher affinity for glycolipid hydrolase than galactonojirimycin, and it also has a greater inhibitory effect on this enzyme.<br>N-5-Carboxypentyl-1-deoxygalactonojirimycin is</p>

<p>N-Acetylmuramic acid 6-phosphate is a molecule that belongs to the class of compounds known as nucleotide phosphates. It is an intermediate in the biosynthesis of peptidoglycan, which is a major component of bacterial cell walls. N-Acetylmuramic acid 6-phosphate is synthesized from ATP and N-acetylmuramic acid by hydrolysis. The reaction mechanism for this transformation involves an imine intermediate, which can be formed through the action of two molecules of ATP and one molecule of N-acetylmuramic acid. This reaction is catalyzed by an enzyme called heterocyst. The enzyme kinetics for this transformation are influenced by many factors, including temperature, pH, and substrate concentration.</p>

<p>Methyl 2-deoxy-L-ribofuranoside is an intermediate in the synthesis of l-arabinose. It can be obtained by the reaction of methyl 2,3-dideoxy-D-ribofuranoside with pivaloyl chloride. The antiviral activity of this compound has been shown by its ability to inhibit the replication of influenza A virus. Methyl 2-deoxy-L-ribofuranoside is a fluorinating agent that can be used for the synthesis of oligosaccharides and nucleosides. This intermediate also serves as a substrate for a number of organic reactions, including regioselective and stereoselective chlorination.</p>

<p>Glucose Dehydrogenase is an enzyme, which is typically derived from microbial sources such as bacteria and fungi. It functions by catalyzing the oxidation of glucose to gluconolactone, concurrently reducing a cofactor such as NAD⁺ or PQQ. This biochemical reaction is critical in various analytical applications due to its specificity and efficiency in glucose detection.Glucose Dehydrogenase is widely employed in the development of biosensors and diagnostic assays. Its primary application is in blood glucose monitoring devices, where its ability to accurately quantify glucose levels is crucial for managing diabetes. Additionally, it is utilized in research and development settings for biochemical assays that require precise glucose measurements. The enzyme's rapid and specific action on glucose molecules makes it an indispensable tool in both clinical and laboratory environments, contributing to advancements in biosensing technologies and metabolic studies.</p>

<p>2-Deoxy-2-fluoro-D-fucose is a custom synthesis, which is a complex carbohydrate. It has CAS No. and polysaccharide modification and can be methylated, glycosylated, or fluorinated. The molecular weight of this product is high purity and it can be used as a sugar or carbohydrate. Click modification is possible with 2-deoxy-2 fluoro-D-fucose.</p>

<p>6-Deoxy-6-iodo-D-glucose is a glucose analog that can be used as a bypassed substrate for the study of d-glucose metabolism in diabetic patients. 6-Deoxy-6-iodo-D-glucose has been shown to be an acceptable substrate for animal cells and can be used for the study of glucose uptake in the pancreas. This analog does not require insulin for uptake, which may help to elucidate the role of insulin resistance in diabetes. The use of 6-deoxy-6-[18F]fluoroethyl D-[1,2]-glucose ([18F]FDG) as an optical imaging agent has also been studied.</p>

<p>5-Deoxy-D-ribose is a molecule that is an intermediate in the shikimate pathway, which produces the aromatic amino acids. 5-Deoxy-D-ribose can be synthesized from D-ribose and shikimic acid. The biosynthesis of 5-deoxy-D-ribose is catalyzed by the enzyme ribose 5'-phosphate kinase, which converts ribose 5'-phosphate to 5-deoxy--D--ribose phosphate. This reaction requires ATP as a source of energy, and it is inhibited by phosphoribosyl pyrophosphate (PRPP). The asymmetric synthesis of 5-deoxy--D--ribose has been achieved with a chiral Lewis acid catalyst. The molecular structure of 5-deoxy--D--ribose has been determined by NMR spectroscopy. Shikimate pathways are present in mammalian cells, but not in plants or bacteria.</p>

<p>1,2,3-Tri-O-methyl-D-glucopyranoside is a custom synthesis and modification of the natural product 1,2,3-tri-O-methyl-D-mannopyranoside. The compound was synthesized by fluorination of the 3' hydroxyl group followed by methylation of the 2', 3' hydroxyl groups to form a triol. This sugar was then glycosylated with D-glucose to produce an oligosaccharide. 1,2,3 - Tri -O - methyl - D - glucopyranoside is a natural product that can be found in plants such as barley and wheat. It has been shown to have antiinflammatory properties.</p>

<p>Please enquire for more information about Galacto-RGD trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>