Glicociência

Astragaloside II is a natural compound that has been shown to have anti-inflammatory effects in vitro and in vivo. Astragaloside II inhibits the production of inflammatory mediators by inhibiting phosphodiesterase and cyclooxygenase pathways. It also has a matrix effect on the cells, which may be due to its ability to activate protein kinase C. This compound also has an analytical method, which consists of HPLC with UV detection at 210 nm.

UDP-a-D-xylose disodium is a high purity custom synthesis of sugar. It is also a Click modification and has been fluorinated, glycosylated, and methylated. This product contains CAS No. 108320-89-4 and has the following properties: Methylation, Modification, Oligosaccharide, Monosaccharide, saccharide, Carbohydrate, complex carbohydrate.

3-O-Acetyl-1,2-O-isopropylidene-a-D-galactofuranose is a modification of the carbohydrate structure galactofuranose. It has been custom synthesized and is available in high purity with a monosaccharide content of >99%. 3-O-Acetyl-1,2-O-isopropylidene-a-D-galactofuranose can be methylated or glycosylated and is used as a building block for the synthesis of complex carbohydrates. 3-O-Acetyl-1,2,3,4,6,7,8,-octahydrobenzo[b]naphtho[2,1b][1]benzopyran (CAS No. 109680) is also known as 3-(acetamido)-1,2:3',4'-diisopropyl

Lacto-N-fucopentaose III-BSA is a carbohydrate that is modified with fluorine. It is a complex carbohydrate that has been custom synthesized and methylated. Lacto-N-fucopentaose III-BSA is a high purity, synthetic oligosaccharide that has been glycosylated and click modified. The CAS number for this product is 73638-80-9.

1,2,3,4-Tetra-O-acetyl-L-xylopyranose is a custom synthesis product. It is a sugar that is found in glycosaminoglycans and proteoglycans. This product can be customized through the modification of the sugar with fluorination, methylation, acetylation or other modifications. This product has a CAS number of 142130-89-0 and can be synthesized from sucrose using Click chemistry. The chemical name for this compound is 1,2,3,4-Tetra-O-[(trimethylsilyl)acetyl]-L-xylopyranose.

GM3-ganglioside NBD (ammonium salt) has a core disaccharide structure (Galβ1,4Glc) with sialic acid linked α2,3 to the galactose residue with nitrobenzoxadiazole (NBD) linked β to position 1 on the reducing terminal glucose residue, in place of the ceramide fatty acid (Ledeen, 2009). Ganglioside GM3 is strongly associated with human tumors, such as, lung, brain, and melanomas, where it is frequently found to be overexpressed. GM3 ganglioside is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019). GM3 ganglioside is implicated in various other diseases involving chronic inflammation, such as: insulin resistance, leptin resistance, T-cell function, and immune disorders (e.g. allergic asthma). It has also been shown to play an essential role in murine and human auditory systems, and is a common pathological feature of GM3S deficiency is deafness (Inokuchi, 2018).

Phenyl 6-O-t-butyldimethylsilyl-b-D-thiogalactopyranoside is a custom synthesis that can be used to modify the fluoroquinolone antibiotic Gatifloxacin. It has been shown to inhibit the growth of bacteria in vitro and in vivo. Phenyl 6-O-t-butyldimethylsilyl-b-D-thiogalactopyranoside is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.

6-O-Benzoyl-3-O-tert-butyldiphenylsilyl-D-galactal is an oligosaccharide with a complex carbohydrate structure. It is prepared by the modification of D-galactal with benzoyl chloride and subsequent reaction with tert-butyl diphosphite. This compound has been shown to have antihypertensive properties and to inhibit the growth of tumor cells in culture. 6-O-Benzoyl-3-O-tert butyldiphenylsilyl D galactal is a fluorinated, high purity, synthetic sugar that is effective for inhibiting tumor growth in culture.