Antifúngicos
Os antifúngicos são compostos especificamente projetados para interromper, prevenir e eliminar o crescimento de fungos. Nesta categoria, você encontrará uma ampla variedade de agentes antifúngicos essenciais para pesquisa e aplicações terapêuticas. Esses compostos são cruciais no tratamento de infecções fúngicas e na prevenção de sua recorrência, tornando-os ferramentas vitais tanto em ambientes médicos quanto agrícolas. Pesquisadores e profissionais de saúde podem explorar inúmeros antifúngicos para entender seus mecanismos, otimizar sua eficácia e desenvolver novos tratamentos para combater cepas fúngicas resistentes. A extensa seleção de antifúngicos apoia os avanços contínuos na pesquisa sobre fungos e no desenvolvimento de terapias antifúngicas eficazes.
Foram encontrados 887 produtos de "Antifúngicos"
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41-Oxo-rapamycin
CAS:<p>41-Oxo-rapamycin is a synthetic derivative of rapamycin, which is a macrocyclic lactone. It is derived from Streptomyces hygroscopicus, a gram-positive bacterium known for producing various bioactive compounds. The mode of action of 41-Oxo-rapamycin involves binding to the FK506-binding protein (FKBP12), forming a complex that subsequently inhibits the mammalian target of rapamycin (mTOR) pathway. This inhibition results in the suppression of T-cell proliferation and modulation of immune responses.</p>Fórmula:C51H77NO13Pureza:Min. 95%Peso molecular:912.2 g/molCaerulomycin A
CAS:<p>Caerulomycin A is a bioactive compound classified as a natural broad-spectrum antibiotic, which is derived from various Streptomyces species found in soil. Its mode of action involves inhibiting fungal and bacterial growth by interfering with essential cellular processes, effectively curbing the proliferation of pathogenic microorganisms. This potent molecule achieves its effects by binding to specific cellular targets, thereby disrupting cell wall synthesis and other critical metabolic pathways.</p>Fórmula:C12H11N3O2Pureza:Min. 95%Peso molecular:229.23 g/molMiconazole
CAS:<p>Anti-fungal; sterol 14α-demethylase inhibitor</p>Fórmula:C18H14Cl4N2OPureza:Min. 95 Area-%Cor e Forma:White Off-White PowderPeso molecular:416.13 g/molBeauvericin
CAS:<p>Beauvericin is a cyclic peptide that is isolated from the fungus Fusarium. It has been shown to have antimicrobial activity against bacteria, as well as a variety of other biological properties. Beauvericin has been shown to inhibit mitochondrial membrane potential and induce toxicity in some animal models. Beauvericin also inhibits protein synthesis and causes cell death by inhibiting DNA polymerase activity. This compound is active against cancer cells, including HL-60 cells, which are derived from human lymphocytes and are used as a model for leukemia. Beauvericin can be extracted from an ETOA extract of the fungus Fusarium oxysporum; this extract has shown anti-cancer effects in vitro assays.</p>Fórmula:C45H57N3O9Pureza:Min. 95%Peso molecular:783.95 g/molEpocholeone
CAS:Epocholeone is a growth regulator and can be used for the control of fungal or physiological diseases of crops.Fórmula:C35H56O7Cor e Forma:SolidPeso molecular:588.81BI-10
CAS:BI-10, paired with fluconazole, hinders fungal growth, increases ROS, decreases MMP, and changes membrane permeability.Fórmula:C23H17BrN2OCor e Forma:SolidPeso molecular:417.3Metyltetraprole
CAS:Metyltetraprole: potent fungicide, effective against Zymoseptoria, low EC50 (0.002 ppm), inhibits respiratory chain.Fórmula:C19H17ClN6O2Cor e Forma:SolidPeso molecular:396.83P163-0892
CAS:P163-0892: potent, specific antifungal for Cryptococcus; moderate blood-brain barrier penetration.Fórmula:C19H20N2O3SCor e Forma:SolidPeso molecular:356.44Antifungal agent 22
CAS:<p>Orally active antifungal D16 (IC50: 0.5 μg/mL) passes blood-brain barrier, stable, low toxicity, targets C. neoformansH99 cells.</p>Fórmula:C21H26Cl3NOSCor e Forma:SolidPeso molecular:446.86Tropesin
CAS:Tropesin is a non-steroidal anti-inflammatory agent (NSAIA) that has inhibitory effects on the growth of Xylaria green.Fórmula:C28H24ClNO6Cor e Forma:SolidPeso molecular:505.95Posaconazole hydrate
CAS:Posaconazole: broad-spectrum antifungal, second-gen triazole, strong C14α demethylase inhibitor (IC50: 0.25 nM).Fórmula:C37H44F2N8O5Pureza:98%Cor e Forma:SolidPeso molecular:718.79Silthiofam
CAS:Silthiofam effectively combats Ggt, a wheat take-all fungus, now widely used for control in China.Fórmula:C13H21NOSSiPureza:98%Cor e Forma:SolidPeso molecular:267.46Antifungal agent 70
CAS:<p>Antifungal Agent 70 (Compound 13), a dihydroeugenol-imidazole, exhibits efficacy against multi-resistant Candida auris with a minimum inhibitory concentration (</p>Fórmula:C23H25ClN2O4Cor e Forma:SolidPeso molecular:428.91Fungicide4
CAS:Fungicide4 exhibits the high activity against the P. infestans strain.Fórmula:C14H11N3OCor e Forma:SolidPeso molecular:237.26Debneyol
CAS:Debneyol exhibits more potent fungicidal activity than validamycin.Fórmula:C15H26O2Cor e Forma:SolidPeso molecular:238.37Globosuxanthone A
CAS:Globosuxanthone A: a dihydroxanthenone with anticancer and antifungal properties (MIC: F. graminearum 4, F. solani 8, B. cinerea 16 μg/mL).Fórmula:C15H12O7Cor e Forma:SolidPeso molecular:304.25Zarilamide
CAS:Zarilamide disrupts microtubules, inhibiting mitosis in Phytophthora capsici zoospore cysts.Fórmula:C11H11ClN2O2Cor e Forma:SolidPeso molecular:238.67Antifungal agent 59
CAS:Antifungal agent 59 exhibits potent activity, reflected by MIC values ranging from 0.01 to 1 μg/mL, and inhibits the formation of fungal biofilms, whileFórmula:C18H15BrF2N2SeCor e Forma:SolidPeso molecular:456.19Chlordantoin
CAS:Chlordantoin is an antifungal agent with the potential for vaginal candidiasis treatment.Fórmula:C11H17Cl3N2O2SPureza:98%Cor e Forma:SolidPeso molecular:347.69
