Antifúngicos
Os antifúngicos são compostos especificamente projetados para interromper, prevenir e eliminar o crescimento de fungos. Nesta categoria, você encontrará uma ampla variedade de agentes antifúngicos essenciais para pesquisa e aplicações terapêuticas. Esses compostos são cruciais no tratamento de infecções fúngicas e na prevenção de sua recorrência, tornando-os ferramentas vitais tanto em ambientes médicos quanto agrícolas. Pesquisadores e profissionais de saúde podem explorar inúmeros antifúngicos para entender seus mecanismos, otimizar sua eficácia e desenvolver novos tratamentos para combater cepas fúngicas resistentes. A extensa seleção de antifúngicos apoia os avanços contínuos na pesquisa sobre fungos e no desenvolvimento de terapias antifúngicas eficazes.
Foram encontrados 908 produtos de "Antifúngicos"
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Levofloxacin
CAS:Levofloxacin is a fluoroquinolone antibiotic with a mode of action that inhibits bacterial DNA gyrase and topoisomerase IV. It is used for treating bacterial infections like pneumonia and urinary tract infections.Fórmula:C18H20FN3O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:361.37 g/molPropiconazole
CAS:Propiconazole is a triazole fungicide with action on fungal cell membranes by inhibiting ergosterol biosynthesis and is used for controlling fungal diseases in crops and turf.
Fórmula:C15H17Cl2N3O2Pureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:342.22 g/molNeoaureothin
CAS:Neoaureothin is a natural antibiotic product, which is derived from marine actinomycetes with a complex polyketide structure. Its mode of action involves the inhibition of bacterial protein synthesis by binding selectively to the ribosomal subunits, thereby obstructing the translation process in susceptible microbial strains. The specificity of its action allows it to target a broad spectrum of Gram-positive bacteria while presenting a lower risk of resistance development compared to traditional antibiotics.Fórmula:C28H31NO6Pureza:Min. 95%Peso molecular:477.5 g/molMiconazole
CAS:Anti-fungal; sterol 14α-demethylase inhibitorFórmula:C18H14Cl4N2OPureza:Min. 95 Area-%Cor e Forma:White Off-White PowderPeso molecular:416.13 g/molFilipin III
CAS:Filipin III is a polyene macrolide antibiotic, which is extracted from Streptomyces filipinensis. Known for its unique mode of action, Filipin III interferes with cholesterol-rich membranes by binding to ergosterol and cholesterol. This interaction disrupts the membrane structure, altering membrane permeability and ultimately affecting cell viability.
Pureza:Min. 95%Naftifine N-Oxide
CAS:Naftifine N-Oxide is an antifungal agent, which is derived from synthetic chemical processes. Its structure is based on the modification of the known antifungal, naftifine, by introducing an N-oxide functional group, which may enhance certain pharmacokinetic properties. As a synthetic derivative, Naftifine N-Oxide is specifically designed to interfere with the biosynthesis of ergosterol, an essential component of fungal cell membranes. By inhibiting squalene epoxidase, an enzyme crucial to the ergosterol pathway, Naftifine N-Oxide effectively disrupts the development and maintenance of the fungal cell membrane, compromising cell integrity and leading to antifungal activity.Fórmula:C21H21NOPureza:Min. 95%Peso molecular:303.4 g/molZelkovamycin
CAS:Zelkovamycin is a novel antibacterial compound isolated from endophytic microorganisms, specifically Streptomyces sp. Endophytes are bacteria or fungi that reside within plant tissues, forming symbiotic relationships and often producing bioactive metabolites. The mode of action of Zelkovamycin involves the inhibition of bacterial cell wall synthesis, interfering with the biosynthesis pathways essential for maintaining the structural integrity and function of bacterial cell walls, particularly in Gram-positive strains.Fórmula:C36H45N9O9SPureza:Min. 95%Cor e Forma:PowderPeso molecular:779.86 g/mol41-Oxo-rapamycin
CAS:41-Oxo-rapamycin is a synthetic derivative of rapamycin, which is a macrocyclic lactone. It is derived from Streptomyces hygroscopicus, a gram-positive bacterium known for producing various bioactive compounds. The mode of action of 41-Oxo-rapamycin involves binding to the FK506-binding protein (FKBP12), forming a complex that subsequently inhibits the mammalian target of rapamycin (mTOR) pathway. This inhibition results in the suppression of T-cell proliferation and modulation of immune responses.Fórmula:C51H77NO13Pureza:Min. 95%Peso molecular:912.2 g/molSordarin sodium salt
CAS:Sordarin sodium salt is an antifungal agent, characterized as a semisynthetic derivative produced from the fermentation products of filamentous fungi, specifically belonging to the phylum Ascomycota. This compound exerts its effects by selectively inhibiting fungal protein synthesis. It achieves this by obstructing the function of elongation factor 2 (EF-2), an essential component of fungal ribosomal activity, thereby disrupting the translational elongation step of protein synthesis.
Fórmula:C27H39NaO8Pureza:Min. 95%Peso molecular:514.58 g/molAntifungal agent 74
CAS:Antifungal agent 74 (compound 3c), is a potent substance that exhibits excellent fungicidal activity against C.Fórmula:C4HCl3N4SCor e Forma:SolidPeso molecular:243.5Ametoctradin
CAS:Ametoctradin is a Qo-site inhibitor of mitochondrial respiratory complex III and is used in the study of oomycete diseases.Fórmula:C15H25N5Pureza:99.65%Cor e Forma:SolidPeso molecular:275.39Prochloraz
CAS:Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.Fórmula:C15H16Cl3N3O2Pureza:99.75% - 99.79%Cor e Forma:Colorless SolidPeso molecular:376.67Bivittoside A
CAS:Bivittoside A is a non-sulfated hexoside analog obtained from Bovine sea cucumber with antifungal activity and potential antitumor activity.Fórmula:C41H66O12Pureza:98%Cor e Forma:SolidPeso molecular:750.96NSC-670224
CAS:NSC-670224 blocks HDAC6 and NF-κB, is toxic to yeast at low µM concentrations, similar to tamoxifen's action.Fórmula:C21H34Cl3NOPureza:98%Cor e Forma:SolidPeso molecular:422.86Iodiconazole
CAS:Iodiconazole, an azole antifungal, is used potentially for the treatment of fungal infection.Fórmula:C19H19F2IN4OPureza:98%Cor e Forma:SolidPeso molecular:484.28Tolciclate
CAS:Tolciclate is an agent of antifungal medication.Fórmula:C20H21NOSPureza:98%Cor e Forma:SolidPeso molecular:323.45Sortin2
CAS:Sortin2 is a sorting inhibitor that acts upstream from the morphological marker of lateral root primordium formation, the mitotic activity.Fórmula:C16H12ClNO5S3Pureza:98%Cor e Forma:SolidPeso molecular:429.92Mollugogenol A
CAS:Mollugogenol A: a Gammacerane saponin from Mollugo pentaphylla with antifungal and spermatocidal properties; damages sperm membrane.Fórmula:C30H52O4Cor e Forma:SolidPeso molecular:476.73Iprovalicarb
CAS:Iprovalicarb is a fungicide aimed at oomycetes.Fórmula:C18H28N2O3Pureza:98%Cor e Forma:SolidPeso molecular:320.43Benthiavalicarb isopropyl
CAS:Benthiavalicarb isopropyl is a fungicide, specifically targeting downy mildew and blight.Fórmula:C18H24FN3O3SPureza:98%Cor e Forma:SolidPeso molecular:381.46Aliconazole
CAS:Aliconazole is an imidazole derivative with antifungal activity for the study of skin infections.Fórmula:C18H13Cl3N2Pureza:99.21% - 99.79%Cor e Forma:SolidPeso molecular:363.67TCSA
CAS:TCSA is an inhibitor of fungal morphogenesis, biofilm formation, and host cell invasion.Fórmula:C13H8Cl3NO2Cor e Forma:SolidPeso molecular:316.57Fosravuconazole
CAS:Fosravuconazole is a ravuconazole prodrug. It has antifungal activity.Fórmula:C23H20F2N5O5PSPureza:98%Cor e Forma:SolidPeso molecular:547.47Epocholeone
CAS:Epocholeone is a growth regulator and can be used for the control of fungal or physiological diseases of crops.Fórmula:C35H56O7Cor e Forma:SolidPeso molecular:588.81Brassilexin
CAS:Brassilexin is a cyclobrassinin hydrolase inhibitor, a unique enzyme from the fungal pathogen Alternaria brassicicola.Fórmula:C9H6N2SPureza:98%Cor e Forma:SolidPeso molecular:174.22Succinate dehydrogenase-IN-1
CAS:Succinate dehydrogenase-IN-1 (Compound 34) acts as an inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 value of 0.94 μM and a KD of 22.4 μM. This compound also demonstrates antifungal activity, with EC50 values against Rhizoctonia solani, Sclerotinia sclerotiorum, Monilinia fructicola, and Botrytis cinerea measured at 0.04 μM, 1.13 μM, 1.61 μM, and 1.21 μM, respectively.Fórmula:C20H13F6N3OCor e Forma:SolidPeso molecular:425.33Tebuconazole-d9
CAS:Tebuconazole-d9 is a GC/LC-MS standard for quantifying the triazole fungicide tebuconazole, affecting seed/foliar fungi and androgen receptors.Fórmula:C16H13ClD9N3OCor e Forma:SolidPeso molecular:316.87Antifungal agent 73
CAS:Antifungal agent 73 (compound A32) effectively combats azole-resistant candidiasis by disrupting the fungal cell wall and membrane.Fórmula:C21H16Cl2N2O3Cor e Forma:SolidPeso molecular:415.27SCY-078 phosphate
CAS:SCY-078 phosphate is a novel glucan synthesis inhibitor.Fórmula:C44H70N5O8PCor e Forma:SolidPeso molecular:828.04Buclosamide
CAS:Buclosamide is a topical antimycotic agent that can be used in dermatomycoses [1].Fórmula:C11H14ClNO2Cor e Forma:SolidPeso molecular:227.69Antifungal agent 69
CAS:Antifungal agent 69 (compound 13), a eugenol-imidazole derivative, demonstrates targeted activity against Candida albicans with a minimum inhibitoryFórmula:C23H23ClN2O4Cor e Forma:SolidPeso molecular:426.89Haloprogin
CAS:Haloprogin is an antifungal agent with inhibitory activity against dermatophytes, Candida, and some Gram-positive bacteria.Fórmula:C9H4Cl3IOPureza:98.18%Cor e Forma:SolidPeso molecular:361.39SCH51048
CAS:SCH 51048 is a broad spectrum antifungal with oral activity.Fórmula:C37H42F2N8O3Cor e Forma:SolidPeso molecular:684.78D13
CAS:D13 acylhydrazone antifungal; MIC80: 0.06 μg/ml vs. C. neoformans; boosts mouse survival against fungal infections at 20 mg/kg/day orally.Fórmula:C14H9Br3N2O2Cor e Forma:SolidPeso molecular:476.95Stemphyperylenol
CAS:Stemphyperylenol: antifungal, targets Alternaria solani, MIC at 1.57 μM.Fórmula:C20H16O6Cor e Forma:SolidPeso molecular:352.34Flutolanil
CAS:Flutolanil: a fungicide targeting R. solani in rice, toxic to zebrafish.Fórmula:C17H16F3NO2Cor e Forma:SolidPeso molecular:323.31(Z)-Fluoxastrobin
CAS:(Z)-Fluoxastrobin is a fungicide that exhibits effective control of important seed and soil-borne pathogens.Fórmula:C21H16ClFN4O5Cor e Forma:SolidPeso molecular:458.83Antifungal agent 31
CAS:Orally active triazole, antifungal 31 with pyrrolizinone structure, combats Candida, reduces mortality and renal infection in mice.Fórmula:C25H22F2N6O3Cor e Forma:SolidPeso molecular:492.48Exalamide
CAS:Exalamide (2-(Hexyloxy)benzamide) is an aromatic amide with antifungal activity used in the study of dermatophytes.Fórmula:C13H19NO2Pureza:99.61%Cor e Forma:White PowderPeso molecular:221.3Asulam-potassium
CAS:Asulam-potassium is a dihydropteroate synthase inhibitor used as an herbicide (mainly for killing bracken). It contains an asulam(1-).Fórmula:C8H9KN2O4SCor e Forma:SolidPeso molecular:268.33Etisazole
CAS:Etisazole is an animal antifungal agent with skin sensitizing properties to humans.Fórmula:C9H10N2SCor e Forma:SolidPeso molecular:178.25Chitin synthase inhibitor 3
CAS:Compound 2d is a potent chitin synthase inhibitor (IC50: 0.16 mM, MIC: 1 μg/mL vs. Candida albicans) with antifungal properties.Fórmula:C20H19N3O4Cor e Forma:SolidPeso molecular:365.38Chlordantoin
CAS:Chlordantoin is an antifungal agent with the potential for vaginal candidiasis treatment.Fórmula:C11H17Cl3N2O2SPureza:98%Cor e Forma:SolidPeso molecular:347.69Antifungal agent 59
CAS:Antifungal agent 59 exhibits potent activity, reflected by MIC values ranging from 0.01 to 1 μg/mL, and inhibits the formation of fungal biofilms, whileFórmula:C18H15BrF2N2SeCor e Forma:SolidPeso molecular:456.19Zarilamide
CAS:Zarilamide disrupts microtubules, inhibiting mitosis in Phytophthora capsici zoospore cysts.Fórmula:C11H11ClN2O2Cor e Forma:SolidPeso molecular:238.67Globosuxanthone A
CAS:Globosuxanthone A: a dihydroxanthenone with anticancer and antifungal properties (MIC: F. graminearum 4, F. solani 8, B. cinerea 16 μg/mL).Fórmula:C15H12O7Cor e Forma:SolidPeso molecular:304.25Silthiofam
CAS:Silthiofam effectively combats Ggt, a wheat take-all fungus, now widely used for control in China.Fórmula:C13H21NOSSiPureza:98%Cor e Forma:SolidPeso molecular:267.46Posaconazole hydrate
CAS:Posaconazole: broad-spectrum antifungal, second-gen triazole, strong C14α demethylase inhibitor (IC50: 0.25 nM).Fórmula:C37H44F2N8O5Pureza:98%Cor e Forma:SolidPeso molecular:718.79Antifungal agent 22
CAS:Orally active antifungal D16 (IC50: 0.5 μg/mL) passes blood-brain barrier, stable, low toxicity, targets C. neoformansH99 cells.Fórmula:C21H26Cl3NOSCor e Forma:SolidPeso molecular:446.86
