Antifúngicos
Os antifúngicos são compostos especificamente projetados para interromper, prevenir e eliminar o crescimento de fungos. Nesta categoria, você encontrará uma ampla variedade de agentes antifúngicos essenciais para pesquisa e aplicações terapêuticas. Esses compostos são cruciais no tratamento de infecções fúngicas e na prevenção de sua recorrência, tornando-os ferramentas vitais tanto em ambientes médicos quanto agrícolas. Pesquisadores e profissionais de saúde podem explorar inúmeros antifúngicos para entender seus mecanismos, otimizar sua eficácia e desenvolver novos tratamentos para combater cepas fúngicas resistentes. A extensa seleção de antifúngicos apoia os avanços contínuos na pesquisa sobre fungos e no desenvolvimento de terapias antifúngicas eficazes.
Foram encontrados 908 produtos de "Antifúngicos"
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Ofurace
CAS:Ofurace is a fungicide.Fórmula:C14H16ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:281.73Pyribencarb
CAS:Pyribencarb, a benzylcarbamate-type fungicide, exhibits broad-spectrum activity against various plant pathogenic fungi.Fórmula:C18H20ClN3O3Pureza:99.75%Cor e Forma:SolidPeso molecular:361.82Antifungal agent 2
CAS:Antifungal agent 2 suppresses growth of Cryptococcus, Candida, Aspergillus at ≥0.5 μg/mL.Fórmula:C19H11Br2F3N4O2Pureza:98%Cor e Forma:SolidPeso molecular:544.12Lipoxamycin
CAS:Lipoxamycin is an inhibitor of serine palmitoyl-transferase.Fórmula:C19H36N2O5Pureza:98%Cor e Forma:SolidPeso molecular:372.541F5
CAS:41F5: Anti-fungal with MIC50 0.4-0.8 μM and IC50 0.87 μM against Histoplasma; 62x more selective for yeast vs host cells.Fórmula:C21H22N2OSCor e Forma:SolidPeso molecular:350.4816,17-Dihydroheronamide C
CAS:16,17-Dihydroheronamide C is a probe used for the analysis of the mode of action of heronamide C, which has antifungal properties.Fórmula:C29H41NO3Cor e Forma:SolidPeso molecular:451.64Antifungal agent 36
CAS:Antifungal agent 36 is a potent anti-fungal agent that shows anti-fungal activity for Basidiomycetes [1].Fórmula:C14H21NO2Cor e Forma:SolidPeso molecular:235.32Antifungal agent 65
CAS:Compound 5d (Antifungal Agent 65) exhibits potent fungicidal activity against Fusarium oxysporum f.sp.Fórmula:C29H29N3O2S2Cor e Forma:SolidPeso molecular:515.69Rustmicin
CAS:Rustmicin is a 14-membered macrolide identified as an inhibitor of plant pathogenic fungi.Fórmula:C21H32O6Cor e Forma:SolidPeso molecular:380.48SDH-IN-5
CAS:SDH-IN-5 (compound 7d), a potent inhibitor of succinate dehydrogenase (SDH) with an IC50 of 3.293 μM, additionally demonstrates antifungal efficacy, exhibitingFórmula:C16H19F2N3O2Cor e Forma:SolidPeso molecular:323.34Furalaxyl
CAS:Furalaxyl is an fungicide of acyl amino chiral.Fórmula:C17H19NO4Cor e Forma:SolidPeso molecular:301.34Vibunazole
CAS:Vibunazole is an antifungal agent.Fórmula:C15H20ClN3O2Cor e Forma:SolidPeso molecular:309.79CID-4785700
CAS:CID-4785700 is a potent pan-GTPase inhibitor that inhibits Rab7 and inhibits the fungal histone acetyltransferase Rtt109 that binds to Asf1 and Vps75Fórmula:C22H23ClFN3O3Pureza:98.16%Cor e Forma:SolidPeso molecular:431.89Ref: TM-T71740
1mg315,00€5mg873,00€10mg1.080,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.419,00€Fenpropimorph
CAS:Fenpropimorph is used as a small molecule fungicide.Fórmula:C20H33NOCor e Forma:SolidPeso molecular:303.48S-F24
CAS:S-F24 is a broad-spectrum antifungal agent that demonstrates potent inhibition of CYP3A4, with an IC50 of 0.4 μM.Fórmula:C25H27BrF2N6OCor e Forma:SolidPeso molecular:545.42Antifungal agent 35
CAS:Antifungal agent 35 is an effective antifungal agent that potentiates the antifungal activity of fluconazole against C. albicans.Fórmula:C26H27BrN4O4Cor e Forma:SolidPeso molecular:539.42Fenhexamid
CAS:Fenhexamid (Elevate), a sterol biosynthesis inhibitor, shows antifungal activity against the plant pathogenic fungus.Fórmula:C14H17Cl2NO2Pureza:99.56%Cor e Forma:SolidPeso molecular:302.20Chlorothalonil
CAS:Chlorothalonil (DAC 2787): Broad-spectrum, efficient, low-toxicity fungicide for fruits, vegetables, rice, wheat, cotton.Fórmula:C8Cl4N2Pureza:98.01% - 98.71%Cor e Forma:Colorless Crystals SolidPeso molecular:265.91DHMB
CAS:DHMB (2,3-Dihydroxy-4-Methoxybenzaldehyde) exerts protective effects on intestinal epithelial cells. DHMB exhibits anti-inflammatory and antifungal capacity.Fórmula:C8H8O4Pureza:99.57%Cor e Forma:SolidPeso molecular:168.15FBA-IN-1
CAS:FBA-IN-1 (2a11) is the first covalent, allosteric CaFBA inhibitor, effective against Azole-resistant strains with a MIC 80 of 1 μg/mL.
Fórmula:C15H13NOSePureza:98.79%Cor e Forma:SolidPeso molecular:302.23Rilopirox
CAS:Rilopirox is a synthetic fungicidal antimycotic with hydrophobic characteristics.Fórmula:C19H16ClNO4Pureza:99.17% - 99.72%Cor e Forma:SolidPeso molecular:357.79Flutrimazole
CAS:Flutrimazole: a dual-action imidazole with anti-inflammatory and antifungal effects; ideal for topical use due to limited skin penetration.Fórmula:C22H16F2N2Pureza:98.56%Cor e Forma:SolidPeso molecular:346.37ME1111
CAS:ME1111, a succinate dehydrogenase inhibitor of Trichophyton species, serves as an antifungal agent effective against dermatophytes.Fórmula:C12H14N2OPureza:99.91%Cor e Forma:SolidPeso molecular:202.25Ref: TM-T16033
1mg46,00€5mg94,00€1mL*10mM (DMSO)103,00€10mg140,00€25mg245,00€50mg338,00€100mg480,00€200mg622,00€PC945
CAS:PC945 (Opelconazole) is an antifungal compound that inhibits CYP51A/CYP51B and can be used to study fungal infections of the lungs.Fórmula:C38H37F3N6O3Pureza:98.89% - 99.37%Cor e Forma:SolidPeso molecular:682.73Ref: TM-T12376
1mg130,00€5mg313,00€1mL*10mM (DMSO)470,00€10mg505,00€25mg954,00€50mg1.468,00€100mg2.052,00€1-(6-Amino-3,5-difluoro-2-pyridinyl)-7-[3-[3-[[1-(6-amino-3,5-difluoro-2-pyridinyl)-3-carboxy-8-chloro-6-fluoro-1,4-dihydro-4-oxo-7- quinolinyl]amino]-2-hydroxypropoxy]-1-azetidinyl]-8-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
CAS:1-(6-Amino-3,5-difluoro-2-pyridinyl)-7-[3-[3-[[1-(6-amino-3,5-difluoro-2-pyridinyl)-3-carboxy-8-chloro-6-fluoro-1,4-dihydro-4-oxo-7-quinolinyl]amino]-2-hydroxypropoxy]-1-azetidinyl]-8-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid is a fluoroquinolone antibiotic, engineered through synthetic chemistry. It is derived from chemical sources involving complex organic synthesis, highlighting its intricate molecular architecture. Its mode of action is distinctive, as it inhibits bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication and transcription. This interference with bacterial DNA processes results in bactericidal effects, effectively eliminating susceptible bacterial strains.
Fórmula:C36H24Cl2F6N8O8Pureza:Min. 95%Peso molecular:881.52 g/molMicafungin FR-179642 impurity (acid)
CAS:Micafungin is an antifungal drug that inhibits the synthesis of ergosterol, a vital component of fungal cell membranes. It is a cyclic peptide with a lipophilic fatty acid chain that has been modified to allow penetration into cells. Micafungin is active against Candida and Aspergillus species and has shown activity against some strains of Cryptococcus neoformans. The MIC (minimum inhibitory concentration) for this drug ranges from 0.06 to 1 microgram/mL, depending on the bacterial strain being tested. Micafungin FR-179642 impurity (acid) is an impurity in micafungin that can be present as trace amounts in the final product and may contribute to hemolytic activity. This impurity is formed by hydrolysis during the synthesis process.Fórmula:C35H52N8O20SPureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:936.9 g/molPramiconazole
CAS:Pramiconazole (R126638), an oral antifungal, treats dermatophyte and yeast infections in seborrheic dermatitis.Fórmula:C35H39F2N7O4Pureza:98.1% - 98.59%Cor e Forma:SolidPeso molecular:659.73Phosphatase-IN-1
CAS:Phosphatase-IN-1 is a phosphatidic acid phosphatase (Pah) inhibitor with antifungal activity for the study of rice blast and ruderalia.Fórmula:C16H16Cl2FNO2Pureza:99.88%Cor e Forma:SolidPeso molecular:344.21Dihydropenicillin F potassium
CAS:Dihydropenicillin F potassium is a novel antibiotic compound, which is semisynthetic in nature, derived from the penicillin family. It is sourced through the modification of natural penicillins, bringing about enhanced stability and efficacy against certain resistant bacterial strains. The mode of action involves the inhibition of bacterial cell wall synthesis, primarily targeting the penicillin-binding proteins (PBPs). This disruption consequently leads to cell lysis and the eventual bacterial death.Fórmula:C14H22N2O4S•KPureza:Min. 95%Peso molecular:353.5 g/molOlorofim
CAS:Olorofim（F-901318）is a new selective antifungal compound that inhibits Aspergillus fumigatus DHODH (IC50: 44 nM). Cost-effective and quality-assured.Fórmula:C28H27FN6O2Pureza:99.28%Cor e Forma:SolidPeso molecular:498.55Antiproliferative agent-18
CAS:Compound 5k (Antiproliferative Agent-18) is an antiproliferative agent that exhibits moderate antibacterial and antifungal activities [1].Fórmula:C26H27FN2OSCor e Forma:SolidPeso molecular:434.57HDAC/HSP90-IN-3
CAS:HDAC/HSP90-IN-3, a dual inhibitor targeting fungal Hsp90 (IC50: 0.83 μM) & HDAC (IC50: 0.91 μM), counters azole-resistant C. albicans.Fórmula:C26H33N5O6Cor e Forma:SolidPeso molecular:511.57PF-184563
CAS:PF-184563 is an effective and selective non-peptide antagonist of the V1a receptor with oral activity, suitable for studying Raynaud's disease dysmenorrhoea.Fórmula:C21H23ClN6Pureza:99.67%Cor e Forma:SolidPeso molecular:394.9Verazine
CAS:(-)-Verazine is an antifungal agent isolated from the dried roots and rhizome of Veratrum maackii Regel, which induces DNA damage in the cerebellum and cerebralFórmula:C27H43NOCor e Forma:SolidPeso molecular:397.64Dihydroaltenuene B
CAS:Dihydroaltenuene B inhibits mushroom tyrosinase (IC50: 38.33µM) and binds His244, Met280, Gly281 via hydrogen bonds.Fórmula:C15H18O6Cor e Forma:SolidPeso molecular:294.3Antifungal agent 26
CAS:Pradimicin A derivative 26 exhibits antifungal, antiviral, and antiparasitic properties by attaching to d-mannose (Man)-rich glycans in pathogenic organisms [1Fórmula:C40H45N3O18Cor e Forma:SolidPeso molecular:855.796-Chloro-7-deazapurine-β-D-riboside
CAS:6-Chloro-7-deazapurine-β-D-riboside shows antifungal activity.Fórmula:C11H12ClN3O4Pureza:98.26%Cor e Forma:SolidPeso molecular:285.68APX2039
CAS:APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activityFórmula:C20H15FN4O2Pureza:98.72% - 99.07%Cor e Forma:SolidPeso molecular:362.36Ref: TM-T61355
1mg116,00€5mg260,00€1mL*10mM (DMSO)288,00€10mg389,00€25mg687,00€50mg982,00€100mg1.350,00€200mg1.783,00€Y18501
CAS:Y18501, an oxysterol-binding protein (OSBPI) inhibitor structurally akin to Oxathiapiprolin, demonstrates potent inhibition against Phytophthora spp.Fórmula:C27H26F2N6O2SCor e Forma:SolidPeso molecular:536.6Antifungal agent 49
CAS:Antifungal agent 49 (Example 112) exhibits activity against Cryptococcus neoformans, demonstrating a minimum inhibitory concentration (MIC) of 49 μM [1].Fórmula:C15H12O4Cor e Forma:SolidPeso molecular:256.25APX001
CAS:APX001 is a prodrug of APX-001A. APX001 is the first-in-class inhibitor of the fungal protein Gwt1.Fórmula:C22H21N4O6PPureza:98%Cor e Forma:SolidPeso molecular:468.4Orysastrobin
CAS:Orysastrobin, a "quinone outside inhibitor" (QoI) fungicide, demonstrates outstanding efficacy in controlling rice leaf and panicle blast as well as sheathFórmula:C18H25N5O5Cor e Forma:SolidPeso molecular:391.422-C-methylene-myo-inositol oxide
CAS:2-C-Methylene-myo-inositol oxide (NSC 45109), an inositol derivative, promotes pseudohyphal growth in Saccharomyces species [1].Fórmula:C7H12O6Cor e Forma:SolidPeso molecular:192.17Loflucarban
CAS:Loflucarban (Fluonilid) is an antimycotic compoud.Fórmula:C13H9Cl2FN2SPureza:98.08% - 98.15%Cor e Forma:SolidPeso molecular:315.19Antifungal agent 48
CAS:Antifungal agent 48 (Example 308), active against Cryptococcus neoformans, exhibits a minimum inhibitory concentration (MIC) value of 11 μM [1].Fórmula:C13H10O4SCor e Forma:SolidPeso molecular:262.28Antifungal agent 66
CAS:Antifungal agent 66 (compound 10) exhibits broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia and significant inhibitory effects onFórmula:C19H25ClO6Cor e Forma:SolidPeso molecular:384.85Chitin synthase inhibitor 14
CAS:Chitin Synthase Inhibitor 14 (compound 4n), a potent chitin synthase (CHS) inhibitor, exhibits antifungal activity and is effective against drug-resistantFórmula:C25H26ClN5O5Cor e Forma:SolidPeso molecular:511.96Icofungipen
CAS:Icofungipen is an oral antifungals with active against Candida species.Fórmula:C7H11NO2Pureza:98%Cor e Forma:SolidPeso molecular:141.17VT-1598
CAS:VT-1598 is a novel, selective, orally active fungal CYP51 inhibitor. VT-1598 exhibits antifungal effects against Candida albicans.Fórmula:C31H20F4N6O2Cor e Forma:SolidPeso molecular:584.52FT895
CAS:FT895 is a selective and potent HDAC11 inhibitor with antifungal and antitumor activity that inhibits HDAC11 expression and limits EV71 replication in vitro.Fórmula:C16H15F3N4O2Pureza:98.95% - >99.99%Cor e Forma:SolidPeso molecular:352.31Ref: TM-T11329
1mg92,00€5mg219,00€1mL*10mM (DMSO)241,00€10mg339,00€25mg570,00€50mg795,00€100mg1.108,00€
