Antifúngicos
Os antifúngicos são compostos especificamente projetados para interromper, prevenir e eliminar o crescimento de fungos. Nesta categoria, você encontrará uma ampla variedade de agentes antifúngicos essenciais para pesquisa e aplicações terapêuticas. Esses compostos são cruciais no tratamento de infecções fúngicas e na prevenção de sua recorrência, tornando-os ferramentas vitais tanto em ambientes médicos quanto agrícolas. Pesquisadores e profissionais de saúde podem explorar inúmeros antifúngicos para entender seus mecanismos, otimizar sua eficácia e desenvolver novos tratamentos para combater cepas fúngicas resistentes. A extensa seleção de antifúngicos apoia os avanços contínuos na pesquisa sobre fungos e no desenvolvimento de terapias antifúngicas eficazes.
Foram encontrados 835 produtos de "Antifúngicos"
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APX001
CAS:<p>APX001 is a prodrug of APX-001A. APX001 is the first-in-class inhibitor of the fungal protein Gwt1.</p>Fórmula:C22H21N4O6PPureza:98%Cor e Forma:SolidPeso molecular:468.4VT-1598
CAS:<p>VT-1598 is a novel, selective, orally active fungal CYP51 inhibitor. VT-1598 exhibits antifungal effects against Candida albicans.</p>Fórmula:C31H20F4N6O2Cor e Forma:SolidPeso molecular:584.52Antifungal agent 26
CAS:<p>Pradimicin A derivative 26 exhibits antifungal, antiviral, and antiparasitic properties by attaching to d-mannose (Man)-rich glycans in pathogenic organisms [1</p>Fórmula:C40H45N3O18Cor e Forma:SolidPeso molecular:855.79Loflucarban
CAS:<p>Loflucarban (Fluonilid) is an antimycotic compoud.</p>Fórmula:C13H9Cl2FN2SPureza:98.08% - 98.15%Cor e Forma:SolidPeso molecular:315.19TMV-IN-5
CAS:<p>TMV-IN-5 (compound 1a) serves as an antiviral/antifungal agent, specifically targeting and inhibiting the assembly of the tobacco mosaic virus (TMV) by binding</p>Fórmula:C22H23N3SCor e Forma:SolidPeso molecular:361.5Antifungal agent 66
CAS:<p>Antifungal agent 66 (compound 10) exhibits broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia and significant inhibitory effects on</p>Fórmula:C19H25ClO6Cor e Forma:SolidPeso molecular:384.85Antifungal agent 48
CAS:<p>Antifungal agent 48 (Example 308), active against Cryptococcus neoformans, exhibits a minimum inhibitory concentration (MIC) value of 11 μM [1].</p>Fórmula:C13H10O4SCor e Forma:SolidPeso molecular:262.28Eucalyptacid A
CAS:<p>Eucalyptacid A, a metabolite with antifungal properties, demonstrates efficacy against Alternaria solani, displaying minimum inhibitory concentrations (MIC)</p>Fórmula:C17H32O5Cor e Forma:SolidPeso molecular:316.43Prochloraz manganese
CAS:<p>Prochloraz manganese, an antifungal agent utilized in the agricultural sectors [1], serves to protect crops by inhibiting fungal growth.</p>Fórmula:C60H64Cl14MnN12O8Cor e Forma:SolidPeso molecular:1632.51MoTPS1-IN-1
CAS:<p>MoTPS1-IN-1 is a potent MoTPS1 inhibitor with antifungal anti-inflammatory activity that acts through interaction with Glu396 study ulcerative colitis.</p>Fórmula:C23H27F3N2O4Pureza:99.28%Cor e Forma:SoildPeso molecular:452.47Verazine
CAS:<p>(-)-Verazine is an antifungal agent isolated from the dried roots and rhizome of Veratrum maackii Regel, which induces DNA damage in the cerebellum and cerebral</p>Fórmula:C27H43NOCor e Forma:SolidPeso molecular:397.642-Dodecanol
CAS:<p>2-Dodecanol suppresses both hyphal development and SIR2 gene expression in Candida albicans [1].</p>Fórmula:C12H26OCor e Forma:SolidPeso molecular:186.33Antifungal agent 49
CAS:<p>Antifungal agent 49 (Example 112) exhibits activity against Cryptococcus neoformans, demonstrating a minimum inhibitory concentration (MIC) of 49 μM [1].</p>Fórmula:C15H12O4Cor e Forma:SolidPeso molecular:256.25APX2039
CAS:<p>APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activity</p>Fórmula:C20H15FN4O2Pureza:98.72% - 99.07%Cor e Forma:SolidPeso molecular:362.36Fenpropidin
CAS:<p>Fenpropidin (Ro-12-3049), a fungicide, is a specific inhibitor of sterol 14-reductase and biosynthesis.</p>Fórmula:C19H31NPureza:98.58% - 99.54%Cor e Forma:SolidPeso molecular:273.46Y18501
CAS:<p>Y18501, an oxysterol-binding protein (OSBPI) inhibitor structurally akin to Oxathiapiprolin, demonstrates potent inhibition against Phytophthora spp.</p>Fórmula:C27H26F2N6O2SCor e Forma:SolidPeso molecular:536.6Dihydroaltenuene B
CAS:<p>Dihydroaltenuene B inhibits mushroom tyrosinase (IC50: 38.33µM) and binds His244, Met280, Gly281 via hydrogen bonds.</p>Fórmula:C15H18O6Cor e Forma:SolidPeso molecular:294.3HDAC/HSP90-IN-3
CAS:<p>HDAC/HSP90-IN-3, a dual inhibitor targeting fungal Hsp90 (IC50: 0.83 μM) & HDAC (IC50: 0.91 μM), counters azole-resistant C. albicans.</p>Fórmula:C26H33N5O6Cor e Forma:SolidPeso molecular:511.57Antiproliferative agent-18
CAS:<p>Compound 5k (Antiproliferative Agent-18) is an antiproliferative agent that exhibits moderate antibacterial and antifungal activities [1].</p>Fórmula:C26H27FN2OSCor e Forma:SolidPeso molecular:434.57Antifungal agent 77
CAS:<p>Antifungal agent 77 (Compound 13h) exhibits not only antifungal properties, but also effective insecticidal activity against Mythimna separata, Helicoverpa</p>Fórmula:C21H18FN5O2Cor e Forma:SolidPeso molecular:391.4Chitin synthase inhibitor 14
CAS:<p>Chitin Synthase Inhibitor 14 (compound 4n), a potent chitin synthase (CHS) inhibitor, exhibits antifungal activity and is effective against drug-resistant</p>Fórmula:C25H26ClN5O5Cor e Forma:SolidPeso molecular:511.96Orysastrobin
CAS:<p>Orysastrobin, a "quinone outside inhibitor" (QoI) fungicide, demonstrates outstanding efficacy in controlling rice leaf and panicle blast as well as sheath</p>Fórmula:C18H25N5O5Cor e Forma:SolidPeso molecular:391.42Zoxamide
CAS:<p>Zoxamide (RH-7281) is an oomycete-specific fungicide that impedes nuclear division in Phytophthora capsici germlings and disrupts the microtubule cytoskeleton [</p>Fórmula:C14H16Cl3NO2Cor e Forma:SolidPeso molecular:336.64Inz-5
CAS:<p>Inz-5 is a fungal-selective inhibitor of mitochondrial cytochrome bc1. Inz-5 impairs fungal virulence. It also prevents the evolution of drug resistance.</p>Fórmula:C18H14F4N6Cor e Forma:SolidPeso molecular:390.34Econazole
CAS:<p>Econazole is an imidazole antifungal agent with action on fungal cell membrane disruption and is used for treating fungal skin infections like athlete's foot and ringworm.</p>Fórmula:C18H15Cl3N2OPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:381.68 g/molFengycin
CAS:<p>Fengycin is a cyclic lipopeptide from Bacillus subtilis acts as a biosurfactant and antifungal. As a fungicide, it has a mode of action that involves the formation of ion channels in the fungal lipid membrane, leading to membrane leakage This activity is negatively correlated to cholesterol levels, and may explain why mammalian cells, with higher cholesterol present, are not sensitive to fengycin.</p>Fórmula:C72H110N12O20Pureza:Min. 90 Area-%Cor e Forma:PowderPeso molecular:1,463.71 g/mol2,4′-Dichloroacetanilide
CAS:<p>2,4′-Dichloroacetanilide (2-chloro-N-(4-chlorophenyl)acetamide) has antifungal activity and inhibits T. asteroides with a MIC value of 6.25 μg/mL.</p>Fórmula:C8H7Cl2NOPureza:99.36%Cor e Forma:SolidPeso molecular:204.05Fosmanogepix
CAS:<p>Fosmanogepix (APX001) is a broad-spectrum oral antifungal that targets Gwt1 enzyme, transforming into active APX001A in the body.</p>Fórmula:C22H21N4O6PPureza:98%Cor e Forma:SolidPeso molecular:468.40Antifungal agent 43
<p>Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.</p>Fórmula:C24H26N4Se2Cor e Forma:SolidPeso molecular:528.41CDA-IN-4
CAS:<p>CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.</p>Fórmula:C10H9BrN4O2SCor e Forma:SolidPeso molecular:329.17HDAC-IN-87
CAS:<p>HDAC-IN-87 (Compound XII6) is a non-selective HDAC inhibitor with pIC50 values of 6.9 for HDAC4 and 5.8 for HDAC6. It exhibits fungicidal activity against P. sorghi and P. pachyrhizi. The acute oral LD50 in both male and female rats is greater than 500 mg/kg.</p>Fórmula:C13H7F5N4O2SCor e Forma:SolidPeso molecular:378.277Chitin synthase inhibitor 9
<p>CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.</p>Fórmula:C24H25N3O6Cor e Forma:SolidPeso molecular:451.47Antifungal agent 28
<p>Antifungal 28 disrupts Candida, hits fluconazole-resistant strains, and inhibits biofilms.</p>Fórmula:C22H29N5OSCor e Forma:SolidPeso molecular:411.56AnCDA-IN-1
CAS:<p>AnCDA-IN-1 (Compound J075-4187) is an inhibitor of chitin deacetylase (CDA) exhibiting antifungal properties. It possesses an IC50 of 4.24 μM against A. nidulans AnCDA. The compound demonstrates a minimum inhibitory concentration (MIC) of 260 μg/mL and a minimum fungicidal concentration (MFC) of 520 μg/mL for food spoilage fungi and plant pathogenic fungi. AnCDA-IN-1 is applicable for research in the antifungal domain.</p>Fórmula:C16H13ClN4O2Cor e Forma:SolidPeso molecular:328.753Antifungal agent 17
<p>Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).</p>Fórmula:C18H16Br2O2Cor e Forma:SolidPeso molecular:424.13Antifungal agent 100
CAS:<p>Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].</p>Fórmula:C23H21N3O4SCor e Forma:SolidPeso molecular:435.5Antibacterial agent 188
CAS:<p>Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].</p>Fórmula:C12H10N4SCor e Forma:SolidPeso molecular:242.3HSP90-IN-9
<p>HSP90-IN-9: potent HSP90 inhibitor, dose-dependent fungicide, impedes biofilm/morphology with FLC, reverses FLC resistance.</p>Cor e Forma:SolidIsopyrazam
CAS:<p>Isopyrazam, a plant protection product, exhibits potent antifungal activity. When applied to crops, it effectively inhibits the growth of various plant pathogenic fungi, significantly enhancing both the yield and quality of the crops. This compound demonstrates exceptional disease resistance capabilities in agricultural applications.</p>Fórmula:C20H23F2N3OCor e Forma:SolidPeso molecular:359.41Antifungal agent 127
CAS:<p>Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.</p>Fórmula:C13H12ClN3OCor e Forma:SolidPeso molecular:261.707Antifungal agent 125
CAS:<p>Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.</p>Fórmula:C13H10BrNO4SCor e Forma:SolidPeso molecular:356.192Hyalodendrin
CAS:<p>Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.</p>Fórmula:C14H16N2O3S2Cor e Forma:SolidPeso molecular:324.42WQ3810 TFA
<p>WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity of</p>Fórmula:C24H23F6N5O5Pureza:99.52%Cor e Forma:SoildPeso molecular:575.46CDA-IN-3
CAS:<p>CDA-IN-3 (NCDI) is a chitin deacetylase (CDA) inhibitor with antiparasitic properties. It disrupts chitin metabolism in nematodes, increasing ROS levels within these organisms and causing cellular damage. CDA-IN-3 significantly inhibits all developmental stages of Caenorhabditis elegans and can be utilized in research focused on anti-infective applications.</p>Fórmula:C16H27N3O3S2Cor e Forma:SolidPeso molecular:373.534CDA-IN-2
CAS:<p>CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.</p>Fórmula:C17H16N2O7Cor e Forma:SolidPeso molecular:360.318CDA-IN-1
CAS:<p>CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal activity. By inhibiting fungal CDA activity, it activates plant immune responses and leads to the accumulation of reactive oxygen species (ROS), hindering fungal growth. At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% on P. xanthii's PxCDA1 and 74.5% on PxCDA2. CDA-IN-1 is applicable in research on fungal plant diseases, such as cucumber powdery mildew and tomato gray mold.</p>Fórmula:C15H14N2O6Cor e Forma:SolidPeso molecular:318.281Chitin synthase inhibitor 8
<p>Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infections</p>Fórmula:C23H23N3O5Cor e Forma:SolidPeso molecular:421.45Furametpyr
CAS:<p>Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.</p>Fórmula:C17H20ClN3O2Pureza:98%Cor e Forma:SolidPeso molecular:333.81Antifungal agent 12
<p>Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.</p>Fórmula:C20H16F3N7O2S2Cor e Forma:SolidPeso molecular:507.51Antifungal agent 11
<p>Antifungal agent 11 has a good antifungal effect.</p>Fórmula:C21H19F2N7O3S2Cor e Forma:SolidPeso molecular:519.55
