Antifúngicos
Os antifúngicos são compostos especificamente projetados para interromper, prevenir e eliminar o crescimento de fungos. Nesta categoria, você encontrará uma ampla variedade de agentes antifúngicos essenciais para pesquisa e aplicações terapêuticas. Esses compostos são cruciais no tratamento de infecções fúngicas e na prevenção de sua recorrência, tornando-os ferramentas vitais tanto em ambientes médicos quanto agrícolas. Pesquisadores e profissionais de saúde podem explorar inúmeros antifúngicos para entender seus mecanismos, otimizar sua eficácia e desenvolver novos tratamentos para combater cepas fúngicas resistentes. A extensa seleção de antifúngicos apoia os avanços contínuos na pesquisa sobre fungos e no desenvolvimento de terapias antifúngicas eficazes.
Foram encontrados 908 produtos de "Antifúngicos"
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Byssochlamic Acid
CAS:Byssochlamic acid, a mycotoxin identified in the agricultural fungal pathogen B. fulva, exhibits lethality in mice with an LD50 of 94 mg/kg.Fórmula:C18H20O6Cor e Forma:SolidPeso molecular:332.4Antifungal agent 50
CAS:Antifungal agent 50 exhibits minimum inhibitory concentrations (MICs) ranging from less than 0.063 to 1 μg/mL [1].Fórmula:C25H20ClN5O2SCor e Forma:SolidPeso molecular:489.98Eucalyptacid A
CAS:Eucalyptacid A, a metabolite with antifungal properties, demonstrates efficacy against Alternaria solani, displaying minimum inhibitory concentrations (MIC)Fórmula:C17H32O5Cor e Forma:SolidPeso molecular:316.43FR194738 free base
CAS:FR194738 free base inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.Fórmula:C27H37NO2SPureza:99.13%Cor e Forma:SolidPeso molecular:439.65Ref: TM-T11321
1mg75,00€5mg164,00€1mL*10mM (DMSO)177,00€10mg234,00€25mg353,00€50mg487,00€100mg637,00€Fenpropidin
CAS:Fenpropidin (Ro-12-3049), a fungicide, is a specific inhibitor of sterol 14-reductase and biosynthesis.Fórmula:C19H31NPureza:98.58% - 99.54%Cor e Forma:SolidPeso molecular:273.46Inz-1
CAS:Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human.Fórmula:C16H14N2O2Pureza:99.55% - 99.88%Cor e Forma:SolidPeso molecular:266.29Methyl 3,4-dimethoxycinnamate
CAS:Methyl 3,4-dimethoxycinnamate impedes uredospore germination and concurrently inhibits global DNA methylation in Hep3B cells [1] [2].Fórmula:C12H14O4Cor e Forma:SolidPeso molecular:222.24Antifungal agent 77
CAS:Antifungal agent 77 (Compound 13h) exhibits not only antifungal properties, but also effective insecticidal activity against Mythimna separata, HelicoverpaFórmula:C21H18FN5O2Cor e Forma:SolidPeso molecular:391.4N,O-Diacetyltyramine
CAS:N,O-Diacetyltyramine, isolated from the actinomycete Pseudonocardia endophytica VUK-10, exhibits both antibacterial activity against Gram-positive and Gram-negative bacteria, alongside fungi, and demonstrates cytotoxicity towards MDA-MB-231, HeLa, MCF-7, and OAW-42 cells [1].Fórmula:C12H15NO3Cor e Forma:SolidPeso molecular:221.25Phenamacril
CAS:Phenamacril (JS39919) is acyanoacrylate fungicide, has powerful inhibition against Fusarium species, especially to Fusarium graminearum.Fórmula:C12H12N2O2Pureza:99.52%Cor e Forma:SolidPeso molecular:216.24Ref: TM-T24214
1mg138,00€1mL*10mM (DMSO)259,00€5mg303,00€10mg447,00€25mg713,00€50mg1.018,00€100mg1.369,00€500mg2.673,00€Antifungal agent 24
CAS:Antifungal agent 24 (Compound 6) is an antifungal agent that inhibits Candida albicans (MIC: 0.03 μg/ml).Fórmula:C24H18F2N4OCor e Forma:SolidPeso molecular:416.42Laxifloran
CAS:Laxifloran possesses antibacterial and antifungal properties.Fórmula:C17H18O5Cor e Forma:SolidPeso molecular:302.322-Dodecanol
CAS:2-Dodecanol suppresses both hyphal development and SIR2 gene expression in Candida albicans [1].Fórmula:C12H26OCor e Forma:SolidPeso molecular:186.33Antiproliferative agent-33
CAS:Antiproliferative Agent-33 (Compound 2g) serves as an anti-proliferative, antifungal, and antibacterial agent, effectively inhibiting the proliferation of MDA-Fórmula:C21H26N2OCor e Forma:SolidPeso molecular:322.44TMTD (Tetramethylthiuram disulfide)
CAS:TMTD (Tetramethylthiuram disulfide) reduces the growth performance of chickens by reducing liver index, while increasing kidney, heart and spleen index. In addition, TMTD also induces tibial chondrodysplasia (TD) by regulating the expression of VEGF, HIF-1α and WNT4. As a super accelerator in rubber processing, TMTD plays an important role in the low-temperature vulcanization process and is a key pesticide in agriculture.Fórmula:C6H12N2S4Cor e Forma:SolidPeso molecular:240.43Azaconazole
CAS:Azaconazole, an agricultural fungicide, is used for controlling powdery mildew on crops and bean rust.Fórmula:C12H11Cl2N3O2Cor e Forma:SolidPeso molecular:300.144′-DTMP
CAS:4′-DTMP (4-Demethyltrimethoprim) is a DHFR inhibitor with antimicrobial activity against Escherichia coli.Fórmula:C13H16N4O3Pureza:98%Cor e Forma:SolidPeso molecular:276.29TMV-IN-5
CAS:TMV-IN-5 (compound 1a) serves as an antiviral/antifungal agent, specifically targeting and inhibiting the assembly of the tobacco mosaic virus (TMV) by bindingFórmula:C22H23N3SCor e Forma:SolidPeso molecular:361.5Alteconazole
CAS:Alteconazole is an antifungal drug.Fórmula:C17H12Cl3N3OPureza:98%Cor e Forma:SolidPeso molecular:380.66Prochloraz manganese
CAS:Prochloraz manganese, an antifungal agent utilized in the agricultural sectors [1], serves to protect crops by inhibiting fungal growth.Fórmula:C60H64Cl14MnN12O8Cor e Forma:SolidPeso molecular:1632.51MoTPS1-IN-1
CAS:MoTPS1-IN-1 is a potent MoTPS1 inhibitor with antifungal anti-inflammatory activity that acts through interaction with Glu396 study ulcerative colitis.Fórmula:C23H27F3N2O4Pureza:99.76%Cor e Forma:SoildPeso molecular:452.47Zoxamide
CAS:Zoxamide (RH-7281) is an oomycete-specific fungicide that impedes nuclear division in Phytophthora capsici germlings and disrupts the microtubule cytoskeleton [Fórmula:C14H16Cl3NO2Cor e Forma:SolidPeso molecular:336.64Inz-5
CAS:Inz-5 is a fungal-selective inhibitor of mitochondrial cytochrome bc1. Inz-5 impairs fungal virulence. It also prevents the evolution of drug resistance.Fórmula:C18H14F4N6Cor e Forma:SolidPeso molecular:390.342,4′-Dichloroacetanilide
CAS:2,4′-Dichloroacetanilide (2-chloro-N-(4-chlorophenyl)acetamide) has antifungal activity and inhibits T. asteroides with a MIC value of 6.25 μg/mL.Fórmula:C8H7Cl2NOPureza:99.36%Cor e Forma:SolidPeso molecular:204.05Fengycin
CAS:Fengycin is a cyclic lipopeptide from Bacillus subtilis acts as a biosurfactant and antifungal. As a fungicide, it has a mode of action that involves the formation of ion channels in the fungal lipid membrane, leading to membrane leakage This activity is negatively correlated to cholesterol levels, and may explain why mammalian cells, with higher cholesterol present, are not sensitive to fengycin.Fórmula:C72H110N12O20Pureza:Min. 90 Area-%Cor e Forma:PowderPeso molecular:1,463.71 g/molEconazole
CAS:Econazole is an imidazole antifungal agent with action on fungal cell membrane disruption and is used for treating fungal skin infections like athlete's foot and ringworm.Fórmula:C18H15Cl3N2OPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:381.68 g/molAntifungal agent 43
Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.Fórmula:C24H26N4Se2Cor e Forma:SolidPeso molecular:528.41Antifungal agent 125
CAS:Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.Fórmula:C13H10BrNO4SCor e Forma:SolidPeso molecular:356.192CDA-IN-2
CAS:CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.Fórmula:C17H16N2O7Cor e Forma:SolidPeso molecular:360.318Furametpyr
CAS:Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.Fórmula:C17H20ClN3O2Pureza:98%Cor e Forma:SolidPeso molecular:333.81N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide
N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor as well as antifungal agent [1].Fórmula:C11H9FN4OCor e Forma:SolidPeso molecular:232.21A25822B
CAS:A25822B is an antifungal agent.Fórmula:C28H45NOPureza:98%Cor e Forma:SolidPeso molecular:411.66Antifungal agent 40
Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.Fórmula:C22H20Cl2N4SeCor e Forma:SolidPeso molecular:490.29Chitin synthase inhibitor 11
Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.Fórmula:C24H24N4O8Cor e Forma:SolidPeso molecular:496.47Yck2-IN-1
CAS:Yck2-IN-1 (Compound 2a) is an inhibitor of the fungus Candida albicans Yck2. It has an IC50 of approximately 80 nM for Yck2 and an MIC80 of 12.5 µM for C. albicans, demonstrating good metabolic stability [66% remaining in mouse liver microsomes]. In a mouse model with drug-resistant Candida, Yck2-IN-1 significantly reduced fungal load in the kidneys. Yck2-IN-1 shows potential for research in antifungal infection treatments.Fórmula:C19H11FN4Cor e Forma:SolidPeso molecular:314.316Tenellin
CAS:Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.Fórmula:C21H23NO5Cor e Forma:SolidPeso molecular:369.41SARS-CoV-2 Mpro-IN-34
SARS-CoV-2 Mpro-IN-34 (Compound 26) acts as an inhibitor of SARS-CoV-2 Mpro with an IC50 of 6 nM. It also inhibits OC43 Mpro, demonstrating an IC50 of 33 nM. Furthermore, this compound exhibits antiviral activity in Vero E6 cells infected with SARS-CoV-2, with an EC50 of 0.103 μM.Fórmula:C30H37Cl2N5O3Cor e Forma:SolidPeso molecular:586.55Fosmanogepix
CAS:Fosmanogepix (APX001) is a broad-spectrum oral antifungal that targets Gwt1 enzyme, transforming into active APX001A in the body.Fórmula:C22H21N4O6PPureza:98%Cor e Forma:SolidPeso molecular:468.40Antifungal agent 100
CAS:Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].Fórmula:C23H21N3O4SCor e Forma:SolidPeso molecular:435.5Succinate dehydrogenase-IN-8
CAS:Succinate dehydrogenase-IN-8 (compound i19) is a potent inhibitor of succinate dehydrogenase (SDH). This indanoyl amino acid derivative demonstrates strong antifungal activity in vitro against Rhizoctonia solani (EC50 = 0.1843 mg/L), Botrytis cinerea (EC50 = 0.4829 mg/L), and Sclerotinia sclerotiorum (EC50 = 0.1349 mg/L).Fórmula:C22H19Cl2F2N5O2Cor e Forma:SolidPeso molecular:494.32Antibacterial agent 188
CAS:Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].Fórmula:C12H10N4SCor e Forma:SolidPeso molecular:242.3Antifungal agent 16
Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.Fórmula:C27H21N5O2SCor e Forma:SolidPeso molecular:479.55WQ3810 TFA
WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity ofFórmula:C24H23F6N5O5Pureza:99.52%Cor e Forma:SoildPeso molecular:575.46Antifungal agent 28
Antifungal 28 disrupts Candida, hits fluconazole-resistant strains, and inhibits biofilms.Fórmula:C22H29N5OSCor e Forma:SolidPeso molecular:411.56Antifungal agent 19
Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).Fórmula:C19H18F4O2Cor e Forma:SolidPeso molecular:354.34Nikkomycin Z
CAS:Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,Fórmula:C20H25N5O10Pureza:98%Cor e Forma:SolidPeso molecular:495.44PKR-IN-1
CAS:PKR-IN-1 (Compound 5s) is a pyruvate kinase (PK) inhibitor with antifungal properties, exhibiting an EC50 of 0.21 μg/mL against Rhizoctonia solani (R. solani).Fórmula:C9HCl5N4OS2Cor e Forma:SolidPeso molecular:422.525Hyalodendrin
CAS:Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.Fórmula:C14H16N2O3S2Cor e Forma:SolidPeso molecular:324.42CDA-IN-4
CAS:CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.Fórmula:C10H9BrN4O2SCor e Forma:SolidPeso molecular:329.17Antifungal agent 11
Antifungal agent 11 has a good antifungal effect.Fórmula:C21H19F2N7O3S2Cor e Forma:SolidPeso molecular:519.55
