Antifúngicos
Os antifúngicos são compostos especificamente projetados para interromper, prevenir e eliminar o crescimento de fungos. Nesta categoria, você encontrará uma ampla variedade de agentes antifúngicos essenciais para pesquisa e aplicações terapêuticas. Esses compostos são cruciais no tratamento de infecções fúngicas e na prevenção de sua recorrência, tornando-os ferramentas vitais tanto em ambientes médicos quanto agrícolas. Pesquisadores e profissionais de saúde podem explorar inúmeros antifúngicos para entender seus mecanismos, otimizar sua eficácia e desenvolver novos tratamentos para combater cepas fúngicas resistentes. A extensa seleção de antifúngicos apoia os avanços contínuos na pesquisa sobre fungos e no desenvolvimento de terapias antifúngicas eficazes.
Foram encontrados 871 produtos de "Antifúngicos"
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AnCDA-IN-1
CAS:<p>AnCDA-IN-1 (Compound J075-4187) is an inhibitor of chitin deacetylase (CDA) exhibiting antifungal properties. It possesses an IC50 of 4.24 μM against A. nidulans AnCDA. The compound demonstrates a minimum inhibitory concentration (MIC) of 260 μg/mL and a minimum fungicidal concentration (MFC) of 520 μg/mL for food spoilage fungi and plant pathogenic fungi. AnCDA-IN-1 is applicable for research in the antifungal domain.</p>Fórmula:C16H13ClN4O2Cor e Forma:SolidPeso molecular:328.753HSP90-IN-9
HSP90-IN-9: potent HSP90 inhibitor, dose-dependent fungicide, impedes biofilm/morphology with FLC, reverses FLC resistance.Cor e Forma:SolidComplex III-IN-2
<p>Complex III-IN-2 inhibits complex III, with antifungal EC50: 29.31 mg/L vs R. solani, 29.98 mg/L vs S. sclerotiorum.</p>Fórmula:C15H21ClN2O2SCor e Forma:SolidPeso molecular:328.86Chitin synthase inhibitor 5
Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.Fórmula:C23H22BrN3O5Cor e Forma:SolidPeso molecular:500.34Isopyrazam
CAS:Isopyrazam, a plant protection product, exhibits potent antifungal activity. When applied to crops, it effectively inhibits the growth of various plant pathogenic fungi, significantly enhancing both the yield and quality of the crops. This compound demonstrates exceptional disease resistance capabilities in agricultural applications.Fórmula:C20H23F2N3OCor e Forma:SolidPeso molecular:359.41Antibacterial agent 188
CAS:Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].Fórmula:C12H10N4SCor e Forma:SolidPeso molecular:242.3Wikstrol A
CAS:Wikstrol A: antifungal, anti-mitotic, anti-HIV agent with various IC50/MDC values (67.8-131 µM) and deforms P. oryzae mycelia.Fórmula:C30H22O10Cor e Forma:SolidPeso molecular:542.49Chitin synthase inhibitor 8
Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infectionsFórmula:C23H23N3O5Cor e Forma:SolidPeso molecular:421.45Chitin synthase inhibitor 9
CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.Fórmula:C24H25N3O6Cor e Forma:SolidPeso molecular:451.47Antifungal agent 12
Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.Fórmula:C20H16F3N7O2S2Cor e Forma:SolidPeso molecular:507.51SARS-CoV-2 Mpro-IN-34
SARS-CoV-2 Mpro-IN-34 (Compound 26) acts as an inhibitor of SARS-CoV-2 Mpro with an IC50 of 6 nM. It also inhibits OC43 Mpro, demonstrating an IC50 of 33 nM. Furthermore, this compound exhibits antiviral activity in Vero E6 cells infected with SARS-CoV-2, with an EC50 of 0.103 μM.Fórmula:C30H37Cl2N5O3Cor e Forma:SolidPeso molecular:586.55Griseofulvic Acid
CAS:<p>Griseofulvic Acid ((±)-Griseofulvic acid) is a metabolite of the antifungal agent Griseofulvin. It induces protein aggregation and tubulin polymerization in cell-free assays.</p>Fórmula:C16H15ClO6Peso molecular:338.74Antifungal agent 42
Antifungal 42 blocks biofilm formation and inhibits C.albicans' CYP51.Fórmula:C22H20Cl2N4Se2Cor e Forma:SolidPeso molecular:569.25A25822B
CAS:A25822B is an antifungal agent.Fórmula:C28H45NOPureza:98%Cor e Forma:SolidPeso molecular:411.66Antifungal agent 39
CAS:Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.Fórmula:C23H22ClN3O5Cor e Forma:SolidPeso molecular:455.89D75-4590
CAS:<p>D75-4590, a β-1,6-Glucan synthetase inhibitor, combats fungal infections by targeting cell walls.</p>Fórmula:C21H27N5Pureza:98.56% - 98.85%Cor e Forma:SolidPeso molecular:349.474-Hydroxyvoriconazole
CAS:<p>Metabolite of voriconazole; sterol 14?-demethylase inhibitor</p>Pureza:Min. 95%Tetraconazole
CAS:Tetraconazole is an agent of pesticides.Fórmula:C13H11Cl2F4N3OCor e Forma:Liquid ViscousPeso molecular:372.142,7-Dihydroxynaphthalene
CAS:2,7-Dihydroxynaphthalene is a useful organic compound for research related to life sciences. The catalog number is T67338 and the CAS number is 582-17-2.Fórmula:C10H8O2Cor e Forma:SolidPeso molecular:160.17Rhizocticin A
CAS:<p>Rhizocticin A is a potential inhibitor of threonine synthase.</p>Fórmula:C11H22N5O6PPureza:98%Cor e Forma:SolidPeso molecular:351.3Amphotericin A
CAS:<p>Amphotericin A is a polyene macrolide antibiotic, which is derived primarily from the soil bacterium *Streptomyces nodosus*. This compound functions by binding to ergosterol, an essential component of fungal cell membranes. This binding creates pores in the membrane, increasing its permeability and ultimately leading to cell death. Unlike its more widely used counterpart Amphotericin B, Amphotericin A is less frequently utilized but is critical in the study and understanding of antifungal activity.</p>Fórmula:C47H75NO17Pureza:Min. 95%Peso molecular:926.09 g/mol
