Antifúngicos
Os antifúngicos são compostos especificamente projetados para interromper, prevenir e eliminar o crescimento de fungos. Nesta categoria, você encontrará uma ampla variedade de agentes antifúngicos essenciais para pesquisa e aplicações terapêuticas. Esses compostos são cruciais no tratamento de infecções fúngicas e na prevenção de sua recorrência, tornando-os ferramentas vitais tanto em ambientes médicos quanto agrícolas. Pesquisadores e profissionais de saúde podem explorar inúmeros antifúngicos para entender seus mecanismos, otimizar sua eficácia e desenvolver novos tratamentos para combater cepas fúngicas resistentes. A extensa seleção de antifúngicos apoia os avanços contínuos na pesquisa sobre fungos e no desenvolvimento de terapias antifúngicas eficazes.
Foram encontrados 939 produtos de "Antifúngicos"
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Posaconazole - Bio-X ™
CAS:Posaconazole is a triazole antifungal agent that inhibits the 14-alpha demethylase enzyme. This drug prevents the formation of fungal cell walls thus leading to fungal cell lysis. Posaconazole is shown to inflict its inhibitory activity against common pathogenic fungus such as Candida and Aspergillus species in severely immunocompromised patients.Fórmula:C37H42F2N8O4Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:700.78 g/molIsavuconazole
CAS:Anti-fungal; lanosterol 14α-demethylase inhibitorFórmula:C22H17F2N5OSPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:437.47 g/molCiclopirox
CAS:Pan-histone demethylase inhibitor; anti-fungal; iron-chelatorFórmula:C12H17NO2Cor e Forma:White PowderPeso molecular:207.27 g/molCaspofungin acetate
CAS:Produto ControladoInhibitor of glucan synthase; antifungal compoundFórmula:C52H88N10O15·2C2H4O2Pureza:Min. 90 Area-%Cor e Forma:PowderPeso molecular:1,213.42 g/molButoconazole nitrate
CAS:Butoconazole nitrate is an antifungal agent and is used for the treatment of vaginal yeast infections. It inhibits the synthesis of ergosterol, disrupting the fungal cell membrane.Fórmula:C19H18Cl3N3O3SPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:474.79 g/molTerbinafine hydrochloride
CAS:Activator of the two-pore domain potassium channel TASK3Fórmula:C21H26ClNPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:327.89 g/mol2-Methyl-4-isothiazolin-3-one HCl
CAS:Produto Controlado2-Methyl-4-isothiazolin-3-one HCl , also known as MIT hydrochloride is often used as a preservative in personal care products and other industrial applications. The product has shown to act as an antimicrobial and antifungal agent.Fórmula:C4H5NOS·HClPureza:Min. 95%Cor e Forma:White Slightly Yellow PowderPeso molecular:151.62 g/molIpconazole
CAS:Ipconazole is a fungicide with a mode of action that inhibits ergosterol biosynthesis, disrupting fungal cell membranes. It is used for seed treatment to protect crops like cereals and vegetables from fungal diseases. It's sold as a mixture of two isomers.Fórmula:C18H24ClN3OPureza:Min. 95%Peso molecular:333.86 g/molPosaconazole - Form I
CAS:Posaconazole is an antifungal agent that inhibits the 14-alpha demethylase enzyme which is responsible for the synthesis of the fungal cell wall component, ergosterol. This demethylase enzyme synthesizes ergosterol through converting lanosterol to ergosterol. Therefore Posaconazole prevents the formation of fungal cell walls with the appropriate membrane permeability thus leading to fungal cell lysis. Posaconazole can be used as an antifungal drug to treat opportunistic fungal infections in immunocompromised individuals such as HIV patients. Moreover it is shown to inflict its inhibitory activity against common pathogenic fungus such as Candida and Aspergillus species but also Mucorales and some Fusarium species, which are less common.Fórmula:C37H42F2N8O4Pureza:Min. 95%Peso molecular:700.78 g/molEfinaconazole
CAS:Efinaconazole is a triazole antifungal agent with action on fungal 14α-demethylase to inhibit ergosterol synthesis and is used for treating onychomycosis (fungal nail infections).Fórmula:C18H22F2N4OPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:348.39 g/molFR 901379 sodium
CAS:Impurity of Micafungin; anti-fungal
Fórmula:C51H81N8O21S·NaPureza:Min. 95%Cor e Forma:PowderPeso molecular:1,197.29 g/molAtovaquone - Bio-X ™
CAS:Atovaquone is an antimicrobial drug that is used for the treatment of Pneumocystis jirovecii pneumonia. This drug is an analog of ubiquinone and has good in vitro activity against Toxoplasma gondii.
Fórmula:C22H19ClO3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:366.84 g/molFilipin
CAS:Filipin is a polyene macrolide antifungal agent with action on cholesterol in cell membranes and is used for histochemical staining and research on cholesterol metabolism.Pureza:Min. 97 Area-%Cor e Forma:Yellow PowderVoriconazole - Bio-X ™
CAS:Voriconazole is a synthetic, lipophilic molecule that is used in the treatment of fungal infections. Voriconazole binds to ergosterol which is the major sterol in the cell wall of fungi and inhibits its synthesis, leading to cell death. This drug binds to the enzyme 14α-demethylase allowing the conversion of lanosterol into ergosterol. As a result, this binding leads to the inhibition of ergosterol synthesis, as well as other sterols that are necessary for fungal growth (e.g., squalene).
Fórmula:C16H14F3N5OPureza:Min. 95%Cor e Forma:PowderPeso molecular:349.31 g/molClotrimazole
CAS:Clotrimazole is an azole antifungal medication with action on fungal cell membrane disruption and is used for treating fungal infections like athlete's foot, ringworm, and vaginal yeast infections.
Fórmula:C22H17ClN2Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:344.84 g/molBifonazole - Bio-X ™
CAS:Bifonazole is an antifungal drug that is used for the treatment of fungal infections. This drug inhibits the production of ergosterol and destabilizes the fungal cytochrome p450 51 enzyme.Fórmula:C22H18N2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:310.39 g/molCiclopirox olamine - Bio-X ™
CAS:Ciclopirox is a broad-spectrum antifungal agent that is used to treat onychomycosis of fingernails and toenails in immunocomprised patients. Ciclopirox has been shown to work by binding to polyvalent metal cations such Al3+ and Fe3+. These cations interfere with cellular processes including mitochondrial electron transport and energy synthesis by inhibiting numerous enzymes, including cytochromes. Additionally, the plasma membrane of fungi appears to be altered by ciclopirox as well, leading to the disorder of internal structures.
Fórmula:C12H17NO2•C2H7NOPureza:Min. 95%Cor e Forma:PowderPeso molecular:268.35 g/molFluconazole - Bio-X ™
CAS:Fluconazole is an antifungal drug used to treat a wide range of fungal infections. Fluconazole is a cytochrome demethylase system inhibitor that acts by interfering with β-glucan biosynthesis. It has been shown to be effective in treating candidemia, a life-threatening form of candidiasis caused by the fungus Candida albicans. Fluconazole seems to be more effective than amphotericin B in treating some isolates of C. albicans, making it a valuable tool in the fight against this deadly fungal infection, although due to the increase of antimicrobial resistance, fluconazole has been studied in combination with other drugs (e.g. farnesol).Fórmula:C13H12F2N6OPureza:(%) Min. 95%Cor e Forma:PowderPeso molecular:306.27 g/molKetoconazole
CAS:Ketoconazole is an azole antifungal compound with a mode of action that inhibits ergosterol synthesis, disrupting fungal cell membranes. It is used for treating fungal infections of the skin and scalp.Fórmula:C26H28Cl2N4O4Cor e Forma:White PowderPeso molecular:531.43 g/molAlbendazole
CAS:Anthelmintic; inhibitor of tubulin polymerization
Fórmula:C12H15N3O2SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:265.33 g/mol
