Antifúngicos
Os antifúngicos são compostos especificamente projetados para interromper, prevenir e eliminar o crescimento de fungos. Nesta categoria, você encontrará uma ampla variedade de agentes antifúngicos essenciais para pesquisa e aplicações terapêuticas. Esses compostos são cruciais no tratamento de infecções fúngicas e na prevenção de sua recorrência, tornando-os ferramentas vitais tanto em ambientes médicos quanto agrícolas. Pesquisadores e profissionais de saúde podem explorar inúmeros antifúngicos para entender seus mecanismos, otimizar sua eficácia e desenvolver novos tratamentos para combater cepas fúngicas resistentes. A extensa seleção de antifúngicos apoia os avanços contínuos na pesquisa sobre fungos e no desenvolvimento de terapias antifúngicas eficazes.
Foram encontrados 835 produtos de "Antifúngicos"
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Diamthazole
CAS:<p>Diamthazole (Dimazole) is an antifungal agent that can be used in the infection research[1].</p>Fórmula:C15H23N3OSCor e Forma:SolidPeso molecular:293.43Diethofencarb
CAS:<p>Diethofencarb: a fungicide effective against Botrytis cinerea and resistant Botryis strains.</p>Fórmula:C14H21NO4Cor e Forma:SolidPeso molecular:267.32BI-10
CAS:<p>BI-10, paired with fluconazole, hinders fungal growth, increases ROS, decreases MMP, and changes membrane permeability.</p>Fórmula:C23H17BrN2OCor e Forma:SolidPeso molecular:417.3Antifungal agent 2
CAS:<p>Antifungal agent 2 suppresses growth of Cryptococcus, Candida, Aspergillus at ≥0.5 μg/mL.</p>Fórmula:C19H11Br2F3N4O2Pureza:98%Cor e Forma:SolidPeso molecular:544.12FBA-IN-1
CAS:<p>FBA-IN-1 (2a11) is the first covalent, allosteric CaFBA inhibitor, effective against Azole-resistant strains with a MIC 80 of 1 μg/mL.</p>Fórmula:C15H13NOSePureza:98.79%Cor e Forma:SolidPeso molecular:302.23Lipoxamycin
CAS:<p>Lipoxamycin is an inhibitor of serine palmitoyl-transferase.</p>Fórmula:C19H36N2O5Pureza:98%Cor e Forma:SolidPeso molecular:372.541F5
CAS:<p>41F5: Anti-fungal with MIC50 0.4-0.8 μM and IC50 0.87 μM against Histoplasma; 62x more selective for yeast vs host cells.</p>Fórmula:C21H22N2OSCor e Forma:SolidPeso molecular:350.48Flutolanil
CAS:<p>Flutolanil: a fungicide targeting R. solani in rice, toxic to zebrafish.</p>Fórmula:C17H16F3NO2Cor e Forma:SolidPeso molecular:323.31Debneyol
CAS:<p>Debneyol exhibits more potent fungicidal activity than validamycin.</p>Fórmula:C15H26O2Cor e Forma:SolidPeso molecular:238.371-(6-Amino-3,5-difluoro-2-pyridinyl)-7-[3-[3-[[1-(6-amino-3,5-difluoro-2-pyridinyl)-3-carboxy-8-chloro-6-fluoro-1,4-dihydro-4-oxo-7- quinolinyl]amino]-2-hydroxypropoxy]-1-azetidinyl]-8-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
CAS:<p>1-(6-Amino-3,5-difluoro-2-pyridinyl)-7-[3-[3-[[1-(6-amino-3,5-difluoro-2-pyridinyl)-3-carboxy-8-chloro-6-fluoro-1,4-dihydro-4-oxo-7-quinolinyl]amino]-2-hydroxypropoxy]-1-azetidinyl]-8-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid is a fluoroquinolone antibiotic, engineered through synthetic chemistry. It is derived from chemical sources involving complex organic synthesis, highlighting its intricate molecular architecture. Its mode of action is distinctive, as it inhibits bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication and transcription. This interference with bacterial DNA processes results in bactericidal effects, effectively eliminating susceptible bacterial strains.</p>Fórmula:C36H24Cl2F6N8O8Pureza:Min. 95%Peso molecular:881.52 g/molRilopirox
CAS:<p>Rilopirox is a synthetic fungicidal antimycotic with hydrophobic characteristics.</p>Fórmula:C19H16ClNO4Pureza:99.17% - 99.72%Cor e Forma:SolidPeso molecular:357.79Pramiconazole
CAS:<p>Pramiconazole (R126638), an oral antifungal, treats dermatophyte and yeast infections in seborrheic dermatitis.</p>Fórmula:C35H39F2N7O4Pureza:98.59% - 99.41%Cor e Forma:SolidPeso molecular:659.73Flutrimazole
CAS:<p>Flutrimazole: a dual-action imidazole with anti-inflammatory and antifungal effects; ideal for topical use due to limited skin penetration.</p>Fórmula:C22H16F2N2Pureza:98.56%Cor e Forma:SolidPeso molecular:346.37ME1111
CAS:<p>ME1111, a succinate dehydrogenase inhibitor of Trichophyton species, serves as an antifungal agent effective against dermatophytes.</p>Fórmula:C12H14N2OPureza:99.45%Cor e Forma:SolidPeso molecular:202.25Micafungin FR-179642 impurity (acid)
CAS:<p>Micafungin is an antifungal drug that inhibits the synthesis of ergosterol, a vital component of fungal cell membranes. It is a cyclic peptide with a lipophilic fatty acid chain that has been modified to allow penetration into cells. Micafungin is active against Candida and Aspergillus species and has shown activity against some strains of Cryptococcus neoformans. The MIC (minimum inhibitory concentration) for this drug ranges from 0.06 to 1 microgram/mL, depending on the bacterial strain being tested. Micafungin FR-179642 impurity (acid) is an impurity in micafungin that can be present as trace amounts in the final product and may contribute to hemolytic activity. This impurity is formed by hydrolysis during the synthesis process.</p>Fórmula:C35H52N8O20SPureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:936.9 g/molPC945
CAS:<p>PC945 (Opelconazole) is an antifungal compound that inhibits CYP51A/CYP51B and can be used to study fungal infections of the lungs.</p>Fórmula:C38H37F3N6O3Pureza:98.89% - 99.37%Cor e Forma:SolidPeso molecular:682.73Dihydropenicillin F potassium
CAS:<p>Dihydropenicillin F potassium is a novel antibiotic compound, which is semisynthetic in nature, derived from the penicillin family. It is sourced through the modification of natural penicillins, bringing about enhanced stability and efficacy against certain resistant bacterial strains. The mode of action involves the inhibition of bacterial cell wall synthesis, primarily targeting the penicillin-binding proteins (PBPs). This disruption consequently leads to cell lysis and the eventual bacterial death.</p>Fórmula:C14H22N2O4S•KPureza:Min. 95%Peso molecular:353.5 g/molN,O-Diacetyltyramine
CAS:<p>N,O-Diacetyltyramine, isolated from the actinomycete Pseudonocardia endophytica VUK-10, exhibits both antibacterial activity against Gram-positive and Gram-negative bacteria, alongside fungi, and demonstrates cytotoxicity towards MDA-MB-231, HeLa, MCF-7, and OAW-42 cells [1].</p>Fórmula:C12H15NO3Cor e Forma:SolidPeso molecular:221.25Antifungal agent 24
CAS:<p>Antifungal agent 24 (Compound 6) is an antifungal agent that inhibits Candida albicans (MIC: 0.03 μg/ml).</p>Fórmula:C24H18F2N4OCor e Forma:SolidPeso molecular:416.42FR194738 free base
CAS:<p>FR194738 free base inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM. </p>Fórmula:C27H37NO2SPureza:99.13%Cor e Forma:SolidPeso molecular:439.65
