Antifúngicos
Os antifúngicos são compostos especificamente projetados para interromper, prevenir e eliminar o crescimento de fungos. Nesta categoria, você encontrará uma ampla variedade de agentes antifúngicos essenciais para pesquisa e aplicações terapêuticas. Esses compostos são cruciais no tratamento de infecções fúngicas e na prevenção de sua recorrência, tornando-os ferramentas vitais tanto em ambientes médicos quanto agrícolas. Pesquisadores e profissionais de saúde podem explorar inúmeros antifúngicos para entender seus mecanismos, otimizar sua eficácia e desenvolver novos tratamentos para combater cepas fúngicas resistentes. A extensa seleção de antifúngicos apoia os avanços contínuos na pesquisa sobre fungos e no desenvolvimento de terapias antifúngicas eficazes.
Foram encontrados 835 produtos de "Antifúngicos"
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HDAC-IN-87
CAS:<p>HDAC-IN-87 (Compound XII6) is a non-selective HDAC inhibitor with pIC50 values of 6.9 for HDAC4 and 5.8 for HDAC6. It exhibits fungicidal activity against P. sorghi and P. pachyrhizi. The acute oral LD50 in both male and female rats is greater than 500 mg/kg.</p>Fórmula:C13H7F5N4O2SCor e Forma:SolidPeso molecular:378.277Chitin synthase inhibitor 9
<p>CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.</p>Fórmula:C24H25N3O6Cor e Forma:SolidPeso molecular:451.47Antifungal agent 28
<p>Antifungal 28 disrupts Candida, hits fluconazole-resistant strains, and inhibits biofilms.</p>Fórmula:C22H29N5OSCor e Forma:SolidPeso molecular:411.56AnCDA-IN-1
CAS:<p>AnCDA-IN-1 (Compound J075-4187) is an inhibitor of chitin deacetylase (CDA) exhibiting antifungal properties. It possesses an IC50 of 4.24 μM against A. nidulans AnCDA. The compound demonstrates a minimum inhibitory concentration (MIC) of 260 μg/mL and a minimum fungicidal concentration (MFC) of 520 μg/mL for food spoilage fungi and plant pathogenic fungi. AnCDA-IN-1 is applicable for research in the antifungal domain.</p>Fórmula:C16H13ClN4O2Cor e Forma:SolidPeso molecular:328.753Antifungal agent 17
<p>Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).</p>Fórmula:C18H16Br2O2Cor e Forma:SolidPeso molecular:424.13Antifungal agent 100
CAS:<p>Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].</p>Fórmula:C23H21N3O4SCor e Forma:SolidPeso molecular:435.5Antibacterial agent 188
CAS:<p>Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].</p>Fórmula:C12H10N4SCor e Forma:SolidPeso molecular:242.3HSP90-IN-9
<p>HSP90-IN-9: potent HSP90 inhibitor, dose-dependent fungicide, impedes biofilm/morphology with FLC, reverses FLC resistance.</p>Cor e Forma:SolidIsopyrazam
CAS:<p>Isopyrazam, a plant protection product, exhibits potent antifungal activity. When applied to crops, it effectively inhibits the growth of various plant pathogenic fungi, significantly enhancing both the yield and quality of the crops. This compound demonstrates exceptional disease resistance capabilities in agricultural applications.</p>Fórmula:C20H23F2N3OCor e Forma:SolidPeso molecular:359.41Antifungal agent 127
CAS:<p>Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.</p>Fórmula:C13H12ClN3OCor e Forma:SolidPeso molecular:261.707Antifungal agent 125
CAS:<p>Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.</p>Fórmula:C13H10BrNO4SCor e Forma:SolidPeso molecular:356.192Hyalodendrin
CAS:<p>Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.</p>Fórmula:C14H16N2O3S2Cor e Forma:SolidPeso molecular:324.42WQ3810 TFA
<p>WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity of</p>Fórmula:C24H23F6N5O5Pureza:99.52%Cor e Forma:SoildPeso molecular:575.46CDA-IN-3
CAS:<p>CDA-IN-3 (NCDI) is a chitin deacetylase (CDA) inhibitor with antiparasitic properties. It disrupts chitin metabolism in nematodes, increasing ROS levels within these organisms and causing cellular damage. CDA-IN-3 significantly inhibits all developmental stages of Caenorhabditis elegans and can be utilized in research focused on anti-infective applications.</p>Fórmula:C16H27N3O3S2Cor e Forma:SolidPeso molecular:373.534CDA-IN-2
CAS:<p>CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.</p>Fórmula:C17H16N2O7Cor e Forma:SolidPeso molecular:360.318CDA-IN-1
CAS:<p>CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal activity. By inhibiting fungal CDA activity, it activates plant immune responses and leads to the accumulation of reactive oxygen species (ROS), hindering fungal growth. At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% on P. xanthii's PxCDA1 and 74.5% on PxCDA2. CDA-IN-1 is applicable in research on fungal plant diseases, such as cucumber powdery mildew and tomato gray mold.</p>Fórmula:C15H14N2O6Cor e Forma:SolidPeso molecular:318.281Chitin synthase inhibitor 8
<p>Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infections</p>Fórmula:C23H23N3O5Cor e Forma:SolidPeso molecular:421.45Furametpyr
CAS:<p>Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.</p>Fórmula:C17H20ClN3O2Pureza:98%Cor e Forma:SolidPeso molecular:333.81Antifungal agent 12
<p>Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.</p>Fórmula:C20H16F3N7O2S2Cor e Forma:SolidPeso molecular:507.51Antifungal agent 11
<p>Antifungal agent 11 has a good antifungal effect.</p>Fórmula:C21H19F2N7O3S2Cor e Forma:SolidPeso molecular:519.55
