Antimicrobianos

Applications Used in the synthesis of some novel thiazolidine-2,4-dione derivatives having antimicrobial activity.
References Colca, J., et al.: J. Biol. Chem., 278, 21972 (2003), Galimand, M., et al.: Antimicrob. Agents Chemother., 47, 2565 (2003), Rostom, S., et al.: Bioorg. Med. Chem., 17, 882 (2009),

Applications Indolicidin is an antimicrobial peptide containing multiple tryptophan residues.

Applications 3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER (cas# 793-19-1) is a useful research chemical.

Applications 4-​Methyl-​benzenesulfonic Acid (2E)​-​[(5R)​-​2-​Methyl-​5-​(1-​methylethenyl)​-​2-​cyclohexen-​1-​ylidene]​hydrazide-d4 is an intermediate in synthesizing (+)-Limonene-d5 (L461742). It is present in blood oranges which show inhibition of angiogenesis in human colon cancer cells. Extracted from the oils of Mentha spicata it shows antimicrobial activity.
References Chidambara Murthy, K. et al.: Life Sci.,91, 429 (2012); Aggarwal, K. et al.: Flav. Frag. J., 17, 59 (2002)

Stability Hygroscopic
Applications 1,3-Dibenzyl-1H-benzo[d]imidazol-3-ium Chloride is a useful reagent in the preparation of the antimicrobial benzimidazolium compounds via N-alkylation of benzimidazoles with benzyl chloride.
References Meng, J. P., et al.: Adv. Mat. Res., 554, 1686 (2012)

Applications K252a is a protein kinase inhibitor. It is an analogue of staurosporine (S685000). It shows potent antitumor activity but no antimicrobial activity in vitro, or in vivo toxicity in rodents.
References Kase, H., et al.: J. Antibiot., 39, 1059 (1986); Yasuzawa, T., et al.; J. Antibiot., 39, 1072 (1986)

Applications 1H-Indazol-3-amine is a reagent used in the preparation of indazole derivatives as potential antimicrobial and antitumor agents.
References Plescia, S., et al.: ARKIVOC, 10, 163 (2010)

Applications (+)-Ledene is an essential oil that is synthesized by viridiflorene synthase. It has been studied as an antioxidant, antimicrobial, antibiofilm and to treat various cancers.
References Negreiros, M.O., et al.: Pharm. Biol, 54, 3272-3279 (2016)

Applications 1-Pyridin-2-yl-propan-2-one is an antimicrobial bioactive compound extracted from Lactarius vellereus fermenting liquor.
References Ji, H., et al.: Beijing Linye Daxue Xuebao, 30, 92 (2008); Song, R., et al.: From Faming Zhuanli Shenqing (2008), CN 101230368 A 20080730;

Applications CSA (cationic steroid antibiotics) is a class of facial amphiphiles with same mechanism of antimicrobial action as that of CPAs (cationic peptide antibiotics).
References Sundriyal, S., et al.: J. Mol. Model, 14, 265 (2008).

Stability Air Sensitive
Applications 4-(Phenylthio)-1,2-benzenediamine is used in the synthesis of bis(2-chloroethyl)aminophosphoryl-containing compounds which are potential anticancer agents. It is also used in the synthesis of 2-substituted-2,3-dihyrdro-5-thiophenoxy-1H-1,3,2-benzodiazaphosphole 2-oxides which exhibit antimicrobial activity.
References Rao, L. N., et al.: Phosphorus Sulfur, 177, 399 (2002); Rao, L. N., et al.: Phosphorus Sulfur, 158, 39 (2000)

Stability Hygroscopic
Applications Gentianose is a trisaccharide and phytochemical found in bitter gentian teas with antimicrobial, anti-inflammatory and antioxidant properties.
References Olennikov, D. N.; et al.: Molecules, 20, 20014 (2015).