Antiparasitários
Os antiparasitários são compostos projetados para tratar e prevenir infecções parasitárias, inibindo o crescimento e a sobrevivência dos parasitas. Esta categoria inclui uma variedade de agentes antiparasitários destinados exclusivamente ao uso em laboratório e não para consumo humano. Estes produtos são essenciais para fins de pesquisa, permitindo que cientistas estudem os ciclos de vida dos parasitas, mecanismos de ação e o desenvolvimento de resistência. O uso de antiparasitários em ambientes laboratoriais auxilia na descoberta e otimização de novos tratamentos para doenças parasitárias, contribuindo para os avanços na parasitologia médica e veterinária. Pesquisadores dependem desses produtos para aprimorar sua compreensão sobre infecções parasitárias e desenvolver terapias mais eficazes.
Foram encontrados 704 produtos de "Antiparasitários"
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Monodesethyl Quinacrine, Dihydrochloride
CAS:Produto ControladoFórmula:C21H26ClN3O·2ClHCor e Forma:NeatPeso molecular:444.83(2R,3R)-Benzhydryl 2,3-bis(benzyloxy)-4-hydroxybutanoate
Produto Controlado<p>Applications (2R,3R)-Benzhydryl 2,3-bis(benzyloxy)-4-hydroxybutanoate is an intermediate in synthesizing 4-Phospho D-Erythronate (P355000), which is an intermediate in the synthesis of pyridoxal 5'-phosphate in some bacteria and an inhibitor of ribose 5-phosphate isomerase. Phosphorylated aldonic acids are strong inhibitors of 6-phosphogluconate dehydrogenase, and 4-phospho-D-erythronate (4PE) and 4-phospho-D-erythronohydroxamate are two of the strongest inhibitors of the Trypanosoma brucei enzyme.<br>References Tanaka, N., et al.: J. Mol. Biol., 324, 519 (2002); Fitzpatrick, T., et al.: Biochem. J., 407, 1 (2007); Kalliri, E., et al.: J. Bacteriol., 190, 3793 (2008)<br></p>Fórmula:C31H30O5Cor e Forma:NeatPeso molecular:482.5671-Undecyne
CAS:Produto Controlado<p>Applications 1-Undecyne is a reagent used in organic chemical synthesis. Used in the synthesis of antimalarial and antitrypanosomal agents.<br>References Wube, A. et al.: Molecule, 19, 14204 (2014); Sun, S. et al.: Chin. Chem. Polym. Sci., 33, 184 (2015);<br></p>Fórmula:C11H20Cor e Forma:NeatPeso molecular:152.28Artemisic Acid
CAS:<p>Applications Artemisic Acid is a derivative of Artemisinin (A777500), an antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial.<br>References Klayman, D.L., et al.: Science, 228, 1049 (1985), Price, R.N., et al.: Expert Opin. Invest. Drugs, 9, 1815 (2000), Meshnick, S.R., et al.: Int. J., Parasitol., 32, 1655 (2002),<br></p>Fórmula:C15H22O2Cor e Forma:NeatPeso molecular:234.33(R)-2-Methyl-1-tosylaziridine
CAS:Produto Controlado<p>Applications (R)-2-Methyl-1-tosylaziridine can be used to synthesize tetrahydropyridines, morpholines, chiral β-and γ-amino ethers, and (ent)-korupensamine D. Korupensamine D is a natural product that exhibits antimalarial properties.<br>References Ghorai, M. K., et al.: J. Org. Chem. 77, 3740 (2012); Pattenden, L. C., et al.: Org. Lett. 8, 3089 (2006); Hallock, Y. F., et al.: J. Nat. Prod. 60, 677 (1997)<br></p>Fórmula:C10H13NO2SCor e Forma:NeatPeso molecular:211.281-[4-(1H-Indol-3-Yl)Piperidino]Ethan-1-One
CAS:Produto Controlado<p>Applications 1-[4-(1h-Indol-3-Yl)Piperidino]Ethan-1-One (cas# 30030-83-2) is a useful research chemical.<br></p>Fórmula:C15H18N2OCor e Forma:NeatPeso molecular:242.31α-Hydroxy-3-phenoxybenzeneacetonitrile (>90%)
CAS:Produto ControladoFórmula:C14H11NO2Pureza:>90%Cor e Forma:NeatPeso molecular:225.242-Acetamido-2-deoxy-4-O-(β-D-galactofuranosyl)-α,β-D-glucopyranose
CAS:Produto Controlado<p>Applications Synthetic galactofuranose-containing oligosaccharides could be useful for the identification of strains of T. cruzi as well as for studies on the inhibition of the biosynthesis of these unique O-linked chains.<br>References Gallo-Rodriguez, C., et al.: J. Org. Chem., 61, 1886 (1996)<br></p>Fórmula:C14H25NO11Cor e Forma:NeatPeso molecular:383.348N-Decylaminoethanol
CAS:Produto Controlado<p>Applications Used in the antileishmanial activity of lipidic amino alcohols.<br>References Coimbra, E.: Chem. Biol. Drug Des. 75, 233 (2010).<br></p>Fórmula:C12H27NOCor e Forma:NeatPeso molecular:201.357-Amino-1,5-dihydro-5-imino-2,8-quinolinedione Hydrochloride
CAS:Produto Controlado<p>Applications 7-Amino-1,5-dihydro-5-imino-2,8-quinolinedione is a quinoline derivative. The principle use of Quinoline is the preparation of 8-hydroxyquinoline (H953265), a versatile chelating agent and precursor to certain antimalarial and anticancer drugs.<br>References Pettit, G.R., et al.: J. Org. Chem., 33, 1089 (1968);<br></p>Fórmula:C9H8ClN3O2Cor e Forma:NeatPeso molecular:225.633,6-Bis(3,5-dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetrazine
CAS:Produto ControladoFórmula:C28H38O19Cor e Forma:NeatPeso molecular:678.59p-Cyanoacetophenone
CAS:Produto Controlado<p>Applications Used in the preparation of antimalarial isonitriles.<br>References Singh, C. et al.; Bioorgan. Med. Chem. Lett. 12, 2277 (2002)<br></p>Fórmula:C9H7NOCor e Forma:NeatPeso molecular:145.16Pseurotin A
CAS:Produto Controlado<p>Applications Pseurotin A shows antiparasitic and anticancer activity. It exhibits inhibition towards IgE (immunoglobin E) production.<br>References Martinez-Luis, S. et al.: Nat. Prod. Comm., 7, 165 (2012); Bioorg. Med. Chem. Lett., 19, 1457 (2009);<br></p>Fórmula:C22H25NO8Cor e Forma:NeatPeso molecular:431.444-Methoxy-6-(2-phenylethyl)-2H-pyran-2-one
CAS:Produto Controlado<p>Applications 4-Methoxy-6-(2-phenylethyl)-2H-pyran-2-one is a Kawain (K145490) derivative that is known to exhibit antimalarial and antituberculosis activities. 4-Methoxy-6-(2-phenylethyl)-2H-pyran-2-one has been identified as a lead compound for the dual treatment of malaria and leishmaniasis.<br>References McCracken, S.T., et al.: Bioorg. Med. Chem., 20, 1482 (2012); Elzaawely, A.A.. et al.: Food. Chem., 103, 486 (2007); Xuan, T.D., et al.: J. Natural. Med., 62, 188 (2008);<br></p>Fórmula:C14H14O3Cor e Forma:NeatPeso molecular:230.26α-(3,4-Diethoxyphenyl)-6,7-diethoxy-1-isoquinolinemethanol
CAS:Produto Controlado<p>Applications α-(3,4-Diethoxyphenyl)-6,7-diethoxy-1-isoquinolinemethanol is an intermediate in synthesizing Ethaverine (E676700), which is an analogue of Papaverine (P190500), an antispasmodic. An isoquinoline derivative with the potential for antimicrobial, antimalarial and cytotoxic antiviral agents.<br>References Kaplan, D., et al.: Biochem. J., 201, 605 (1982), Hifnawy, M.S., et al.: Anal. Profiles Drug Subs., 17, 367 (1988); Iwasa, K. et al.: Bioorg. Med. Chem., 9, 2871 (2001);<br></p>Fórmula:C24H29NO5Cor e Forma:NeatPeso molecular:411.491,2-Diamino-2-methyl Propane
CAS:Produto Controlado<p>Applications 1,2-Diamino-2-methyl Propane is a reactant used in the preparation of neocryptolepine analogs with antimalarial activity.<br>References Shaban, E., et. al.: Heterocycles, 89, 1055 (2014)<br></p>Fórmula:C4H12N2Cor e Forma:NeatPeso molecular:88.15Ethaverine
CAS:<p>Applications Ethaverine is an analogue of Papaverine (P190500), an antispasmodic. An isoquinoline derivative with the potential for antimicrobial, antimalarial and cytotoxic antiviral agents.<br>References Kaplan, D., et al.: Biochem. J., 201, 605 (1982), Hifnawy, M.S., et al.: Anal. Profiles Drug Subs., 17, 367 (1988); Iwasa, K. et al.: Bioorg. Med. Chem., 9, 2871 (2001);<br></p>Fórmula:C24H29NO4Cor e Forma:NeatPeso molecular:395.495-Nitro-1H-quinolin-2-one
CAS:Produto Controlado<p>Applications 5-Nitro-1H-quinolin-2-one is used in the synthetic preparation of novel antileishmanial agents for Leishmania donovani promastigotes.<br>References Paloque, L., et al.: Europ. J. Med. Chem., 54, 75 (2012);<br></p>Fórmula:C9H6N2O3Cor e Forma:NeatPeso molecular:190.163-Chloro-N-(3-methoxyphenyl)propanamide
CAS:Produto Controlado<p>Applications 3-Chloro-N-(3-methoxyphenyl)propanamide acts as an inhibitor towards DOXP-reductoisomerase (DXR), a primary target for antimalarial drugs.<br>References Bodill, T. et al.: Bioorg. Med. Chem., 21, 4332 (2013);<br></p>Fórmula:C10H12ClNO2Cor e Forma:NeatPeso molecular:213.66
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