Flavonóides

<p>(E)-Deschlorophenyl fluoxastrobin is a synthetic fungicide, which is derived from the strobilurin class of compounds, originally sourced from natural fungal metabolites. It functions by inhibiting mitochondrial respiration in fungal cells through disruption of the cytochrome bc1 complex, specifically at the Qo site. This mode of action effectively curtails the energy supply of the pathogen, leading to its death, and is integral in managing resistance issues known to occur with other fungicide groups.</p>

<p>Enhances TRAIL-induced apoptosis in MOLT-4- cells</p>

<p>Maackiaflavanone is a specialized flavanone, which is a type of natural compound. It is derived from the Maackia plant species, particularly found in temperate regions and known for its rich phytochemical profile. The flavanone exhibits its activity primarily through its interaction with cellular pathways associated with oxidative stress and inflammation, modulating various biochemical signals that can influence cell behavior.</p>

<p>5,6,7,2'-Tetrahydroxyflavone is a naturally occurring flavonoid, which is commonly found in various plants. As a bioactive compound, it is typically derived from the leaves, stems, or fruits of these plants, where it plays a crucial role in plant defense. The mode of action of 5,6,7,2'-Tetrahydroxyflavone is primarily through its potent antioxidant activity. It scavenges free radicals and reduces oxidative stress, thereby contributing to cellular protection and stability.</p>

<p>Gardenin B is a microbial biocontrol agent that originates from Streptomyces bacteria. It functions as a secondary metabolite deriving from its microbial source. The mode of action involves inhibiting the growth of plant-pathogenic fungi by disrupting their cellular processes and interfering with spore germination or hyphal proliferation. Gardenin B is primarily utilized in agricultural settings to control fungal diseases in crops, reducing reliance on synthetic chemical fungicides. Its application is integrated into plant protection programs to enhance agricultural sustainability and improve crop yields while minimizing the environmental impact. Scientists are investigating its mechanisms and potential for broader applications.</p>

<p>Euchrestaflavanone A is a naturally occurring flavanone, which is a type of polyphenolic compound. It is sourced from plants, specifically derived from the roots of Euchresta formosana, a species used traditionally in herbal medicine. The mode of action of Euchrestaflavanone A involves its interaction with various molecular pathways, influencing antioxidant activity and modulating enzyme function. It exhibits bioactive properties, including anti-inflammatory, antioxidant, and potential anticancer effects.</p>

<p>6,7,4'-Trihydroxyflavanone is a naturally occurring flavonoid, which is found in various plant sources, particularly in citrus fruits and certain medicinal herbs. This compound is characterized by its presence of hydroxyl groups, enhancing its reactivity and interaction with biological systems. The mode of action of 6,7,4'-Trihydroxyflavanone primarily involves its antioxidant activity. It can scavenge free radicals and chelate metal ions, thereby reducing oxidative stress within cellular environments. This property is critical in maintaining cellular integrity and preventing damage caused by reactive oxygen species.</p>

Ombuin is a flavonoid compound, which is a naturally occurring substance found in a variety of plants. It functions primarily as an antioxidant by scavenging free radicals and inhibiting oxidative stress within biological systems. This mode of action is pivotal in mitigating cellular damage, thereby contributing to anti-inflammatory processes.

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2,3-Dihydrohinokiflavone is a natural bioflavonoid compound, which is typically derived from various plant sources, particularly those native to East Asia. This compound belongs to the broader flavonoid family, known for their antioxidant properties. Its mode of action involves modulating various signaling pathways, which can lead to anti-inflammatory and antioxidant effects. It achieves this by inhibiting the production of pro-inflammatory cytokines and scavenging free radicals, thus reducing oxidative stress in biological systems.

<p>(S)-4',7-Dimethyl equol is an isoflavandiol, which is a metabolite of the soy isoflavone daidzein. It is produced in the human gut by bacterial metabolism, provided the individual has the appropriate intestinal microbiota capable of this transformation. The compound exhibits estrogenic activity, primarily due to its structural similarity to the endogenous hormone 17β-estradiol, allowing it to bind to estrogen receptors.</p>

5,7-Dimethoxyflavanone is a flavonoid derivative, which is a type of polyphenolic compound predominantly found in plants. This compound is often isolated from various botanical sources, where it contributes to the plant's adaptive defense mechanisms against environmental stressors. The mode of action of 5,7-Dimethoxyflavanone involves interaction with cellular signaling pathways, potentially influencing antioxidant, anti-inflammatory, and enzyme inhibition activities through modulation of molecular targets.

7,4'-Dihydroxy-6,8-diprenylflavanone is a prenylated flavonoid, which is a type of naturally occurring compound found in various plants. This compound is often derived from specific plant species known for their rich flavonoid content. The prenylation of flavonoids, such as 7,4'-Dihydroxy-6,8-diprenylflavanone, often enhances their biological activity.

<p>Licoisoflavanone is a naturally occurring flavonoid compound, which is derived from the roots of plants such as Glycyrrhiza glabra, commonly known as licorice. This phytochemical is primarily obtained through extraction and isolation from licorice roots, where it is present as part of a complex mixture of bioactive compounds. The mode of action of licoisoflavanone involves its ability to interact with various biological pathways, including inhibitory effects on bacterial cell wall synthesis and disruption of microbial cellular functions, as well as scavenging free radicals to exert antioxidant effects.</p>

5-Methoxyflavanone is an organic compound, which is a flavonoid derivative obtained primarily through synthetic procedures involving the modification of flavanones. This compound is synthesized through specific chemical reactions that introduce a methoxy group into the flavanone structure, thereby altering its chemical and biological properties.

<p>6,2',4'-Trimethoxyflavone is a flavonoid compound, which is a type of phytochemical found in various plant species. It is derived from natural sources, including certain medicinal herbs and plants known for their bioactive properties. This specific flavone is characterized by its three methoxy groups attached at distinct positions on the flavonoid backbone, which confer unique chemical properties and biological activities.</p>

3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone, (2R,3S)- is a naturally occurring prenylated flavanone, which is primarily sourced from various plant species. This compound is part of the larger flavonoid family and is often found in certain medicinal plants known for their wide range of therapeutic properties. Its structure comprises a flavanone backbone, modified by hydroxyl, methoxy, and prenyl groups that contribute to its distinctive chemical profile.

<p>2'-Methoxybiochanin A is a naturally occurring isoflavone, which is predominantly derived from the plant Trifolium pratense, commonly known as red clover. This compound is characterized by its unique chemical structure that includes a methoxy group, which differentiates it from other isoflavones. The mode of action of 2'-Methoxybiochanin A involves its interaction with estrogen receptors, as well as its ability to modulate various biological pathways linked to inflammation and oxidative stress.</p>

<p>7-Benzyloxy-3',4'-dimethoxyisoflavone is a synthetic isoflavone derivative, which is a specialized compound designed for research and potential pharmacological applications. Isoflavones are naturally occurring compounds found predominantly in plants like soybeans and are studied for their biological activities. This particular compound is synthetically modified with methoxy groups, enhancing its stability and bioavailability.</p>

<p>Icarisid I is a sophisticated protease inhibitor, which is derived from a natural source. This compound exhibits a high affinity for specific proteases, making it an invaluable tool in research and biotechnological applications. The compound's mode of action involves the selective and competitive inhibition of protease enzymes, effectively blocking their activity within biological systems. This can be particularly useful in studies aiming to elucidate the role of proteases in various biochemical pathways and disease processes.</p>

Quercetin 3-(2''-galloyl-alpha-L-arabinopyranoside) is a flavonoid derivative, which is found predominantly in plants. It is derived from the modifications of quercetin, a widely studied polyphenolic compound endemic to many fruits, vegetables, and grains. The compound acts primarily as an antioxidant, engaging in scavenging free radicals and chelating metal ions, which contributes to reducing oxidative stress in biological systems.

<p>Quercetin 3-O-rutinoside-7-O-glucoside is a flavonoid derivative, which is a specialized plant metabolite known for its diverse bioactive properties. Extracted primarily from plant sources, this compound is a glycoside derivative of quercetin, a well-known flavonoid found abundantly in fruits and vegetables. The specific glycosylation at the 3-O-rutinoside and 7-O-glucoside positions enhances its solubility and bioavailability compared to its aglycone form.</p>

<p>Hydroxygenkwanin is a type of flavonoid, which is a natural compound extracted from various plant sources, particularly those within the Asteraceae family. It functions predominantly through its ability to modulate multiple signaling pathways, including antioxidant, anti-inflammatory, and apoptosis-inducing activities. Hydroxygenkwanin acts by influencing cellular signaling cascades, enhancing or inhibiting the expression of specific proteins and genes related to cell cycle regulation and immune response.</p>

<p>Bilobetin is a flavonoid compound, which is sourced from the leaves of the Ginkgo biloba tree. This compound primarily functions through its antioxidative properties, influencing a variety of neural pathways. Its mode of action involves the scavenging of reactive oxygen species and modulation of cellular signaling pathways that impact synaptic transmission and neuroplasticity.</p>

<p>Licoisoflavone A is a naturally occurring isoflavone, which is extracted from plants of the Glycyrrhiza genus, notably known for their medicinal applications. This compound exhibits a unique mode of action, primarily through its anti-inflammatory and antioxidant activities, which involve modulation of various signaling pathways and inhibition of pro-inflammatory cytokines. By influencing these pathways, Licoisoflavone A can mitigate oxidative stress and reduce inflammation, showcasing its potential in therapeutic applications.</p>

<p>Vincetoxicoside B is a natural compound, specifically a glycoside, which is derived from plant sources, notably within the genus Vincetoxicum. This compound, isolated from certain medicinal plants, represents a significant interest in phytochemistry due to its complex molecular structure and potential biological activities.</p>

<p>2',5,7-Trihydroxy-8-methoxyflavanone is a polyphenolic flavanone compound, which is a type of flavonoid. It is sourced primarily from plant materials, particularly those rich in flavonoid content, such as specific fruits, vegetables, and herbs. This compound exerts its effects primarily through its antioxidant properties, where it functions by scavenging free radicals and inhibiting oxidative stress within biological systems.</p>

<p>Warangalone is a type of flavonoid compound, which is derived from the roots of the medicinal plant Abrus precatorius. This compound is characterized by its polyphenolic structure, making it an excellent candidate for various biochemical interactions. Warangalone exhibits its mode of action primarily through the disruption of microbial cell walls, leading to effective antimicrobial activity. Its interactions with microbial membranes result in altered permeability, ultimately inhibiting the growth and replication of various bacterial and fungal species.</p>

Podocarpus flavanone is a naturally occurring flavonoid derivative, which is sourced from the Podocarpus genus, a group of coniferous trees native to the Southern Hemisphere. The compound is characterized by its polyphenolic structure, contributing to its ability to engage in a range of biochemical interactions. Its mode of action primarily involves the inhibition of microbial growth through disruption of microbial cell membranes and interference with key enzymatic pathways necessary for cell survival.

<p>Vaccarin is a bioactive flavonoid, which is derived from the plant Vaccaria segetalis. It is a naturally occurring compound, primarily sourced from the seeds of this plant. The mode of action of Vaccarin involves its ability to interact with various biological pathways, particularly those related to anti-inflammatory and antioxidant processes. It acts by modulating enzyme activity and gene expression associated with these pathways, potentially influencing cellular behavior and physiological responses.</p>

<p>Isomucronulatol is a naturally occurring flavonoid compound, which is a secondary metabolite sourced primarily from various plant species. It exhibits significant antioxidant activity by scavenging free radicals and reducing oxidative stress, which can damage cellular components such as lipids, proteins, and DNA. Additionally, Isomucronulatol demonstrates anti-inflammatory effects by modulating signaling pathways involved in the inflammatory response, thereby reducing the production of pro-inflammatory cytokines.</p>

<p>Sotetsuflavone is a flavonoid-based compound, which is a type of product derived from natural plant sources, specifically certain species in the Cycad family. It is characterized by its complex chemical structure, which enables it to interact with various biological systems. The mode of action of Sotetsuflavone involves modulation of signaling pathways and interaction with specific cellular receptors, which can influence enzymatic activity and gene expression. These interactions suggest its potential in influencing oxidative stress and inflammatory responses.</p>

<p>Scutellarein tetramethyl ether is a methylated flavonoid compound, which is a result of structural modifications to scutellarein, itself a naturally occurring flavone. This compound is derived from various plant sources, particularly those within the Scutellaria genus, known for their bioactive flavonoid content. The modification involves methylation of hydroxyl groups, which can augment its bioavailability and stability.</p>

<p>Prunetin-4'-glucoside is a specialized flavonoid compound, categorized as a glucoside, which is derived from natural plant sources. This glycosylated form of prunetin is found in various plants and serves as part of the plant's defense mechanism. Its mode of action involves antioxidative properties that neutralize free radicals, thus protecting cellular structures from oxidative damage. This mechanism is crucial as oxidative stress is implicated in numerous diseases.</p>

Plantanone B is a naturally-derived compound, which is an anti-inflammatory agent sourced from the Plantago species. It is known for its distinct bioactive properties attributed to its unique phytochemical structure. The compound primarily functions by modulating inflammatory pathways, specifically targeting the downregulation of pro-inflammatory cytokines and inhibiting the production of reactive oxygen species. This mode of action underscores its potential in addressing inflammation-associated cellular processes.

8-Prenylquercetin is a prenylated flavonoid, a compound that belongs to the larger class of polyphenols. It is typically derived from various plant sources, often synthesized from quercetin, which is abundant in fruits and vegetables. The addition of a prenyl group is believed to enhance its biological activity and lipophilicity compared to non-prenylated flavonoids.

2-Hydroxynaringenin is a flavonoid compound, which is derived from the extraction and purification of various citrus fruits, particularly from the peel and pulp. It belongs to a class of secondary metabolites found predominantly in these plants, functioning as part of their natural defense mechanism.

<p>R-Equol is a chiral compound classified as an isoflavandiol, which is a type of non-steroidal estrogen. It is derived from the metabolic conversion of daidzein, an isoflavone predominantly found in soy products, by intestinal microbiota in some individuals. The presence of equol-producing bacteria is necessary for this biotransformation process.</p>

<p>6-Chloroflavone is a synthetic flavonoid derivative, which is a modified chemical compound originating from naturally occurring flavonoids found in various plants. Structurally, it is characterized by the substitution of a chlorine atom at the 6th position on the flavone backbone. This chemical modification is designed to alter its physicochemical properties and enhance its biological activity.</p>

<p>Cudraflavanone B is a bioactive flavonoid, which is a type of polyphenolic compound. It is derived from natural sources, prominently found in the roots of Cudrania tricuspidata, a plant known for its traditional use in herbal medicine. The mode of action of Cudraflavanone B involves various biochemical pathways, including the modulation of enzyme activity and signaling pathways. It exhibits antioxidant, anti-inflammatory, and antimicrobial properties by interacting with cellular mechanisms that regulate oxidative stress and inflammatory responses.</p>

<p>Cirsimarin is a natural flavonoid compound, which is extracted from certain plant species, primarily in the Asteraceae family. It functions by modulating various biochemical pathways through its potent anti-inflammatory, antioxidant, and hepatoprotective activities. Cirsimarin exerts its effects by scavenging free radicals, inhibiting inflammatory mediators, and supporting liver function through upregulation of detoxifying enzymes.</p>

Pratensein 7-O-glucoside is a naturally occurring flavonoid glucoside, which is extracted from various plant sources such as red clover, Trifolium pratense. This compound is formed when the flavonoid pratensein is glycosylated at the 7th position with glucose. As a member of the isoflavone group, Pratensein 7-O-glucoside may exert its effects primarily through antioxidant mechanisms, neutralizing reactive oxygen species and reducing oxidative stress.

<p>Isomedicarpin is a flavonoid compound, which is naturally derived from plant sources. It is isolated predominantly from certain species within the Leguminosae family, where these compounds often play a role in the plant's defense mechanisms. The mode of action of isomedicarpin involves disrupting microbial cell membranes and interfering with essential biochemical pathways, which contributes to its antimicrobial efficacy.</p>

<p>Alpinumisoflavone-4'-methyl ether is a methoxyisoflavone, which is a type of naturally occurring phenolic compound. It is derived from specific plant sources, including certain species within the Fabaceae family, known for their rich isoflavonoid content. These compounds are synthesized in plants as part of their defense mechanisms against environmental stresses and pathogens.</p>

<p>5,7,2',4'-Tetrahydroxy-8,3'-di(gamma,gamma-dimethylallyl)-isoflavanone is a prenylated isoflavanone, which is a type of flavonoid compound extensively studied in natural product chemistry. It is primarily sourced from specific plant species known for their rich secondary metabolite profiles, often within the Fabaceae family. The mode of action of this compound involves its interaction at the molecular level with various biological targets, potentially leading to antioxidant, anti-inflammatory, or antimicrobial effects. These actions are mediated through the compound’s ability to modulate enzyme activities, interact with cellular membranes, and influence signaling pathways.</p>

<p>Iso-Osajin is a naturally occurring compound that falls under the category of prenylated flavonoids. It is isolated from the seeds of Psoralea corylifolia, a plant traditionally used in various medicinal systems. The compound exhibits its mode of action primarily through antimicrobial activities, potentially disrupting microbial cell membranes or inhibiting essential enzymes. Iso-Osajin has been of considerable interest due to its promising pharmacological effects, including antibacterial, antifungal, and possibly antiviral properties.</p>

<p>Scutellarin methylester is a flavonoid derivative, which is a modified form of the naturally occurring compound scutellarin. It originates from plant sources, notably from species within the *Scutellaria* genus. The modification to a methyl ester potentially increases its bioavailability and modifies its pharmacokinetic properties.</p>

<p>Daidzein bis-tert-butyldimethylsilyl ether is a synthetic derivative of the isoflavone daidzein, which is primarily sourced from soybeans and other legumes. It’s modified through the attachment of tert-butyldimethylsilyl ether groups, enhancing its stability and facilitating its use in various experimental conditions. This compound acts as a precursor or an intermediate in the synthesis of other complex molecules, allowing detailed structural or functional studies on isoflavones in biochemical pathways.</p>

<p>Europetin is a flavonoid, a type of naturally occurring compound, which is derived from various plant sources. The compound functions as an anti-inflammatory agent by modulating signaling pathways involved in inflammatory responses, such as the NF-kB pathway. Its efficacy in reducing inflammatory mediators makes it a subject of interest for exploring therapeutic interventions.</p>

<p>Amentoflavone-7,7'',4',4''-tetramethyl ether is a specialized bioflavonoid derivative, which is synthesized from the natural biflavonoid amentoflavone found in various plant sources, such as Ginkgo biloba and St. John's Wort. The structural modification involving methylation enhances its pharmacokinetic properties, such as bioavailability and metabolic stability, making it a subject of interest in the scientific community.</p>