Canabinóides
Os canabinoides são uma classe de compostos químicos diversos derivados de ácidos graxos ou poliquetídeos que atuam sobre os receptores canabinoides nas células, alterando a liberação de neurotransmissores no cérebro. Encontrados principalmente em plantas de cannabis, canabinoides como THC e CBD são amplamente estudados por seus efeitos terapêuticos, incluindo alívio da dor, propriedades anti-inflamatórias e uso potencial em doenças neurodegenerativas. Na CymitQuimica, você encontrará uma ampla variedade de canabinoides para pesquisa em farmacologia, neurobiologia e química medicinal.
Foram encontrados 371 produtos para "Canabinóides".
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Δ8-THC-C8
CAS:Δ8-THC-C8 is a semi-synthetic cannabinoid. It acts as an agonist for the cannabinoid receptor 1 (CB1) with an EC50 value of 13.8 nM.Fórmula:C24H36O2Cor e Forma:SolidPeso molecular:356.54CB2 receptor agonist 9
CAS:CB2 receptor agonist 9 (Compound 33) is an orally active agonist of cannabinoid receptor 2 (CB2 receptor) with an EC50 of 16.2 nM. It inhibits the expression of TNF-α, IL-1β, and IL-6, demonstrating anti-inflammatory activity in a DSS-induced acute colitis model in mice.Fórmula:C16H23N3O2SCor e Forma:SolidPeso molecular:321.44Drinabant
CAS:Drinabant (AVE-1625) is an orally active CB1 receptor antagonist.Fórmula:C23H20Cl2F2N2O2SPureza:99.8%Cor e Forma:SolidPeso molecular:497.38CB2 receptor agonist 2
CAS:CB2 receptor agonist 2 (ZINC72105556): potent, Ki=8.5 nM, high selectivity for CB2.Fórmula:C30H36N2O4Pureza:99.75%Cor e Forma:SolidPeso molecular:488.62Δ8-THC methyl ether
CAS:Δ8-THC methyl ether (compound 3) demonstrates a strong docking score of -10.167 kcal/mol for the CB2 receptor. Additionally, Δ8-THC methyl ether exhibits antinociceptive activity in mice.Fórmula:C22H32O2Cor e Forma:SolidPeso molecular:328.49CB2 PET Radioligand 1
CB2 PET Radioligand 1 (compound [18F]9) is a positron emission tomography (PET) radioligand with high affinity for the human cannabinoid receptor 2 (hCB2, Ki=7.Fórmula:C20H19F3N4OPureza:98%Cor e Forma:SolidPeso molecular:388.39SCOTfluor-89
CAS:SCOTfluor-89 is a small, conjugatable, orthogonal, and multicolor fluorescent group designed for in vivo imaging of cell metabolism.Fórmula:C12H14N4O7SeCor e Forma:SolidPeso molecular:405.22GFB-024
GFB-024 is a humanized antibody targeting CB1, which can be used to study obesity.Cor e Forma:LiquidPeso molecular:146.12 kDaCB2 receptor antagonist 2
Compound 39, also known as CB2 receptor antagonist 2, is a potent CB2 antagonist exhibiting an IC50 of 0.33 μM.Cor e Forma:Odour SolidHemopressin(human, mouse) TFA
CAS:Hemopressin TFA: nonapeptide from hemoglobin, oral CB1 inverse agonist, eases inflammatory pain.Fórmula:C52H80F3N13O14Pureza:98%Cor e Forma:SolidPeso molecular:1168.27UVI3502
UVI3502 is a cannabinoid receptor 1 (CB1) antagonist with an IC50 value of 4641 nM for CB1 and approximately 16200 nM for CB2. It can inhibit Gi/o protein coupling induced by the agonist CP55,940. UVI3502 shows potential for research into diseases related to the endocannabinoid system in the central nervous system, such as cognitive impairments and neurodegenerative disorders.CB2R/FAAH modulator-2
CAS:CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH.Fórmula:C24H33NO2Pureza:99.15%Cor e Forma:SolidPeso molecular:367.52Hemopressin(rat)
CAS:Peptide inhibitor for ep24.15, neurolysin & ACE with Ki 27.76, 3.43, 1.87 μM. Lowers blood pressure, modulates CB1 receptor, reduces pain & food intake.Fórmula:C53H77N13O12Pureza:98%Cor e Forma:SolidPeso molecular:1088.27NESS 0327
CAS:NESS 0327 is a high selectivity antagonist of the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.Fórmula:C24H23Cl3N4OPureza:99.78%Cor e Forma:SolidPeso molecular:489.82CB1R antagonist 2
CB1R antagonist 2 (Compound 11g) functions as an antagonist of the cannabinoid receptor 1 (CB1R), inhibiting the MAPK/NF-κB signaling pathway and exhibiting anti-inflammatory properties. In RAW264.7 cells, it suppresses LPS-induced expression of IL-6, IL-1β, and TNF-α. In murine models, it improves OVA-induced allergic rhinitis.Fórmula:C24H26N4OCor e Forma:SolidPeso molecular:386.492-Arachidonoylglycerol-D5
CAS:2-Arachidonoylglycerol-D5 is the deuterated form of 2-Arachidonoylglycerol (T14011), which acts as an endogenous cannabinoid ligand within the central nervous system.Fórmula:C23H38O4Cor e Forma:SolidPeso molecular:383.58(R)-Zevaquenabant
(R)-Zevaquenabant ((R)-MRI-1867) is the enantiomer of Zevaquenabant. Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual antagonist of the cannabinoid CB1 receptor and inducible nitric oxide synthase (iNOS). It is beneficial in improving chronic kidney disease (CKD) caused by obesity.Cor e Forma:Odour SolidCB1-IN-3
CB1-IN-3 (Compound 6i) is a potent inhibitor of the cannabinoid receptor type 1 (CB1). It holds potential for research in obesity, inflammation, and neurological disorders.Cor e Forma:Odour SolidCalcitonin-13C6,15N4 trifluoroacetic acid
Calcitonin-13C6,15N4 trifluoroacetic acid is a version of calcitonin (salmon) labeled with carbon-13 and nitrogen-15. This hormone regulates calcium and acts dualistically as an agonist to both amylin and calcitonin receptors, promoting bone formation while inhibiting bone resorption.Fórmula:C1401C5H240N4315NO48S2·5C2HF3O2Cor e Forma:SolidPeso molecular:4007.93PSB-SB-1203
CAS:PSB-SB-1203 (Compound 25b) is a dual CB1/CB2 ligand that blocks the CB1 receptor and activates the CB2 receptor with a CB1 Ki of 0.244 μM, a CB2 Ki of 0.210 μM, and an EC50 of 0.054 μM. It shows potential for research in obesity and cancer.Fórmula:C25H30O4Cor e Forma:SolidPeso molecular:394.5d,l-11-Hydroxy-δ-9-THC-D3, 10mg/ml in Methanol
Produto ControladoFórmula:C212H3H27O3Cor e Forma:Single Solution(-)-trans-δ-9-THC-D3 (Dronabinol), 0.1mg/ml in Ethanol
CAS:Produto ControladoCor e Forma:Single Solutiond,l-11-Hydroxy-δ-9-THC-D3, 100mg/ml in Methanol
Produto ControladoFórmula:C212H3H27O3Cor e Forma:Single SolutionCannabinoids Acid/Neutrals Mixture 250 Kit 1000 µg/mL in Acetonitrile
CAS:Produto ControladoCor e Forma:Mixture(-)-δ 9-Tetrahydrocannabinol (δ9-THC) 100 µg/mL in Methanol
CAS:Produto ControladoFórmula:C21H30O2Cor e Forma:Single SolutionPeso molecular:314.46Olivetolic acid 1000 µg/mL in Methanol
CAS:Produto ControladoFórmula:C12H16O4Cor e Forma:Single SolutionPeso molecular:224.25δ8-Tetrahydrocannabinol 250 µg/mL in Acetonitrile
CAS:Produto ControladoFórmula:C21H30O2Cor e Forma:Single SolutionPeso molecular:314.46
