Canabinóides
Os canabinoides são uma classe de compostos químicos diversos derivados de ácidos graxos ou poliquetídeos que atuam sobre os receptores canabinoides nas células, alterando a liberação de neurotransmissores no cérebro. Encontrados principalmente em plantas de cannabis, canabinoides como THC e CBD são amplamente estudados por seus efeitos terapêuticos, incluindo alívio da dor, propriedades anti-inflamatórias e uso potencial em doenças neurodegenerativas. Na CymitQuimica, você encontrará uma ampla variedade de canabinoides para pesquisa em farmacologia, neurobiologia e química medicinal.
Foram encontrados 299 produtos de "Canabinóides"
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CAS:<p>biotinylated anandamide analog acts as a probe for visualizing the accumulation and intracellular trafficking of anandamide</p>Fórmula:C36H60N4O5SPureza:98%Cor e Forma:SolidPeso molecular:660.95VSN-16
CAS:<p>VSN-16, a cannabinoid receptor agonist, is used potentially for the treatment of spasticity in multiple sclerosis.</p>Fórmula:C18H26N2O3Cor e Forma:SolidPeso molecular:318.41ZCZ011
CAS:<p>ZCZ011 enhances CB1 receptor effects, crosses blood-brain barrier, and potentiates cannabimimetic behaviors in mice.</p>Fórmula:C21H18N2O2SPureza:98%Cor e Forma:SolidPeso molecular:362.44OMDM-6
CAS:<p>OMDM-6 is a dual agonist of TRPV1(EC50 = 75 nM) and CB1 (Ki = 3.2 μM). OMDM-6 inhibits anandamide cellular uptake with a Ki of 7.0 μM.</p>Fórmula:C28H42N2O3Pureza:99.66%Cor e Forma:SolidPeso molecular:454.64TC-C 14G
CAS:<p>CB1 receptor inverse agonist</p>Fórmula:C24H17Cl2F2NO4Pureza:98%Cor e Forma:SolidPeso molecular:492.3N-Arachidonyldopamine
CAS:<p>N-Arachidonyldopamine (NADA) is a selective and potent endogenous CB1 receptor agonist (Ki: 250 nM).N-Arachidonyldopamine is also a potent and selective TRPV1</p>Fórmula:C28H41NO3Pureza:97.65%Cor e Forma:SolidPeso molecular:439.63CB1R Allosteric modulator 2
CAS:<p>Compound 18 is a potent CB1R allosteric modulator that acts as a negative modulator (NAM) for CB1R orthosteric ligands.</p>Fórmula:C19H15ClFN3OCor e Forma:SolidPeso molecular:355.79CID1792197
CAS:<p>CID1792197 is a selective agonist of GPR55.</p>Fórmula:C24H23N3O4S2Pureza:98%Cor e Forma:SolidPeso molecular:481.59CB1/2 agonist 2
CAS:<p>CB1/2 agonist 2 binds tightly to cannabinoid receptors, acting fully on CB1 and inversely on CB2.</p>Fórmula:C26H43NO3Cor e Forma:SolidPeso molecular:417.62LEI 101 hydrochloride
CAS:<p>LEI 101 hydrochloride is potent and selective CB2 partial agonist.</p>Fórmula:C23H26ClFN4O4SCor e Forma:SolidPeso molecular:508.99CB2R agonist 1
CAS:<p>CB2R agonist 1 selectively binds human CB2R, EC50 of 0.56 µM, modulates inflammatory cytokines.</p>Fórmula:C22H32N2OCor e Forma:SolidPeso molecular:340.5CB1 inverse agonist 2
CAS:<p>CB1 inverse agonist 2, an oral drug, counters CB1 effects, reducing CP55940-induced hypothermia and anorexia in mice.</p>Fórmula:C24H20ClFN2OSCor e Forma:SolidPeso molecular:438.94(S)-SLV 319
CAS:<p>Ibipinabant (SLV319), a potent CB1 antagonist, K i = 7.8 nM, >1000x selective over CB2, for obesity and diabetic research.</p>Fórmula:C23H20Cl2N4O2SCor e Forma:SolidPeso molecular:487.4CB2 receptor agonist 3
CAS:<p>GP 2A is a selective agonist of CB2 receptor.</p>Fórmula:C24H23Cl2N3OCor e Forma:SolidPeso molecular:440.36KLS-13019
CAS:<p>KLS-13019 is a highly effective and orally active GPR55 receptor antagonist, neuroprotective can reverse chemotherapy-induced peripheral neuropathy (CIPN).</p>Fórmula:C22H29NO3Pureza:>99.99% - >99.99%Cor e Forma:SolidPeso molecular:355.47UCM 707
CAS:<p>endocannabinoid transport inhibitor</p>Fórmula:C25H37NO2Pureza:98%Cor e Forma:SolidPeso molecular:383.57CB2 modulator 1
CAS:<p>CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.</p>Fórmula:C18H19F3N4O2Pureza:99.6%Cor e Forma:SolidPeso molecular:380.36(R)-SLV 319
CAS:<p>(R)-SLV 319: potent CB1 antagonist, K i of 894 nM, dextrorotatory isomer.</p>Fórmula:C23H20Cl2N4O2SCor e Forma:SolidPeso molecular:487.4Palmitoyl serinol
CAS:<p>Anticancer agent 110 is an anticancer compound with cytotoxic, antitumor and antileukemic activities.</p>Fórmula:C19H39NO3Cor e Forma:SolidPeso molecular:329.52AM-1235
CAS:<p>AM-1235 is a potent and selective cannabinoid receptor CB1 agonist.</p>Fórmula:C24H21FN2O3Pureza:97.77%Cor e Forma:SolidPeso molecular:404.43JTE-907
CAS:<p>JTE-907 是一种具有高度选择性和口服活性的 CB2 受体反向激动剂。JTE-907在体内展现出抗炎活性。</p>Fórmula:C24H26N2O6Pureza:99.93%Cor e Forma:SolidPeso molecular:438.47CB2R PAM
CAS:<p>CB2R PAM, an oral drug, boosts CB2 receptor response to specific agonists, showing potential in neuropathic pain relief.</p>Fórmula:C21H24BrFN2O2Pureza:99.09%Cor e Forma:SolidPeso molecular:435.33SCH-336
CAS:<p>SCH-336: potent, selective CB2 agonist (Ki=1.8 nM, EC50=2 nM), orally active, 100x CB2 vs. CB1 preference, reduces leukocyte migration and eosinophilia.</p>Fórmula:C23H25NO8S3Pureza:95.01%Cor e Forma:SolidPeso molecular:539.64CB1R antagonist 1
CAS:<p>CB1R antagonist 1 is a potent CB1R antagonist that can be used to study diseases related to the nervous system.</p>Fórmula:C18H23F3N2O3SPureza:99.65%Cor e Forma:SolidPeso molecular:404.45Nonabine
CAS:<p>Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy.</p>Fórmula:C25H33NO2Pureza:99.46% - 99.95%Cor e Forma:SolidPeso molecular:379.54Taranabant
CAS:<p>Inverse agonist of cannabinoid receptor CB1R. Taranabant was studied for its effect on smoking cessation and inducing weight loss. Serious adverse effects associated with this compound prevented further development as a drug in the clinic.</p>Fórmula:C27H25ClF3N3O2Pureza:Min. 95%Cor e Forma:SolidPeso molecular:515.95 g/molSR144528
CAS:<p>SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM).</p>Fórmula:C29H34ClN3OPureza:99.63%Cor e Forma:SolidPeso molecular:476.05AZD1940
CAS:<p>AZD1940 (UNII-0J0035E9FT) is a high affinity CB(1)/CB(2) receptor agonist of the cannabinoid with oral activity. Application in the study of orofacial pain.</p>Fórmula:C20H29F2N3O2SPureza:98.68%Cor e Forma:SolidPeso molecular:413.52Olorinab
CAS:<p>Olorinab (APD 371) (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist. With an EC50 of 6.2 nM for hCB2.</p>Fórmula:C18H23N5O3Pureza:97.67% - 98.47%Cor e Forma:SolidPeso molecular:357.41CB1 agonist 1
CAS:<p>CB1 agonist 1 is a potent CB1 agonist with a pIC50 value of 5.7 for CB1 receptors.CB1 agonist 1 can be used to study brain disorders, pain, and inflammation.</p>Fórmula:C24H24N2O5SPureza:98.56%Cor e Forma:SolidPeso molecular:452.52PSB-CB5
CAS:PSB-CB5 (GPR18-IN-32)2 is a GRP18 antagonist with anti-inflammatory activity and can be used to study obesity and metabolic disorders.Fórmula:C20H17ClN2O2SPureza:99.26%Cor e Forma:SolidPeso molecular:384.88PSNCBAM-1
CAS:<p>PSNCBAM-1 (PSNCBAM 1) is a CB1 receptor negative allosteric modulator (EC50 = 0.1 μM) with hypophagic effects in vivo.</p>Fórmula:C22H21ClN4OPureza:99.86%Cor e Forma:SolidPeso molecular:392.88Heptadecanoyl ethanolamide
CAS:<p>Heptadecanoyl ethanolamide, an endogenous cannabinoid, serves as a synthetic analog of PEA, featuring an odd-numbered (17-carbon) fatty acid chain [1].</p>Fórmula:C19H39NO2Cor e Forma:SolidPeso molecular:313.52PF-03550096
CAS:<p>PF-03550096, an orally active synthetic cannabinoid (CB), selectively binds to peripheral CB2 receptors with a Ki value of 7.9 nM, demonstrating analgesic activity [1].</p>Fórmula:C19H28N4O4Cor e Forma:SolidPeso molecular:376.45COR659
CAS:<p>COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.</p>Fórmula:C16H16ClNO3SPureza:99.75%Cor e Forma:SolidPeso molecular:337.82Prostaglandin E2-1-glyceryl ester
CAS:<p>Prostaglandin E2-1-glyceryl ester, a member of the Prostaglandin Glycerol Ester family, serves as an endocannabinoid ligand targeting the CB1 receptor. This compound triggers a swift and transient surge in intracellular free calcium levels [1] [2].</p>Fórmula:C23H38O7Cor e Forma:SolidPeso molecular:426.55PSB-SB1202
CAS:<p>PSB-SB1202 (Compound 21a), a phenyl coumarin compound, acts as a CB1/CB2 agonist. It demonstrates EC50 values of 56 and 14 nM and K i values of 32 and 49 nM for CB1 and CB2 receptors, respectively [1].</p>Fórmula:C23H26O4Cor e Forma:SolidPeso molecular:366.45CB2R-IN-1
CAS:<p>CB2R-IN-1 is a potent inverse agonist of the cannabinoid CB2 receptor (Ki: 0.9 nM).</p>Fórmula:C23H27F3N4O6S3Pureza:98%Cor e Forma:SolidPeso molecular:608.67γ-Linolenoyl monoethanolamide
CAS:<p>γ-Linolenoyl monoethanolamide, a fatty N-acyl ethanolamine, acts as an endocannabinoid [1] [2].</p>Fórmula:C20H35NO2Cor e Forma:SolidPeso molecular:321.505PF 514273
CAS:<p>PF 514273 is a CB1 receptor antagonist.</p>Fórmula:C21H17Cl2F2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:452.28GSK494581A
CAS:<p>GSK494581A is a GPR55 agonist and glycine transporter subtype 1 inhibitor.</p>Fórmula:C27H28F2N2O4SPureza:98%Cor e Forma:SolidPeso molecular:514.58URB447
CAS:<p>URB447, a peripherally restricted CB1 cannabinoid antagonist with IC50 values of 313 nM for rat CB1 receptor and 41 nM for human CB2 receptor, effectively reduces food intake and body weight gain in mice. It achieves these effects without penetrating the brain or antagonizing central CB1-dependent responses, making it a potential research tool for obesity studies [1].</p>Fórmula:C25H21ClN2OCor e Forma:SolidPeso molecular:400.9CB-52
CAS:<p>CB-52 acts as a neutral antagonist and ligand for the CB2 cannabinoid receptor [1].</p>Fórmula:C26H43NO3Cor e Forma:SolidPeso molecular:417.62Isopropyl dodec-11-enylfluorophosphonate
CAS:<p>Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester functioning as a central cannabinoid receptor (CB1) antagonist and exhibits</p>Fórmula:C15H30FO2PPureza:98%Cor e Forma:SolidPeso molecular:292.37O-Arachidonoyl glycidol
CAS:<p>O-Arachidonoyl glycidol (compound 1), a 2-arachidonoylglycerol (2-AG) analog, effectively inhibits the hydrolysis of cytosolic 2-oleoylglycerol (2-OG) with an IC50 value of 4.5 µM, and also blocks 2-OG and anandamide hydrolysis in membrane fractions with IC50 values of 19 µM and 12 µM, respectively [1].</p>Fórmula:C23H36O3Cor e Forma:SolidPeso molecular:360.53OMDM-5
CAS:<p>OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).</p>Fórmula:C26H44N2O3Pureza:99.73%Cor e Forma:SolidPeso molecular:432.64AM841
CAS:<p>AM841, a high-affinity electrophilic ligand, covalently interacts with a cysteine residue in helix six, thus activating the CB1 cannabinoid receptor.</p>Fórmula:C26H39NO3SPureza:98%Cor e Forma:SolidPeso molecular:445.66CB-25
CAS:<p>CB-25 is a partial agonist ligand of CB1 cannabinoid receptors, augmenting Forskolin-induced cAMP formation in cancer cells, though not affecting hCB1-CHO cells</p>Fórmula:C25H41NO3Pureza:98%Cor e Forma:SolidPeso molecular:403.6CAY10508
CAS:<p>CAY10508 is a potent and selective inverse agonist for the central cannabinoid (CB1) receptor with therapeutic potential for treating obesity and drug dependence, lacking psychotropic effects. It exhibits a Ki value of 243 nM and an EC50 of 195 nM. At a concentration of 10 µM, CAY10508 displaces [3H]-CP-55,940 with 100% efficacy at the CB1 receptor and 35% at the peripheral cannabinoid (CB2) receptor. Its inverse agonist activity at the CB1 receptor was confirmed through a [35S]-GTPγS binding assay.</p>Fórmula:C21H14Br2N2O2Cor e Forma:SolidPeso molecular:486.2O-2050
CAS:<p>O-2050: strong CB1 antagonist (Ki 2.5 nM), CB2 inhibitor (Ki 0.2 nM); reduces mouse food intake, increases activity.</p>Fórmula:C23H31NO4SPureza:98%Cor e Forma:SolidPeso molecular:417.56
