Canabinóides
Os canabinoides são uma classe de compostos químicos diversos derivados de ácidos graxos ou poliquetídeos que atuam sobre os receptores canabinoides nas células, alterando a liberação de neurotransmissores no cérebro. Encontrados principalmente em plantas de cannabis, canabinoides como THC e CBD são amplamente estudados por seus efeitos terapêuticos, incluindo alívio da dor, propriedades anti-inflamatórias e uso potencial em doenças neurodegenerativas. Na CymitQuimica, você encontrará uma ampla variedade de canabinoides para pesquisa em farmacologia, neurobiologia e química medicinal.
Foram encontrados 368 produtos para "Canabinóides".
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CB1/2 agonist 1
Potent CB1/2 agonist 1; crosses blood-brain barrier; anti-inflammatory, analgesic; for multiple sclerosis research.Fórmula:C21H24BrFN2O2Cor e Forma:SolidPeso molecular:435.33HU-308
CAS:HU-308, a synthetic cannabinoid analogue, is a highly selective agonist of the CB2 receptor. It demonstrates an affinity for the CB2 receptor that is over 440 times greater than its affinity for the CB1 receptor, which are predominantly found in immune cells. This compound plays a crucial role in modulating the immunosuppressive effects of the endocannabinoid system (ECS). Additionally, HU-308 possesses anti-inflammatory and neuroprotective properties, and it regulates the function of microglia. Its potential applications include research into neuroinflammation and retinal diseases.Fórmula:C27H42O3Cor e Forma:SolidPeso molecular:414.62TM38837
CAS:CB1 antagonist 4 is an inverse agonist of cannabinoid receptor 1 (CB1) with an IC50 of 0.4 nM. It can reduce body weight, improve plasma inflammatory markers, and enhance glucose homeostasis [1].Fórmula:C27H20Cl2F3N7OCor e Forma:SolidPeso molecular:586.40HU 433
CAS:HU 433, a synthetic cannabinoid, acts as a CB2 receptor agonist and is an enantiomer of HU 308. It provides anti-inflammatory and neuroprotective effects by binding to the CB2 receptor, primarily found on immune cells, thereby modulating immune responses and inflammation. Additionally, HU 433 influences microglial signaling pathways, particularly LPS and IFNγ-mediated routes, affecting the phosphorylation of MAPKs, including ERK1/2, JNK, p38, and Akt. This compound is valuable in researching neuroinflammation and retinal diseases.Fórmula:C27H42O3Cor e Forma:SolidPeso molecular:414.62AM8936
AM8936: potent CB1 agonist, EC50 rCB1=8.6nM/hCB1=1.4nM, Ki rat CB1=0.55nM; potential for CNS, metabolic, pain, glaucoma research.Fórmula:C25H33NO3Cor e Forma:SolidPeso molecular:395.53BNS808
CAS:BNS808 is an orally active, selective CB1R antagonist with an IC50 of 0.8 nM, demonstrating significant selectivity for CB2R and minimal brain penetration. It is being studied for the treatment of obesity and related metabolic complications, such as metabolic dysfunction-associated steatotic liver disease (MASLD). BNS808 reduces drug exposure to the central nervous system, enhancing safety, and minimizes drug interactions through high plasma protein binding.Fórmula:C25H20Cl3N3O3SCor e Forma:SolidPeso molecular:548.869MDMB-FUBICA
CAS:MDMB-FUBICA is a potent agonist of the cannabinoid receptors and exhibits psychoactive properties. It can be utilized in e-cigarettes.Fórmula:C23H25FN2O3Cor e Forma:SolidPeso molecular:396.455Taranabant
CAS:Taranabant: potent CB1 receptor inverse agonist; inhibits agonists with 0.13 nM Ki in vitro.Fórmula:C27H25ClF3N3O2Pureza:99.06% - 99.06%Cor e Forma:SolidPeso molecular:515.96Virodhamine hydrochloride
CAS:Virodhamine (hydrochloride) acts as a partial agonist of the cannabinoid CB1 receptor and a full agonist of the cannabinoid CB2 receptor.Fórmula:C22H38ClNO2Cor e Forma:SolidPeso molecular:384.00Bzo-poxizid
CAS:Bzo-poxizid is a synthetic cannabinoid and a psychoactive substance.Fórmula:C20H21N3O2Cor e Forma:SolidPeso molecular:335.40CB1/2 receptor-1
CAS:CB1/2 receptor-1 (compound 5.3) serves as an agonist for CB1/2 receptors and is utilized in angiogenesis research.Fórmula:C33H48O2Cor e Forma:SolidPeso molecular:476.73MDA7
CAS:MDA7 is a selective agonist of the cannabinoid receptor 2 (CB2), demonstrating an EC50 of 128 nM in human CB2 receptors and 67.4 nM in rat CB2 receptors. The compound exhibits good affinity for CB2 receptors, with Ki values of 422 nM for humans and 238 nM for rats. In rat models, MDA7 shows analgesic activity.Fórmula:C22H25NO2Cor e Forma:SolidPeso molecular:335.439CB2 receptor antagonist 1
CAS:Compound 29 is a potent, CB2-selective antagonist/reverse agonist. Derivatives 23 & 24 offer antinociception; 24 activates cannabinoid/TRPV1 receptors.Fórmula:C28H47NO3Cor e Forma:SolidPeso molecular:445.68BAY 38-7271
CAS:BAY 38-7271: potent neuroprotective, selective CB1/CB2 agonist, Ki of 1.85 nM (CB1) & 5.96 nM (CB2).Fórmula:C20H21F3O5SPureza:98%Cor e Forma:SolidPeso molecular:430.44AB-FUBINACA 3-fluorobenzyl isomer
CAS:AB-FUBINACA 3-fluorobenzyl isomer is a synthetic cannabinoid and an indazole derivative, exhibiting high affinity for central CB1 receptors (Ki= 0.9 nM) and possessing anticonvulsant activity.Fórmula:C20H21FN4O2Cor e Forma:SolidPeso molecular:368.41MDA77
CAS:MDA77 is a CB2 agonist with an EC50 value of 5.82 nM and exhibits no activity towards CB1.Fórmula:C21H23N3O3Cor e Forma:SolidPeso molecular:365.431'-Naphthoyl-2-methylindole
CAS:1'-Naphthoyl-2-methylindole (Compound 88) acts as a cannabinoid mimic and an inhibitor of Win 55212-2, displaying a 34% inhibition of [3H]Win 55212-2 binding to cannabinoid receptors at a concentration of 3 μM.Fórmula:C20H15NOCor e Forma:SolidPeso molecular:285.34Cryolite (Na3(AlF6))
CAS:Produto ControladoFórmula:AlF6Na3Pureza:99.9%Cor e Forma:SolidPeso molecular:209.9413Ref: IN-DA001MYR
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