Nucleotídeos
Os nucleotídeos são compostos orgânicos que servem como building blocks dos ácidos nucleicos, essenciais para a formação de DNA e RNA. Cada nucleotídeo é composto por uma base nitrogenada, uma molécula de açúcar e um ou mais grupos fosfato. Esses nucleotídeos se unem para formar longas cadeias, criando o material genético que carrega e transmite informações genéticas em todos os organismos vivos. Nesta seção, você encontrará uma ampla variedade de nucleotídeos cruciais para pesquisas em genética, biologia molecular e bioquímica. Eles são fundamentais para estudar processos genéticos, sintetizar ácidos nucleicos e desenvolver ferramentas diagnósticas e terapêuticas. Na CymitQuimica, oferecemos nucleotídeos de alta qualidade para apoiar suas pesquisas científicas e aplicações, garantindo precisão e confiabilidade em seus experimentos.
Subcategorias de "Nucleotídeos"
Foram encontrados 2637 produtos de "Nucleotídeos"
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Thymidine-5'-diphosphate-L-rhamnose disodium
CAS:Thymidine-5'-diphosphate-L-rhamnose disodium is a nucleoside that belongs to the class of modified nucleosides. It is a synthetic, modified thymidine with a phosphate group at the 5'-position and L-rhamnose at the 2' position. Thymidine-5'-diphosphate-L-rhamnose disodium has antiviral and anticancer activities, as well as high purity and high quality. This compound has been shown to inhibit HIV replication in vitro and in vivo. Thymidine-5'-diphosphate-L-rhamnose disodium is also used in the synthesis of DNA and RNA.Fórmula:C16H24N2O15P2Na2Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:592.29 g/mol2'-Azido-2'-deoxyadenosine
CAS:2'-Azido-2'-deoxyadenosine is a synthetic nucleoside analog of adenosine in which the 2'-hydroxyl group of the ribose sugar is replaced by an azido group (–N₃), and the 3'- and 5'-hydroxyl groups remain intact. This modification confers unique chemical properties, including the ability to participate in bioorthogonal "click" chemistry reactions, particularly azide-alkyne cycloadditions, making it useful for labeling and tracking nucleic acids in biochemical studies. Additionally, the azido substitution can influence enzymatic recognition and incorporation by polymerases, allowing its use in studying nucleic acid metabolism, drug design, and therapeutic nucleoside analog development.Fórmula:C10H12N8O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:292.25 g/mol2'-C-Methyluridine
CAS:2'-C-Methyluridine is a synthetic nucleoside analog derived from uridine, modified with a methyl group at the 2'-carbon of the ribose sugar. This small chemical change has important implications for RNA biology, antiviral drug development, and biochemical research, especially in targeting RNA viruses.Fórmula:C10H14N2O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:258.23 g/mol5'-O-DMT-5-[N-(6-(trifluoroacetamido)hexyl)-3-E-acrylamido]-2'-deoxyuridine
CAS:5'-O-DMT-5-[N-(6-(trifluoroacetamido)hexyl)-3-E-acrylamido]-2'-deoxyuridine is a novel phosphoramidate nucleoside monophosphate, which is a phosphate analog of 2'-deoxyuridine. It has been shown to be an activator for DNA polymerases and is able to inhibit the replication of DNA in vitro. It also has antiviral properties, as it inhibits the synthesis of viral RNA. 5'-O-DMT-5-[N-(6-(trifluoroacetamido)hexyl)-3-E-acrylamido]-2'-deoxyuridine also has anti-inflammatory effects, as it inhibits prostaglandin synthesis.Fórmula:C41H45F3N4O9Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:794.83 g/mol3'-O-Methylcytidine
CAS:3'-O-Methylcytidine is an acidic guanine nucleoside that is a component of RNA. It is a biochemical building block and a co-substrate in the synthesis of DNA and RNA. 3'-O-Methylcytidine has been shown to be hydroxylated by the enzyme cytidine 5'-monophosphate, which leads to its termination when it reaches the ribosome. This nucleoside also inhibits bacterial growth through inhibition of ribosomal function, leading to reduced protein synthesis. 3'-O-Methylcytidine can act as an environmental pollutant, especially in chloride environments such as seawater. It has been found to be globally distributed in dinucleotides and monomethylated forms, with biosynthetic pathways similar to other nucleic acids.
Fórmula:C10H15N3O5Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:257.24 g/molADP monosodium salt - Bio-X ™
CAS:Adenosine 5'-diphosphate monosodium salt (ADP) is an adenine nucleotide which is phosphorylated into ATP by the enzyme ATPase. This phosphorylation is essential in cellular homeostasis due to its role in energy storage and nucleic acid metabolism.
Fórmula:C10H15N5O10P2•NaPureza:Min. 95%Cor e Forma:PowderPeso molecular:449.18 g/mol2'-Deoxy-5'-O-DMT-2'-fluoro-N4-phenoxyacetylcytidine
2'-Deoxy-5'-O-DMT-2'-fluoro-N4-phenoxyacetylcytidine is a monophosphate nucleotide analog that is used as an antiviral agent. It inhibits viral replication by inhibiting the activity of DNA polymerase, which is needed to synthesize DNA. 2'-Deoxy-5'-O-DMT-2'-fluoro-N4-phenoxyacetylcytidine has been shown to be effective against HIV and HSV in vitro and in vivo. This nucleotide analog has also been shown to be potent against Hepatitis B viruses and adenovirus type 3.
2'-Deoxy-5'-O-DMT-2'-fluoro-N4-phenoxyacetylcytidine is phosphoramidate derivative of cytosine with a fluorine substitution at the 2' position on the sugar moiety, making it a novel compound. The pyridFórmula:C38H36FN3O8Pureza:Min. 98 Area-%Cor e Forma:Yellow PowderPeso molecular:681.71 g/mol2'-Deoxy-5-propynylcytidine
CAS:Deoxynucleoside with an alkyne handle on the base which can be used for conjugation via click chemistry.Fórmula:C12H15N3O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:265.27 g/mol2'-Deoxyguanosine 3'-monophosphate sodium
CAS:2'-Deoxyguanosine 3'-monophosphate sodium is a novel, synthetic nucleoside that inhibits DNA replication and transcription. It has been shown to be a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) and human T-cell leukemia virus type I (HTLV-I). 2'-Deoxyguanosine 3'-monophosphate sodium is in the category of nucleosides, which are phosphorylated compounds that can be incorporated into DNA by DNA polymerase. This product has a high purity and is synthesized from diphosphate.Fórmula:C10H12Na2N5O7PPureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:391.19 g/molN-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt
CAS:N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt is a novel modified nucleoside with anticancer activity. The compound is a monophosphate, which activates DNA and RNA synthesis. This agent also has antiviral and antifungal effects. N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt is synthesized from diphosphate and deoxyribonucleosides. It was first patented in 1979 and has been approved by the US Food and Drug Administration (FDA) for use as a pharmaceutical agent. N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt can be used to produce phosphoramidites, which are synthetic DNA building blocks that are used in the production of DNA and RNA synthesis.Fórmula:C13H16N4O9Na2Pureza:Min. 95 Area-%Cor e Forma:Off-White PowderPeso molecular:418.27 g/mol1-(3',5'-Di-O-benzoyl-2'-chloro-2'-deoxy-beta-L-arabinofuranosyl)thymine
CAS:1-(3`,5`-Di-O-benzoyl-2`-chloro-2`-deoxy-beta-L-arabinofuranosyl)thymine is a nucleoside analog for research applications. This compound is made up of a thymine base and the sugar 2'-Chloro-2'-deoxy-β-L-arabinofuranose. The sugar has the L-arabinose configuration and a 2'-Chloro substitution which can alter its interactions with enzymes and enhance resistance to degradation. It also contains benzoyl groups that protect the hydroxyls during chemical synthesis.
Fórmula:C24H21FN2O7Pureza:Min. 95%Peso molecular:468.43 g/molUridine-5-oxyacetic acid methyl ester
CAS:Uridine-5-oxyacetic acid methyl ester is a modified nucleotide that is an intermediate in the biosynthesis of uridine. This molecule can be synthesized from 5-hydroxymethyluridine and malonic acid by a methyltransferase. Uridine-5-oxyacetic acid methyl ester can also be obtained from the metabolism of deoxyribose. Analysis of this molecule is possible with spectrometric, mass spectrometric, and chemical structures methods. It has been shown to have a function in translation and protein synthesis. The chemical structure of uridine-5-oxyacetic acid methyl ester has been determined to be guanosine-3',5'-bis(2'-carboxyethyl)phosphate, which is different from that found in DNA or RNA.Fórmula:C12H16N2O9Pureza:Min. 95%Cor e Forma:PowderPeso molecular:332.26 g/mol2'-O-Methyl-5-propynylcytidine
CAS:2'-O-Methyl-5-propynylcytidine is an antiviral drug that inhibits the replication of retroviruses by competitive inhibition of the viral RNA polymerase. It has been shown to be effective against HIV, HSV and CMV. This drug also has shown anticancer activity in vitro and in vivo. 2'-O-Methyl-5-propynylcytidine has a novel mechanism of action and is used as a building block for oligonucleotide synthesis because it is resistant to degradation by nucleases.Fórmula:C13H17N3O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:295.29 g/molRiboflavin 5'-adenosine diphosphate disodium salt hydrate
CAS:Riboflavin 5'-adenosine diphosphate disodium salt hydrate is a chemical compound that can be used as a substrate for nitrate reductase in the presence of molecular oxygen. It can be used to identify mollicutes and diagnose radiation-induced lesions. The reaction mechanism involves the conversion of riboflavin 5'-adenosine monophosphate to riboflavin 5'-adenosine diphosphate by an enzyme called nitrate reductase, which is present in the microorganism. This reaction is accompanied by the release of electrons, which are detected by a fluorescence detector. The rate constant for this reaction is k=1.5x10^-4/s at pH 7 and 37 degrees Celsius with an electrochemical detector and k=2.0x10^-3/s at pH 7 and 37 degrees Celsius with a carbonyl oxygens detector. Riboflavin 5'-Fórmula:C27H31N9Na2O15P2·xH2OPureza:(Uv) Min. 95%Cor e Forma:Yellow Orange PowderPeso molecular:829.51 g/mol2'-Deoxy-N2-DMF-5'-O-DMT-guanosine
CAS:2'-Deoxy-N2-DMF-5'-O-DMT-guanosine is a monophosphate nucleoside that has antiviral, anticancer, and high purity properties. It is synthesized by the phosphoramidite method from 2'-deoxy-N2-DMF and 5'-O-DMT guanosine. This compound has been shown to inhibit the growth of human cancer cells in vitro and in vivo. It also inhibits HIV replication in vitro and is not toxic to normal cells.Fórmula:C34H36N6O6Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:624.7 g/mol1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil
CAS:1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil is a nucleoside analog and contains a uracil base, and a 2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl sugar moiety. The 2'-fluoro modification is of particular interest due to its potential to alter the chemical and biological properties of the resulting oligonucleotides. Fluorinated nucleosides and their analogs have been extensively studied for their antiviral and anticancer activities. The incorporation of fluorine into nucleoside analogs can also affect their interaction with DNA and RNA, leading to changes in their therapeutic potential.Fórmula:C30H29FN2O7Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:548.56 g/mol1-Methylpseudouridine
CAS:1-Methylpseudouridine is a substitute for uridine in modified mRNA. This substitution has shown to increase transfection by reducing immuogenicity. The 1-methylpseudouridine substituted mRNA increases protein expression due to low immune stimulation as it evades detection by the edosomal Toll-like receptor (TLR3).Fórmula:C10H14N2O6Pureza:Min. 98.0 Area-%Peso molecular:258.23 g/molRef: 3D-M-4320
1gA consultar5gA consultar250mgA consultar500mgA consultar2500mgA consultar-Unit-ggA consultar1-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)-5-iodouracil
CAS:1-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)-5-iodouracil is a nucleoside analog with antiviral properties. It consists of a modified uracil base (5-iodouracil) attached to a fluorinated arabinofuranosyl sugar moiety. In cell culture, it inhibits the replication of varicella-zoster virus, herpes simplex virus type 1 and 2 and cytomegalovirus.Fórmula:C9H10FIN2O5Pureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:372.09 g/mol9-(b-D-Ribofuranosyl)purine
CAS:9-(b-D-Ribofuranosyl)purine (9-BRP) is a purine nucleoside that is used in the synthesis of dyes. It has been shown to be an effective inhibitor of the enzyme phosphodiesterase 3B, which breaks down cyclic adenosine monophosphate (cAMP), and therefore can prevent kidney fibrosis. 9-BRP has also been shown to inhibit the synthesis of collagen by binding to cAMP. In addition, 9-BRP binds to DNA and forms hydrogen bonds with nitrogen atoms on the phosphate groups in DNA. This interaction prevents the formation of hydrogen bonds between water molecules in water vapor and phosphate groups, thus slowing down their rate of dissociation from each other. 9-BRP also has a high affinity for Toll-like receptor 4 (TLR4), which is involved in the inflammatory response, making it an ideal therapeutic candidate for treating inflammation and renal fibrosis.Fórmula:C10H12N4O4Pureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:252.23 g/molb-Nicotinamide mononucleotide
CAS:b-Nicotinamide mononucleotide, or NMN, is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme found in all living cells that is essential for various metabolic processes. NAD+ is involved in critical functions such as DNA repair, gene expression, and cellular stress responses.Fórmula:C11H15N2O8PPureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:334.22 g/mol
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