Nucleotídeos
Os nucleotídeos são compostos orgânicos que servem como building blocks dos ácidos nucleicos, essenciais para a formação de DNA e RNA. Cada nucleotídeo é composto por uma base nitrogenada, uma molécula de açúcar e um ou mais grupos fosfato. Esses nucleotídeos se unem para formar longas cadeias, criando o material genético que carrega e transmite informações genéticas em todos os organismos vivos. Nesta seção, você encontrará uma ampla variedade de nucleotídeos cruciais para pesquisas em genética, biologia molecular e bioquímica. Eles são fundamentais para estudar processos genéticos, sintetizar ácidos nucleicos e desenvolver ferramentas diagnósticas e terapêuticas. Na CymitQuimica, oferecemos nucleotídeos de alta qualidade para apoiar suas pesquisas científicas e aplicações, garantindo precisão e confiabilidade em seus experimentos.
Subcategorias de "Nucleotídeos"
Foram encontrados 2634 produtos de "Nucleotídeos"
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7-Deaza-7-iodoadenosine
CAS:<p>7-Deaza-7-iodoadenosine is a nucleotide that has been used in experiments to assess the levels of adenosine, a dinucleotide phosphate that is involved in many cellular functions. 7-deaza-7-iodoadenosine has been shown to inhibit locomotor activity in rats and cyclase activity in 3T3-L1 preadipocytes. It also inhibits the release of inflammatory proteins from polymorphonuclear leucocytes and angiogenesis (formation of new blood vessels) in liver cells. Although this nucleotide has not been extensively studied, it has been proposed as an antiinflammatory agent because it inhibits protein synthesis and downregulates proinflammatory proteins.</p>Fórmula:C11H13IN4O4Pureza:Min. 95%Peso molecular:392.15 g/mol5-Isopropyl-2'-deoxyuridine
CAS:<p>5-Isopropyl-2'-deoxyuridine is a nucleoside analog that is used in the treatment of inflammatory bowel disease. It has been shown to be effective in the treatment of Crohn's disease, ulcerative colitis, and indeterminate colitis. 5-Isopropyl-2'-deoxyuridine inhibits bacterial growth by inhibiting RNA synthesis, which leads to cell death. This drug also inhibits the production of inflammatory mediators such as prostaglandins and leukotrienes that are released from cells infected with bacteria. 5-Isopropyl-2'-deoxyuridine is converted into an active form by hydrolysis or oxidation followed by phosphorylation. This drug binds to the 5' end of bacterial DNA and prevents the formation of hydrogen bonds between adjacent bases, causing strand breakage.</p>Fórmula:C12H18N2O5Pureza:Min. 95%Peso molecular:270.28 g/mol2',3'-Dideoxyadenosine-5'-triphosphate lithium salt
CAS:<p>2',3'-Dideoxyadenosine-5'-triphosphate lithium salt is a nucleoside for use in research applications</p>Fórmula:C10H16N5O11P3·xLiPureza:Min. 95%Cor e Forma:Clear liquid.Peso molecular:475.18 g/molCytidine 5’-phosphoromorpholidate N,N’-dicyclohexyl-4-morpholinecarboximidamide
CAS:<p>Cytidine 5’-phosphoromorpholidate N,N’-dicyclohexyl-4-morpholinecarboximidamide is a novel cytidine phosphoramidate monophosphate that has been shown to have anticancer and antiviral properties. It can be used as a DNA nucleoside phosphoramidite in the synthesis of oligonucleotides or as an antiviral agent by inhibiting viral RNA replication. Cytidine 5’-phosphoromorpholidate N,N’-dicyclohexyl-4-morpholinecarboximidamide is chemically synthesized in high purity and quality for use in research in the field of DNA, nucleosides, and antiviral agents.</p>Fórmula:C30H52N7O9PPureza:Min. 95%Peso molecular:685.75 g/mol5-Carboxymethylaminomethyl- 2'-O-methyluridine
CAS:<p>5-Carboxymethylaminomethyl- 2'-O-methyluridine (5CmAMU) is a modified nucleobase that is categorized as a modified base. It is an analog of uridine, which has been shown to be effective against tuberculosis in mice. 5CmAMU inhibits the methylation of rRNA and DNA by binding to the enzyme RNA methyltransferase, thereby inhibiting transcription and replication. This modification has also been shown to inhibit cellular proliferation and promote apoptosis. 5CmAMU binds to guanine with a stoichiometry of 1:1, which provides evidence for its role in DNA synthesis and repair. The structural modifications on this molecule may lead to diagnostic applications or treatments for diseases such as tuberculosis.</p>Fórmula:C13H19N3O8Pureza:Min. 95%Cor e Forma:PowderPeso molecular:345.31 g/molFialuridine 5'-monophosphate
CAS:<p>Fialuridine 5'-monophosphate is an analog of fialuridine, a drug used to treat HIV. Fialuridine 5'-monophosphate inhibits mitochondrial DNA synthesis by inhibiting hepg2 in the mitochondria and blocks the conversion of uracil to thymine in nuclear DNA. The inhibition of these two processes prevents viral replication and cell division. Fialuridine 5'-monophosphate also has antioxidant properties that protect cells from oxidative damage induced by reactive oxygen species. This drug may be beneficial for cancer treatment as well as hepatitis C or herpes simplex virus infection.</p>Fórmula:C9H11FIN2O8PPureza:Min. 95%Peso molecular:452.07 g/mol2'-O-Methylcytidine 5'-triphosphate lithium - 100mM aqueous solution
CAS:<p>2'-O-Methylcytidine 5'-triphosphate lithium is a synthetic nucleotide</p>Fórmula:C10H18N3O14P3•LixPureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:497.18 g/mol6-(Benzylamino)-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS:<p>6-(Benzylamino)-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione (BMPT) is a synthetic cytokinin that belongs to the group of 6-benzylaminopurines. BMPT is an inhibitor of cytokinin receptor kinases, as it is a benzyl uracil derivative. BMPT can be used as a building block for the synthesis of other compounds and has been used as an inhibitor of cell growth in various organisms.</p>Fórmula:C12H13N3O2Pureza:Min. 95%Peso molecular:231.25 g/mol9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine
CAS:<p>9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine is a modified nucleoside that is used as an antiviral and anticancer agent. It acts as an activator for the synthesis of DNA, RNA, and protein. 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine also inhibits the growth of cancer cells by interfering with the division process. This drug is synthesized from 9-(5'-deoxy-5'-iodo-b-D-ribofuranosyl) -2,6 difluoro adenine (diFdA). The Ribonucleosides are then prepared in a similar manner to other nucleosides by using phosphoramidites. The product is then purified using HPLC.</p>Fórmula:C10H11F2N5O3Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:287.23 g/mol2'-O-Methylguanosine 5'-triphosphate lithium salt - 100mM aqueous solution
CAS:<p>2'-O-Methylguanosine 5'-triphosphate lithium salt is a synthetic nucleotide</p>Fórmula:C11H18N5O14P3·xLiPureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:537.21 g/mol2-Methylthio-N6-methyladenosine
CAS:<p>2-Methylthio-N6-methyladenosine is an adenosine nucleoside that is found in the DNA of eukaryotes. It is similar to 2-methylthio-n6-isopentenyladenosine, which is a modified form of n6-methyladenosine. The chemical structures of both molecules are related to the thermodynamic properties of the molecule and their ability to be postsynthetically modified. These modifications can lead to changes in their translation, which can have implications for the development and progression of disease. 2-Methylthio-N6-methyladenosine has a role in epigenetics, which is defined as changes in gene expression without any alterations in DNA sequence. In this case, it may modify the chloride ion concentration by changing its chemical structure, leading to epigenetic changes that can affect how genes are expressed or translated into proteins.</p>Fórmula:C12H17N5O4SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:327.36 g/mol8-(p-Chlorophenylthio)-cGMP
CAS:<p>8-(p-Chlorophenylthio)-cGMP is a modified nucleoside that has anticancer activity. It inhibits DNA synthesis and the activation of protein kinases, which are enzymes that transmit signals from the cell surface to the nucleus. 8-(p-Chlorophenylthio)-cGMP can also inhibit viral replication by inhibiting the production of new virus particles and by inhibiting the action of reverse transcriptase, an enzyme that converts RNA into DNA.</p>Fórmula:C16H15ClN5O7PSPureza:Min. 95%Peso molecular:487.81 g/mol8-Aminoguanosine
CAS:<p>8-Aminoguanosine is a synthetic purine nucleoside that inhibits DNA synthesis. It has been shown to inhibit the proliferation of HL-60 cells, which are a model for human monocytes and neutrophils. 8-Aminoguanosine has been shown to bind to the template strand of DNA and inhibit the incorporation of deoxyribonucleotide triphosphates into the newly synthesized strand. This binding prevents DNA replication by preventing access to the template strand of DNA. 8-Aminoguanosine inhibits cyclin D2, an enzyme required for cell division, at concentrations as low as 0.1 mM, and it also inhibits microtubule assembly. 8-Aminoguanosine has shown in vitro activity against various tumor cell lines including Molt-4 and MCF7 cells, and in vivo activity in a mouse model against C3H/HeJ mice transplanted with Lewis lung carcinoma cells.</p>Fórmula:C10H14N6O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:298.26 g/mol6-Chloro-2-iodo-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
CAS:<p>6-Chloro-2-iodo-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a protected purine nucleoside</p>Fórmula:C16H16ClIN4O7Pureza:Min. 95%Peso molecular:538.68 g/mol5-Methylcytidine
CAS:<p>5-Methylcytidine is a methyltransferase enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine to 5-methylcytosine. This reaction is essential for DNA replication and repair. 5-Methylcytidine has been shown to be an important factor in the regulation of mitochondrial functions, as well as other cellular processes such as protein synthesis, nuclear DNA replication, and tumor suppression. It also has been shown to inhibit the replication of murine sarcoma virus and Toll-like receptor. 5-Methylcytidine can be used in chemotherapy treatment against mouse tumors and murine sarcoma virus by preventing viral RNA synthesis with monoclonal antibodies.</p>Fórmula:C10H15N3O5Peso molecular:257.24 g/molRef: 3D-W-201877
25gA consultar50gA consultar100gA consultar250gA consultar500gA consultar-Unit-ggA consultar5′-O-DMT-LNA N-dmf guanosine
CAS:<p>5′-O-DMT-LNA N-dmf guanosine is a modified nucleoside that has anticancer, antiviral, and anti-inflammatory activities. It binds to the ribonucleotide reductase enzyme, which is an enzyme required for the production of new DNA and RNA. This binding prevents the synthesis of new DNA and RNA in cells, leading to cell death. 5′-O-DMT-LNA N-dmf guanosine has been shown to be active against cancer cells in vitro and in vivo. In addition, it also inhibits replication of human immunodeficiency virus type 1 (HIV) by binding to reverse transcriptase (RT), which is an enzyme critical for HIV replication.</p>Fórmula:C35H36N6O7Pureza:Min. 95%Peso molecular:652.7 g/mol5,6-Dihydrothymidine
CAS:<p>5,6-Dihydrothymidine is a hydroxylated thymidine analogue. It binds to the leukocyte antigen, which is found on many different types of cells. 5,6-Dihydrothymidine inhibits the replication of herpes simplex virus and can be used for diagnostic purposes. 5,6-Dihydrothymidine has been shown to have conformational properties that are similar to those of thymine, which allows it to bind to the template strand in DNA. This binding prevents the synthesis of messenger RNA from DNA. 5,6-Dihydrothymidine is also able to inhibit cell growth in culture and can be used as a cell culture medium supplement.</p>Fórmula:C10H16N2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:244.24 g/mol2',3',5'-Triacetyl -azacytidine
CAS:<p>2',3',5'-Triacetyl-azacytidine is a transcription factor that has dose-dependent effects on the production of melanin. It inhibits the synthesis of melanin by binding to two specific transcription factors, the microphthalmia-associated transcription factor and the histone methyltransferases. This drug also inhibits tyrosinase, which is an enzyme involved in the production of melanin. 2',3',5'-Triacetyl-azacytidine has been shown to inhibit the growth of murine melanoma cells and may be useful for treating skin cancer.</p>Fórmula:C14H18N4O8Pureza:Min. 95%Peso molecular:370.31 g/mol2-O-Ethylthymidine
CAS:<p>2-O-Ethylthymidine is a nucleoside that is used to study the structure and dynamics of DNA. It can be synthesized by reacting 1-β-D-arabinofuranosylbenzene with ethylmercury acetate. 2-O-Ethylthymidine can be used in kinetic studies as it is specific for dna. It has been shown to have a conformational change, which is stabilized by the presence of an aromatic ring such as phenanthrene. This compound was also found to inhibit neuroblastoma cell growth in vitro.</p>Fórmula:C12H18N2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:270.28 g/mol2-Amino-9-(2'-deoxy-β-D-ribofuranosyl)purine
CAS:<p>2-Amino-9-(2'-deoxy-b-D-ribofuranosyl)purine is a nucleoside analog that has been found to be effective in the treatment of leukemia.</p>Fórmula:C10H13N5O3Pureza:(Hplc) Min. 98.00%Cor e Forma:PowderPeso molecular:251.24 g/mol
