Nucleotídeos
Os nucleotídeos são compostos orgânicos que servem como building blocks dos ácidos nucleicos, essenciais para a formação de DNA e RNA. Cada nucleotídeo é composto por uma base nitrogenada, uma molécula de açúcar e um ou mais grupos fosfato. Esses nucleotídeos se unem para formar longas cadeias, criando o material genético que carrega e transmite informações genéticas em todos os organismos vivos. Nesta seção, você encontrará uma ampla variedade de nucleotídeos cruciais para pesquisas em genética, biologia molecular e bioquímica. Eles são fundamentais para estudar processos genéticos, sintetizar ácidos nucleicos e desenvolver ferramentas diagnósticas e terapêuticas. Na CymitQuimica, oferecemos nucleotídeos de alta qualidade para apoiar suas pesquisas científicas e aplicações, garantindo precisão e confiabilidade em seus experimentos.
Subcategorias de "Nucleotídeos"
Foram encontrados 2634 produtos de "Nucleotídeos"
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Xanthosine-5'-triphosphate triethylammonium salt - 100 mM aqueous solution
CAS:<p>Inhibitor of adenylyl and guanylyl cyclase</p>Fórmula:C10H15N4O15P3·xC6H15NPureza:Min. 95%Cor e Forma:Colorless PowderPeso molecular:524.17 g/mol2-Fluoroadenosine
CAS:<p>2-Fluoroadenosine is a nucleoside that has shown high resistance to the enzyme cyclase. This property may be due to its structural and conformational properties, which are different from those of adenosine. 2-Fluoroadenosine has been shown to inhibit the synthesis of ATP in ventricular myocardium and fat cells, as well as increase levels of adenylate kinase in blood. It has also been shown to have potential as a drug target for autoimmune diseases, such as multiple sclerosis. 2-Fluoroadenosine can be used for biochemical and pharmacokinetic studies because it is rapidly metabolized by the liver and excreted in urine.<br>2-Fluoroadenosine can also be used to measure changes in the ratio of adenylate kinase:adenylate kinase reductase (AKAR) in blood plasma.</p>Fórmula:C10H12FN5O4Pureza:Min. 95%Cor e Forma:White Slightly Yellow PowderPeso molecular:285.23 g/molStearoyl coenzyme A free acid hydrate
CAS:<p>Stearoyl coenzyme A free acid hydrate is a natural, non-synthetic lipid molecule that belongs to the group of fatty acids. It is found in the form of a white crystalline powder and has a melting point at approximately 56°C. Stearoyl CoA free acid hydrate is an essential component of cellular metabolism, carrying out reactions such as desaturase, dextran sulfate, and other enzyme activities. Stearoyl CoA free acid hydrate may have therapeutic applications for metabolic disorders and obesity. The enzyme complex that catalyzes the synthesis of stearoyl CoA free acid hydrate in adipocytes is ATP-binding cassette transporter (ABC) A1 and ABCG1, which are members of the superfamily of ATP-binding cassette (ABC) transporters. It also plays a role in regulating immune responses via Toll-like receptor 4 (TLR4).</p>Fórmula:C39H70N7O17P3S•H2OPureza:Min. 92 Area-%Cor e Forma:White PowderPeso molecular:1,052.01 g/molN6-(6-Aminohexyl)-2'-deoxyadenosine
CAS:<p>N6-(6-Aminohexyl)-2'-deoxyadenosine is a novel nucleoside that is structurally related to the natural nucleosides, dATP and dGTP. It has been shown to be an activator of ribonucleosides and phosphoramidites, which are used in the synthesis of DNA and RNA. N6-(6-Aminohexyl)-2'-deoxyadenosine has also been shown to inhibit cancer cells as well as antiviral activity against HIV-1.</p>Fórmula:C16H26N6O3Pureza:Min. 95%Cor e Forma:Slightly Yellow PowderPeso molecular:350.43 g/mol2'-Deoxy-N2-methylguanosine
CAS:<p>2'-Deoxy-N2-methylguanosine is a nucleoside with anticancer properties. It is a phosphoramidite, which is an analog of the natural nucleotide guanosine, where the 2'-hydroxyl group has been replaced by a methylene group. This compound is used in DNA synthesis and RNA synthesis. It can be used as a monophosphate or diphosphate. It also has antiviral and anti-inflammatory activities, as well as N2-methylamino moiety that can be used for the treatment of cancer and inflammatory diseases such as arthritis.</p>Fórmula:C11H15N5O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:281.27 g/mol2-Amino-9-(2'-deoxy-β-D-ribofuranosyl)purine
CAS:<p>2-Amino-9-(2'-deoxy-b-D-ribofuranosyl)purine is a nucleoside analog that has been found to be effective in the treatment of leukemia.</p>Fórmula:C10H13N5O3Pureza:(Hplc) Min. 98.00%Cor e Forma:PowderPeso molecular:251.24 g/mol7-Deaza-2',3'-dideoxy-7-iodoadenosine
CAS:<p>7-Deaza-2',3'-dideoxy-7-iodoadenosine is a nucleoside analogue that is used as an antiviral, anticancer, and antifungal agent. It is a modified form of adenosine which inhibits viral replication by inhibiting the activity of reverse transcriptase. 7-Deaza-2',3'-dideoxy-7-iodoadenosine has also been shown to inhibit DNA synthesis in cells by blocking the incorporation of dCTP into DNA. This nucleoside analogue has shown potential for use as an activator in phosphoramidite chemistry and as a deoxyribonucleoside in oligonucleotide synthesis.</p>Fórmula:C11H13IN4O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:360.15 g/molN6-Benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution
CAS:<p>N6-Benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an analog of adenosine triphosphate (ATP). It is used in the study of protein kinase C. ATP and its analogs are able to phosphorylate proteins and regulate their activity. This study has shown that N6-benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an atp analog that activates protein kinase C, leading to the phosphorylation of proteins. This analog also inhibits tyrosine kinases, which may be due to its ability to inhibit the reuptake of serotonin and other transmitters.</p>Fórmula:C17H22N5O13P3·xNaPureza:Min. 95%Cor e Forma:Colorless PowderPeso molecular:597.3 g/mol3′-Guanylic acid disodium
CAS:<p>3′-Guanylic acid disodium is a nucleoside analog that inhibits viral replication and tumor growth. It is an antiviral agent that is active against herpes simplex virus type 1 and type 2, as well as cytomegalovirus. 3′-Guanylic acid disodium is also an anticancer agent that has shown promising results in animal models of glioma, lymphoma, lung cancer, and breast cancer. The molecule inhibits the synthesis of DNA by competitively inhibiting the action of ribonucleotide reductase. 3′-Guanylic acid disodium also inhibits protein synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. This drug has been shown to have a high purity and quality with no detectable impurities or contaminants.</p>Fórmula:C10H14N5O8P•Na2Pureza:Min. 95%Peso molecular:409.2 g/molent-abacavir
CAS:<p>Ent-abacavir is a drug that belongs to the group of antiretroviral drugs. It has minimal toxicity and has been shown to be effective in long-term treatment of HIV/AIDS. Ent-abacavir is also used as part of active antiretroviral therapy, which includes at least three or four different drugs. It inhibits the activity of reverse transcriptase, an enzyme involved in the replication process of HIV and other retroviruses. This drug has been shown to have few drug interactions with other medications, although caution should be taken when using ent-abacavir with drugs that are metabolized by cytochrome P450 enzymes. Ent-abacavir is not recommended for use in patients who have chronic viral hepatitis or who have a body mass index greater than 30 kg/m2 because its pharmacokinetic properties may be altered in these individuals.</p>Fórmula:C14H18N6OPureza:Min. 95%Peso molecular:286.33 g/molGuanosine 5'-diphosphate sodium
CAS:<p>Pyruvate kinase substrate</p>Fórmula:C10H15N5O11P2•Na2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:466.19 g/molAdenylyl-3'-5'-guanosine sodium salt
CAS:<p>3'-Adenylyl-5'-guanosine ammonium salt is a dinucleoside that competes with guanosine for binding to the enzyme adenylate cyclase. This reaction leads to increased levels of cyclic AMP, which causes an increase in the rate of viral replication. 3'-Adenylyl-5'-guanosine ammonium salt has been shown to inhibit the growth of pyogenic bacteria such as Streptococcus pyogenes and has also been used to treat influenza infections. 3'-Adenylyl-5'-guanosine ammonium salt is an inorganic compound that is found in tobacco. It can be synthesized from uridine and p-nitrophenyl phosphate by the reaction: 3'--O--(CH2)4--COOH + H2N--PO4--> 3'--O--(CH2)4--CONH2 + H3PO4</p>Fórmula:C20H24N10O11P·NaPureza:Min. 95%Peso molecular:634.43 g/mol3-Acetylpyridine adenine dinucleotide disodium, reduced form
CAS:<p>Reduced synthetic analog of NADH with an acetylpyridine modification. It is used as a reducing substrate to study the mechanisms of NAD(P)+-dependent reductases and to probe the active sites and catalytic processes of these important enzymes through its altered spectroscopic and binding properties. The disodium salt ensures good solubility for biochemical applications.</p>Fórmula:C22H30N6O14P2•Na2Pureza:Min. 95%Cor e Forma:Slightly Yellow PowderPeso molecular:710.43 g/mol6-Methyluridine
CAS:<p>Methyluridine is a derivative of uridine that is used in the synthesis of pyrimidine nucleotides. This drug is also an inhibitor of orotidine 5′-monophosphate decarboxylase, which converts orotic acid to uracil. The conformational properties of methyluridine have been studied and found to be similar to those of other purine derivatives, such as adenine and guanine. In addition, methyluridine has been shown to inhibit the growth of typhimurium and increase the production of uracil in human lymphocytes. Methyluridine is metabolized by hydroxylation in liver microsomes, yielding 6-carboxylic acid.</p>Fórmula:C10H14N2O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:258.23 g/mol2'-Deoxy-4'-ethynyl-2-fluoroadenosine
CAS:<p>2'-Deoxy-4'-ethynyl-2-fluoroadenosine (EFdA) is an analog of adenosine. EFdA is a potent inhibitor of HIV replication, and has been shown to be effective against other viruses such as influenza virus, herpes simplex virus, and vesicular stomatitis virus. EFdA was the first nucleoside analog to show antiviral activity in tissue culture against these viruses. This drug also inhibits the synthesis of mitochondrial rRNA and reduces the formation of mitochondrial DNA in human cells by inhibiting mitochondrial DNA polymerase γ. EFdA also prevents the binding of monoclonal antibodies to human B lymphocytes, which may be due to its steric interactions with plasma RNA. This drug is metabolized by cytochrome P450 2C8 and 2C9 into a variety of metabolites that are excreted in urine as glucuronides or sulfates. EFdA has a long</p>Fórmula:C12H12FN5O3Pureza:Min. 95%Peso molecular:293.25 g/mol5-Methoxyuridine-5'-triphosphate sodium, 100mM aqueous solution
CAS:<p>5-Methoxyuridine-5'-triphosphate is a monophosphate nucleoside that serves as a precursor for the synthesis of 5-methoxyuridine (5MU) and other nucleosides. It has antiviral effects, and is used in the treatment of herpes zoster infection. 5-Methoxyuridine-5'-triphosphate is an analog of uridine and deoxyribonucleosides with antiviral activity, which can be used to treat herpes zoster infection. This drug also has anticancer properties, which may be due to its ability to inhibit DNA synthesis by inhibiting ribonucleotide reductase and DNA polymerase, leading to cell death.</p>Fórmula:C10H17N2O16P3•NaxPureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:514.17 g/molUridine diphosphate choline (UDPC) sodium
CAS:<p>Uridine diphosphate choline (UDPC) sodium is a nucleotide that is used as a phosphoramidite for DNA synthesis. The chemical formula for UDPC is C8H14N4O8P. The activation of the molecule occurs in acidic conditions, which may be due to the formation of an amide bond between the terminal phosphate and the amino group on the phosphorylcholine. This same reaction can also occur in alkaline conditions. UDPC has been shown to inhibit viral replication, including HIV-1, by blocking reverse transcription of viral RNA into DNA. It also has anticancer effects, as it inhibits cell proliferation and induces apoptosis in cancer cells. UDPC does not have any known side effects or toxicity.</p>Fórmula:C14H25N3O12P2•NaPureza:Min. 95%Cor e Forma:PowderPeso molecular:512.3 g/molCiticoline sodium
CAS:<p>Citicoline is a complex organic molecule, a form of B-vitamin choline that acts as an intermediate in many biosynthetic pathways, for example, in the biosynthesis of cell membrane phospholipids. As a dietary supplement, citicoline is a source of choline and cytidine, two components that are quickly absorbed in the intestine and across the blood-brain barrier. The neuroprotective properties of citicoline improves mental performance increasing the levels of other brain-related chemicals like dopamine and norepinephrine, helping with recovery in stroke patients, reducing memory loss due to aging and improving vision in patients with glaucoma.</p>Fórmula:C14H26N4O11P2•NaPureza:Min. 98.0 Area-%Cor e Forma:White To Off-White SolidPeso molecular:511.31 g/mol7-Deaza-2'-C-ethynyladenosine
CAS:<p>7-Deaza-2'-C-ethynyladenosine (7DAA) is a research inhibitor that is classified as a polymerase inhibitor. It binds to the active site of the viral NS5B polymerase and inhibits RNA synthesis, which leads to virus replication. 7DAA has shown activity against hepatitis B virus (HBV) and hepatitis C virus (HCV). It also shows multifunctional properties in its inhibition of HBV genotypes A1, A3, and D1. In addition, 7DAA interacts with the RNA binding site on HCV polymerase protein and prevents binding of the viral RNA genome to this site. 7DAA also inhibits HIV replication by preventing assembly of the reverse transcriptase enzyme complex at an early stage.</p>Fórmula:C13H14N4O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:290.27 g/molAdenosine 2',3'-cyclic monophosphate
CAS:<p>Adenosine 2',3'-cyclic monophosphate triethylammonium salt (AMP-TEA) is a structural analogue of adenosine. It is a potent inhibitor of protein synthesis by preventing the phosphodiesterase activity of cyclic nucleotide phosphodiesterases and cyclic nucleotide phosphodiesterase. AMP-TEA can be used as a tool to study translation in tissue culture, as well as to examine the effects on protein synthesis and other biochemical reactions that are regulated by cyclic nucleotides. It is also used for the preparation of tissue samples for enzymatic analysis or for radiolabeling experiments.<br>AMP-TEA has an optimum pH of 4.5, but can be used at lower or higher pH values. The optimal temperature range for use is between 0°C and 50°C, with the maximum stability occurring at 37°C.</p>Fórmula:C10H12N5O6PPureza:Min. 95%Cor e Forma:PowderPeso molecular:329.21 g/mol
