Nucleotídeos
Subcategorias de "Nucleotídeos"
Foram encontrados 2637 produtos de "Nucleotídeos"
5-Methyl-2′-O-[2-(methylamino)-2-oxoethyl]-cytidine
5-Methyl-2′-O-[2-(methylamino)-2-oxoethyl]-cytidine is a nucleoside that is synthesized by phosphoramidite chemistry. It is a novel chemical compound with antiviral, anticancer, and deoxyribonucleoside properties. This nucleoside is modified in the 5′ position with a methyl group and has been shown to have cytotoxic effects on cancer cells.Fórmula:C13H20N4O6Pureza:Min. 95%Peso molecular:328.33 g/mol2',3',5'-Tri-O-acetylguanosine
CAS:2',3',5'-Tri-O-acetylguanosine is a protected form of the nucleoside guanosine which has potential application as a synthetic intermediate in nucleic acid and nucleoside chemistry.Fórmula:C16H19N5O8Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:409.35 g/molN2-Isobutyryl-9-(b-D-arabinofuranosyl)guanine
N2-Isobutyryl-9-(b-D-arabinofuranosyl)guanine is a monophosphate analog of guanine. It is a novel antiviral agent that inhibits the DNA polymerase and RNA polymerase activities of human immunodeficiency virus (HIV). The drug has a high purity and is available in large quantities.
Fórmula:C14H19N5O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:353.33 g/mol9-(b-D-Ribofuranosyl)isoguanine
CAS:9-(B-D-Ribofuranosyl)isoguanine is a purine analogue that is an anti-cancer drug. It has low potency and its biological properties are unknown. It has been shown to be an inhibitor of the polymerase chain reaction in vitro, but it is unclear if this activity will translate to in vivo models. 9-(B-D-Ribofuranosyl)isoguanine is structurally similar to pyrazole, which also inhibits the polymerase chain reaction in vitro. A recent study found that 9-(B-D-Ribofuranosyl)isoguanine may act as a toll-like receptor agonist and suppress lipopolysaccharide (LPS)-induced inflammation in mice, which suggests that this drug may have anti-inflammatory properties.
Fórmula:C10H13N5O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:283.25 g/mol5'-Carboxy-2',3'-O-isopropylideneadenosine
CAS:5'-Carboxy-2',3'-O-isopropylideneadenosine is a novel deoxyribonucleoside. It has high purity and high quality, good stability, and a low price. This product can be used as the raw material for synthesis of DNA, RNA, and phosphoramidites. It is an anticancer drug and antiviral agent that can be used to synthesize new drugs. It also has strong anti-inflammatory properties.Fórmula:C13H15N5O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:321.3 g/molPseudouridine-5'-triphosphate trisodium salt - 100mM aqueous solution
CAS:Pseudouridine-5'-triphosphate trisodium salt (PUR) is a nucleoside analogue that inhibits the synthesis of RNA. PUR is also a potent inhibitor of DNA synthesis and can be used to inhibit angiogenesis. PUR has been shown to have an effect on vascular endothelial cells, platelets, and cancer cells in vitro. This drug targets the vessels and other target cells such as those found in cardiovascular diseases, ovary, and cancer. PUR has been shown to be effective in vivo studies using mice models for the treatment of osteogenic sarcoma.Fórmula:C9H12N2O15P3Na3Pureza:Min. 95 Area-%Cor e Forma:Colorless PowderPeso molecular:550.09 g/molPseudouridine 5'-monophosphate disodium
CAS:Pseudouridine monophosphate disodium is an intermediate in the synthesis of uridylate, a nucleotide that is important for RNA and DNA synthesis. It is synthesized by the enzyme synthetase, which uses ATP as a phosphate donor. The enzyme has been found in rat liver microsomes and cell nuclei. Pseudouridine 5'-monophosphate disodium has an activity index of 2-3 and can be used to prepare samples for analysis by spectroscopy or chromatography. In addition, it has been shown to have biological properties such as anti-inflammatory activities and disease activity against inflammatory bowel diseases (IBD).
Fórmula:C9H13N2O9P•Na2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:370.18 g/mol2-Deoxycytidine 3',5'-diphosphate sodium salt
CAS:Please enquire for more information about 2-Deoxycytidine 3',5'-diphosphate sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C9H15N3O10P2•xNaPureza:Min. 95%Cor e Forma:PowderPeso molecular:479.14 g/molN1,O2'-Dimethyladenosine
CAS:N1,O2'-Dimethyladenosine is a monophosphate that is an antiviral agent. It has been shown to be a potent activator of the tRNA synthetase enzyme and also inhibits viral DNA synthesis. This drug is synthesized from diphosphate and phosphoramidites. N1,O2'-Dimethyladenosine has been shown to be highly active against viruses such as HIV-1, HIV-2, and HCV. It is also used in the production of modified nucleosides for use in synthetic constructs with therapeutic applications.
Fórmula:C12H17N5O4Pureza:(%) Min. 95%Cor e Forma:PowderPeso molecular:295.29 g/mol5'-Chloro-5'-deoxyadenosine
CAS:Adenosine analog
Fórmula:C10H12ClN5O3Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:285.69 g/molN3-Methyluridine
CAS:N3-Methyluridine is a monosodium salt of N3-methyluridine, which is an analogue of uridine. It is a nucleoside that is used as a precursor for RNA synthesis. In the body, N3-methyluridine is converted to uridine and then phosphorylated to form UMP. The phosphate group on UMP can be hydrolyzed by the enzyme kinase in order to produce ATP. N3-Methyluridine has been shown to be a potential biomarker for metabolic disorders and drug interactions with drugs such as loperamide, which inhibit mitochondrial function by inhibiting the enzyme p2y receptors.Fórmula:C10H14N2O6Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:258.23 g/mol1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)cytosine HCl
CAS:1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)cytosine HCl is a nucleoside analog for research applications. It contains a β-D-arabinofuranose sugar and a fluorine (F) at the 2'-position increases resistance to enzymatic degradation and alters its biological activity. The presence of the cytosine nucleobase allows it to mimic natural cytidine and be incorporated into DNA and the HCl salt form improves solubility and stability.Fórmula:C9H12FN3O4·HClPureza:Min. 95%Cor e Forma:PowderPeso molecular:281.67 g/molCytidine 5'-diphosphate ethanolamine disodium
CAS:Cytidine 5'-diphosphate ethanolamine disodium salt (CDP-ethanolamine) is a nucleotide that is synthesized in the cytosol. It is a precursor for the synthesis of phosphatidylethanolamines, which are important components of cell membranes. CDP-ethanolamine has been shown to be an inhibitor of enzymes, such as diacylglycerol acyltransferase and acetyl-CoA carboxylase. This inhibition leads to lower cellular levels of diacylglycerols and fatty acids, which may be beneficial for metabolic disorders such as hepatic steatosis and bowel disease.Fórmula:C11H18Na2N4O11P2Pureza:Min. 95 Area-%Cor e Forma:White To Off-White SolidPeso molecular:490.21 g/mol5-Methyl-2′-O-[2-(methylamino)-2-oxoethyl]uridine
CAS:5-Methyl-2′-O-[2-(methylamino)-2-oxoethyl]uridine (5MeUrd) is a diphosphate nucleoside that has been modified with a methyl group on the 2′ position. It is a novel, high quality, synthetic nucleoside with antiviral and anticancer properties. 5MeUrd is structurally similar to uridine and cytidine, which are deoxyribonucleosides. The phosphoramidite of 5MeUrd can be used for the synthesis of DNA, RNA, or monophosphate nucleosides in vitro. 5MeUrd has been shown to inhibit human leukemia cells and cancer cell lines in vitro by inhibiting DNA synthesis.Fórmula:C13H19N3O7Pureza:Min. 95%Peso molecular:329.31 g/molPyrimidine-4-carboxylic acid methyl ester
CAS:The pyrimidine-4-carboxylic acid methyl ester is a neutralized derivative of the natural amino acid pyrimidine-4-carboxylic acid. It can be metabolized in vivo to the active form, bleomycin. The neutralized form is useful for the synthesis of betaines and other compounds. This product is also used as an intermediate in the synthesis of metastable carbenes that are difficult to synthesize by other means. Pyrimidine-4-carboxylic acid methyl ester has been used as a reagent in mass spectrometry to identify isotopomers and isomers. It can also be used as a precursor for chemical transfer reactions with carbenes.Fórmula:C6H6N2O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:138.12 g/mol5-Methylcytidine-5'-monophosphate
CAS:5-Methylcytidine-5'-monophosphate is a nucleotide that is an intermediate in the synthesis of DNA. It is a neutral form and has been sequenced. 5-Methylcytidine-5'-monophosphate is found in cellular components, such as mitochondria and nuclei. The biochemical properties of this molecule are dependent on its methylation state. This molecule also plays a role in mitochondrial functions and nuclear DNA modifications.
Fórmula:C10H16N3O8PPureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:337.22 g/molUridine 5'-monophosphate
CAS:Uridine 5'-monophosphate (UMP) is a nucleotide that is synthesized from uridine. Uridine 5'-monophosphate has been shown to have anticancer activity in vitro and in vivo, as well as antiviral activity against herpes viruses. UMP has been shown to inhibit the protein synthesis of cells by inhibiting the enzyme activities of DNA polymerase and RNA polymerase. It also inhibits the synthesis of p2y receptors, which are involved in cell proliferation and differentiation. Further studies suggest that UMP may be an effective anti-inflammatory agent due to its ability to decrease prostaglandin production.Fórmula:C9H13N2O9PPureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:324.18 g/mol4-Demethylwyosine
CAS:4-Demethylwyosine is a metabolite found in the bacterium Pyrococcus furiosus. It is an intermediate in the biosynthesis of 2-amino-3,5-dimethyoxybenzoic acid. 4-Demethylwyosine has been shown to inhibit cancer cell proliferation by inhibiting the synthesis of lysine residues and base formation. This inhibition may be due to its methyl transferase activity, which leads to decreased levels of methionine, or it may be due to its ability to act as a carboxylate group donor. 4-Demethylwyosine has also been shown to bind with DNA and RNA, regulating posttranscriptional processes such as protein translation and transcription.Fórmula:C13H15N5O5Pureza:Min. 80 Area-%Cor e Forma:PowderPeso molecular:321.29 g/mol2',3'-O-Isopropylideneguanosine
CAS:2',3'-O-Isopropylideneguanosine is a nucleoside for use in research applicationsFórmula:C13H17N5O5Pureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:323.31 g/mol8-Hydroxyadenosine
CAS:8-Hydroxyadenosine (8-OHdG) is a purine nucleoside that is formed as a result of oxidative DNA damage. It is not an essential metabolite because it can be synthesized de novo. 8-OHdG has been shown to have potent anti-tumor activity in vitro and in vivo, which may be due to its ability to inhibit DNA replication. The biological effects of 8-OHdG are attributed to its ability to form hydrogen bonds with guanine residues in the double helix, and electrochemical detectors have been developed for its detection.Fórmula:C10H13N5O5Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:283.25 g/mol
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