Nucleotídeos
Os nucleotídeos são compostos orgânicos que servem como building blocks dos ácidos nucleicos, essenciais para a formação de DNA e RNA. Cada nucleotídeo é composto por uma base nitrogenada, uma molécula de açúcar e um ou mais grupos fosfato. Esses nucleotídeos se unem para formar longas cadeias, criando o material genético que carrega e transmite informações genéticas em todos os organismos vivos. Nesta seção, você encontrará uma ampla variedade de nucleotídeos cruciais para pesquisas em genética, biologia molecular e bioquímica. Eles são fundamentais para estudar processos genéticos, sintetizar ácidos nucleicos e desenvolver ferramentas diagnósticas e terapêuticas. Na CymitQuimica, oferecemos nucleotídeos de alta qualidade para apoiar suas pesquisas científicas e aplicações, garantindo precisão e confiabilidade em seus experimentos.
Subcategorias de "Nucleotídeos"
Foram encontrados 2634 produtos de "Nucleotídeos"
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8-Hydroxyadenosine
CAS:<p>8-Hydroxyadenosine (8-OHdG) is a purine nucleoside that is formed as a result of oxidative DNA damage. It is not an essential metabolite because it can be synthesized de novo. 8-OHdG has been shown to have potent anti-tumor activity in vitro and in vivo, which may be due to its ability to inhibit DNA replication. The biological effects of 8-OHdG are attributed to its ability to form hydrogen bonds with guanine residues in the double helix, and electrochemical detectors have been developed for its detection.</p>Fórmula:C10H13N5O5Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:283.25 g/mol2'-O-Methylcytidine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS:<p>2'-O-Methylcytidine-5'-triphosphate sodium salt is a synthetic, modified nucleoside analog. It can be used as an antiviral agent and anticancer drug to inhibit viral replication and tumor growth. 2'-O-Methylcytidine-5'-triphosphate sodium salt has the ability to activate cellular DNA synthesis. This compound also inhibits RNA polymerase activity in cancer cells, which inhibits the production of proteins vital for cell division. 2'-O-Methylcytidine-5'-triphosphate sodium salt can be used as a phosphoramidite building block for the synthesis of oligonucleotides with novel structures.</p>Fórmula:C10H18N3O14P3·xNaPureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:497.18 g/molPoly(2'-O-Methyladenosine 5'-monophosphate) sodium
CAS:<p>Please enquire for more information about Poly(2'-O-Methyladenosine 5'-monophosphate) sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:(C11H16N5O7P)x•NaxPureza:Min. 95%Triciribine
CAS:<p>Protein kinase B inhibitor;</p>Fórmula:C13H16N6O4Pureza:Min. 95%Cor e Forma:White/Off-White SolidPeso molecular:320.3 g/mol2',3'-Anhydroadenosine
CAS:<p>2',3'-Anhydroadenosine is a nucleoside for a range of applications</p>Fórmula:C10H12N2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:240.21 g/mol1'-13CUridine
CAS:<p>1'-13CUridine is a nucleoside analog attached to an isotope</p>Fórmula:CC8H12N2O6Cor e Forma:PowderPeso molecular:245.19 g/molN1-Methyladenosine-5’-monophosphate
CAS:<p>The N1-methyladenosine is a reversible modification in tRNA, mRNA and long non-coding RNA</p>Fórmula:C11H16N5O7PPureza:Min. 95%Cor e Forma:PowderPeso molecular:361.25 g/molKinetin riboside
CAS:Kinetin is a plant hormone that regulates cell proliferation and differentiation. Kinetin riboside is a derivative of kinetin in which the ribose moiety has been converted to ribosyl-ribitol. Kinetin riboside has shown the ability to inhibit cancer cells by inducing apoptosis, which may be related to its ability to inhibit cyclin D2 and mitochondrial membrane potential. In addition, kinetin riboside has been shown to protect against oxidative stress and decrease mitochondrial function in cells. This compound may have therapeutic potential for cancer treatment and other diseases caused by oxidative stress or mitochondrial dysfunction.Fórmula:C15H17N5O5Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:347.33 g/molCapecitabine
CAS:<p>Pro-drug of 5-FU; anti-cancer agent</p>Fórmula:C15H22FN3O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:359.35 g/molN-Cbz gemcitabine
CAS:N-Cbz gemcitabine is a novel nucleoside analog that is chemically modified to be activated by enzymes in the cell. It has been shown to have high purity and high quality. In addition, N-Cbz gemcitabine is an anticancer drug that is most effective against cells with a low number of nucleotides per cell. This drug has shown antiviral properties and is used for the treatment of HIV/AIDS patients.Fórmula:C17H17F2N3O6Pureza:Min. 95%Cor e Forma:Off-White To Yellow SolidPeso molecular:397.33 g/mol2-Thiocytidine
CAS:<p>2-Thiocytidine is a nucleoside that is an intermediate in the synthesis of thiamine. It has been shown to be effective in the treatment of prostate cancer cells, which may be due to its ability to inhibit protein synthesis. 2-Thiocytidine binds to the catalytic site of ribonucleotide reductase (RR) and inhibits the enzyme's activity, thereby inhibiting DNA synthesis. This drug also has been shown to inhibit crosslinking caused by UV light or other agents that generate reactive oxygen species. 2-Thiocytidine binds to the active site of RR and prevents the formation of the enzyme-substrate complex. This binding prevents reduction of ribose into ribonucleotides and inhibits DNA synthesis.</p>Fórmula:C9H13N3O4SPureza:Min. 95%Cor e Forma:Yellow PowderPeso molecular:259.28 g/molN6-Etheno 2'-deoxyadenosine
CAS:<p>N6-Etheno 2'-deoxyadenosine is a nucleoside analogue that inhibits DNA synthesis by binding to the enzyme thymidylate synthase, which catalyzes the conversion of deoxyuridine monophosphate to thymidine monophosphate. This drug has been shown to be genotoxic in vitro and in vivo, as evidenced by its ability to induce chromosomal aberrations in cultured human lymphocytes and disrupt DNA replication in mammalian cells. It also reacts with mismatched base pairs and dna duplexes, leading to their degradation. N6-Etheno 2'-deoxyadenosine binds reversibly to antibodies and can be detected using an analytical method that employs monoclonal antibodies.</p>Fórmula:C12H13N5O3Cor e Forma:White Off-White PowderPeso molecular:275.26 g/mol3',5'-Di-O-acetyl-2'-deoxy-5-iodouridine
CAS:<p>3',5'-Di-O-acetyl-2'-deoxy-5-iodouridine is an inorganic, deoxyribonucleoside. It is the acetyl derivative of 2'-deoxy-5-iodouridine, which is an analog of uracil. 3',5'-Di-O-acetyl-2'-deoxy-5-iodouridine has been shown to have antiviral properties against herpes simplex virus type 1 (HSV1) and herpes simplex virus type 2 (HSV2) in animals. This drug also has antiangiogenic properties, inhibiting the growth of new blood vessels and tissues at the site of a tumour. Studies have shown that 3',5'-di-O acetyl 2'-deoxyuridine can be incorporated into exudates from human cancer patients and can inhibit tumor cell proliferation in vivo.</p>Fórmula:C13H15IN2O7Pureza:Min. 95%Peso molecular:438.18 g/mol2′-O-(2-Methoxy-2-oxoethyl)-5-methyl-uridine
CAS:<p>2′-O-(2-Methoxy-2-oxoethyl)-5-methyl-uridine is a nucleoside that can be used as an anticancer drug and antiviral agent. It has shown potent in vitro cytotoxic activity against human leukemia cells and other cancer cell lines, including breast, prostate, ovarian, and colon cancers. 2′-O-(2-Methoxy-2-oxoethyl)-5-methyl-uridine also has good antiherpetic potential. This compound is a novel and synthetic nucleoside with high purity, high quality, and excellent stability. It is soluble in water, methanol, ethanol, acetone, acetonitrile; slightly soluble in chloroform; insoluble in ether or hexane. CAS No. 149301-23-5</p>Fórmula:C13H18N2O8Pureza:Min. 95%Peso molecular:330.29 g/mol5-Chloro-2',3'-dideoxy-3'-fluorouridine
CAS:<p>5-Chloro-2',3'-dideoxy-3'-fluorouridine is a nucleoside analog that inhibits the replication of HIV by competing with other nucleosides for incorporation into viral DNA, thereby inhibiting the production of new viruses. This drug has been shown to have an inhibitory effect on the replication of HIV and has been approved as an antiretroviral agent. 5-Chloro-2',3'-dideoxy-3'-fluorouridine is active against most HIV strains and is able to suppress viral load in patients with chronic hepatitis B or C. It also inhibits the hepatic metabolism of drugs metabolized by cytochrome P450 enzymes, such as CYP3A4 inducers. The effective dose for this drug ranges from 100 mg to 200 mg per day.</p>Fórmula:C9H10ClFN2O4Pureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:264.64 g/mol2-Amino-6-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
CAS:2-Amino-6-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a protected nucleoside analog.In this compound the sugar’s hydroxyl groups are acetylated to make it chemically stable and reactive in nucleoside chemistry.Pureza:Min. 95%2′-O-[2-(Methylamino)-2-oxoethyl]adenosine
CAS:<p>2′-O-[2-(Methylamino)-2-oxoethyl]adenosine is a nucleoside that can be used as an anticancer, antiviral, and anticoagulant. It is synthesized from the natural nucleosides adenosine and cytidine. 2′-O-[2-(Methylamino)-2-oxoethyl]adenosine has been shown to inhibit the growth of tumor cells in vitro. This compound also inhibits viral replication by inhibiting DNA synthesis through inhibition of ribonucleotide reductase and deoxyribonucleotide reductase. 2′-O-[2-(Methylamino)-2-oxoethyl]adenosine is phosphorylated by ATP to produce 2′-O-[2-(methylamino)-2-oxoethyl]adenosinophosphate (AMP). AMP then binds to the purinergic receptor P1, which leads to</p>Fórmula:C13H18N6O5Pureza:Min. 95%Peso molecular:338.32 g/mol1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)-5-iodouracil
1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)-5-iodouracil is a modified nucleoside analog for research applications. It contains a uracil base with an iodine atom, a fluorinated sugar that produces increased metabolic stability and benzoyl-protecting groups at the 3'- and 5'-hydroxyl positions, commonly used in nucleoside synthesis.Pureza:Min. 95%N6-Benzoyl-2'-O-methyladenosine
CAS:<p>N6-Benzoyl-2'-O-methyladenosine is a nucleoside that is chemically synthesized. It has been shown to be an inhibitor of the polyhedrosis virus, which causes an infectious disease in silkworms. N6-Benzoyl-2'-O-methyladenosine also inhibits viral replication by interfering with the synthesis of messenger RNA. This compound can be used as a silver nitrate or silver salt prodrug for treating diseases caused by viruses and bacteria. This drug is not active against DNA viruses because it does not possess phosphate groups on its structure.</p>Fórmula:C18H19N5O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:385.37 g/mol2'-Deoxy-2'-fluoroadenosine-5'-triphosphate tetralithium salt
CAS:<p>2'-Deoxy-2'-fluoroadenosine-5'-triphosphate tetralithium salt (FdATP) is a competitive inhibitor of ATP. It inhibits the synthesis of RNA, DNA, and protein in cell culture at high concentrations. FdATP is also an analog of adenosine triphosphate (ATP), which is needed for cellular energy production. The competitive inhibition of ATP by FdATP prevents the formation of a phosphorylated enzyme that is required for the initiation of DNA synthesis. This can lead to cell death, as the cells cannot produce proteins required for growth and replication.</p>Fórmula:C10H11FN5O12P3•Li4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:532.9 g/mol2'-Deoxyadenosine monohydrate
CAS:<p>2'-Deoxyadenosine monohydrate (2'-dA) is an adenosine nucleotide that is synthesized by the enzyme adenosine kinase. It is a competitive inhibitor of phosphodiesterase and inhibits the activity of this enzyme, which breaks down cyclic nucleotides to their corresponding monophosphate form. This leads to elevated levels of cAMP, which can cause neuronal death by apoptosis. 2'-dA has been shown to have sublethal effects on neurons at concentrations that are below those required for neuronal death and apoptosis. This may be due to its ability to inhibit the synthesis of ATP, thereby limiting the production of phosphoryl groups from ATP. The inhibition of ATP synthesis also reduces the amount of energy available for other processes within cells.</p>Fórmula:C10H13N5O3•H2OPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:269.26 g/mol5'-O-tert-Butyldiphenylsilyl-thymidine
CAS:<p>5'-O-tert-Butyldiphenylsilyl-thymidine (TBS-T) is a class of nucleoside that is synthesized by condensation of two molecules of 5'-O-tert-butyldiphenylsilyl-2',3'-dideoxyuridine (TBDPS) and N6-benzoyladenine. TBS-Ts are used in the synthesis of phosphorothioate oligodeoxynucleotides. They have been shown to be useful as activators for the formation of phosphite linkages at the 3' terminus of DNA oligonucleotides. TBS-T is also used in other applications, such as the preparation of diastereomerically pure nucleosides for use in chemical reactions.</p>Fórmula:C26H32O5N2SiPureza:Min. 95%Cor e Forma:White PowderPeso molecular:480.63 g/molThymidine 3′-monophosphate disodium
CAS:<p>Thymidine 3′-monophosphate disodium is a chemotherapeutic agent that has been shown to have antiviral and anticancer properties. It is a nucleoside analogue, which mimics the structure of thymidine and inhibits DNA synthesis by interfering with the DNA replication process. Thymidine 3′-monophosphate disodium is also used as an activator in the synthesis of deoxyribonucleosides and ribonucleosides. This product is synthetic, high quality, and not chemically modified. It has CAS number 68698-19-1 and molecular weight of 242.06 g/mol.</p>Fórmula:C10H15N2O8P•Na2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:368.19 g/mol5'-O-DMT-thymidine 3'-O-succinate triethylammonium salt
CAS:<p>5'-O-DMT-thymidine 3'-O-succinate triethylammonium salt is a novel antiviral agent that inhibits viral replication by competing with natural nucleosides for incorporation into the viral DNA or RNA. The 5'-O-DMT group prevents the elimination of thymidine from the monophosphate form. This product has a high purity and quality, as well as potent antiviral activity against HIV and other viruses.</p>Fórmula:C35H36N2O10·xC6H15NPureza:Min. 95%Cor e Forma:PowderPeso molecular:745.86 g/mol2-Methylthioadenosine
CAS:<p>2-Methylthioadenosine is a purine nucleoside which induces necrotic cell death. It is the first of its kind to be shown to have activity against squamous carcinoma cells, and is activated by nucleoside phosphorylase in order to produce its cytotoxic form. 2-Methylthioadenosine also inhibits the transcription-polymerase chain reaction and increases oxidative injury. This drug has been shown to have receptor activity in brain cells, as well as chemotactic activity for gland cells. 2-Methylthioadenosine has been used as a model organism for polymerase chain reactions, and has been shown to inhibit p2y receptors in the human colon cancer cell line HT29.</p>Fórmula:C11H15N5O4SPureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:313.34 g/mol5'-O-(4,4'-Dimethoxytrityl)adenosine
CAS:<p>5'-O-(4,4'-Dimethoxytrityl)adenosine is a phosphoramidite that can be used as an activator for the synthesis of DNA. It is also used in the preparation of modified nucleosides and has anticancer activity. 5'-O-(4,4'-Dimethoxytrityl)adenosine is a modified ribonucleoside with high quality and high purity. This product has been shown to have antiviral activity against HIV-1.</p>Fórmula:C31H31N5O6Pureza:Min. 95 Area-%Cor e Forma:White Off-White PowderPeso molecular:569.61 g/mol5'-Deoxy-5-fluorocytidine
CAS:<p>5'-Deoxy-5-fluorocytidine is a cytosolic nucleoside analogue that is phosphorylated by cellular enzymes to the active form 5'-deoxy-5-fluorouridine monophosphate. It is a prodrug, which is activated in the body to release 5-FU and inhibits the growth of cancer cells. 5'-Deoxy-5-fluorocytidine has been shown to be effective against metastatic colorectal cancer in humans and resistant breast cancer in mice. The drug can also be used as an oral prodrug for 5-FU, which has a wide therapeutic index and low toxicity. Studies have shown that it selectively inhibits proliferation of solid tumours through inhibition of protein synthesis and cell division. The drug also has antiangiogenic effects, which are thought to contribute to its antitumor activity.</p>Fórmula:C9H12FN3O4Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:245.21 g/mol2'-Deoxy-3,5-dimethylcytidine
CAS:<p>2'-Deoxy-3,5-dimethylcytidine is a nucleoside analog that is an activator of the ribonucleotide reductase enzyme. It has been shown to have anticancer properties in vitro and in vivo. 2'-Deoxy-3,5-dimethylcytidine has also been shown to be effective against HIV and herpes virus infections. 2'-Deoxy-3,5-dimethylcytidine is synthesized from deoxyribonucleosides or nucleosides by phosphitylation with phosphoramidites or diphosphates. The CAS number for this product is 198198-29-7.</p>Fórmula:C11H17N3O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:255.27 g/mol5'-O-DMT-2'-O-hexylphthalimidouridine
<p>5'-O-DMT-2'-O-hexylphthalimidouridine is a novel nucleoside analog with anticancer activity. It is a modified nucleoside that has been synthesized and purified in high purity. 5'-O-DMT-2'-O-hexylphthalimidouridine is an activator of DNA and RNA synthesis and has antiviral properties. It also inhibits the production of tumor necrosis factor alpha (TNFα) by human synovial cells. This compound binds to the RNA polymerase II enzyme, which prevents transcription of genetic material from DNA templates into messenger RNA. This leads to inhibition of protein synthesis and cell death by apoptosis.</p>Fórmula:C44H45N3O10Pureza:Min. 95%Peso molecular:775.86 g/mol2'-O-Methylcytidine
CAS:<p>2'-O-Methylcytidine is a nucleoside with a hydroxyl group on the 2' carbon. The hydroxyl group makes it an effective inhibitor of viral replication, and it has been shown to be active against HIV-1 in cell culture. 2'-O-Methylcytidine is also metabolized by nucleotide salvage pathways, and the metabolic response can be studied using proton nuclear magnetic resonance (NMR) spectroscopy and x-ray diffraction data. It has been found that 2'-O-Methylcytidine inhibits protein synthesis in cancer cells, and this may be due to its ability to bind to the response element on DNA.</p>Fórmula:C10H15N3O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:257.24 g/molβ-Nicotinamide adenine dinucleotide sodium dihydrate
CAS:<p>Coenzyme and regenerating electron donor in catabolic processes</p>Fórmula:C21H26N7NaO14P2•(H2O)2Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:721.44 g/mol4-Hydroxy-6-methylpyrimidine
CAS:<p>4-Hydroxy-6-methylpyrimidine (4-OHMP) is a metabolite of trimethyltin. It is formed in the liver by methylation of 4,6-dimethylpyrimidine (4,6-DMPU). The levels of 4-OHMP in urine samples are used to monitor exposure to this agent. The median values for urinary concentrations of 4-OHMP are typically 10 times higher than those found in blood samples. The metabolite can be detected in urine up to 2 weeks after an individual’s last contact with trimethyltin. This compound has been shown to inhibit the synthesis of glycol dimethyl ethers and carbamates.</p>Fórmula:C5H6N2OPureza:Min. 95%Peso molecular:110.11 g/molN2,N2,7-Trimethylguanosine
CAS:<p>Trimethylguanosine is a hydrogen-bonded base that is found in the DNA of all living organisms. It has a diagnostic role in cancer and metabolic disorders, as well as in the study of cell culture. Trimethylguanosine can be used to identify cancer cells by measuring its fluorescence properties, which are different from those of healthy cells. This compound also has a role in the diagnosis of metabolic disorders, such as diabetes mellitus and renal disease. Trimethylguanosine is also involved in biological function, and is necessary for the synthesis of proteins and nucleic acids.</p>Fórmula:C13H20N5O5Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:326.33 g/molL-Cytidine
CAS:<p>L-Cytidine is a nucleoside that is found in the body, and is also used as a drug. It is a precursor to other nucleosides, such as cytidine triphosphate, which is involved in DNA synthesis and repair. L-Cytidine has been shown to be effective against HIV infection by inhibiting the activity of the enzyme ns3 protease. This inhibition prevents viral proteins from being released from cells and infecting other cells. L-Cytidine has also been shown to be an inhibitor of creatine kinase and glycosidation, two enzymes that are necessary for cell metabolism. L-Cytidine has also been shown to be reactive with halides, which may lead to unwanted side effects.</p>Fórmula:C9H13N3O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:243.22 g/molN6-Benzoyl-2'-O-(2-methoxyethyl)adenosine
CAS:<p>N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine is a novel nucleoside that can be used as an antiviral agent. It is an activator of viral polymerase and inhibits the proliferation of cells infected with HIV. This compound has been synthesized from 2'-deoxyadenosine monophosphate, which is a precursor to RNA and DNA synthesis. N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine has also been shown to inhibit the growth of experimental tumors in mice. The synthesis of this compound is reliable and reproducible, making it a high quality product.</p>Fórmula:C20H23N5O6Pureza:Min. 95%Peso molecular:429.43 g/mol2'-Deoxy-5'-O-DMT-cytidine
CAS:<p>2'-Deoxy-5'-O-DMT-cytidine is an organic compound. It is a synthetic, combinational and amine nitrogen containing heterocyclic compound that is used in organic synthesis. This chemical is also used as a building block for the synthesis of heterocyclic compounds with other functional groups such as thionyl, formulae, chlorides and hydrogen atoms.</p>Fórmula:C30H31N3O6Pureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:529.58 g/mol1-(α-D-Ribofuranosyl)uracil
CAS:1-(α-D-Ribofuranosyl)uracil is a nucleoside analog made up of a uracil attached to a ribose sugar at the 1-position, with the sugar in the α configuration. This compound is of interest in biochemistry research and nucleoside chemistry, especially when studying stereochemistry or synthesizing analogs.Fórmula:C9H12N2O6Pureza:(¹H-Nmr) Min. 95 Area-%Cor e Forma:PowderPeso molecular:244.2 g/mol2',3'-Dideoxyinosine
CAS:<p>2',3'-Dideoxyinosine is a purine analog that can suppress human immunodeficiency virus (HIV) replication after intracellular metabolic conversion</p>Fórmula:C10H12N4O3Pureza:Min. 95 Area-%Cor e Forma:White Off-White PowderPeso molecular:236.23 g/molUridine 5'-monophosphate disodium salt
CAS:Uridine 5'-monophosphate disodium salt (UDP-MS) is a structural analog of uridine that is used as a dietary supplement. It has been shown to inhibit phosphodiesterases and cyclic nucleotide phosphodiesterases, which are enzymes that degrade the secondary messenger, cyclic adenosine monophosphate (cAMP). This inhibition leads to increased levels of cAMP in cells, which stimulates protein kinase A activity and promotes cellular differentiation. The analysis of UDP-MS has been performed using liquid chromatography with ultraviolet detection.Fórmula:C9H11N2Na2O9PPureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:368.15 g/mol2'-Deoxy-5-formylcytidine
CAS:<p>2'-Deoxy-5-formylcytidine is a nucleoside analog that is used as a chemotherapeutic agent. It is cytotoxic to cells by binding to DNA and preventing the synthesis of DNA, RNA, and protein. The drug has been shown to induce cellular senescence in human fibroblasts, which can be reversed by the addition of deuterium. 2'-Deoxy-5-formylcytidine also inhibits the production of reactive oxygen species (ROS) by inducing the expression of antioxidant enzymes such as superoxide dismutase 2 and glutathione peroxidase 1. The oxidation products are misincorporated into DNA strands, leading to intramolecular hydrogen bonds with cytosine bases. These modifications lead to denaturation of DNA and inhibition of transcription and replication.<br>2'-Deoxy-5-formylcytidine also interacts with oligodeoxynucleotides, which leads to misinc</p>Fórmula:C10H13N3O5Pureza:Min. 97 Area-%Cor e Forma:White PowderPeso molecular:255.23 g/mol7-Deaza-2'-deoxyxanthosine
CAS:<p>7-Deaza-2'-deoxyxanthosine is an oligodeoxynucleotide that is a substrate for the enzyme dUTPase. The allyl group on 7-deaza-2'-deoxyxanthosine is used to attach it to the 3' end of DNA, where it acts as a competitive inhibitor of RNA synthesis. The ethyl group at the end of the molecule is used to attach it to the 5' end of DNA, where it inhibits transcription and replication by binding with RNA polymerase. 7-Deaza-2'-deoxyxanthosine has been shown to be effective in preventing stenosis following coronary bypass surgery, as well as in treating heart disease by reducing levels of xanthosine.</p>Fórmula:C11H13N3O5Pureza:Min. 95%Cor e Forma:Beige PowderPeso molecular:267.24 g/molUridine 5'-diphosphate choline ammonium
CAS:<p>Uridine 5'-diphosphate choline ammonium salt is a chemical compound that contains two molecules of uridine and one molecule of choline. It is a hexamer with an empirical formula of C6H14N4O13P3. Uridine 5'-diphosphate choline ammonium salt can be found in plants and animals, as well as being synthesized by the human body. This compound is present in the interstitium, which are the spaces between cells, and may play a role in the nutritional status of humans.</p>Fórmula:C14H28N4O12P2Pureza:Min. 90 Area-%Cor e Forma:PowderPeso molecular:506.34 g/mol2'-Deoxy-2'-fluoroinosine
CAS:<p>2'-Deoxy-2'-fluoroinosine is a modified nucleoside analog derived from inosine, where the 2' hydroxyl group of the sugar (normally present in ribonucleosides) is replaced with a fluorine atom, and the molecule contains a deoxyribose sugar.</p>Fórmula:C10H11FN4O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:270.22 g/mol2,4,6-Trichloro-5-methylpyrimidine
CAS:<p>2,4,6-Trichloro-5-methylpyrimidine is a nucleoside for use in research applications</p>Fórmula:C5H3Cl3N2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:197.45 g/molThymidine-5'-diphosphate-L-rhamnose disodium
CAS:<p>Thymidine-5'-diphosphate-L-rhamnose disodium is a nucleoside that belongs to the class of modified nucleosides. It is a synthetic, modified thymidine with a phosphate group at the 5'-position and L-rhamnose at the 2' position. Thymidine-5'-diphosphate-L-rhamnose disodium has antiviral and anticancer activities, as well as high purity and high quality. This compound has been shown to inhibit HIV replication in vitro and in vivo. Thymidine-5'-diphosphate-L-rhamnose disodium is also used in the synthesis of DNA and RNA.</p>Fórmula:C16H24N2O15P2Na2Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:592.29 g/mol2'-Azido-2'-deoxyadenosine
CAS:<p>2'-Azido-2'-deoxyadenosine is a synthetic nucleoside analog of adenosine in which the 2'-hydroxyl group of the ribose sugar is replaced by an azido group (–N₃), and the 3'- and 5'-hydroxyl groups remain intact. This modification confers unique chemical properties, including the ability to participate in bioorthogonal "click" chemistry reactions, particularly azide-alkyne cycloadditions, making it useful for labeling and tracking nucleic acids in biochemical studies. Additionally, the azido substitution can influence enzymatic recognition and incorporation by polymerases, allowing its use in studying nucleic acid metabolism, drug design, and therapeutic nucleoside analog development.</p>Fórmula:C10H12N8O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:292.25 g/mol2'-C-Methyluridine
CAS:<p>2'-C-Methyluridine is a synthetic nucleoside analog derived from uridine, modified with a methyl group at the 2'-carbon of the ribose sugar. This small chemical change has important implications for RNA biology, antiviral drug development, and biochemical research, especially in targeting RNA viruses.</p>Fórmula:C10H14N2O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:258.23 g/mol5'-O-DMT-5-[N-(6-(trifluoroacetamido)hexyl)-3-E-acrylamido]-2'-deoxyuridine
CAS:5'-O-DMT-5-[N-(6-(trifluoroacetamido)hexyl)-3-E-acrylamido]-2'-deoxyuridine is a novel phosphoramidate nucleoside monophosphate, which is a phosphate analog of 2'-deoxyuridine. It has been shown to be an activator for DNA polymerases and is able to inhibit the replication of DNA in vitro. It also has antiviral properties, as it inhibits the synthesis of viral RNA. 5'-O-DMT-5-[N-(6-(trifluoroacetamido)hexyl)-3-E-acrylamido]-2'-deoxyuridine also has anti-inflammatory effects, as it inhibits prostaglandin synthesis.Fórmula:C41H45F3N4O9Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:794.83 g/mol3'-O-Methylcytidine
CAS:<p>3'-O-Methylcytidine is an acidic guanine nucleoside that is a component of RNA. It is a biochemical building block and a co-substrate in the synthesis of DNA and RNA. 3'-O-Methylcytidine has been shown to be hydroxylated by the enzyme cytidine 5'-monophosphate, which leads to its termination when it reaches the ribosome. This nucleoside also inhibits bacterial growth through inhibition of ribosomal function, leading to reduced protein synthesis. 3'-O-Methylcytidine can act as an environmental pollutant, especially in chloride environments such as seawater. It has been found to be globally distributed in dinucleotides and monomethylated forms, with biosynthetic pathways similar to other nucleic acids.</p>Fórmula:C10H15N3O5Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:257.24 g/molADP monosodium salt - Bio-X ™
CAS:<p>Adenosine 5'-diphosphate monosodium salt (ADP) is an adenine nucleotide which is phosphorylated into ATP by the enzyme ATPase. This phosphorylation is essential in cellular homeostasis due to its role in energy storage and nucleic acid metabolism.</p>Fórmula:C10H15N5O10P2•NaPureza:Min. 95%Cor e Forma:PowderPeso molecular:449.18 g/mol
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