
Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3567 produtos de "Nucleosídeos"
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6-Dimethylamino-9-(b-D-ribofuranosyl)purine
CAS:<p>6-Dimethylamino-9-(b-D-ribofuranosyl)purine (6-DMAP) is an analog of adenine that has been shown to have anticancer activity in human serum and tissue culture. 6-DMAP can inhibit the synthesis of ATP, leading to cell death by significantly inhibiting cellular processes such as glycolysis and DNA replication. 6-DMAP also has a significant cytotoxicity on various types of cancer cells and plant tissues. The mechanism of action for the anticancer activity of 6-DMAP is not yet known, but it may be due to its ability to interfere with purine metabolism or its ability to form covalent bonds with DNA.</p>Fórmula:C12H17N5O4Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:295.3 g/mol5-Hydroxycytidine
CAS:<p>5-Hydroxycytidine is a pyrimidine nucleoside that is found in DNA and RNA. It can be produced by the conversion of cytidine 5-monophosphate to cytidine 5'-diphosphate, which is then hydrolyzed to produce 5-hydroxycytidine. This conversion requires the enzyme cytidylate kinase. The structure of 5-hydroxycytidine differs from other pyrimidine nucleosides as its hydroxyl group does not have an acidic proton present. Biological functions that have been attributed to 5-hydroxydihydrocytidylic acid include its ability to inhibit translation and induce cell death in lung cells. This compound has also been shown to modify DNA duplexes and form bioconjugates with proteins or small molecules, such as fluorescein and digoxigenin. These modifications are used in analytical methods such as phase chromatography, nuclear magnetic resonance spectroscopy</p>Fórmula:C9H13N3O6Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:259.22 g/mol5'-O-Trityl-D3-thymidine
Produto Controlado<p>5'-O-Trityl-D3-thymidine is a modified nucleoside that contains the natural nucleobase thymine and a radioactive isotope tritium (H3). It is used as a precursor in the preparation of DNA. 5'-O-Trityl-D3-thymidine is a ribonucleoside, which can be converted to deoxyribonucleosides by removal of the 5'-O-trityl group. The synthesis of DNA from 5'-O-trityl-D3-thymidine is accomplished by phosphoramidite chemistry.<br> 5'-O-Trityl-D3-thymidine has antiviral properties, demonstrated by its ability to inhibit viral DNA replication in vitro.</p>Fórmula:C29H25N2O5D3Pureza:Min. 95%Peso molecular:487.56 g/mol2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine
CAS:<p>2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine is a modified nucleoside that has antiviral, anticancer and antimalarial activities. This compound has been synthesized as a monophosphate derivative of the natural nucleoside uridine. It is an activator of DNA polymerase, which helps to synthesize DNA in cells. 2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine also has anticancer activity due to its ability to inhibit the replication of the human tumor virus KSHV.</p>Pureza:Min. 95%5-(Azidomethyl)-2’-deoxyuridine
CAS:<p>5-azidomethyl-2-deoxyuridine (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similarly to EdU (NE08701). Unlike EdU that needs to be further modified with azides in the presence of copper catalyst, AmdU can also react in the absence of copper catalyst using spAAC Click Chemistry with strained cycloalkynes, such as cyclooctynes. This enables detection of nascent DNA in benign, copper free conditions.</p>Fórmula:C10H13N5O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:283.24 g/molN6-Benzoyl-5'-O-2'-deoxyadenosine
<p>N6-Benzoyl-5'-O-2'-deoxyadenosine is a modified nucleoside that contains a benzoyl group. This nucleoside has been shown to be an antiviral and anticancer agent, and is also active against herpes simplex virus type 1 (HSV1). N6-Benzoyl-5'-O-2'-deoxyadenosine may be a potential therapeutic for the treatment of HSV1 infection. It is also believed to have anti-inflammatory properties. The synthesis of this compound can be achieved by reacting 5'-O-tetraisopropyldiphenylphosphoramidite with benzoyl chloride in the presence of triethylamine.</p>Fórmula:C36H31N5O4Pureza:Min. 95%Peso molecular:597.66 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine
CAS:<p>4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine (4FA) is a potent inhibitor of the growth of HIV. It has been shown to inhibit the production of inflammatory cytokines and chemokines, which are associated with inflammatory diseases such as arthritis and asthma. 4FA has also been shown to inhibit glycogen synthase kinase 3 (GSK3), which is involved in the regulation of cellular signaling pathways that control cell growth and proliferation. Furthermore, 4FA inhibits an enzyme that is needed for viral replication and can be used as a therapeutic agent against viruses such as hepatitis C virus.</p>Fórmula:C9H11FN6O4Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:286.22 g/mol2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxycytidine
<p>2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxycytidine is a novel nucleoside analog that has been shown to have anticancer, antiviral and antiretroviral activities. It binds to the ribonucleotide reductase enzyme and inhibits deoxyribonucleoside synthesis in cells. 2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxycytidine is also an activator of ribonucleotide reductase. This drug has been shown to be effective in treating leukemia, lymphoma, and breast cancer cells.</p>Fórmula:C23H21N3O5Pureza:Min. 95%Peso molecular:419.44 g/mol6-Amino-4-hydrazino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
<p>6-Amino-4-hydrazino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a modified nucleoside which has been shown to be active against HIV and other viruses. It is a phosphoramidate of 2'-deoxyadenosine 5'-monophosphate with an amino group at the 2' position. This compound inhibits the replication of DNA by binding to the enzyme reverse transcriptase and prevents the synthesis of viral DNA. 6-Amino-4-hydrazino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine also has anticancer properties, as it inhibits cell proliferation in vitro and in vivo.</p>Pureza:Min. 95%5'-O-p-Anisoyl-N4-benzoyl-3'-fluoro-2',3'-dideoxycytidine
<p>5'-O-p-Anisoyl-N4-benzoyl-3'-fluoro-2',3'-dideoxycytidine is a deoxyribonucleoside that has antiviral, anticancer, and novel properties. It has a CAS No. of 49811-91-7 and a molecular weight of 290.5 g/mol. The chemical formula for 5'-0-p-anisoyl-N4-benzoyl-3'-fluoro-2',3'-dideoxycytidine is C12H14FN2O9. It is synthesized by reacting 2,6-(1H,1'H)-benzoxazinones with 3' -deoxycytidines in the presence of phosphoric acid and anhydrous zinc chloride in methanol at room temperature to form the 5'-0 p anisoyl derivative, which is then reacted with</p>Fórmula:C24H22FN3O6Pureza:Min. 95%Peso molecular:467.45 g/mol2'-Deoxy-5'-O-DMT-uridine 3'-O succinate TEA
<p>2'-Deoxy-5'-O-DMT-uridine 3'-O succinate TEA salt is a modified nucleoside that is an activator for DNA synthesis. It can be used to synthesize oligonucleotides for use in the treatment of cancer and antiviral agents. 2'-Deoxy-5'-O-DMT-uridine 3'-O succinate TEA salt has been shown to inhibit viral replication by inhibiting the function of reverse transcriptase, which is an enzyme that catalyzes the conversion of RNA into DNA. This product has a CAS number, high purity, and high quality.</p>Pureza:Min. 95%2'-Deoxy-5'-O-DMT-5-fluoro-O4-(2,4,6-trimethylphenyl)uridine 3'-CE phosphoramidite
CAS:<p>2'-Deoxy-5'-O-DMT-5-fluoro-O4-(2,4,6-trimethylphenyl)uridine 3'-CE phosphoramidite is a nucleoside that has high purity and high quality. It is an anti cancer agent that inhibits the growth of cells by preventing DNA synthesis and RNA synthesis. This product is also used as an antiviral agent for influenza A virus and herpes simplex virus type 1 (HSV1). 2'-Deoxy-5'-O-DMT-5-fluoro-O4-(2,4,6-trimethylphenyl)uridine 3'-CE phosphoramidite is synthesized from ribonucleosides and deoxyribonucleosides. It can be modified to produce monophosphate, diphosphate or triphosphate forms of the nucleotide.</p>Fórmula:C48H56FN4O8PPureza:Min. 95%Peso molecular:866.95 g/mol2’-Amino-2’-deoxy-5’-O-DMT-5-methyluridine
CAS:<p>2’-Amino-2’-deoxy-5’-O-DMT-5-methyluridine is a novel nucleoside that has been modified to be phosphorylated on the 5' position. This modification provides the molecule with more stability in vivo and increases its anticancer potential. The synthesis of 2'-amino-2'-deoxy-5'-O-DMT-5 methyluridine is carried out by the conversion of 5'-O-(4,4'-dimethoxytrityl)-N,N-diisopropylphosphoramidite to 5'-O-(4,4'-dimethoxytrityl)-2',3',6'-triisopropylbenzoylphosphate. This compound can also inhibit viral replication by inhibiting dsRNA synthesis and is used to treat patients with chronic hepatitis B virus infection.<br>The molecule has high purity and high quality.</p>Pureza:Min. 95%7-Deazaadenosine- 2', 3'- dideoxy- 7[3- (trifluoroacetyl) amino] - 1- propyn- yl
CAS:<p>7-Deazaadenosine is a synthetic nucleoside that is used as an antiviral and antitumor agent. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. 7-Deazaadenosine also has antiviral activity, inhibiting viral DNA synthesis by interfering with the enzyme DNA polymerase. 7-Deazaadenosine has been shown to be more potent than other deoxyribonucleosides against various HIV strains, including HIV-1 group M and HIV-1 group O. This drug was originally developed for use as a chemotherapeutic agent but has since been used as a research reagent for studying the mechanism of action of various drugs on DNA.</p>Fórmula:C16H16F3N5O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:383.33 g/mol1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy) phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D- ribo-hex-5-enofu ranosyl]uracil
<p>5-Deoxy-2'-O-methylcytidine is a phosphoramidite nucleoside that has antiviral, anticancer, and antifungal properties. It is used as an activator in the synthesis of oligonucleotides and as a reagent for the synthesis of other nucleotide analogues. 5-Deoxy-2'-O-methylcytidine has been shown to have a novel mechanism of action, which targets DNA polymerase alpha and inhibits replication. This drug also has antiangiogenic activity, which may be due to its ability to inhibit the production of VEGF.</p>Pureza:Min. 95%2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite
<p>2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite is a novel, modified nucleoside. It is a monophosphate and can be used as antiviral, activator or diphosphate. It has been shown to inhibit the growth of cancer cells in vitro. 2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite also has activity against bacterial and viral pathogens and can be used for the synthesis of DNA, RNA, and other oligonucleotide compounds. This product is of high quality and purity with CAS No., Antiviral, Activator, diphosphate, Synthetic, Ribonuclesides, Deoxyribonucleosides.</p>Fórmula:C37H42FN4O6PPureza:Min. 95%Peso molecular:688.74 g/mol2'-O-tert-Butyldimethylsilyladenosine
CAS:<p>2'-O-tert-Butyldimethylsilyladenosine is a novel nucleoside. It is an anti-cancer and antiviral agent that is synthesized from ribonucleosides by the phosphoramidite method. 2'-O-tert-Butyldimethylsilyladenosine has been shown to be active against DNA polymerases, RNA polymerases, and enveloped viruses. This drug also inhibits cell proliferation in a variety of human tumor cells in vitro. 2'-O-tert-Butyldimethylsilyladenosine has been shown to exhibit anticancer activity by interfering with DNA synthesis and preventing the replication of damaged cells.</p>Pureza:Min. 95%N2-DMF-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite
<p>N2-DMF-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite is a nucleoside analog that inhibits the growth of cancer cells. It is a modified nucleoside that has been used to synthesize phosphorothioate oligonucleotides and has been shown to have antiviral and anticancer activities. This compound binds with high affinity to the active site of DNA polymerase, preventing incorporation of ribonucleosides into DNA. N2-DMF-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite is an activator that increases the rate of deoxyribonucleotide synthesis by DNA polymerase.</p>Pureza:Min. 95%2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine
CAS:<p>2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine is a novel phosphoramidite nucleoside that is an antiviral and anticancer agent. It can be used as a monophosphate or diphosphate. 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine has been shown to inhibit the replication of DNA, RNA, and protein synthesis. This compound also has an activating effect on the immune system by inducing lymphocyte proliferation and increasing NK activity. It inhibits the growth of viruses such as HIV and influenza A virus. The purity of 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine is high, with a CAS number of 11052282-2.</p>Fórmula:C39H37N5O7Pureza:Min. 95%Cor e Forma:PowderPeso molecular:687.76 g/mol2'-Deoxycytidine HCl
CAS:<p>2'-Deoxycytidine HCl is a nucleoside analogue that is used as a radiation sensitizer in the treatment of tumors. It is converted into 2'-deoxycytidine-5'-triphosphate by incorporation into DNA during replication and inhibits DNA synthesis. This compound has been shown to have anti-leukemic activity against murine leukemia virus (MLV) and murine sarcoma virus (MSV) in mice, although it does not inhibit the proliferation of Swiss-Webster mice. The protonated form of 2'-deoxycytidine HCl has been observed using nuclear magnetic resonance spectroscopy, with a cyclohexane ring as the proton acceptor. The monosodium salt also forms a stable complex with amino groups, which may be due to its acidic ph.</p>Fórmula:C9H13N3O4·HClPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:263.68 g/mol3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate
CAS:<p>3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate is an antiviral and anticancer agent that is used for the synthesis of DNA and RNA. It is a novel nucleoside analog that has been modified to be activated by phosphoramidite chemistry. 3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate is synthesized from 2,6-diisopropylaniline, methyl 3-(aminomethyl)-1H-pyrrole-2,4-dicarboxylate, and propylamine in cyclohexane at reflux.</p>Fórmula:C13H22N3O14P3Pureza:Min. 95%Peso molecular:537.25 g/mol3'-Amino-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-3'-deoxyadenosine
<p>3'-Amino-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-3'-deoxyadenosine is a nucleoside that is synthesized by the modification of deoxyadenosine. It has antiviral and anticancer properties, as well as other novel applications. The synthesis of this compound can be achieved in two steps: first, the amino group is attached to the 3' carbon atom of the sugar ring by reacting with N6-(benzoyl)adenine. In the second step, a silyl group is attached to the 5' carbon atom of the sugar ring by reacting with tert-butyldimethylchlorosilane and DMT (dimethoxytrityl).</p>Fórmula:C44H50N6O6SiPureza:Min. 95%Peso molecular:786.99 g/mol2'-Deoxy-N6-DMF-5'-O-MMT-adenosine 3'-CE phosphoramidite
CAS:<p>2'-Deoxy-N6-DMF-5'-O-MMT-adenosine 3'-CE phosphoramidite is a high purity, diphosphate nucleotide analog. It is an anticancer drug that inhibits DNA synthesis and can be used to treat cancer. The 2'-deoxy-N6-DMF moiety has been shown to inhibit the activity of DNA polymerase and other enzymes involved in DNA replication. This compound also has a novel mechanism of action that is not present in any other known anticancer drugs. CAS No. 195375-66-7.br>br>2'-Deoxy-N6-DMF 5'-O-MMT adenosine 3'-cephosphoramidite is often used as a building block for oligonucleotide synthesis because it is resistant to the removal of phosphate groups by alkaline phosphatases. The lack of phosphate groups makes this compound more stable than standard nucleotides</p>Fórmula:C42H51N8O5PPureza:Min. 95%Peso molecular:778.9 g/molN2-Acetyl-6-[2-(4-nitrophenyl)ethoxy]-2'-O-trifluoromethanesulfonyl-3',5'-di-O-tritylguanosine
<p>N2-Acetyl-6-[2-(4-nitrophenyl)ethoxy]-2'-O-trifluoromethanesulfonyl-3',5'-di-O-tritylguanosine is a novel nucleotide that is activated by the addition of 2'-deoxyribonucleosides and has antiviral activity. It was synthesized from 2'-deoxynucleoside 5'-triphosphates and 4,4'-dimethoxytrityl chloride in high yield. The compound is also shown to have anticancer activity against human leukemia cells and breast cancer cells.</p>Pureza:Min. 95%5-Azacytidine
CAS:<p>An azanucleoside and epigenetic modulator that interferes with nucleic acid metabolism. The compound gets incorporated into RNA and inhibits ribonucleotide reductase subunit RRM2 in leukemia cell lines. Intracellularly, 5-azacytidine can get converted into 2′-deoxy-5-azacytidine (decitabine) and subsequently incorporated in DNA, where it irreversibly inhibits DNMT1 methyltransferase. In human epithelial cell lines, this compound decreases Src-activated expression of a histone chaperone CAF1 and inhibits cell motility and invasiveness.</p>Fórmula:C8H12N4O5Pureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:244.21 g/mol4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D- ribofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine
<p>4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-beta-D-ribofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine is a synthetic activator that selectively activates the transcription of genes in cells. It has been shown to have anticancer activity and may be useful as a therapeutic agent for the treatment of certain cancers. 4C 7 (2dEB 3,5BT) 5I is also known to be an antiviral agent against HIV and influenza virus. The modification on the 2'-deoxyribose sugar moiety can enhance both activation and antiviral activities.</p>Pureza:Min. 95%5-Methylcytidine-5'-monophosphate
CAS:<p>5-Methylcytidine-5'-monophosphate is a nucleotide that is an intermediate in the synthesis of DNA. It is a neutral form and has been sequenced. 5-Methylcytidine-5'-monophosphate is found in cellular components, such as mitochondria and nuclei. The biochemical properties of this molecule are dependent on its methylation state. This molecule also plays a role in mitochondrial functions and nuclear DNA modifications.</p>Fórmula:C10H16N3O8PPureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:337.22 g/mol5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt
CAS:<p>5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt (BrdUMP) is an antiviral agent that inhibits the synthesis of DNA. It has shown activity against herpes simplex virus and cytomegalovirus, and has been used in the treatment of Kaposi's sarcoma. BrdUMP is a monophosphate prodrug that is activated by ribonucleoside diphosphates to inhibit the production of viral DNA and RNA. This drug has anticancer properties due to its ability to inhibit cell division. BrdUMP is synthesized from 2'-deoxyuridine-5'-monophosphate, which is obtained from uracil or thymine. The CAS number for this compound is 51432-32-7, and it can be used as a phosphoramidite for the preparation of DNA, RNA, or oligonucleotide analogues.</p>Fórmula:C9H12BrN2O8PNa2Pureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:433.06 g/mol2',3'-Dideoxyinosine
CAS:<p>2',3'-Dideoxyinosine is a purine analog that can suppress human immunodeficiency virus (HIV) replication after intracellular metabolic conversion</p>Fórmula:C10H12N4O3Pureza:Min. 95 Area-%Cor e Forma:White Off-White PowderPeso molecular:236.23 g/molDihydrozeatin riboside
CAS:<p>Dihydrozeatin riboside is a cytokinin, a group of plant hormones that regulate various aspects of plant growth and development. It is found in the form of an ester, dihydrozeatin riboside, which is produced by the action of trifluoroacetic acid on zeatin. The natural function of this hormone is to stimulate cell division in plants, but it has also been shown to have antibacterial effects against bacterial strains such as Bacillus subtilis and Escherichia coli. Dihydrozeatin riboside inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction</p>Fórmula:C15H23N5O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:353.37 g/mol1-(2’-Deoxy-2’-fluoro-b-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil
CAS:<p>1-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil is a novel, anticancer drug. It is active against both RNA and DNA viruses, such as HIV, influenza virus and herpes virus. 1-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil has been shown to be an activator for phosphoramidites in aqueous solution. This compound is of high purity with CAS No. 2072145–25–4. It is also a synthesized, monophosphate nucleoside that can be used in the production of modified nucleosides for therapeutic purposes or as antiviral agents</p>Pureza:Min. 95%Caged GTP
CAS:<p>Caged GTP is a modified nucleotide that is biologixally inactive until exposed to ultraviolet light, where GTP is released.</p>Fórmula:C18H23N6O16P3Pureza:Min. 95 Area-%Cor e Forma:White Off-White PowderPeso molecular:672.33 g/mol2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine
CAS:<p>2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine is a monophosphate nucleoside that is used as an antiviral and anticancer drug. It inhibits the synthesis of DNA, RNA, and proteins by acting as a chain terminator. 2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine inhibits viral replication by blocking the formation of viral DNA. This compound is also used for the treatment of cancerous cells. 2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine has shown to be effective against leukemia cells in culture.<br>2'-Deoxy -2' -fluoro N4 benzoyl 5 methyl cytidine has been synthesized with high purity and is available in a variety of modifications including phosphoramidites and deoxyribonucleosides.</p>Pureza:Min. 95%5'-Tosyladenosine
CAS:<p>Adenosine is a naturally occuring nucleoside and an essential building block in DNA synthesis. The tosyl protected adenosine at the 5' position, 5-tosyladenosine, allows for selective functionalistion at the the 3' and 4' positions, resulting in derivatised nucleotides that can incorporated into modified RNA which is an area of therapeutics that is currently expanding.</p>Fórmula:C17H19N5O6SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:421.43 g/molAcetyl hypoxanthine
CAS:<p>Acetyl hypoxanthine is an inorganic compound that has a cyclophosphate group. It can be synthesized from the reaction of acetic acid and 6-chloropurine, which is activated with trifluoroacetic acid and irradiated with ultraviolet light. Acetyl hypoxanthine can then be synthesized by ammonolysis of chloroacetone using ammonia or by chlorinating acetylene with chlorine. The advantages of this compound are its high yield and low cost.</p>Fórmula:C7H6N4O2Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:178.15 g/mol8-Hydroxyadenosine
CAS:<p>8-Hydroxyadenosine (8-OHdG) is a purine nucleoside that is formed as a result of oxidative DNA damage. It is not an essential metabolite because it can be synthesized de novo. 8-OHdG has been shown to have potent anti-tumor activity in vitro and in vivo, which may be due to its ability to inhibit DNA replication. The biological effects of 8-OHdG are attributed to its ability to form hydrogen bonds with guanine residues in the double helix, and electrochemical detectors have been developed for its detection.</p>Fórmula:C10H13N5O5Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:283.25 g/mol5'-O-p-Anisoyl-2'-deoxyuridine
<p>5'-O-p-Anisoyl-2'-deoxyuridine is a novel activator that is an analogue of pyrimidine and has been synthesized for the first time. It belongs to the group of nucleosides and has been modified chemically. This compound can be used as a pharmaceutical drug for the treatment of cancer or viral infections.</p>Fórmula:C17H18N2O7Pureza:Min. 95%Peso molecular:362.33 g/molN6-Benzyladenosine 5'-monophosphate sodium salt monohydrate
CAS:<p>N6-Benzyladenosine 5'-monophosphate sodium salt is a nucleoside that is not identified. It has been shown to be metabolized by adenosine deaminase and may have antitumor activity. N6-Benzyladenosine 5'-monophosphate sodium salt is also a radioactively labeled adenine analog that has been used in the study of metabolic pathways.</p>Fórmula:C17H18N5Na2O7P·H2OPureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:499.32 g/molTFA-aa-dUPhosphoramidite
<p>TFA-aa-dUPhosphoramidite is a high quality, novel DNA phosphoramidite. It is used for the synthesis of deoxyribonucleosides and ribonucleosides. TFA-aa-dUPhosphoramidite has been shown to be an activator in the synthesis of RNA and DNA, and it is also resistant to degradation by nucleases. This product has CAS No.</p>Fórmula:C44H51N5O9PPureza:Min. 95%Peso molecular:824.88 g/mol9-(β-D-Xylofuranosyl)adenine
CAS:<p>9-(β-D-Xylofuranosyl)adenine is a nucleoside analog that inhibits the activity of adenine nucleotide. It has been shown to be effective against a wide range of viruses and bacteria, including HIV, herpes simplex virus, influenza A virus, and Mycobacterium tuberculosis. The chemical structure of 9-(β-D-Xylofuranosyl)adenine resembles that of adenosine and this similarity confers inhibitory properties on it. 9-(β-D-Xylofuranosyl)adenine is an analog of adenosine. The steric interactions between the intramolecular hydrogen bonds in 9-(β-D-Xylofuranosyl)adenine are weaker than those in adenosine, which allows it to bind more easily with the enzyme responsible for the conversion of adenosine to inosinic acid. This inhibition prevents the formation of ATP from AMP, leading</p>Fórmula:C10H13N5O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:267.24 g/mol3',5'-Di-O-acetyl-5-bromo-2'-deoxyuridine
CAS:<p>Please enquire for more information about 3',5'-Di-O-acetyl-5-bromo-2'-deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C13H15BrN2O7Pureza:Min. 95%Cor e Forma:PowderPeso molecular:391.18 g/mol3’-O-tert-butyldimethylsilyl-5’-O-DMT-N1-methylpseudouridine
CAS:<p>3′-O-tert-butyldimethylsilyl-5′-O-DMT-N1-methylpseudouridine is a synthetic nucleoside that is used in the synthesis of deoxyribonucleosides. It is an activator nucleoside that has antiviral activity and provides high purity, novel monophosphate nucleosides, and modified nucleosides. 3′-O-tert-butyldimethylsilyl-5′-O-DMT-N1 methylpseudouridine has CAS No. 875302–43–5 and can be used for the synthesis of phosphoramidites or ribonucleotides.</p>Pureza:Min. 95%3'-Amino-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine
<p>This product is a novel nucleoside analog with antiviral, anticancer and antiretroviral activities. It is an activator of ribonucleosides and deoxyribonucleosides. This product is synthesized by the phosphoramidite method. The purity of this product is greater than 98%.</p>Fórmula:C24H22N6O4Pureza:Min. 95%Peso molecular:458.47 g/mol5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine
CAS:<p>5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine is a monophosphate antiviral agent. It has been shown to inhibit the activity of DNA and RNA polymerases in vitro. The drug is novel, and its antiviral properties have not been tested in vivo. 5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine has been synthesized using phosphoramidites and was found to be of high quality and purity. It has also been modified at the 2' position with an acetyl group and at the 3' position with a levulinoyl group.</p>Pureza:Min. 95%3’-b-Amino-2’,3’-dideoxy-5-methyl-5’-O-trityluridine
CAS:<p>3’-b-Amino-2’,3’-dideoxy-5-methyl-5’-O-trityluridine is an antiviral nucleoside that can inhibit the synthesis of DNA in cells. It has been shown to be active against Hepatitis B and Human Immunodeficiency Virus (HIV). This drug has also been shown to have anticancer properties. 3’-b-Amino-2’,3’-dideoxy-5-methyl-5’-O -trityluridine is a novel nucleoside modified at the 5′ position with a trityl group and with an amino group at the 3′ position. 3′ b -amino 2 ′,3 ′ -dideoxy 5 ′ -methyl 5 ′ -O trityl uridine is water soluble and stable in acid conditions.</p>Pureza:Min. 95%2-Acetamido-6-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
CAS:<p>2-Acetamido-6-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a modified purine nucleoside, protected with acetyl groups, which protect the sugar during chemical reactions. This compound is based on a purine ring and also contains an acetamido group at position 2, a chlorine atom at position 6 and a β-D-ribofuranosyl sugar.</p>Fórmula:C18H20ClN5O8Pureza:Min. 95%Cor e Forma:PowderPeso molecular:469.83 g/mol6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydrazino-1H-pyrazolo[3,4-d]pyrimidine
<p>6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydrazino-1H-pyrazolo[3,4-d]pyrimidine (6ADRP) is a synthetic nucleoside that is used as an activator of ribonucleosides and diphosphates in DNA synthesis. 6ADRP has antiviral activity against HIV and herpes simplex virus type 1. It binds to the viral DNA polymerase and prevents the addition of nucleotides to the growing DNA strand. 6ADRP is phosphorylated by T7 kinase to form the active metabolite, 6-amino-1-(2'-deoxy-[alpha]-D-ribofuranosyl)-5'-triphosphate (6ATP), which inhibits viral replication by preventing the formation of RNA primers.</p>Pureza:Min. 95%2-Iodoadenosine
CAS:<p>2-Iodoadenosine is a chemical compound that is produced from the oxidation of uridine. It is used in the synthesis of peptides, which are important for biological processes like signal transduction and cell growth. 2-Iodoadenosine can be made by coupling other molecules to an adenosine molecule. This process involves a cross-coupling reaction with palladium catalysts or hydroxylation reactions with sodium borohydride. The resulting product has been shown to have anticancer and anti-microbial activities against protozoan parasites and cyclic peptide structures.</p>Fórmula:C10H12IN5O4Pureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:393.14 g/molAdenosine 5'-difluoromethylene-5'-triphosphate triethylammonium salt
<p>Adenosine 5'-difluoromethylene-5'-triphosphate triethylammonium salt is a novel nucleotide activator that has antiviral, anticancer, and ribonucleoside activities. This activator is a phosphoramidite monomer with an adenine base. The pharmaceutical industry uses this activator as a starting material in the synthesis of anticancer drugs and antiviral drugs. It is also used as a reagent in the production of modified DNA and RNA molecules for use in gene therapy and drug discovery.</p>Pureza:Min. 95%N6-Benzoyl-8-hydroxy-2'-O-methyladenosine
<p>N6-Benzoyl-8-hydroxy-2'-O-methyladenosine is a nucleoside analogue that inhibits the replication of RNA and DNA. It is a monophosphate, which can be converted to a diphosphate through phosphorylation. N6-Benzoyl-8-hydroxy-2'-O-methyladenosine has been shown to inhibit cancer cells and may have potential for use in antiviral therapy. This compound was synthesized from 2,4,5,6 tetrahydrobenzyl alcohol and 2'-deoxyadenosine. The CAS number for this compound is 79430-89-1.</p>Pureza:Min. 95%7-(2-C-Methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
CAS:<p>7-(2-C-Methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine (Ampyra) is a synthetic nucleoside activator of the deoxyribonucleoside monophosphate (dNMP) and dNMP diphosphate (dNDP) pathways. It has antiviral and anticancer activities, as well as an inhibitory effect on DNA synthesis by blocking the polymerization of deoxyribonucleotides.<br>It is also an inhibitor of histone acetyltransferase and may be useful in the treatment of Alzheimer's disease. Ampryra is a novel compound with high purity and high quality. It is phosphoramidite that can be used for the preparation of oligodeoxynucleotides for use in DNA sequencing or gene therapy.</p>Pureza:Min. 95%2-Chloro-6-O-methylinosine
CAS:<p>2-Chloro-6-O-methylinosine is a modified nucleoside analog. Its structure is based on inosine and at position 2 a chlorine atom replaces the hydrogen. At position 6, the keto oxygen (normally part of the purine ring) is O-methylated, forming a methoxy group (-OCH₃)</p>Fórmula:C11H13ClN4O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:316.7 g/molN-Benzoyl-2'-deoxy-2'-fluoroadenosine, 3'-(hydrogen phosphonate)
CAS:<p>N-Benzoyl-2'-deoxy-2'-fluoroadenosine, 3'-(hydrogen phosphonate) is a novel nucleoside that inhibits the replication of virus by binding to viral RNA. It is synthesized by reacting 2'-deoxy-2'-fluoroadenosine with pentafluorophenyl phosphate in the presence of an activator such as dicyclohexylcarbodiimide or N-hydroxysuccinimide. The synthesis of N-benzoyl-2'-deoxy-2'-fluoroadenosine, 3'-(hydrogen phosphonate) can be accomplished using commercially available nucleosides and phosphoramidites.</p>Pureza:Min. 95%2,3'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine
<p>2,3'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine is a synthetically modified thymidine analog for use in research</p>Pureza:Min. 95%Cor e Forma:White to off-white solid.2'-Deoxy-2'-fluoroadenosine
CAS:<p>2’-Deoxy-2’-fluoro nucleosides and nucleotides have been shown to demonstrate anti-viral activity against influenza, SARS and HIV. More specifically the phosphonate of 2'-Deoxy-2'-fluoroadenosine has been evaluated as an inhibitor of Hepacivirus C (HCV).</p>Fórmula:C10H12FN5O3Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:269.24 g/mol5'-O-p-Anisoyl-N6-benzoyl-2'-O-tert-butyldimethylsilyladenosine 3'-CE phosphoramidite
<p>5'-O-p-Anisoyl-N6-benzoyl-2'-O-tert-butyldimethylsilyladenosine 3'-CE phosphoramidite is an anticancer compound. It is a novel nucleoside analog that is being studied for its potential as a chemotherapy drug. This compound has been shown to inhibit the proliferation of cancer cells by interfering with DNA synthesis and RNA transcription, leading to cell death. 5'-O-p-Anisoyl-N6-benzoyl-2'-O-tert-butyldimethylsilyladenosine 3'-CE phosphoramidite also inhibits viral replication by inhibiting viral RNA polymerase, which is required for viral replication.</p>Fórmula:C40H54N7O8PSiPureza:Min. 95%Peso molecular:819.98 g/mol2'-Deoxy-6-thioguanosine-5'-monophosphate
CAS:<p>Azathioprine is a drug that suppresses the immune system and is used to treat autoimmune disorders such as rheumatoid arthritis, lupus erythematosus, and inflammatory bowel disease. It is an immunosuppressant that prevents the formation of antibodies by blocking the enzyme thiopurine S-methyltransferase. Azathioprine is metabolized in the liver to 6-mercaptopurine, which has been shown to cause leukopenia. The genetic polymorphism of this enzyme can lead to differences in the metabolism and toxicity of azathioprine therapy.</p>Fórmula:C10H14N5O6PSPureza:Min. 95%Peso molecular:363.29 g/mol1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N4-benzoylcytidin-1-yl)-D-altro-hexitol
CAS:<p>1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N4-benzoylcytidin-1-yl)-D-altro-hexitol is a synthetic nucleoside analog for use in research</p>Fórmula:C24H22N2O7Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:450.45 g/mol2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine
<p>2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine (2DFO) is a novel nucleoside analog that is phosphorylated to 2DFP, which is an antiviral drug that has been shown to inhibit the replication of HIV. 2DFO inhibits the activity of DNA polymerase, RNA polymerase, and reverse transcriptase, preventing the synthesis of viral DNA and RNA. This drug also inhibits the activity of human topoisomerase II alpha and beta, which are enzymes involved in replication and transcription. 2DFO binds to purine nucleosides by competitive inhibition at the enzyme active site, preventing the formation of ribonucleotides from deoxyribonucleosides.</p>Pureza:Min. 95%5'-O-p-Anisoyl-3'-azido-2',3'-dideoxyuridine
<p>5'-O-p-Anisoyl-3'-azido-2',3'-dideoxyuridine is a compound that inhibits DNA synthesis and viral replication. It is an antiviral agent that inhibits the activation of virus by blocking the incorporation of deoxyribonucleotide triphosphates into viral DNA chains. This compound also has anticancer activity, which may be due to its ability to inhibit RNA synthesis in tumor cells.</p>Fórmula:C17H17N5O6Pureza:Min. 95%Peso molecular:387.35 g/molAdenosine 3',5'-cyclic monophosphate sodium salt
CAS:<p>Second messenger in intracellular signal transduction</p>Fórmula:C10H11N5NaO6PPureza:Min. 97 Area-%Cor e Forma:White PowderPeso molecular:351.19 g/molN-Acetyl-2'-O-[(tert-butyl)dimethylsilyl]-5'-O-DMT-6'-O-methylguanosine-3'-CE phosphoramidite
CAS:<p>N-Acetyl-2'-O-[(tert-butyl)dimethylsilyl]-5'-O-DMT-6'-O-methylguanosine-3'-CE phosphoramidite is a nucleoside and nucleotide analog. It is synthesized by reacting 2'-deoxyguanosine with acetyl chloride, 5'-dimethoxytrityl chloride, and 3'-Ce phosphoramidite in an organic solvent. N-Acetyl-2'-O-[(tert-butyl)dimethylsilyl]-5'-O-DMT-6'-O-methylguanosine has been shown to inhibit the growth of cancer cells and viruses in cell culture studies. It is also a potent inhibitor of HIV replication in vitro.</p>Fórmula:C49H66N7O9PSiPureza:Min. 95%Cor e Forma:PowderPeso molecular:956.15 g/mol2'-Deoxyadenosine 5'-a-thiotriphosphate sodium salt
<p>2'-Deoxyadenosine 5'-a-thiotriphosphate sodium salt is an antiviral nucleotide analog that has been modified to have a novel structure. It is phosphorylated in vivo to form 2'-deoxyadenosine 5'-a-thiotriphosphate. The nucleoside can inhibit viral DNA synthesis and help prevent the spread of HIV, herpes virus type I, herpes virus type II, influenza virus, and other viruses. This compound also has anticancer activity and has been shown to be effective against leukemia cells.</p>Pureza:Min. 95%5-Carbamoylmethyluridine
CAS:<p>5-Carbamoylmethyluridine is a nucleoside that is structurally related to uridine. It is synthesized from uridine by methyl esterification with carbamic acid and methoxycarbonyl chloride. 5-Carbamoylmethyluridine interacts with actin filaments and has been shown to alter the expression of messenger RNA in eukaryotes. 5-Carbamoylmethyluridine also acts as a competitive inhibitor of the formation of a ternary complex, which includes ATP, GTP, and UTP, at the level of ribonucleotide reductase. This inhibition leads to decreased synthesis of messenger RNA in cells.</p>Fórmula:C11H15N3O7Pureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:301.25 g/mol3'-Azido-5'-O-benzoyl-3'-deoxythymidine
CAS:<p>3'-Azido-5'-O-benzoyl-3'-deoxythymidine is a novel antiviral agent that is synthesized by modifying the structure of thymidine. It has been shown to have high antiviral activity against HIV and other viruses in vitro. 3'-Azido-5'-O-benzoyl-3'-deoxythymidine also inhibits tumor growth in animal models and may be useful as an anticancer drug. This compound is found to be active against a number of cancers, including leukemia, colon cancer, and prostate cancer. 3'-Azido-5'-O-benzoyl-3'-deoxythymidine is phosphoramidites for DNA synthesis, which can be used in the production of ribonucleosides or deoxyribonucleosides.</p>Fórmula:C17H19N5O4Pureza:Min. 95%Peso molecular:357.36 g/mol2-Amino-2'-deoxy-2'-fluoroadenosine
CAS:<p>2-Amino-2'-deoxy-2'-fluoroadenosine is a modified nucleoside. Fluorination modifications can make molecules have increased resistance to enzymatic degradation, which has useful applications in drug development. The extra amino group could also enhance binding properties or alter biological activity.</p>Fórmula:C10H13FN6O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:284.25 g/mol2’-Deoxy-N1-methylguanosine
CAS:Produto Controlado<p>2’-Deoxy-N1-methylguanosine is a modified purine nucleoside composed of a N¹-methylguanine, a guanine base where a methyl group is attached to the nitrogen at position 1 (N¹). This methylation blocks normal Watson-Crick base pairing, especially with cytosine, and can affect RNA structure and function. It also contains a 2′-Deoxyribose and has possible research applications</p>Fórmula:C11H15N5O4Pureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:281.27 g/molN6-Benzoyl-3'-deoxy-5'-O-DMT-cytidine 2'-CE phosphoramidite
CAS:<p>N6-Benzoyl-3'-deoxy-5'-O-DMT-cytidine 2'-CE phosphoramidite is a Ribonucleoside, Novel, High quality, Activator, Deoxyribonucleosides, Modified, CAS No. 157327-96-3. It is one of the main ingredients in the synthesis of DNA monophosphate and diphosphate. It is also used as an anticancer and antiviral agent.</p>Fórmula:C46H52N5O8PPureza:Min. 95%Peso molecular:833.91 g/mol3'-Deoxy-3'-fluoro-5'-O-toluoylcytidine
CAS:<p>3'-Deoxy-3'-fluoro-5'-O-toluoylcytidine is a monophosphate nucleoside of cytidine. It is a phosphoramidite building block for the synthesis of DNA, an antiviral and anticancer agent. 3'-Deoxy-3'-fluoro-5'-O-toluoylcytidine has been shown to inhibit the replication of HIV and herpes simplex virus (HSV) in cell cultures and to induce apoptosis in cancer cells by inhibiting protein synthesis and inducing oxidative stress. This nucleoside is synthesized from deoxythymidine 5' phosphate using phosphorus pentoxide as oxidizing agent, followed by a reaction with toluene. The novel 3'-deoxy-3'-fluoro-5'-O-toluoylcytidine can be used as an activator for other modified nucleotides in DNA synthesis or as scaffold for the</p>Pureza:Min. 95%Nelarabine
CAS:<p>Nelarabine is a drug that prevents the growth of cells by inhibiting the bcr-abl kinase, which is an intracellular target. This drug has been shown to be effective against pediatric patients with t-cell acute lymphoblastic leukemia and adults with chronic myeloid leukemia. Nelarabine has minimal toxicity in humans and is not toxic to healthy cells. It has been shown to have anti-inflammatory properties and may be used as a biomarker for autoimmune diseases. Nelarabine also inhibits angiogenesis, which may be due to its effects on nuclear DNA.</p>Fórmula:C11H15N5O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:297.27 g/mol6-Amino-2,5-dihydro-2-(b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one
CAS:<p>6-Amino-2,5-dihydro-2-(b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one is a novel chemical. It is a nucleoside analog that has been shown to inhibit the growth of cancer cells in vitro and in vivo. 6-Amino-2,5-dihydro-2-(b-D ribofuranosyl)-4H pyrazolo[3,4 d]pyrimidin 4 one has also been shown to inhibit viral replication. It is phosphoramidites that are modified with bifunctional linkers for coupling to DNA or RNA molecules. 6 amino 2 5 dihydro 2 (b D ribofuranosyl) 4 H pyrazolo 3 4 d pyrimidine 4 one has high purity and high quality.</p>Pureza:Min. 95%N-Phenylpyridin-4-amine
CAS:<p>N-Phenylpyridin-4-amine is a tautomeric compound that has been shown to inhibit the growth of cancer cells. It is able to bind to tyrosine kinase and inhibit its activity, which affects the proliferation of cancer cells. N-Phenylpyridin-4-amine also inhibits mitochondrial functions by inhibiting cytochrome c oxidase. This drug also has an anti-inflammatory effect, inhibiting the production of cytokines such as IL1β, IL6, and TNFα. The biological function of N-Phenylpyridin-4-amine is not yet fully understood. It may be due to the inhibition of protein tyrosine phosphatases (such as PTP1B), which are involved in insulin signalling pathways.</p>Fórmula:C11H10N2Pureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:170.21 g/molCytarabine hydrochloride
CAS:<p>Anti-viral; anti-neoplastic</p>Fórmula:C9H13N3O5·HClPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:279.68 g/mol5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine
CAS:<p>5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine is an analogue of adenosine that has inhibitory activities on the biosynthetic pathway of polyamines. It has been shown to have a cytostatic effect on murine leukemia cells in vitro. 5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine inhibits the production of polyamines by interfering with the enzyme responsible for their biosynthesis, ornithine decarboxylase. 5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine also inhibits the growth of murine leukemia cells and other leukemia cell lines, including L1210 and MM1.</p>Fórmula:C11H14FN5O3SPureza:Min. 95%Peso molecular:315.33 g/mol5'-O-p-Anisoyl-2'-deoxyuridine 3'-CE phosphoramidite
<p>5'-O-p-Anisoyl-2'-deoxyuridine 3'-CE phosphoramidite is an anticancer nucleoside analog that inhibits viral replication. It is a modified nucleoside with a 5' anisoyl group and a 2' deoxyuridine moiety. This compound is synthesized by reacting the 5'-O-p-anisoyl-2'-deoxyuridine 3'-cyclohexylphosphate with <br>phosphorus oxychloride to form the 5'-O-p-anisoyl-2'-deoxyuridine 3'-cyanoethyl phosphoramidite, which can be used for the synthesis of DNA or RNA. The phosphoramidite can also be used as an activator in polymerase chain reactions (PCR).</p>Fórmula:C26H35N4O8PPureza:Min. 95%Peso molecular:562.55 g/mol1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)thymine
CAS:<p>1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)thymine is a nucleoside analog with a modified ribofuranosyl sugar, which includes a 2'-O-4'-C-methylene bridge that constrains the sugar conformation.</p>Fórmula:C11H14N2O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:270.24 g/molN4-Acetyl-5'-O-DMT-2'-O-methylcytidine
CAS:<p>N4-Acetyl-5'-O-DMT-2'-O-methylcytidine is a cytidine analogue that has been synthesized to be used as an enzyme-linked probe. It is labelled with biotin and can be detected by binding to an antibody which has been labelled with a fluorescent tag. Cytidine analogues are synthesized on a solid phase and then cleaved from the support material. The spacer arm is added to the 5' end of the nucleotide and the 3'-OH group is modified with 2'-O-methyl groups. N4-Acetyl-5'-O-DMT-2'-O-methylcytidine has been shown to be sensitive in techniques such as solid phase synthesis, nucleic acid research, and immunoassays.</p>Fórmula:C33H35N3O8Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:601.65 g/mol5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine
CAS:<p>5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine is a nucleoside analog. It is synthesized by substituting the hydroxyl group of uridine with a fluorine atom and the 2' position of ribose with a 5'-O-acetyl group. This modification prevents the incorporation of this nucleoside into DNA or RNA, making it an effective antiviral and anticancer agent. 5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine has been shown to be highly active against tumor cells but not normal cells in vitro.</p>Fórmula:C11H11N2O5Pureza:Min. 95%Peso molecular:251.22 g/mol2'-Deoxy-5'-O-pixyluridine
<p>2'-Deoxy-5'-O-pixyluridine (2DPU) is a novel, synthetic nucleoside that is an active ingredient in antiviral and anticancer drugs. 2DPU has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) by inhibiting the viral enzyme HIV reverse transcriptase. The phosphoramidite form of 2DPU is used as a building block for DNA synthesis and for the synthesis of other nucleosides. The monophosphate form of 2DPU is used in the synthesis of antiviral drugs, including acyclovir, zidovudine, and ribavirin.</p>Fórmula:C28H24N2O6Pureza:Min. 95%Peso molecular:484.51 g/mol5'-Azido-5'-deoxy-2'-O-methyluridine
CAS:<p>5'-Azido-5'-deoxy-2'-O-methyluridine is a nucleoside that is a modified version of 2'-deoxyuridine. It is synthesized from uridine, which is converted to 5'-azidouridine via the action of azidase. 5'-Azido-5'-deoxy-2'-O-methyluridine has antiviral activity and can be used as an activator of DNA polymerases. The monophosphate form of this compound can be phosphoramidated to give the corresponding diphosphates, which are used in DNA synthesis to produce double stranded DNA.</p>Fórmula:C10H13N5O5Pureza:Min. 95%Peso molecular:283.24 g/mol6-(3,3-Dimethylallylamino)-9-(b-D-ribofuranosyl)purine
CAS:<p>6-(3,3-Dimethylallylamino)-9-(b-D-ribofuranosyl)purine is an energy metabolism agent that mimics cytokinin, a plant hormone. It has been shown to affect the angiogenic process and induce apoptosis in HL60 cells through the pro-apoptotic protein Bax. 6-(3,3-Dimethylallylamino)-9-(b-D-ribofuranosyl)purine has also been used as a model system to study the structure of dna, which is important for understanding how it replicates. 6-(3,3-Dimethylallylamino)-9-(b-D-ribofuranosyl)purine is structurally similar to adenosine and binds to the A3 receptor with high affinity. This drug is active as an analogue of adenosine and may be useful for treating diseases such as heart disease or diabetes.</p>Fórmula:C15H21N5O4Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:335.37 g/mol2'-Deoxycytidine-5'-monophosphate
CAS:<p>2'-Deoxycytidine-5'-monophosphate (dCMP) is a nucleotide that is synthesized by the enzyme cytidine monophosphate synthetase. It has been shown to inhibit the activity of many enzymes, including those involved in DNA synthesis and repair. The incorporation of dCMP into DNA can be used as a probe for studying various biological processes, such as radiation damage and cellular physiology. In addition, it has been shown that dCMP inhibits the growth of human osteosarcoma cells. This drug is also used in combination preparations with other drugs, such as with 5-fluorouracil and doxorubicin, to treat cancer tumors.</p>Fórmula:C9H14N3O7PPureza:Min. 99 Area-%Cor e Forma:White PowderPeso molecular:307.2 g/mol4'-C-Fluoroadenosine
CAS:<p>4'-C-Fluoroadenosine is a fluorine-substituted analog of adenosine, which has been shown to have minimal toxicity in animals. 4'-C-Fluoroadenosine inhibits the uptake of trypanosomes by macrophages and has been shown to be effective in treating Leishmania donovani infections in mice. Its mechanism of action is not yet clear, but it may involve inhibiting the enzymatic activity of enzymes involved in the metabolism of adenosine and/or enhancing the activity of those that are involved in catalysing adenoside triphosphate synthesis.</p>Pureza:Min. 95%3’-Deoxy-5-fluoro-3’-methyluridine
CAS:<p>3’-Deoxy-5-fluoro-3’-methyluridine is a nucleoside that has antiviral and anticancer properties. It is synthesized from 5-fluorouracil, which is a prodrug that is activated by 3’-deoxy-5-fluoro-3’-methyl uridine to produce 5′,6′ difluorodeoxyadenosine. This compound can be used in the treatment of hepatitis B virus and hepatitis C virus infections. 3’-Deoxy-5-fluoro-3’ methyluridine has also been shown to inhibit the growth of cancer cells in vitro.</p>Pureza:Min. 95%3'-Azido-3'-deoxythymidine-5'-monophosphate lithium salt - 100 mM aqueous solution
CAS:<p>3'-Azido-3'-deoxythymidine-5'-monophosphate lithium salt - 100 mM aqueous solution is an azidothymidine (AZT) analog that inhibits HIV replication. AZT is a nucleoside reverse transcriptase inhibitor that blocks the progression of HIV by preventing the virus from duplicating its DNA. This product has been shown to be effective in treating AIDS and related diseases, as well as other infectious diseases such as hepatitis B and C. 3'-Azido-3'-deoxythymidine-5'-monophosphate lithium salt - 100 mM aqueous solution is often used in combination with other drugs to increase their efficacy. It has also been shown to be an effective chemotherapeutic agent against cancer cells.</p>Fórmula:C10H14N5O7P·xLiPureza:Min. 95%Peso molecular:347.22 g/mol2'-Deoxynucleoside-5'-triphosphate mixture
<p>2'-Deoxynucleoside-5'-triphosphate mixture are a group of phosphorylated compounds that are used in the synthesis of DNA. They are used as antiviral and anticancer agents, as well as activators for certain enzymes. They are also used to synthesize deoxyribonucleotides. The 2'-deoxynucleoside-5'-triphosphate mixture is purified and modified to produce high purity products for research purposes. These compounds have novel properties, making them suitable for creating new drugs with improved efficacy and reduced side effects.</p>Pureza:Min. 95%6-Methylmercapto-9-(b-D-ribofuranosyl)purine
CAS:<p>6-Methylmercapto-9-(b-D-ribofuranosyl)purine (6MMPR) is a nucleotide analog that is synthesized through the process of ribosylation. It has been shown to be reactive and inflammatory in the colon, which may be due to its role as an enzyme inhibitor. 6MMPR inhibits target enzymes such as 2-methylthio-6-chloropurine riboside, which are involved in DNA synthesis and repair. This drug also has anti-inflammatory properties, which may be due to its ability to inhibit the production of inflammatory cytokines by activated immune cells. 6MMPR is used for the treatment of bowel diseases such as Crohn's disease and ulcerative colitis.</p>Fórmula:C11H14N4O4SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:298.32 g/mol3-Iodo-1-(2-C-methyl-b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine,
CAS:<p>3-Iodo-1-(2-C-methyl-b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a novel antiviral monophosphate nucleotide analog. It has been shown to be an effective activator of the enzyme ribonucleotide reductase, which is involved in DNA synthesis and repair. 3Iodo possesses anticancer activity, inhibiting the proliferation of cancer cells by interfering with DNA synthesis. The compound also inhibits tumor cell growth in vivo by inducing apoptosis. 3Iodo has been shown to inhibit HIV replication and may have potential as a treatment for HIV/AIDS.</p>Pureza:Min. 95%2'-Deoxy-5-formylcytidine
CAS:<p>2'-Deoxy-5-formylcytidine is a nucleoside analog that is used as a chemotherapeutic agent. It is cytotoxic to cells by binding to DNA and preventing the synthesis of DNA, RNA, and protein. The drug has been shown to induce cellular senescence in human fibroblasts, which can be reversed by the addition of deuterium. 2'-Deoxy-5-formylcytidine also inhibits the production of reactive oxygen species (ROS) by inducing the expression of antioxidant enzymes such as superoxide dismutase 2 and glutathione peroxidase 1. The oxidation products are misincorporated into DNA strands, leading to intramolecular hydrogen bonds with cytosine bases. These modifications lead to denaturation of DNA and inhibition of transcription and replication.<br>2'-Deoxy-5-formylcytidine also interacts with oligodeoxynucleotides, which leads to misinc</p>Fórmula:C10H13N3O5Pureza:Min. 97 Area-%Cor e Forma:White PowderPeso molecular:255.23 g/mol2’-Deoxy-5’-O-DMT-N2-isobutyrylguanosine-3’-(4-nitrophenoxyl)butanedioate
<p>2’-Deoxy-5’-O-DMT-N2-isobutyrylguanosine-3’-(4-nitrophenoxyl)butanedioate is a novel antiviral drug that has been synthesized by coupling diphosphate and monophosphate nucleosides to an antiviral agent. The synthesis of this product is done through the use of activated 2,4,6,-trichlorobenzoyl chloride as a coupling agent. This product can be used in the treatment of cancer cells.</p>Pureza:Min. 95%1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)6-methylpurine
CAS:<p>1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)6-methylpurine is a synthetic nucleoside analog that has been shown to be an activator of DNA synthesis in mammalian cells. It has antiviral, anticancer, and antibiotic properties due to its ability to inhibit the growth of a variety of cancer cells. 1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)6-methylpurine also inhibits viral replication by interfering with the replication machinery. This nucleoside analog is a modified form of 6MP and has high purity and quality.</p>Pureza:Min. 95%2-Deoxy-2-Fluoro-a-D-arabinofuranosylamine
CAS:<p>2-Deoxy-2-Fluoro-a-D-arabinofuranosylamine is a novel antiviral agent that is synthesized from 2,4,6-trichlorobenzoyl chloride and 2,4,6-trifluorophenylglycine. It has been shown to be effective in inhibiting the replication of HIV and HSV types 1 and 2. This compound also has anticancer activity against colorectal cancer cells. The synthesis of this compound results in high purity with a high yield.</p>Fórmula:C5H10FNO3Pureza:Min. 95%Peso molecular:151.14 g/mol3’-b-Azido-2’,3’-dideoxy-5’-O-(4-methoxytrityl)uridine
CAS:<p>3’-b-Azido-2’,3’-dideoxy-5’-O-(4-methoxytrityl)uridine (AZDU) is a modified nucleoside that is used as an antiviral agent. AZDU inhibits viral DNA synthesis by acting as a competitive inhibitor of the enzyme ribonucleotide reductase. AZDU has also been shown to inhibit tumor cell growth in vitro and in vivo. In addition, AZDU has been found to have anticancer activity against human leukemia cells, which may be due to its ability to inhibit DNA synthesis.</p>Pureza:Min. 95%2-Methylthioadenosine
CAS:<p>2-Methylthioadenosine is a purine nucleoside which induces necrotic cell death. It is the first of its kind to be shown to have activity against squamous carcinoma cells, and is activated by nucleoside phosphorylase in order to produce its cytotoxic form. 2-Methylthioadenosine also inhibits the transcription-polymerase chain reaction and increases oxidative injury. This drug has been shown to have receptor activity in brain cells, as well as chemotactic activity for gland cells. 2-Methylthioadenosine has been used as a model organism for polymerase chain reactions, and has been shown to inhibit p2y receptors in the human colon cancer cell line HT29.</p>Fórmula:C11H15N5O4SPureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:313.34 g/mol6-Benzyl-2-thiouracil
CAS:<p>6-Benzyl-2-thiouracil (BTS) is a benzyl group with the chemical formula C12H8N2OS. It has been used as an anti-infective agent and has been shown to have a clinical relevance in treating hepatitis, cutaneous lesions, and inflammatory bowel disease. BTS is metabolized through oxidation of the benzyl group by cytochrome P450 enzymes. This active form has been shown to inhibit mitochondrial fatty acid synthesis, which may be a pathogenic mechanism for BTS in women with metabolic syndrome. The metabolism of BTS also results in its conversion to 2-benzylpyrimidine, which can be converted into a carcinogen by N-nitrosation.</p>Fórmula:C11H10N2OSPureza:Min. 95%Cor e Forma:PowderPeso molecular:218.28 g/mol2,3'-Anhydro-5'-O-tert-butyldimethylsilyl-N4-benzoyl-2'-deoxycytidine
CAS:<p>2,3'-Anhydro-5'-O-tert-butyldimethylsilyl-N4-benzoyl-2'-deoxycytidine is an antiviral agent that is a synthetic nucleoside analogue. It acts as an activator of monophosphate and as a DNA phosphoramidite. 2,3'-Anhydro-5'-O-tert-butyldimethylsilyl-N4-benzoyl-2'-deoxycytidine has been shown to inhibit the growth of cancer cells and is being studied for its anticancer activity. This drug also inhibits ribonucleotide reductase, which prevents the conversion of ribonucleotides to deoxyribonucleotides, thereby inhibiting DNA synthesis.</p>Fórmula:C22H31N3O4SiPureza:Min. 95%Peso molecular:429.6 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
CAS:<p>N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is a novel nucleoside and deoxyribonucleoside that has been synthesized by the chemical modification of cytidine. It is an anticancer drug and antiviral agent, which has been shown to activate DNA polymerase, inhibit RNA synthesis and have antiviral activities against HIV, HSV, CMV, and VZV. N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite has high purity with low impurities (0.1% DMSO), making it a valuable nucleoside for use in synthesis of ribonucleotide analogues.</p>Fórmula:C42H52N5O8PPureza:Min. 97 Area-%Cor e Forma:White Off-White PowderPeso molecular:785.86 g/mol1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)-5-ethyluracil
CAS:<p>1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)-5-ethyluracil is a nucleoside analog with modifications to alter its biological activity. It contains a β-D-arabinofuranose sugar instead of the standard β-D-deoxyribose in natural nucleosides and<br>the fluorine (F) at the 2'-position increases resistance to enzymatic degradation and alters its biological activity. The 5-ethyl modification on the uracil ring enhances its interaction with viral polymerases.</p>Fórmula:C11H15FN2O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:274.25 g/mol5-(2',3',5'-Tri-O-benzyl-b-D-ribofuranosyl)-3-methyl-2-benzyloxypyridine
CAS:<p>5-(2',3',5'-Tri-O-benzyl-b-D-ribofuranosyl)-3-methyl-2-benzyloxypyridine is a nucleoside analog that inhibits the growth of cancer cells. This compound has been shown to inhibit the synthesis of deoxyribonucleosides and ribonucleosides, and also inhibit the growth of certain viruses. 5-(2',3',5'-Tri-O-benzyl-b-D-ribofuranosyl)-3 methyl -2 benzyloxypyridine can be used as a phosphoramidite or activator in the synthesis of DNA or RNA.</p>Pureza:Min. 95%
