Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3570 produtos de "Nucleosídeos"
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1,N6-Ethenoadenosine-5'-diphosphate, Sodium salt
CAS:Emission max - 415nmMolar extinction coefficient ε [L·mol⁻¹·cm⁻¹] - 6000Fluorescent analogue of 5'-ADP, NA10698Fórmula:C12H15N5O10P2Pureza:Min. 95%Peso molecular:451.22 g/mol6-Amino-9-(1-deoxy-b-D-psicofuranosyl)purine
CAS:6-Amino-9-(1-deoxy-β-D-psicofuranosyl)purine (6APdP) is a nucleoside with potential chemotherapeutic activity. It has been shown to suppress the expression of genes that encode proteins involved in cell proliferation and differentiation, including suppressor genes. 6APdP is activated by methyladenosine monophosphate kinase and binds to the ribose hydroxyl group on RNA molecules. This molecule has been shown to inhibit hepatitis B virus replication and cancer cell growth in animal models. The hydrogen bonding interactions between 6APdP and the ribose hydroxyl group are stronger than those associated with ethylene diamine tetraacetic acid (EDTA). 6APdP is also an inhibitor of protein synthesis.Fórmula:C11H15N5O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:281.27 g/molDiquafosol Impurity 2
CAS:Diquafosol Impurity 2 is a high-purity phosphoramidite that can be used for the synthesis of DNA, RNA, and deoxyribonucleosides. This product is also a novel activator for phosphoramidites. Diquafosol Impurity 2 has CAS No. 63785-59-1 and a molecular weight of 228.24 g/mol. It is insoluble in water, but soluble in most organic solvents.
Fórmula:C18H25N4O20P3Pureza:Min. 95%Peso molecular:710.33 g/mol2-Amino-8-bromo-9-(b-D-ribofuranosyl)purine
CAS:2-Amino-8-bromo-9-(b-D-ribofuranosyl)purine is a modified nucleoside that inhibits viral DNA and RNA synthesis. It has antiviral properties against influenza, herpes simplex virus type 1, hepatitis B virus, and human immunodeficiency virus type 1. 2-Amino-8-bromo-9-(b-D-ribofuranosyl)purine has been shown to be effective in the treatment of cancers such as leukemia, lymphoma, and breast cancer. This drug is a novel nucleoside analogue that is used for cancer chemotherapy. 2-Amino 8 bromo 9 (b D ribofuranosyl) purine is not active against bacteria or fungi.Fórmula:C10H12BrN5O4Pureza:Min. 95%Peso molecular:346.14 g/molBiotin-5-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution
Biotin-5-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution is a modified nucleoside with antiviral activity. It is a phosphoramidite that can be used for the synthesis of DNA, RNA and other nucleic acids. Biotin-5-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution is an active ingredient in many research laboratories.Fórmula:C22H35N6O15P3SPureza:Min. 95%Peso molecular:748.53 g/mol3-Deazauridine-5'-triphosphate triethylamine salt
CAS:3-Deazauridine-5'-triphosphate triethylamine salt is a xanthosine analog that has been used as a biochemical reagent in animals and humans. It is postulated to be a potential cancer therapeutic agent because of its ability to inhibit DNA synthesis and cell division. 3-Deazauridine-5'-triphosphate triethylamine salt inhibits the biosynthesis of uridine in leukemic mice, hamster V79 cells, and mammalian cells. This drug inhibits the incorporation of uracil into RNA by competitive inhibition with respect to ATP. 3DATTP also inhibits the incorporation of thymidine into DNA by competitive inhibition with respect to dCTP.Fórmula:C10H16NO15P3Pureza:Min. 95%Peso molecular:483.15 g/mol8-Bromo-5'-o-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine
CAS:8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine (8-Bromo-5'-O-(DMT)-dG) is a novel nucleoside that is synthesized by reacting 8-bromo-5'-O-(dimethyoxytrityl)-2'-deoxyguanosine with dimethylaminomethylidene. It has antiviral, anticancer, and ribonucleoside activities. 8-Bromo-5'-O-(DMT)-dG is used as a building block for the synthesis of oligonucleotides, phosphoramidites, and other modified nucleosides. 8-Bromo-5'-O-(DMT)-dG is currently being developed as an anticancer drug.Fórmula:C34H35BrN6O6Pureza:Min. 95%Peso molecular:703.6 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine
CAS:2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is a modified nucleoside that is used to synthesize oligonucleotides. It is a phosphoramidite, and can be used in the synthesis of DNA or RNA. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is an antiviral agent that has been shown to have anticancer activity in animal models. It has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) and serum enzymes, such as dismutase activity, in mice with lung cancer. This drug also has a toxic effect on respiratory system cells, which may be due to its ability to induce apoptosis.
Pureza:Min. 95%1-(5-o-(Dimethoxytrityl)-β-D-2-deoxyribofuranosyl)-3-nitropyrrole
CAS:1-(5-O-(dimethoxytrityl)-β-D-2-deoxyribofuranosyl)-3-nitropyrrole is a novel nucleoside phosphoramidite that has been modified to include an oxazole moiety. It is an antiviral and anticancer drug that inhibits the replication of DNA by binding to the enzyme DNA polymerase. 1-(5-O-(dimethoxytrityl)-β-D-2-deoxyribofuranosyl)-3-nitropyrrole is also a substrate for monophosphate, diphosphate, and triphosphate nucleotide kinases, which are enzymes that catalyze the phosphorylation of 5'-monophosphates. This nucleoside phosphoramidite can be used in the synthesis of oligonucleotides and modified oligonucleotides.Fórmula:C30H30N2O7Pureza:Min. 95%Peso molecular:530.6 g/mol5'-Fluoro-5'-deoxy-adenosine
CAS:5'-Fluoro-5'-deoxy-adenosine (FDA) is a fluorinated adenosine derivative that has been shown to regulate glucose levels in plasma. It has been shown to increase the uptake of glucose in cells and improve insulin sensitivity, which may be due to its ability to increase the production of nitric oxide. FDA is also thought to act as an antioxidant and may be useful for treating autoimmune diseases such as insulin resistance and type II diabetes.Fórmula:C10H12FN5O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:269.23 g/mol5'-Hydrazino-5'-deoxyguanosine
CAS:5'-Hydrazino-5'-deoxyguanosine is a novel diphosphate nucleoside analog that has been shown to be an efficient activator of the anti-cancer enzyme ribonucleotide reductase. It is synthesized by reacting 5'-hydrazinouridine with hydroxylamine and then coupling with 5'-deoxyguanosine. The resulting product has been shown to inhibit DNA synthesis in vitro and in vivo, as well as to produce cytotoxic effects in human cancer cells. This compound also inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or
Fórmula:C10H15N7O4Pureza:Min. 95%Peso molecular:297.27 g/mol3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine
3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine is a novel nucleoside analogue with high purity and quality. It is a DNA activator that has been shown to be active against both RNA and DNA viruses. 3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine phosphorylates to the corresponding monophosphate, which inhibits viral DNA synthesis by competitive inhibition of diphosphate formation. This compound has also been shown to be an effective inhibitor of HIV replication in vitro.Fórmula:C24H20N8O4Pureza:Min. 95%Peso molecular:484.47 g/mol2',3',5'-Tri-O-(p-chlorobenzoyl)-5-azacytidine
CAS:2',3',5'-Tri-O-(p-chlorobenzoyl)-5-azacytidine is a novel nucleoside phosphoramidite for the synthesis of DNA and RNA. It has been modified to be resistant to antiviral and anticancer agents, as well as to be an activator of monophosphate. 2',3',5'-Tri-O-(p-chlorobenzoyl)-5-azacytidine has high purity and quality, as well as being novel and modified.Fórmula:C29H21Cl3N4O8Pureza:Min. 95%Peso molecular:659.86 g/mol2'-Deoxy-5'-DMT-5-ethynyluridine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-DMT-5-ethynyluridine 3'-CE phosphoramidite is a nucleoside that is used as an activator for DNA synthesis. It has been shown to be effective against viruses such as HIV and herpes simplex virus. This compound also has anticancer properties. 2'-Deoxy-5'-DMT-5-ethynyluridine 3'-CE phosphoramidite binds to the viral RNA or DNA, displacing the natural phosphate group on the 5' end of the viral chain and preventing viral replication.Fórmula:C41H47H40O8Pureza:Min. 95%Peso molecular:708.12 g/molThymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt
CAS:Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt is a nucleoside that is a synthetic analog of thymidine. It has antiviral activity and is used in the synthesis of DNA and RNA. This product has shown to be effective against HIV, influenza, polio, herpes, and human papillomavirus. Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt can also be used for the synthesis of phosphoramidites for oligonucleotide synthesis.Fórmula:C20H26N7O10P·NH3Pureza:Min. 95%Peso molecular:572.47 g/molN6-Methyl-2'-O-methyladenosine 5'-monophosphate
N6-Methyl-2'-O-methyladenosine 5'-monophosphate (N6-MMAMP) is a nucleoside analogue that is used as an anticancer and antiviral agent. N6-MMAMP is a modified nucleoside that has been shown to be effective in the treatment of some cancers, such as leukemia. It also has antiviral properties and can be used to inhibit the replication of viruses such as human immunodeficiency virus type 1 (HIV). N6-MMAMP has been shown to have high purity and quality, making it an excellent choice for research purposes.Pureza:Min. 95%7-Deaza-2'-deoxy-5'-O-DMT-N2-isobutyrylguanosine
7-Deaza-2'-deoxy-5'-O-DMT-N2-isobutyrylguanosine is an activator that has been shown to stimulate the production of DNA and RNA. This compound is a novel synthetic nucleoside with high purity and quality. 7-Deaza-2'-deoxy-5'-O-DMT-N2-isobutyrylguanosine is effective against viruses and cancer cells by inhibiting viral protein synthesis and by stimulating the immune system. This drug has also been shown to be an anticancer agent, which may be due to its ability to inhibit cell division, induce apoptosis, or inhibit cellular proliferation.Fórmula:C36H38N4O7Pureza:Min. 95%Peso molecular:638.73 g/mol(-)-Adenosine 3'-monophosphate hydrate
CAS:Adenosine 3'-monophosphate hydrate is a nucleoside that is an important intermediate in the biosynthesis of DNA and RNA. It is a phosphodiesterase inhibitor, which prevents the breakdown of adenosine 3'-monophosphate (cAMP). This compound also has a role in various other metabolic pathways, such as the synthesis of purines. Adenosine 3'-monophosphate hydrate is used for preparing adenosylcobalamin and for studies on phosphodiesterases. The nature of this compound is determined by its chemical structure, including functional groups and sequences. Its modification includes the addition of phosphate groups to its ribose sugar moiety. Adenosine 3'-monophosphate hydrate has a molecular weight of 372.4 g/mol and optimum pH of 7-8.
The hybridization behavior and ph optimum are characteristic properties of this compound.Fórmula:C10H16N5O8PPureza:Min. 95%Peso molecular:365.24 g/mol5-Bromo-2'-deoxyuridine-5'-triphosphate sodium salt
CAS:5-Bromo-2'-deoxyuridine-5'-triphosphate sodium salt is a modified nucleoside with antiviral properties. This drug inhibits the polymerase activity of reverse transcriptase and thus prevents the synthesis of DNA from RNA. 5-Bromo-2'-deoxyuridine-5'-triphosphate sodium salt has been shown to be effective against herpes viruses, influenza virus, and cytomegalovirus. This drug also prevents the replication of HIV.Fórmula:C9H14N2O14P3BrPureza:Min. 95%Peso molecular:547.04 g/molBiotin-11-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution
CAS:Biotin-11-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution is an antiviral nucleoside that has been shown to inhibit HIV and HCV replication in vitro. It also inhibits the proliferation of cancer cells in vitro and induces apoptosis in vivo. Biotin-11-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution is a novel nucleoside that was designed for use as an anticancer agent. The compound can be used to modify DNA or RNA molecules at the ribonucleotide or deoxyribonucleotide level.Fórmula:C28H46N7O16P3SPureza:Min. 95%Peso molecular:861.69 g/mol
