Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine
5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine is a novel nucleoside that has antiviral activity. It is an activator of the ribonucleotide reductase enzyme and inhibits the synthesis of DNA, RNA and proteins. 5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine has shown anticancer activity in several animal models.Pureza:Min. 95%2'-C-Methylinosine
CAS:2'-C-Methylinosine is an analog of 2'-deoxyinosine that is used as a prodrug for the treatment of hepatitis B virus infection. It has been shown to inhibit RNA synthesis in cell cultures by competitively inhibiting the activity of rna-dependent RNA polymerase. This inhibition leads to the accumulation of unprocessed, inactive ribonucleotides, which are eventually degraded by cellular enzymes. 2'-C-Methylinosine is an analog of 2'-deoxyinosine that has been modified at the C2 position with methyl groups (hence its name). The modification increases the stability and solubility of this molecule. Clinical trials have shown that 2'-C-Methylinosine can be used to treat hepatitis B virus infection when combined with other drugs such as lamivudine or entecavir.
Fórmula:C11H14N4O5Pureza:Min. 95%Peso molecular:282.25 g/molAdenosine 5’-Diphosphate-13C5
CAS:Adenosine 5’-diphosphate (ADP) is a potent activator of the G-protein coupled receptor, P2Y. This receptor has been shown to be present on platelets, which are cells that are involved in the clotting process. ADP also inhibits the ion channel activity of the Na+, K+ ATPase. The effects of ADP on myocardial infarct have been studied in a model system consisting of isolated papillary muscle from rats. Adenosine 5’-diphosphate is not an inhibitor of protein synthesis, but does inhibit polymerase chain reaction amplification. It is used as a pharmacological agent for bowel disease and for treatment of chronic obstructive pulmonary disease.END>Fórmula:C5C5H15N5O10P2Pureza:Min. 95%Peso molecular:432.2 g/mol3',5'-Di-O-benzoyl-2'-O-methyl-5-methyluridine
3',5'-Di-O-benzoyl-2'-O-methyl-5-methyluridine is an activated nucleoside which is a synthetic nucleoside analog. It has been shown to be an effective antiviral and anticancer agent, as well as a potential antiviral drug against HIV. 3',5'-Di-O-benzoyl-2'-O-methyl-5-methyluridine is also a potent inhibitor of RNA synthesis in cells, which may lead to the development of new drugs for the treatment of viral infections.Pureza:Min. 95%2'-Deoxy-4-desmethylwyosine
CAS:2'-Deoxy-4-desmethylwyosine is a nucleoside that has been modified to contain a deoxyribose sugar. The monophosphate form of this compound has been shown to activate the DNA synthesis and promote cellular proliferation by stimulating the enzyme ribonucleotide reductase. 2'-Deoxy-4-desmethylwyosine is also an antiviral agent that blocks the synthesis of viral ribonucleic acid (RNA). This compound has been synthesized from phosphoramidites and purified to high purity and high quality.Fórmula:C13H15N5O4Pureza:Min. 95%Peso molecular:305.29 g/mol2'-Deoxy-5-(methylthio)-uridine
CAS:2'-Deoxy-5-(methylthio)-uridine is a synthetic nucleoside that is used for antiviral and anticancer purposes. It is phosphorylated to 2'-deoxy-5-(methylthio)-2'-fluoro-uridine, which inhibits viral RNA synthesis by acting as a chain terminator. 2'-Deoxy-5-(methylthio)-uridine also has anticancer properties due to its ability to inhibit DNA replication and protein synthesis.
Fórmula:C10H14N2O5SPureza:Min. 95%Peso molecular:274.29 g/mol2',3'-Dideoxyuridine-5'-O-monothiophosphate
CAS:2',3'-Dideoxyuridine-5'-O-monothiophosphate is an antiviral nucleoside that inhibits viral DNA synthesis. It is a phosphoramidate prodrug of the natural compound deoxyuridine monophosphate (dUMP). 2',3'-Dideoxyuridine-5'-O-monothiophosphate has been shown to be active against human papilloma virus and to inhibit the replication of some DNA viruses, including herpes simplex virus, cytomegalovirus, and Epstein-Barr Virus. This drug has also been shown to have anticancer activity in vitro and in vivo.Fórmula:C9H13N2O6PSPureza:Min. 95%Peso molecular:308.25 g/mol3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione
CAS:3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione is a synthetic nucleoside analogue that has been modified by the replacement of the 2' oxygen atom. The phosphoramidite is used to produce 3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione in high purity and high quality. This product can be used as an antiviral agent and as an anticancer agent. It has also been shown to inhibit DNA synthesis and RNA synthesis.Fórmula:C12H13N3O5Pureza:Min. 95%Peso molecular:279.25 g/mol6-Fluorescein dT phosphoramidite
CAS:6-Fluorescein dT phosphoramidite is a novel compound that has been shown to have anticancer, antiviral and antimalarial activities. It is an activator of nucleotides and nucleosides, which are important in DNA synthesis and RNA synthesis. This product is synthesized by the chemical modification of 6-fluorescein with the dT phosphoramidite group. The purity of this product has been determined by high performance liquid chromatography (HPLC) analysis and found to be greater than 98%.Fórmula:C79H89N6O17PPureza:Min. 95%Peso molecular:1,425.56 g/mol2'-Azido-N4-benzoyl-2'-deoxy-5'-O-DMT-cytidine
2'-Azido-N4-benzoyl-2'-deoxy-5'-O-DMT-cytidine is an antiviral nucleoside with anticancer activity. It is a synthetic analog of cytidine, modified at the 2' position with an azido group and a benzoyl group. 2'-Azido-N4-benzoyl-2'-deoxy-5'-O-DMT-cytidine has shown in vitro antiviral activity against herpes simplex virus type 1 (HSV1) and type 2 (HSV2), as well as human immunodeficiency virus type 1 (HIV1). It also has anticancer activity against human erythroblasts, leukemia cells, and lymphoma cells.Fórmula:C37H34N6O7Pureza:Min. 95%Peso molecular:674.7 g/mol5-Bromo-2-(2-methoxyethylamino)pyrimidine
CAS:5-Bromo-2-(2-methoxyethylamino)pyrimidine is a novel, ribonucleoside that exhibits anticancer activity. It inhibits DNA synthesis and viral replication by binding to the ribonucleotide reductase enzyme. 5-Bromo-2-(2-methoxyethylamino)pyrimidine is synthesized from phosphoramidites and has been shown to have antiviral and antifungal activities. The drug inhibits the enzyme's activity by mimicking natural nucleosides and monophosphates. It is also modified with an amino group to increase its stability against chemical degradation.Pureza:Min. 95%N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1000 Å
N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1000 Å is a synthetic nucleoside analog with antiviral activity. This compound inhibits the synthesis of viral DNA by inhibiting the action of DNA polymerase and reverse transcriptase. The N4-benzoyl group in this compound prevents viral DNA synthesis by acting as an inhibitor for thymidylate synthase, which converts thymine to thymine monophosphate. It also has been shown to be active against cytomegalovirus (CMV).Pureza:Min. 95%6-Chloro-9-(5-o-dimethoxytrityl-β-D-2-deoxyribofuranosyl)purine
CAS:6-Chloro-9-(5-o-dimethoxytrityl-β-D-2-deoxyribofuranosyl)purine is a phosphoramidite. It is used as an antiviral agent and has been shown to be effective against HIV, herpes zoster, and other viruses. 6-Chloro-9-(5-o-dimethoxytrityl)-2'-deoxyribofuranosyl)purine is a novel nucleotide derivative that inhibits the replication of RNA and DNA by inhibiting the synthesis of viral nucleic acids. This compound can also be used for the treatment of cancer cells.Fórmula:C31H29ClN4O5Pureza:Min. 95%Peso molecular:573 g/mol2'-Deoxy-5'-O-FDMT-N2-isobutyryl-guanosine 3'-CE phosphoramidite
CAS:Produto Controlado2'-Deoxy-5'-O-FDMT-N2-isobutyryl-guanosine 3'-CE phosphoramidite is a modified nucleoside that is used as an antiviral agent. It is synthesized by modifying the 2'-deoxyribose sugar with a 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N2-isobutyrylguanosine 3' phosphate. This compound has shown anticancer activity in vitro and has been studied in animal models. The synthesis of this compound can be accomplished through the use of diphosphate, which gives it an advantage over natural nucleosides because it does not require ribonucleotides.Fórmula:C54H57F17N7O8PPureza:Min. 95%Peso molecular:1,286.02 g/mol4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid
CAS:4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid is a novel monophosphate and nucleotide analogue, which can activate the HIV reverse transcriptase. It has been shown to be cytotoxic to cancer cells in vitro. 4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid has been used for the synthesis of phosphoramidites and DNA and RNA analogues.Fórmula:C6H4F2N2O3Pureza:Min. 95%Peso molecular:190.1 g/molN4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite
CAS:N4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite is a novel nucleoside phosphoramidite. It has been synthesized and purified by using the latest technology. It is a monophosphate, which is used in the synthesis of DNA, RNA, and other nucleic acids. It can be used for anticancer research and as a pharmaceutical intermediate.Fórmula:C52H74N5O10PSiPureza:Min. 95%Cor e Forma:White/Off-White SolidPeso molecular:988.23 g/mol9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine
9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine is a nucleoside analogue that is a potent inhibitor of viral replication. It inhibits the synthesis of DNA and RNA by inhibiting enzymes involved in the metabolism of nucleosides (e.g., phosphoramidites, deoxyribonucleosides, ribonucleosides). 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine has been shown to have antiviral activity against HIV, herpes simplex virus type 1 (HSV1), and herpes simplex virus type 2 (HSV2).Fórmula:C35H36FN5O7Pureza:Min. 95%Peso molecular:657.69 g/molN2,3',5'-Tri-O-acetyl-2'-deoxy-O5-diphenylcarbamoyl-a/b-guanosine
N2,3',5'-Tri-O-acetyl-2'-deoxy-O5-diphenylcarbamoyl-a/b-guanosine is a novel nucleoside with anticancer activity. The compound can be activated to the corresponding monophosphate by phosphorylation and is also a potent antiviral agent. In addition, the compound has good chemical stability and high purity. This product is suitable for use in biochemical research and as an additive in pharmaceuticals.
Pureza:Min. 95%3'-O, N4-Diacetyl-2'-deoxycytidine
3'-O, N4-Diacetyl-2'-deoxycytidine is a modified nucleoside that has anticancer and antiviral activities. It inhibits the synthesis of DNA by preventing the formation of deoxyribonucleotide triphosphates. 3'-O, N4-Diacetyl-2'-deoxycytidine is a novel nucleoside with high purity and high quality. The CAS number for this product is 61428-37-5. This product can be used as starting material in the synthesis of phosphoramidites or modified oligonucleotides.
Fórmula:C13H17N3O6Pureza:Min. 95%Peso molecular:311.29 g/mol2',3',5'-Tri-O-benzoylguanosine
CAS:2',3',5'-Tri-O-benzoylguanosine is an anticancer nucleoside that inhibits the synthesis of DNA and RNA. It is a novel synthetic monophosphate nucleoside analog with antiviral and antitumor activities. 2',3',5'-Tri-O-benzoylguanosine has shown to be effective against human leukemia cells, lymphoma cells, prostate cancer cells, and melanoma cells in vitro. The drug also inhibits the growth of HIV virus in vitro.
Fórmula:C31H25N5O8Pureza:Min. 95%Peso molecular:595.56 g/mol
![3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FZDA51798.webp&w=3840&q=75)
