Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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2,2'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine
2,2'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine is a novel monophosphate nucleoside analog that has antiviral activity against herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2). This compound is chemically synthesized by the reaction between thymidine with bis-(2,6-diisopropylphenyl) disilazane in the presence of an activator. The synthesis of 2,2'-anhydro-5'-O-tert-butyldiphenylsilylthymidine is performed by reacting 5'-O-(4,4'-dimethoxytrityl)-thymidine with bis-(2,6-diisopropylphenyl) disilazane in the presence of tetrakis(triphenylphosphine)palladium(0Pureza:Min. 95%7-Deaza-2'-C-methylguanosine
CAS:7-Deaza-2'-C-methylguanosine is a nucleoside that is obtained from the synthesis of 7-deazaguanosine. It has antiviral activity and has been shown to be an activator for DNA synthesis. This compound is used as a monophosphate, diphosphate, or phosphoramidite in the synthesis of oligonucleotides. 7-Deaza-2'-C-methylguanosine has been shown to have anticancer properties, which may be due to its ability to inhibit ribonucleotide reductase and thus inhibit DNA synthesis.Fórmula:C12H16N4O5Pureza:Min. 95%Peso molecular:296.29 g/mol5'-O-DMT-N4-benzoyl-5-methyl-(2'-O-4'-C-methylene)-cytidine 3'-CE phosphoramidite
5'-O-DMT-N4-benzoyl-5-methyl-(2'-O-4'-C-methylene)-cytidine 3'-CE phosphoramidite is a novel nucleoside analogue that has antiviral, anticancer and antimalarial activity. It is also used as a building block for the synthesis of oligonucleotides and in the modification of DNA, RNA and proteins. 5'-O-DMT-N4-benzoyl-5-methyl-(2'-O-4'-C-methylene)-cytidine 3'-CE phosphoramidite is an analogue of cytidine, which can be incorporated into DNA by means of enzymatic reactions. In addition to its antiviral, anticancer and antimalarial properties, it has been shown to have antiinflammatory effects. This drug is synthesized by chemical modification of cytosine, with 2′-, 4′-, or 6′ -Pureza:Min. 95%3',5'-Di-O-acetyl-N4-acetyl-2'-deoxycytidine
3',5'-Di-O-acetyl-N4-acetyl-2'-deoxycytidine is a synthetic nucleoside. It is an activator of the immune system and has antiviral activities. 3',5'-Di-O-acetyl-N4-acetyl-2'-deoxycytidine is also a potent inhibitor of DNA and RNA polymerases, thereby preventing the synthesis of these nucleic acids. This drug has been shown to inhibit tumor cell growth in cultures of human cancer cells and has been used as a potential anticancer agent in clinical trials. The drug's activity as an immunomodulator is due to its ability to bind to lymphocytes, which leads to the production of cytokines that stimulate the immune system. 3',5'-Di-O-acetyl-N4-acetyl-2'-deoxycytidine also inhibits HIV replication by binding to viral reverse transcriptase and preventing it from copying the viral genomeFórmula:C15H19N3O7Pureza:Min. 95%Peso molecular:353.33 g/molN6-Methyladenosine-5'-triphosphate sodium salt - 10 mM aqueous solution
CAS:Modulator of P2Y receptors
Fórmula:C11H18N5O13P3Pureza:Min. 95%Peso molecular:521.21 g/mol5'-Iodo-2',3'-dideoxycytidine
5'-Iodo-2',3'-dideoxycytidine is a nucleoside analog that is used as an antiviral agent and an anticancer drug. It inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase, which is necessary for DNA replication. This compound also has a high quality and purity, as it is synthesized in a controlled environment. 5'-Iodo-2',3'-dideoxycytidine has shown to be effective against leukemia cells in culture and has been shown to inhibit the growth of cancer cells in animal models. 5'-Iodo-2',3'-dideoxycytidine has shown to be effective against leukemia cells in culture and has been shown to inhibit the growth of cancer cells in animal models.Fórmula:C9H12N3O3IPureza:Min. 95%Peso molecular:337.11 g/molL-Adenosine 5'-triphosphate sodium salt
CAS:L-Adenosine 5'-triphosphate sodium salt is a monophosphate, diphosphate, and triphosphate analog of adenosine that is used as an antiviral agent. L-Adenosine 5'-triphosphate sodium salt is a synthetic nucleoside that is modified at the ribose sugar to form a phosphoramidite. This modification increases the stability of the molecule and prevents hydrolysis by ribonucleases. L-Adenosine 5'-triphosphate sodium salt is also known as Ado-5'-P or ATPγS.Fórmula:C10H12N5O13P3Na4Pureza:Min. 95%Peso molecular:595.11 g/molN4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite
CAS:N4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite is a novel nucleoside phosphoramidite. It has been synthesized and purified by using the latest technology. It is a monophosphate, which is used in the synthesis of DNA, RNA, and other nucleic acids. It can be used for anticancer research and as a pharmaceutical intermediate.Fórmula:C52H74N5O10PSiPureza:Min. 95%Cor e Forma:White/Off-White SolidPeso molecular:988.23 g/mol2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine
CAS:2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine (ABT-888) is a nucleoside analog that inhibits DNA synthesis and RNA transcription. It has been shown to induce apoptosis in human cancer cells, including leukemia, lymphoma and breast cancer cells. ABT-888 also has antiviral activity against herpes simplex virus type 1 and 2, vaccinia virus, and vesicular stomatitis virus.Fórmula:C19H20N2O7Pureza:Min. 95%Peso molecular:388.37 g/mol5-Aminoallyl-2'-deoxyuridine
CAS:5-Aminoallyl-2'-deoxyuridine is a bifunctional alkylating agent that has low affinity for DNA. It is used in the laboratory to measure the rate of synthesis of thymidylate, which is one of the four deoxythymidylate needed for DNA synthesis. 5-Aminoallyl-2'-deoxyuridine has been shown to be a stable complex with sulfoxide, which can be used as an alkylation agent in the laboratory. 5-Aminoallyl-2'-deoxyuridine has also been shown to have high affinity for cellular nucleic acids in l1210 cells and have a high uptake. The sequence of 5-aminoallyl-2'-deoxyuridine is: 5-(N-(2-(5-aminoallylamino)ethyl)-N-(carboxyethyl)glycine)-2',3',5'-triiod
Fórmula:C12H18N4O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:282.3 g/mol2'-Deoxy-5'-O-FDMT-N2-isobutyryl-guanosine 3'-CE phosphoramidite
CAS:Produto Controlado2'-Deoxy-5'-O-FDMT-N2-isobutyryl-guanosine 3'-CE phosphoramidite is a modified nucleoside that is used as an antiviral agent. It is synthesized by modifying the 2'-deoxyribose sugar with a 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N2-isobutyrylguanosine 3' phosphate. This compound has shown anticancer activity in vitro and has been studied in animal models. The synthesis of this compound can be accomplished through the use of diphosphate, which gives it an advantage over natural nucleosides because it does not require ribonucleotides.Fórmula:C54H57F17N7O8PPureza:Min. 95%Peso molecular:1,286.02 g/mol8-Methoxyadenosine
CAS:8-Methoxyadenosine is an acidic adenosine that acts as a competitive antagonist of the A1 receptor. It has a high affinity for this receptor and blocks the binding of adenosine to the receptor, thereby inhibiting its function. 8-Methoxyadenosine is also a competitive antagonist of the uridine nucleotide, which inhibits enzymatic catalysis by ribonucleoside kinase and ribonucleotide reductase. It has been shown to have properties similar to those of other pyrimidine nucleosides such as cytidine, thymine, and uridine. This molecule has a hydroxyl group in its structure, which is essential for binding to these enzymes. 8-Methoxyadenosine also has a phosphate group in its structure, which is necessary for the synthesis of DNA or RNA from deoxyribonucleotides. The benzoate group in 8-methoxyadenosine's structure makesPureza:Min. 95%3’-Deoxy- 3'- methylguanosine
CAS:3’-Deoxy-3'-methylguanosine is a nucleoside that is used in the synthesis of DNA. 3’-Deoxy-3'-methylguanosine is a monophosphate that can be obtained from the phosphoramidites, which are intermediates in the chemical synthesis of nucleotides. 3’-Deoxy-3'-methylguanosine is an activator for DNA polymerases and has been shown to have antiviral, anticancer, and antifungal properties. It has also been shown to be cytotoxic against leukemia cells. 3’-Deoxy-3'-methylguanosine is a novel nucleoside with modified properties.Fórmula:C11H15N5O4Pureza:Min. 95%Peso molecular:281.27 g/mol2',3',5-Tri-O-acetyl-2-chloroadenosine
CAS:2',3',5-Tri-O-acetyl-2-chloroadenosine is a modified nucleoside that has been shown to be a potent activator of the transcriptional activator protein 2 (AP2) and AP1. The ribonucleosides are synthesized by phosphoramidite chemistry and are prepared as monophosphate or diphosphate derivatives. 2',3',5-Tri-O-acetyl-2-chloroadenosine also has antiviral activity against herpes simplex virus type 1 (HSV1). This drug is highly purified and can be used in high quality applications, such as anticancer and antiviral treatments.
Fórmula:C16H18ClN5O7Pureza:Min. 95%Peso molecular:427.8 g/mol4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid
CAS:4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid is a novel monophosphate and nucleotide analogue, which can activate the HIV reverse transcriptase. It has been shown to be cytotoxic to cancer cells in vitro. 4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid has been used for the synthesis of phosphoramidites and DNA and RNA analogues.Fórmula:C6H4F2N2O3Pureza:Min. 95%Peso molecular:190.1 g/molGuanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate
CAS:Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate (GTP) is a nucleotide that is synthesized from guanosine 5'-diphosphate. GTP is an effector molecule that regulates the cytosolic protein synthesis and transport pathways. It binds to a number of proteins, including the guanine nucleotide-binding protein, which regulates the metabolic processes in cells. GTP has been shown to be beneficial in treating cancer by inducing apoptosis and inhibiting tumor growth. In addition, Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate has been shown to inhibit congestive heart failure by reducing free radical production and increasing intracellular adenosine levels.
Fórmula:C10H13Li4N6O13P3Pureza:Min. 95%Peso molecular:546 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine
N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine is a nucleoside analog that is used as an antiviral, anticancer, and antiretroviral agent. It is a potent inhibitor of HIV replication in vitro and in vivo. N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine inhibits the activity of viral reverse transcriptase and DNA polymerase by binding to their RNA template strand. The drug shows efficacy against leukemia cells in vitro and against murine leukemia L1210 cells in vivo. Treatment with N4-acetyl-2'-deoxy-5'-O-DMT cytidine has been shown to reduce the size of tumors in mice with fibrosarcoma, melanoma, or glioma xenografts. N4 acetyl 2’ deoxy 5’ O DMT cytidine is alsoFórmula:C33H35N3O7Pureza:Min. 95%Peso molecular:585.65 g/mol3’-O-(2-Methoxyethyl)adenosine
CAS:3’-O-(2-Methoxyethyl)adenosine is a nucleoside, a kind of building block for DNA. It is an antiviral agent that inhibits viral replication by preventing the incorporation of viral nucleic acid into host DNA. 3’-O-(2-Methoxyethyl)adenosine also has anticancer properties, which makes it useful as a chemotherapeutic agent. 3’-O-(2-Methoxyethyl)adenosine is synthesized from adenosine monophosphate in two steps: first, the methoxy group is attached to the 2’ position of the ribose sugar by phosphoramidite chemistry; second, the 5' hydroxyl group is oxidized to form the phosphate ester.Fórmula:C13H19N5O5Pureza:Min. 95%Peso molecular:325.32 g/mol6-Benzyloxypurine
CAS:6-Benzyloxypurine is a fluorescent compound that can be used to measure the concentration of aqueous solutions. It is used in molecular modeling and as a tracer in bioassays. The binding constants for 6-benzyloxypurine have been determined by fluorescence spectrometry, and it has been shown to inhibit the growth of aerobacter aerogenes at concentrations greater than 0.5 mM. This inhibitor also has an inhibitory effect on the growth of tissue culture cells and wastewater treatment bacteria, such as enterococcus faecalis and pseudomonas aeruginosa. The optimum concentration of 6-benzyloxypurine to inhibit bacterial growth is 1 mM, which corresponds to a pH of ~8.2.
Fórmula:C12H10N4OPureza:Min. 95%Peso molecular:226.23 g/mol1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol
1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol is an activator that can be used in the synthesis of DNA and RNA. It is a novel compound with antiviral properties and anticancer effects. It has been shown to have high purity and quality. This activator is a phosphoramidite that can be used in the synthesis of DNA or RNA and has been modified to have antiviral properties. It is synthesized using deoxyribonucleosides as starting materials, which are obtained from natural sources such as yeast extract or tryptophan.Fórmula:C22H25N5O5Pureza:Min. 95%Peso molecular:439.48 g/mol
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