Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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3'-Deoxy-N6-octanoyladenosine
CAS:3'-Deoxy-N6-octanoyladenosine is a nucleoside that is used to synthesize DNA, RNA, and other nucleic acid molecules. It has antiviral and anticancer properties. 3'-Deoxy-N6-octanoyladenosine has been shown to be an activator of phosphoramidites in the synthesis of DNA. This compound also inhibits the growth of cancer cells by inhibiting the synthesis of DNA and RNA in cells. The purity of this product is >98% and it can be used for research purposes or as a pharmaceutical intermediate.Fórmula:C18H27N5O4Pureza:Min. 95%Peso molecular:377.44 g/mol9-(2'-Deoxy-b-D-xylofuranosyl)adenine
CAS:9-(2'-Deoxy-b-D-xylofuranosyl)adenine is a nucleoside that is used in the treatment of bowel disease, cancer, and other diseases. It is also a potential drug target for antimicrobial agents and pharmacological agents. 9-(2'-Deoxy-b-D-xylofuranosyl)adenine has been shown to inhibit DNA synthesis and cause cell death in mouse tumor cells. It also inhibits adenosine uptake by binding to the A3 receptor, which may be due to its similarity to adenosine. This drug has been shown to have anticancer properties in various carcinoma cell lines. 9-(2'-Deoxy-b-D-xylofuranosyl)adenine is metabolized into deoxyadenosine, which can be converted back into adenosinergic acid or deoxyadenosinergic acid, which are potent inhibitors of DNA polymerase alpha activity.Pureza:Min. 95%1-(2'-Deoxy-2'-fluoro-5'-O-trityl-b-L-arabinofuranosyl)-uracil
1-(2'-Deoxy-2'-fluoro-5'-O-trityl-b-L-arabinofuranosyl)-uracil is a monophosphate nucleotide that is used in antiviral therapy. It inhibits viral DNA synthesis by inhibiting viral DNA polymerase and viral RNA transcription. The drug is currently in phase I clinical trials for the treatment of cancer and AIDS. 1-(2'-Deoxy-2'-fluoro-5'-O-trityl-b-L-arabinofuranosyl)-uracil is a novel compound that has not been described in the literature before. The drug was synthesized by modifying a natural nucleoside, uracil, with fluorine to produce an antiviral agent. This compound has shown anticancer effects in vitro and in vivo experiments as well as antiplasmodial activity against malaria.Fórmula:C28H25FN2O5Pureza:Min. 95%Peso molecular:488.51 g/molN6-Benzoyl-2'-deoxy-5'-O-levulinoyladenosine-3'-CE phosphoramidite
N6-Benzoyl-2'-deoxy-5'-O-levulinoyladenosine-3'-CE phosphoramidite is a novel antiviral agent that exhibits high quality and high purity. It can be used to synthesize DNA, RNA, and other nucleosides. N6-Benzoyl-2'-deoxy-5'-O-levulinoyladenosine-3'-CE phosphoramidite is an activator of the DNA polymerase and an inhibitor of the viral polymerase. This compound has been shown to have anticancer properties in vitro and in vivo.Fórmula:C31H40N7O7PPureza:Min. 95%Peso molecular:653.67 g/molN4-Benzoyl-5'-O-DMT-2'-ethylfluoro-5-methylcytidine 3'-CE phosphoramidite
N4-Benzoyl-5'-O-DMT-2'-ethylfluoro-5-methylcytidine 3'-CE phosphoramidite is a novel, deoxyribonucleosides that has been synthesized with high purity, high quality, and high yield. It is an anticancer drug that inhibits the synthesis of ribonucleotides in DNA and RNA.Pureza:Min. 95%1-(b-D-Arabinofuranosyl)-5-iodouracil
CAS:1-(b-D-Arabinofuranosyl)-5-iodouracil is a synthetic nucleoside that has antiviral and anticancer properties. It is a monophosphate nucleotide that inhibits viral RNA synthesis by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. This inhibitor also blocks DNA synthesis by preventing the incorporation of b-D-arabinofuranosyl monophosphate into DNA. 1-(b-D-Arabinofuranosyl)-5-iodouracil has been shown to be effective in treating various types of cancer, including breast, lung, and prostate cancers. It also exhibits antitumor activity against certain human leukemia cells.Fórmula:C9H11IN2O6Pureza:Min. 95%Peso molecular:370.1 g/mol2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å
The 2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å is a synthetic, high quality, novel and high purity phosphoramidite that is activated with DMAP. The covalent linkage of the nucleoside to the CPG is made by an amidite coupling reaction. The following compounds have been synthesized on this support: ampicillin, chloramphenicol, gentamicin, kanamycin, neomycin and tetracycline. This product is used in anticancer and antiviral research.Pureza:Min. 95%4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine
CAS:4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine is a novel nucleoside analogue that has high purity and high quality. It is an activator of DNA synthesis, diphosphate and monophosphate of deoxyribonucleosides, ribonucleosides and analogues. 4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine has been shown to have antiviral activities against herpes simplex virus type 1 (HSV1) in cell culture.Fórmula:C29H56N4O4Si3Pureza:Min. 95%Peso molecular:609.04 g/molN6-(4-Methyoxybenzoyl)adenosine
CAS:N6-(4-Methoxybenzoyl)adenosine is an adenine base that is a furanose sugar, with a glycosidic bond. The furanose ring has a phenyl group and an adenine base in the conformation of pyranose. The phenyl ring is in the geometry of chair form and is bonded to the 6' position of the adenosine base. N6-(4-Methoxybenzoyl)adenosine has a glycosidic bond at C1' - C5'. It has an angstrom distance between C1'-C2' and C3'-C5'.
Fórmula:C18H19N5O6Pureza:Min. 95%Peso molecular:401.37 g/mol8-Aminoguanosine
CAS:8-Aminoguanosine is a synthetic purine nucleoside that inhibits DNA synthesis. It has been shown to inhibit the proliferation of HL-60 cells, which are a model for human monocytes and neutrophils. 8-Aminoguanosine has been shown to bind to the template strand of DNA and inhibit the incorporation of deoxyribonucleotide triphosphates into the newly synthesized strand. This binding prevents DNA replication by preventing access to the template strand of DNA. 8-Aminoguanosine inhibits cyclin D2, an enzyme required for cell division, at concentrations as low as 0.1 mM, and it also inhibits microtubule assembly. 8-Aminoguanosine has shown in vitro activity against various tumor cell lines including Molt-4 and MCF7 cells, and in vivo activity in a mouse model against C3H/HeJ mice transplanted with Lewis lung carcinoma cells.
Fórmula:C10H14N6O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:298.26 g/molb-Nicotinamide adenine dinucleotide phosphate potassium salt hydrate
CAS:b-Nicotinamide adenine dinucleotide phosphate potassium salt hydrate is a novel anticancer compound that has been shown to inhibit the growth of cancer cells in vitro. The mechanism of action of b-NADP+ is still unknown, but it may involve the inhibition of ribonucleoside reductase and deoxyribonucleoside reductase. It also inhibits viral DNA synthesis, which can be an effective antiviral drug. b-NADP+ is a nucleotide analogue that is synthesized from diphosphate and monophosphate forms, which are activated by phosphoramidites.Fórmula:C21H28N7O17P3•K•(H2O)2Pureza:Min. 95%Peso molecular:818.5 g/molLutonarin
CAS:Lutonarin is a naturally occurring compound in the plant Pueraria lobata. It has been shown to have anti-cancer properties and can be used as an alternative to radiation therapy for cancer treatment. Lutonarin is a membrane-hyperpolarizing agent that is able to pass through the cell membrane, leading to membrane hyperpolarization. Lutonarin also inhibits the production of gamma-aminobutyric acid (GABA), which leads to increased cell proliferation and inhibition of root formation. Lutonarin has been found to inhibit enzyme activities, such as glucose monitoring and protocatechuic acid, phenolic acid, and crystalline cellulose degradation. This leads to reduced glucose levels in blood plasma and reduced degradation of polysaccharides in roots.Fórmula:C27H30O16Pureza:Min. 95%Peso molecular:610.5 g/mol5'-O-DMT-thymidine 3'-thiophosphoramidite
5'-O-DMT-thymidine 3'-thiophosphoramidite is a nucleoside that is used as a building block for the synthesis of DNA and RNA. The compound is also used to create antiviral drugs, anticancer agents, and novel drugs with antimicrobial properties. The chemical structure of 5'-O-DMT-thymidine 3'-thiophosphoramidite has been modified from the natural ribonucleoside thymidine. This modification prevents the phosphorylation of 5'-O-DMT-thymidine 3'-thiophosphoramidite by cellular kinases, which makes this compound more stable in vivo.Fórmula:C44H48N3O8PS2Pureza:Min. 95%Peso molecular:841.97 g/mol1-(2',3',5'-Tri-O-acetyl-b-D-arabinofuranosyl)uracil
1-(2',3',5'-Tri-O-acetyl-b-D-arabinofuranosyl)uracil is a novel nucleoside analog with antiviral and anticancer activities. It is a modified nucleoside that is synthesized from 2',3',5'-triacetyl b-D-arabinofuranosyl uracil. The synthesis of this compound involves the use of acetylation, which produces a monophosphate form of the nucleoside. This product has been shown to be an activator in the synthesis of DNA and RNA.Pureza:Min. 95%Lamivudine 5'-monophosphate ammonium salt
CAS:Lamivudine 5'-monophosphate ammonium salt is a novel antiviral agent that inhibits the viral polymerase by competing with natural dNTPs. It has been shown to be effective against Hepatitis B virus (HBV) and human immunodeficiency virus type 1 (HIV-1). Lamivudine 5'-monophosphate ammonium salt is a synthetic nucleoside that is phosphorylated to form its active form, lamivudine 5'-triphosphate ammonium salt. This drug has been shown to inhibit tumor growth in vivo and in vitro.Fórmula:C8H15N4O6PSPureza:Min. 95%Peso molecular:326.27 g/mol5-Fluoro-2'-O-methyluridine
CAS:5-Fluoro-2'-O-methyluridine is a nucleotide that can be used in the treatment of colorectal adenocarcinoma and other types of cancer. It inhibits the synthesis of DNA by blocking the activity of ribonucleotide reductase, an enzyme that converts ribonucleotides to deoxyribonucleotides. 5-Fluoro-2'-O-methyluridine has been shown to decrease the growth of human glioblastoma cells in cell culture and animal models. The effect is dose dependent and occurs through inhibition of RNA synthesis and protein synthesis, leading to cell death.Fórmula:C10H13FN2O6Pureza:Min. 95%Peso molecular:276.22 g/mol2'-Deoxyguanosine-5'-monophosphate disodium salt hydrate
CAS:2'-Deoxyguanosine-5'-monophosphate disodium salt hydrate is a novel nucleoside diphosphate that has antiviral and anticancer effects. It inhibits the synthesis of viral DNA, RNA, and proteins, which can lead to cell death by apoptosis. 2'-Deoxyguanosine-5'-monophosphate disodium salt hydrate also inhibits the proliferation of cancer cells and other malignant cells.Fórmula:C10H12N5Na2O7PPureza:Min. 95%Peso molecular:391.19 g/mol5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine
CAS:5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine is a nucleoside, a type of chemical compound containing both a sugar (deoxyribose) and an organic molecule (a base). It is an antiviral agent that inhibits the production of viral DNA by inhibiting the enzyme DNA polymerase. 5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine is also an anticancer agent that can inhibit the production of cancer cells in vitro and in vivo. This product is a novel monophosphate nucleotide analog with high purity and CAS number 1422361-25-8.Pureza:Min. 95%5-Bromo-2',3'-dideoxyuridine
CAS:5-Bromo-2',3'-dideoxyuridine is a nucleoside analogue that is used as a chemotherapeutic drug against various types of cancer. It has been shown to have anti-tumour activity by interfering with the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). 5-Bromo-2',3'-dideoxyuridine binds to the sugar ring in DNA and inhibits the enzyme DNA polymerase from synthesizing DNA. This drug also stabilizes conformations of the molecule, which are responsible for its pharmacological effects.
5-Bromo-2',3'-dideoxyuridine can be found in two different crystal structures, monoclinic and tetragonal. The monoclinic form is stabilized by hydrogen bonds between the puckers in the sugar ring and hydrogen bonds to neighboring molecules. This form is more soluble than the tetragonal form,Pureza:Min. 95%Emtricitabine-d2,15N
CAS:Emtricitabine-d2,15N is a labelled version of emtricitabine. It is a nucleoside reverse transcriptase inhibitor that inhibits the HIV-1 virus by blocking the activity of the enzyme needed to convert RNA into DNA. This drug also offers long-term efficacy and can be used in combination with other antiretroviral agents including tenofovir alafenamide hemifumarate (TAF) and tenofovir disoproxil fumarate (TDF). The addition of TAF or TDF to emtricitabine-d2,15N provides an active antiretroviral therapy for HIV/AIDS patients. Emtricitabine-d2,15N has shown to reduce viral load significantly in people taking it as part of their treatment regimen.
Fórmula:C8D10FN3O3SPureza:Min. 95%Peso molecular:257.3 g/mol
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