Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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3'-Deoxy-5'-O-trityluridine
CAS:3'-Deoxy-5'-O-trityluridine is a nucleoside that is structurally related to uridine. It belongs to the class of nucleosides and has a hydroxyl group at the 3' position. The 5' position is modified by an anion (most often trityl) sterically, which prevents hydrolysis by esterases or phosphatases. The efficiency of this modification can be increased by using diethyl phosphate as the protecting agent. This modification also provides protection against nucleophiles, such as hydroxyl groups in nucleosides or phosphite triester derivatives. 3'-Deoxy-5'-O-trityluridine is used in the synthesis of other nucleosides and as a substrate for diffraction experiments.Fórmula:C28H26N2O5Pureza:Min. 95%Peso molecular:470.53 g/molN2-Benzoyl-2'-deoxy-5'-O-DMT-guanosine
CAS:N2-Benzoyl-2'-deoxy-5'-O-DMT-guanosine is a novel and potent anticancer nucleoside with antiviral activity. It is an analog of 2'-deoxy-5'-O-DMT guanosine, which was reported to be the first phosphoramidite nucleoside. N2-Benzoyl-2'-deoxy-5'-O-DMT-guanosine is an excellent candidate for DNA synthesis and has been shown to inhibit viral replication. This product is also of high purity and high quality, and can be used in research applications.Fórmula:C38H35N5O7Pureza:Min. 95%Peso molecular:673.71 g/molAdenosine 5'-diphosphate potassium salt
CAS:Adenosine 5'-diphosphate potassium salt can be used as a substrate for a variety of protein kinases known as AMP-activated protein kinases (AMPK)Fórmula:C10H14N5O10P2·KPureza:Min. 95%Cor e Forma:PowderPeso molecular:465.29 g/mol4-Methyl-6-phenyl-pyrimidine-2-thiol
CAS:4-Methyl-6-phenyl-pyrimidine-2-thiol is a copper(II) dehalogenating agent that belongs to the group of amplifiers. It has been used in the preparation of syntheses, including as an intermediate in the synthesis of phenylpyrimidines and amidines. The synthesis of 4-methyl-6-phenyl-pyrimidine-2-thiol can be accomplished by condensation of phleomycin with a biaryl. This reaction is followed by oxidation to give a biaryl sulfone, which is then reduced with hydrogen gas and ammonium formate.Fórmula:C11H10N2SPureza:Min. 95%Peso molecular:202.28 g/mol5'-Deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine
CAS:5'-Deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine is a modified nucleoside analog that inhibits the growth of viruses. It has been shown to be active against herpes simplex virus type 1 and 2, varicella zoster virus, cytomegalovirus, and Epstein-Barr virus. This drug is used as an antiviral medication in the treatment of viral infections.Fórmula:C24H26N4O4Pureza:Min. 95%Peso molecular:434.5 g/mol2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-O-succinate triethylammonium salt
2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-O-succinate triethylammonium salt is a nucleoside that is modified with a 2,2,2-trifluoroethoxycarbonyl group on the 5' position of the sugar moiety. It is an activator for phosphoramidites in DNA synthesis and has been shown to have anticancer activity. It is also used as an antiviral agent and to treat HIV and herpes virus infections. This compound has a molecular weight of 439.5 g/mol and its CAS number is 62273-03-3.
Fórmula:C34H32FN2O10·C6H16NPureza:Min. 95%Cor e Forma:SolidPeso molecular:749.84 g/molN2-Isobutyryl-2'-O-(2-methylacetamido)guanosine
N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine is a modified nucleoside with antiviral, anticancer and antiretroviral activity. It is a novel monophosphate that has been shown to be effective against hepatitis B and HIV. N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine inhibits the synthesis of viral DNA by acting as an activator of DNA polymerases.Pureza:Min. 95%2'-Deoxyadenosine 5'-a-thiotriphosphate sodium salt
2'-Deoxyadenosine 5'-a-thiotriphosphate sodium salt is an antiviral nucleotide analog that has been modified to have a novel structure. It is phosphorylated in vivo to form 2'-deoxyadenosine 5'-a-thiotriphosphate. The nucleoside can inhibit viral DNA synthesis and help prevent the spread of HIV, herpes virus type I, herpes virus type II, influenza virus, and other viruses. This compound also has anticancer activity and has been shown to be effective against leukemia cells.Pureza:Min. 95%Guanosine 3',5'-diphosphate tetralithium salt
CAS:Guanosine 3',5'-diphosphate tetralithium salt is a nucleoside that has antiviral and anticancer properties. It is synthesized by reacting guanosine with lithium tetrabutylammonium tetraiodide. This nucleotide can be used as a precursor for DNA synthesis, deoxyribonucleosides, and phosphoramidites. Guanosine 3',5'-diphosphate tetralithium salt has been shown to activate the synthesis of proteins in the absence of adenosine triphosphate (ATP).Fórmula:C10H11Li4N5O11P2Pureza:Min. 95%Peso molecular:466.93 g/mol5'-O-Trityl-3'-b-hydroxythymidine
CAS:5'-O-Trityl-3'-b-hydroxythymidine is a nucleoside that is synthesized by the reduction of a pyrimidine with xylene. This molecule has been shown to have antibacterial activity, and also activates p53 in human cells. 5'-O-Trityl-3'-b-hydroxythymidine has been shown to inhibit the growth of cancer cells in a dose dependent manner. The functional theory for this finding is that 5'-O-Trityl-3'-b-hydroxythymidine may bind to DNA, preventing RNA polymerase from transcribing DNA into mRNA.
Fórmula:C29H28N2O6Pureza:Min. 95%Peso molecular:500.54 g/mol6-Chloro-7-deaza-9-(a-D-ribofuranosyl)purine
CAS:6-Chloro-7-deaza-9-(a-D-ribofuranosyl)purine is an anticancer drug that belongs to the class of nucleosides. It inhibits DNA and RNA synthesis by blocking the incorporation of nucleotides into DNA or RNA. This drug may also inhibit viral replication by blocking viral polymerase activity. 6-Chloro-7-deaza-9-(a-D-ribofuranosyl)purine has been shown to be a potent activator of phosphoramidites, which are used in chemical synthesis. This novel compound is synthesized using modified diphosphate chemistry and purified to high purity.Fórmula:C11H12ClN3O4Pureza:Min. 95%Peso molecular:285.68 g/mol9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine
CAS:9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine is a modified nucleoside that is used as an antiviral and anticancer agent. It acts as an activator for the synthesis of DNA, RNA, and protein. 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine also inhibits the growth of cancer cells by interfering with the division process. This drug is synthesized from 9-(5'-deoxy-5'-iodo-b-D-ribofuranosyl) -2,6 difluoro adenine (diFdA). The Ribonucleosides are then prepared in a similar manner to other nucleosides by using phosphoramidites. The product is then purified using HPLC.
Fórmula:C10H11F2N5O3Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:287.23 g/molThymidine-5'-diphosphate-6-deoxy-D-allose
Thymidine-5'-diphosphate-6-deoxy-D-allose (TDP) is a high quality monophosphorylated nucleoside that is used as an activator, anticancer, and antiviral agent. TDP has been modified to improve the efficacy and safety of cancer treatments by enhancing the cytotoxicity of chemotherapeutics. TDP also has antiviral properties and can be used in the treatment of HIV infections by inhibiting viral replication.
Pureza:Min. 95%2'-O-(tert-Butyldimethylsilyl)-3'-deoxy-5'-O-trityluridine
CAS:2'-O-(tert-Butyldimethylsilyl)-3'-deoxy-5'-O-trityluridine is a nucleoside that has antiviral and anticancer properties. It is a monophosphate of uridine, which is an important precursor in the synthesis of DNA and RNA. This product has been modified to improve its purity and quality, making it suitable for use in laboratory research.Fórmula:C34H40N2O5SiPureza:Min. 95%Peso molecular:584.78 g/mol2'/3'-(N-Methylanthraniloyl)-adenosine-5'-triphosphate triethylammonium salt
CAS:2'/3'-(N-Methylanthraniloyl)-adenosine-5'-triphosphate triethylammonium salt is a phosphoramidite, deoxyribonucleoside that is active as an antiviral. It inhibits the production of viral DNA and RNA by binding to the polymerase enzyme that copies the viral genome. This drug has been shown to be effective in vitro and in vivo against a wide range of viruses, including HIV, herpes simplex virus type 1 and 2, cytomegalovirus, varicella zoster virus, influenza A virus, and poliovirus. It also has anticancer activity by inhibiting cell proliferation.Fórmula:C18H23N6O14P3Pureza:Min. 95%Peso molecular:640.33 g/molN4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-deoxycytidine
N4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-deoxycytidine is a monophosphate nucleoside analogue. It has antiviral and anticancer properties, as well as the ability to activate DNA synthesis. This product is synthesized from 2'-deoxycytidine and 4-benzoyl chloride in the presence of tert-butyldimethylsilyl chloride. It is available for sale as a white powder with a purity of 99%.Fórmula:C22H31N3O5SiPureza:Min. 95%Cor e Forma:PowderPeso molecular:445.58 g/mol3'-Chloro-3'-deoxy-5'-O-tritylthymidine
CAS:3'-Chloro-3'-deoxy-5'-O-tritylthymidine (3CT) is an antiviral and anticancer drug that is a modified nucleoside. It is synthesized by reacting 3'-chloro-5'-O-tritylthymidine with trichloroacetonitrile. 3CT inhibits the synthesis of DNA and RNA, which may have antiviral and anticancer effects. It can be used to treat hepatitis B virus, herpes simplex virus, human papillomavirus, Epstein-Barr virus, and Kaposi's sarcoma. 3CT has been shown to be effective in treating cancer cells in culture by inhibiting DNA synthesis.Fórmula:C29H27ClN2O4Pureza:Min. 95%Peso molecular:503 g/molN6-Benzoyl-5'-O-DMT-adenosine 3'-CE phosphoramidite
N6-Benzoyl-5'-O-DMT-adenosine 3'-CE phosphoramidite is a novel nucleoside that has been modified to protect the 2' hydroxyl group from attack by nucleases. This modification makes N6-Benzoyl-5'-O-DMT-adenosine 3'-CE phosphoramidite resistant to degradation and allows for its use in a variety of applications, such as anticancer, antiviral, and DNA sequencing.Pureza:Min. 95%E-5-(2-Carbomethoxyvinyl)-2'-deoxy-5'-O-DMT-uridine
CAS:E-5-(2-Carbomethoxyvinyl)-2'-deoxy-5'-O-DMT-uridine is a monophosphate nucleoside analog that has been modified to be resistant to antiviral ribonucleases. This drug is phosphorylated in vivo to the corresponding diphosphate and triphosphate, which inhibits viral DNA synthesis and thus prevents the virus from replicating. E-5-(2-Carbomethoxyvinyl)-2'-deoxy-5'-O-DMT-uridine can be used as an antiviral agent against herpes simplex virus (HSV).Fórmula:C34H34N2O9Pureza:Min. 95%Peso molecular:614.66 g/molS-(4-Nitrobenzyl)-6-thioguanosine
CAS:S-(4-Nitrobenzyl)-6-thioguanosine is a transport inhibitor that has been shown to be active against leukemia. This drug inhibits the uptake of leukocytes into the bone marrow, which prevents their proliferation and development. S-(4-Nitrobenzyl)-6-thioguanosine also inhibits the synthesis of adenosine in erythrocytes, which leads to the accumulation of uridine and then to an increase in the levels of ATP. This drug can be used to treat chronic lymphocytic leukemia.Fórmula:C17H18N6O6SPureza:Min. 95%Peso molecular:434.43 g/mol
