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Nucleosídeos

Nucleosídeos

Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.

Foram encontrados 3569 produtos de "Nucleosídeos"

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  • Thymidine-5'-diphosphate-6-deoxy-D-allose


    <p>Thymidine-5'-diphosphate-6-deoxy-D-allose (TDP) is a high quality monophosphorylated nucleoside that is used as an activator, anticancer, and antiviral agent. TDP has been modified to improve the efficacy and safety of cancer treatments by enhancing the cytotoxicity of chemotherapeutics. TDP also has antiviral properties and can be used in the treatment of HIV infections by inhibiting viral replication.</p>
    Pureza:Min. 95%

    Ref: 3D-NT29841

    5mg
    1.628,00€
    10mg
    2.867,00€
  • 2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate ammonium salt

    CAS:
    <p>2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate ammonium salt (2'OMeEtGTP) is an antiviral agent that is used as a component of an antiviral drug. It inhibits the viral enzyme DNA polymerase, which prevents viral replication and transcription. This compound has been shown to have anticancer properties in vitro and in vivo in rat models. 2'OMeEtGTP is synthesized by reacting the nucleoside phosphoramidite 2'OMeEtGTP with triethylammonium phosphate (TEAP).</p>
    Pureza:Min. 95%

    Ref: 3D-NM162963

    10mg
    4.087,00€
  • 3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-2'-fluoroarabinocytidine

    CAS:
    3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-2'-fluoroarabinocytidine is a novel nucleoside analogue that has been synthesized to inhibit the activity of DNA polymerase. This compound is also an activator of diphosphate and ribonucleoside monophosphate. 3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-2'-fluoroarabinocytidine has been shown to inhibit the replication of herpes simplex virus type 1 in cell culture and the replication of human cytomegalovirus in cell culture. 3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-- 2'-fluoroarabinocytidine does not have any antiviral activity against HIV.
    Pureza:Min. 95%

    Ref: 3D-FD144469

    100mg
    303,00€
    250mg
    454,00€
  • 3',5'-Di-o-acetyl-O6-phenyl-2'-deoxyinosine

    CAS:
    3',5'-Di-O-acetyl-O6-phenyl-2'-deoxyinosine is a nucleoside analog that has antiviral and anticancer activities. It is an activator of the enzyme ribonucleotide reductase and has been shown to be effective against herpes simplex virus type 1 and 2, cytomegalovirus, Epstein Barr virus, human immunodeficiency virus type 1, and Kaposi sarcoma cells. 3',5'-Di-O-acetyl-O6-phenyl-2'-deoxyinosine also inhibits the production of tumor necrosis factor alpha (TNFα), which can cause inflammatory reactions in the body. This compound is a modified nucleoside with high purity and quality. It has CAS number 133471-06-4.
    Fórmula:C20H20N4O6
    Pureza:Min. 95%
    Peso molecular:412.4 g/mol

    Ref: 3D-IFA47106

    5g
    1.707,00€
  • 4'-Azidothymidine 5-triphosphate

    CAS:
    4'-Azidothymidine 5-triphosphate (4AZTTP) is a deoxyribonucleoside that has been synthesized as an analog to thymidine. It has potent inhibitory activity against human immunodeficiency virus (HIV), and has been shown to be more effective than 2',3'-dideoxyinosine in inhibiting HIV replication. 4AZTTP inhibits the viral enzyme reverse transcriptase, which is crucial for the replication of HIV. This drug is activated by cellular enzymes and phosphorylated to 4'-azidothymidine 5'-triphosphate monophosphate, which can then bind to the viral DNA template and inhibit synthesis of RNA strands. The kinetic properties of 4AZTTP have been studied in detail using human lymphocytes as a model system for HIV infection.
    Fórmula:C10H16N5O14P3
    Pureza:Min. 95%
    Peso molecular:523.18 g/mol

    Ref: 3D-NA13340

    1g
    2.440,00€
  • 8-Aminoadenosine-5'-triphosphate sodium salt - 10mM aqueous solution

    CAS:
    8-Aminoadenosine-5'-triphosphate sodium salt is a phosphoramidite that is used to synthesize antiviral nucleosides. It is a high quality product that can be used as an activator in the synthesis of ribonucleosides and deoxyribonucleosides. 8-Aminoadenosine-5'-triphosphate sodium salt has been shown to inhibit the growth of cancer cells.
    Fórmula:C10H17N6O13P3·xNa
    Pureza:Min. 95%
    Peso molecular:522.2 g/mol

    Ref: 3D-NA12011

    1mg
    353,00€
    2mg
    497,00€
    5mg
    872,00€
    10mg
    1.184,00€
    25mg
    1.973,00€
  • 5'-O-DMT-2'-O-hexylamino-5-methyluridine

    CAS:
    5'-O-DMT-2'-O-hexylamino-5-methyluridine is a nucleoside analog that is used in cancer treatment. It is synthesized by the chemical modification of uridine, which is converted to 5'-O-DMT-2'-O-hexylamino-5-methyluridine by reacting with 2',3'-dideoxyadenosine and 5,6,7,8,-tetrahydroisoquinoline. The monophosphate form of 5'-O-DMT-2'-O-hexylamino-5-methyluridine may be converted to the diphosphate form by phosphorylation with ATP. In addition to its anticancer effects, 5'-O-DMT-2'-O-hexylamino-5-methyluridine has antiviral and antiretroviral effects due to its inhibition of viral DNA synthesis.
    Fórmula:C37H45N3O8
    Pureza:Min. 95%
    Peso molecular:659.79 g/mol

    Ref: 3D-ND08520

    25mg
    303,00€
    50mg
    353,00€
    100mg
    497,00€
    250mg
    793,00€
  • 9-(2-C-Methyl-b-D-ribofuranosyl)purine

    CAS:
    <p>9-(2-C-Methyl-b-D-ribofuranosyl)purine is a nucleoside that is used as an activator in the synthesis of phosphoramidites. 9-(2-C-Methyl-b-D-ribofuranosyl)purine has antiviral and anticancer properties, and it also inhibits the growth of bacteria. This nucleoside is synthesized from 2,4,6-trichlorophenylisocyanate and 5'-O-(4,4'-dimethoxytrityl)-beta-D-ribofuranose. The chemical name for 9-(2-C methyl b D ribofuranosyl)purine is 690269 - 86 - 4.</p>
    Fórmula:C11H14N4O4
    Pureza:Min. 95%
    Peso molecular:266.25 g/mol

    Ref: 3D-NM144529

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  • 4'-Nitrobenzoyl-6-selenoinosine

    CAS:
    4'-Nitrobenzoyl-6-selenoinosine is a monophosphate nucleoside that is synthesized by the phosphoramidite method. It has been shown to have antiviral and anticancer activities. The compound inhibits the synthesis of DNA and RNA, which may be due to its ability to inhibit the enzyme ribonucleotide reductase. 4'-Nitrobenzoyl-6-selenoinosine has also been shown to activate cellular transcription factors such as NF-κB and AP-1, resulting in increased expression of genes involved in apoptosis.
    Fórmula:C17H15N5O7Se
    Pureza:Min. 95%
    Peso molecular:480.29 g/mol

    Ref: 3D-NN08056

    5mg
    303,00€
    10mg
    414,00€
  • Fluorescein alkynylamino-ATP - 1.0 mM solution

    CAS:
    Fluorescein alkynylamino-ATP is a fluorescent nucleotide analog that is used in molecular biology for the detection of DNA. It is labeled with tetramethylrhodamine, which can be detected using a fluorescence microscope. Fluorescein alkynylamino-ATP is a postsynthetic modification to DNA, which means it is added after the DNA has been synthesized. This molecule can be incorporated into the growing strand by either monoaddition or polymerase extension. Fluorescein alkynylamino-ATP binds to the 3' end of a primer during polymerase chain reaction (PCR) and can be detected using electrophoresis and sequence analysis.
    Fórmula:C41H41N6O20P3
    Pureza:Min. 95%
    Peso molecular:1,030.71 g/mol

    Ref: 3D-NF16725

    25µg
    700,00€
  • 5,6-Dihydro-5'-O-DMT-thymidine 3'-CE phosphoramidite


    This is a synthetic DNA analogue that is used in the synthesis of oligonucleotides. It is a phosphoramidite in which the 5,6-dihydro-5'-O-DMT group has been modified to allow for incorporation into DNA and RNA. This compound has antiviral and anticancer activities.
    Fórmula:C40H51N4O8P
    Pureza:Min. 95%
    Peso molecular:746.83 g/mol

    Ref: 3D-PD09179

    250mg
    1.047,00€
  • 3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine


    3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine is a novel nucleoside analogue with high purity and quality. It is a DNA activator that has been shown to be active against both RNA and DNA viruses. 3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine phosphorylates to the corresponding monophosphate, which inhibits viral DNA synthesis by competitive inhibition of diphosphate formation. This compound has also been shown to be an effective inhibitor of HIV replication in vitro.
    Fórmula:C24H20N8O4
    Pureza:Min. 95%
    Peso molecular:484.47 g/mol

    Ref: 3D-NA08672

    1mg
    303,00€
    5mg
    537,00€
    10mg
    814,00€
  • 2'-O-(2-Ethoxy-2-oxoethyl)adenosine


    <p>2'-O-(2-Ethoxy-2-oxoethyl)adenosine is a nucleoside that is a modified version of adenosine. It is phosphorylated to form 2'-O-(2-ethoxy-2-oxoethyl)adenosin-5'-yl monophosphate, which has antiviral activity and is used as an antiviral agent in the treatment of herpes simplex virus. The chemical structure of this nucleoside is novel, and it binds to the ribonucleotide reductase enzyme to prevent the synthesis of DNA and RNA. This drug also has anticancer properties, but it is not active against bacterial infections.</p>
    Pureza:Min. 95%

    Ref: 3D-NE158848

    250mg
    304,00€
    500mg
    336,00€
  • 1-(3'-O-Nosyl-5'-O-trityl-2'-deoxy-b-D-lyxofuranosyl)thymine

    CAS:
    Ribonucleosides are nucleosides that contain ribose as their pentose sugar. Ribonuclesides are synthetic, modified ribonucleosides that have been modified to include a 2'-deoxy-b-D-lyxofuranosyl group at the 3' position. Ribonuclesides activate antiviral activity by inhibiting viral DNA synthesis and protein synthesis. They also inhibit cancer cell proliferation by inhibiting DNA synthesis and RNA synthesis.
    Fórmula:C35H31N3O9S
    Pureza:Min. 95%
    Peso molecular:669.7 g/mol

    Ref: 3D-NN07310

    50mg
    303,00€
    100mg
    416,00€
  • 2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine-5'-triphosphate


    <p>2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine-5'-triphosphate is a novel synthetic nucleoside analog with antiviral and anticancer properties. It is an activator of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine has been shown to be effective against human leukemia cells in vitro and in vivo.</p>
    Fórmula:C10H17ClN5O12P3
    Pureza:Min. 95%
    Peso molecular:527.64 g/mol

    Ref: 3D-NA09401

    1µg
    303,00€
    5µg
    663,00€
    10µg
    977,00€
  • N4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate


    <p>N4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate is a synthetic nucleoside that has antiviral activity. It is a modification of the natural nucleoside cytidine, where the 4th position of the ribose ring is substituted with an acetyl group and the 2' position of the sugar moiety is substituted with a 2' deoxyribofuranosyl group. N4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate inhibits viral replication by inhibiting viral RNA synthesis. Its antiviral properties may be due to its ability to inhibit DNA polymerase and reverse transcriptase, which are enzymes that synthesize DNA from RNA.</p>
    Pureza:Min. 95%

    Ref: 3D-NA158778

    25mg
    303,00€
    50mg
    355,00€
  • 3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine

    CAS:
    3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine is a novel antiviral agent that is synthesized as a deoxyribonucleoside monophosphate. It inhibits viral DNA polymerase and RNA synthesis by competitively inhibiting the incorporation of diphosphates into viral DNA. It has been shown to be active against herpes simplex virus type 1 and 2, vaccinia virus, influenza A virus, and Sindbis virus. 3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine has also been shown to have anticancer properties in vitro and in vivo.
    Fórmula:C21H23N5O6
    Pureza:Min. 95%
    Peso molecular:441.44 g/mol

    Ref: 3D-ND16695

    10mg
    303,00€
    25mg
    401,00€
    50mg
    649,00€
    100mg
    1.052,00€
    250mg
    1.918,00€
  • 3'-Chloro-3'-deoxy-5'-O-tritylthymidine

    CAS:
    3'-Chloro-3'-deoxy-5'-O-tritylthymidine (3CT) is an antiviral and anticancer drug that is a modified nucleoside. It is synthesized by reacting 3'-chloro-5'-O-tritylthymidine with trichloroacetonitrile. 3CT inhibits the synthesis of DNA and RNA, which may have antiviral and anticancer effects. It can be used to treat hepatitis B virus, herpes simplex virus, human papillomavirus, Epstein-Barr virus, and Kaposi's sarcoma. 3CT has been shown to be effective in treating cancer cells in culture by inhibiting DNA synthesis.
    Fórmula:C29H27ClN2O4
    Pureza:Min. 95%
    Peso molecular:503 g/mol

    Ref: 3D-NC07419

    100mg
    303,00€
    250mg
    416,00€
  • Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt

    CAS:
    Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt is a nucleoside that is a synthetic analog of thymidine. It has antiviral activity and is used in the synthesis of DNA and RNA. This product has shown to be effective against HIV, influenza, polio, herpes, and human papillomavirus. Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt can also be used for the synthesis of phosphoramidites for oligonucleotide synthesis.
    Fórmula:C20H26N7O10P·NH3
    Pureza:Min. 95%
    Peso molecular:572.47 g/mol

    Ref: 3D-NT08058

    1mg
    303,00€
    2mg
    394,00€
    5mg
    673,00€
    10mg
    837,00€
  • 5’-O-DMT cET-N2-isopropylguanosine 3’-OCE amidite

    CAS:
    <p>Please enquire for more information about 5'-ODMT cEt G Phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C46H56N7O9P
    Peso molecular:881.95 g/mol

    Ref: 3D-PO184478

    250mg
    A consultar