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Nucleosídeos

Nucleosídeos

Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.

Foram encontrados 3567 produtos de "Nucleosídeos"

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  • 3'-Deoxy-5-methyluridine

    CAS:
    <p>3'-Deoxy-5-methyluridine (3'-DMAU) is a synthetic nucleoside that is used in the treatment of viral infections. 3'-DMAU has antiviral and anticancer activity, and it has been used to synthesize DNA for genetic engineering. It has shown promising results in the treatment of HIV as well as in the prevention of cancer metastasis. 3'-DMAU inhibits DNA synthesis by binding to the enzyme RNA polymerase, which blocks its interaction with ribonucleosides, thus inhibiting RNA synthesis. In addition, 3'-DMAU causes cell death by inhibiting protein synthesis. The drug is activated by phosphorylation to form 5'-triphosphate and 5'-diphosphate derivatives, which inhibit DNA and RNA synthesis at multiple sites within the cell.</p>
    Fórmula:C10H14N2O5
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:242.23 g/mol

    Ref: 3D-ND02776

    1g
    1.440,00€
    10mg
    234,00€
    25mg
    391,00€
    50mg
    577,00€
    100mg
    804,00€
  • 8-Nitroguanosine

    CAS:
    <p>8-Nitroguanosine is a nucleotide analogue that inhibits the activity of cyclic GMP in cells. It has been found to inhibit the growth of bacteria and cancer cells, as well as to stimulate the production of reactive oxygen species in brain cells. 8-Nitroguanosine has also been shown to inhibit the activity of cyclase enzymes in liver cells, which may be useful for treating liver disease. 8-Nitroguanosine is used as a chemical base for monoclonal antibodies that are used to study brain functions and pathogenic mechanisms.</p>
    Fórmula:C10H12N6O7
    Pureza:Min. 95%
    Peso molecular:328.24 g/mol

    Ref: 3D-NN03322

    10mg
    1.085,00€
    25mg
    2.112,00€
    50mg
    3.697,00€
    100mg
    4.225,00€
    250mg
    4.754,00€
  • Adenylyl-3'-5'-guanosine sodium salt

    CAS:
    <p>3'-Adenylyl-5'-guanosine ammonium salt is a dinucleoside that competes with guanosine for binding to the enzyme adenylate cyclase. This reaction leads to increased levels of cyclic AMP, which causes an increase in the rate of viral replication. 3'-Adenylyl-5'-guanosine ammonium salt has been shown to inhibit the growth of pyogenic bacteria such as Streptococcus pyogenes and has also been used to treat influenza infections. 3'-Adenylyl-5'-guanosine ammonium salt is an inorganic compound that is found in tobacco. It can be synthesized from uridine and p-nitrophenyl phosphate by the reaction: 3'--O--(CH2)4--COOH + H2N--PO4--&gt; 3'--O--(CH2)4--CONH2 + H3PO4</p>
    Fórmula:C20H24N10O11P·Na
    Pureza:Min. 95%
    Peso molecular:634.43 g/mol

    Ref: 3D-NA46044

    1mg
    733,00€
    2mg
    1.275,00€
    5mg
    2.181,00€
    10mg
    3.355,00€
  • Zeatin riboside

    CAS:
    <p>Zeatin riboside is a naturally occurring compound that belongs to the group of nucleotides. It is synthesized in plants and bacteria, and has been shown to have physiological activities in both these organisms. Rootstocks are typically used as the optimum concentration for zeatin riboside. Zeatin riboside has been shown to be effective against bacterial strains that cause plant diseases, such as bacterial strain Xanthomonas campestris pv. corylina. Zeatin riboside also inhibits the growth of plant pathogens by increasing adenine nucleotide levels in root cells, which leads to an increase in photosynthetic activity and a decrease in the production of chemical pesticides. The optimum pH for zeatin riboside is 8-9.</p>
    Fórmula:C15H21N5O5
    Pureza:Min. 90%
    Cor e Forma:Powder
    Peso molecular:351.36 g/mol

    Ref: 3D-NZ08027

    25mg
    182,00€
    50mg
    291,00€
    100mg
    410,00€
    250mg
    719,00€
    500mg
    1.083,00€
  • 5′-O-DMT-LNA N-Bz 5-Me cytidine

    CAS:
    <p>5′-O-DMT-LNA N-Bz 5-Me cytidine is a protected LNA cytidine nucleoside.</p>
    Fórmula:C39H37N3O8
    Pureza:Min. 95%
    Peso molecular:675.73 g/mol

    Ref: 3D-ND182844

    1g
    729,00€
    2g
    1.085,00€
    100mg
    291,00€
    250mg
    410,00€
    500mg
    547,00€
  • Propionyl coenzyme A lithium salt

    CAS:
    <p>Propionyl coenzyme A lithium salt is a phosphoramidite that can be used in the synthesis of DNA and RNA. It is a novel chemical compound that has been modified to include ribonucleosides in addition to deoxyribonucleosides. This product is of high purity and quality, with a CAS number of 108321-21-7.</p>
    Fórmula:C24H40N7O17P3S·xLi
    Pureza:85%
    Cor e Forma:White Powder
    Peso molecular:823.6 g/mol

    Ref: 3D-NP47204

    1mg
    238,00€
    2mg
    346,00€
    5mg
    491,00€
    10mg
    753,00€
    25mg
    1.198,00€
  • Spacer-c3 cep

    CAS:
    <p>Spacer-C3 Cep is a novel modified nucleoside phosphoramidite. It has been chemically modified with a spacer arm and 3-Cep (1,2-diaminoethane). Spacer-C3 Cep is an activator for DNA polymerases, which are enzymes that synthesize DNA from deoxyribonucleosides. The modified nucleoside phosphoramidite has antiviral and anticancer activities. It can be used in the synthesis of oligodeoxyribonucleotides for gene therapy or as a monophosphate for the preparation of DNA probes. Spacer-C3 Cep can also be used to synthesize ribonucleotide analogs that inhibit viral replication by inhibiting RNA synthesis.</p>
    Fórmula:C33H43N2O5P
    Pureza:Min. 95%
    Peso molecular:578.7 g/mol

    Ref: 3D-KEA89423

    250mg
    547,00€
    500mg
    729,00€
  • 2'-Deoxyinosine-5'-triphosphate sodium,100mM aqueous solution

    CAS:
    <p>2'-Deoxyinosine-5'-triphosphate sodium (2'-dITP) is a modified nucleotide that has antiviral and anticancer properties. It has been shown to be an activator for ribonucleosides, deoxyribonucleosides, and DNA. 2'-DITP has also been shown to inhibit the growth of human breast cancer cells in vitro.</p>
    Fórmula:C10H11N4Na4O13P3
    Pureza:Min. 95%
    Cor e Forma:Clear Liquid
    Peso molecular:580.09 g/mol

    Ref: 3D-ND181209

    25ml
    1.981,00€
    50ml
    2.957,00€
    100ml
    4.013,00€
  • 2'-Deoxyuridine-5'-monophosphate disodium salt

    CAS:
    <p>2'-Deoxyuridine-5'-monophosphate disodium salt (2DUMP) is a nucleoside analog that inhibits the synthesis of DNA and RNA by inhibiting the enzyme thymidylate synthase. 2DUMP is a covalent inhibitor of thymidylate synthase, which prevents the formation of dTMP from deoxyuridine 5'-triphosphate. This compound has been shown to be effective in treating squamous cell cancer and hyperproliferative diseases such as chronic myelogenous leukemia. 2DUMP is also used as an antiviral agent against HIV, herpes simplex virus, and varicella zoster virus. It has been shown to bind to benzalkonium chloride (BAK) in biological samples such as serum or plasma.<br>2DUMP binds to BAK through a covalent linkage between the 3' hydroxyl group on BAK and the phosphate group on 2DUMP</p>
    Fórmula:C9H11N2O8PNa2
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:352.15 g/mol

    Ref: 3D-ND02992

    1g
    336,00€
    2g
    478,00€
    5g
    962,00€
    500mg
    229,00€
  • N6-Benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution

    CAS:
    <p>N6-Benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an analog of adenosine triphosphate (ATP). It is used in the study of protein kinase C. ATP and its analogs are able to phosphorylate proteins and regulate their activity. This study has shown that N6-benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an atp analog that activates protein kinase C, leading to the phosphorylation of proteins. This analog also inhibits tyrosine kinases, which may be due to its ability to inhibit the reuptake of serotonin and other transmitters.</p>
    Fórmula:C17H22N5O13P3·xNa
    Pureza:Min. 95%
    Cor e Forma:Colorless Powder
    Peso molecular:597.3 g/mol

    Ref: 3D-NB45917

    1mg
    390,00€
    2mg
    602,00€
    5mg
    1.102,00€
    10mg
    1.653,00€
    20mg
    2.952,00€
  • N2-Acetyl-5'-O-DMT-guanosine

    CAS:
    <p>N2-Acetyl-5'-O-DMT-guanosine is a novel anticancer nucleoside that has been synthesized to mimic the natural nucleotides found in DNA. It is phosphorylated to N2-acetyl-5'-O-DMT-guanosine monophosphate, which can be converted back to the active form of N2-acetyl-5'-O-DMT guanosine by phosphatases. This agent activates DNA synthesis and inhibits viral replication, including HIV and herpes simplex virus. The antiviral activity is due to its inhibition of viral DNA polymerase and diphosphate kinase.</p>
    Pureza:Min. 95%

    Ref: 3D-NA138797

    1g
    1.085,00€
    5g
    2.271,00€
    10g
    3.696,00€
  • Adenosine 2',3'-cyclic monophosphate

    CAS:
    <p>Adenosine 2',3'-cyclic monophosphate triethylammonium salt (AMP-TEA) is a structural analogue of adenosine. It is a potent inhibitor of protein synthesis by preventing the phosphodiesterase activity of cyclic nucleotide phosphodiesterases and cyclic nucleotide phosphodiesterase. AMP-TEA can be used as a tool to study translation in tissue culture, as well as to examine the effects on protein synthesis and other biochemical reactions that are regulated by cyclic nucleotides. It is also used for the preparation of tissue samples for enzymatic analysis or for radiolabeling experiments.<br>AMP-TEA has an optimum pH of 4.5, but can be used at lower or higher pH values. The optimal temperature range for use is between 0°C and 50°C, with the maximum stability occurring at 37°C.</p>
    Fórmula:C10H12N5O6P
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:329.21 g/mol

    Ref: 3D-NA10355

    2mg
    227,00€
    5mg
    439,00€
    10mg
    699,00€
    20mg
    1.080,00€
    50mg
    2.018,00€
  • 4-Chloro-5-iodo-pyrrolo[2,3-d]pyriMidine-7-carboxylic acid tert-butyl ester

    CAS:
    <p>Focuses is a chemical compound that does not have any known commercial or industrial uses.</p>
    Pureza:Min. 95%

    Ref: 3D-NC44293

    1g
    276,00€
    2g
    410,00€
    5g
    607,00€
    250mg
    135,00€
    500mg
    182,00€
  • 2-Methylamino-N6-methyladenosine

    CAS:
    <p>2-Methylamino-N6-methyladenosine is an activator that can inhibit the replication of DNA, RNA, and protein synthesis. It is a novel monophosphate nucleoside with antiviral and anticancer properties. 2-Methylamino-N6-methyladenosine has been shown to be effective against human cytomegalovirus and murine leukemia virus (MLV) in cell culture. Furthermore, it has been shown to be active against the herpes simplex virus type 1 (HSV1) in mice after oral administration. 2-Methylamino-N6-methyladenosine is a modified deoxyribonucleoside that contains an amino group at the 2' position of the ribose sugar moiety. It also contains an alkyl group at the 6 position of adenine. This modification confers increased stability to the molecule, which prevents degradation by intracellular nucleases.</p>
    Pureza:Min. 95%

    Ref: 3D-NM162983

    2mg
    300,00€
    5mg
    503,00€
    10mg
    482,00€
  • 2'-O-Propargyladenosine

    CAS:
    <p>2'-O-Propargyladenosine is a modified nucleoside that belongs to the group of deoxyribonucleosides. It is an activator of viral DNA polymerases, which causes the synthesis of viral DNA to stop. This compound has antiviral and anticancer activities. 2'-O-Propargyladenosine has been shown to be effective against various human cancer cell lines in vitro and in vivo. It is a synthetic nucleoside with high purity, showing no detectable impurities by HPLC analysis.</p>
    Fórmula:C13H15N5O4
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:305.29 g/mol

    Ref: 3D-NP00748

    5mg
    135,00€
    25mg
    218,00€
  • 7-deaza-dG-CE Phosphoramidite

    CAS:
    <p>7-deaza-dG-CE Phosphoramidite is a monophosphate nucleotide, which is synthesized by modification of the 7-deaza-dG ribonucleoside. It has an antiviral and anticancer activity, and is used as a building block for novel drugs. 7-Deaza-dG-CE phosphoramidite has been shown to inhibit tumor growth and induce apoptosis in Hep2 cells. It also inhibits HIV replication in vitro. The compound is chemically stable and does not react with other biomolecules.</p>
    Fórmula:C44H54N7O7P
    Pureza:Min. 95%
    Peso molecular:823.9 g/mol

    Ref: 3D-WEA76797

    250mg
    1.734,00€
    500mg
    3.169,00€
  • 6-Methyluridine

    CAS:
    <p>Methyluridine is a derivative of uridine that is used in the synthesis of pyrimidine nucleotides. This drug is also an inhibitor of orotidine 5′-monophosphate decarboxylase, which converts orotic acid to uracil. The conformational properties of methyluridine have been studied and found to be similar to those of other purine derivatives, such as adenine and guanine. In addition, methyluridine has been shown to inhibit the growth of typhimurium and increase the production of uracil in human lymphocytes. Methyluridine is metabolized by hydroxylation in liver microsomes, yielding 6-carboxylic acid.</p>
    Fórmula:C10H14N2O6
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:258.23 g/mol

    Ref: 3D-NM08576

    5mg
    213,00€
    10mg
    338,00€
    25mg
    617,00€
    50mg
    950,00€
    100mg
    1.310,00€
  • 5-Iodocytidine 5'-triphosphate sodium salt - 100mM solution

    CAS:
    <p>5-Iodocytidine 5'-triphosphate sodium salt is a novel antiviral agent. It is the sodium salt of 5-iodocytidine 5'-triphosphate and is used to inhibit viral replication. It inhibits RNA synthesis by interfering with the incorporation of deoxyribonucleosides into the growing DNA chain, which blocks DNA synthesis. This inhibition prevents virus production and may be useful in treating cancer.</p>
    Fórmula:C9H15IN3O14P3
    Pureza:Min. 95%
    Peso molecular:609.05 g/mol

    Ref: 3D-NI159413

    1ml
    1.525,00€
    2ml
    2.475,00€
  • 3'-Deoxyadenosine-5'-triphosphate sodium salt - 10mM aqueous solution

    CAS:
    <p>3'-Deoxyadenosine-5'-triphosphate sodium salt is a nucleotide that has been shown to be effective in chemotherapy. It is a substrate for the synthesis of DNA, RNA, and ATP. 3'-Deoxyadenosine-5'-triphosphate sodium salt is also a building block for DNA polymerase, which is an enzyme that synthesizes DNA from a template. It has been shown to have anticancer activity in drug-resistant cells and can be used as an alternative to purine analogs such as 6-mercaptopurine or cladribine. 3'-Deoxyadenosine-5'-triphosphate sodium salt has been shown to inhibit the production of nucleotides by blocking their conversion into triphosphates, which are necessary for DNA replication and repair. This inhibition leads to apoptosis in cells with high levels of nucleotide turnover such as cardiac and myeloid cells. The drug interactions may depend on the</p>
    Fórmula:C10H16N5O12P3
    Pureza:Min. 95%
    Cor e Forma:Colorless Powder
    Peso molecular:491.18 g/mol

    Ref: 3D-ND71670

    1mg
    924,00€
  • 3'-O-Propargyladenosine

    CAS:
    <p>3'-O-Propargyladenosine is a modified nucleoside that has antiviral and anti-inflammatory properties. It is a synthetic compound that is chemically related to adenosine. 3'-O-Propargyladenosine is an activator of the immune system and it inhibits viral DNA synthesis. The compound also has been shown to reduce inflammation in mice by inhibiting the production of prostaglandin E2 (PGE2). 3'-O-Propargyladenosine has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and cytomegalovirus (CMV).</p>
    Fórmula:C13H15N5O4
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:305.29 g/mol

    Ref: 3D-NP05471

    5mg
    135,00€
    25mg
    410,00€