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Nucleosídeos

Nucleosídeos

Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.

Foram encontrados 3567 produtos de "Nucleosídeos"

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  • 5-Bromo-2'-deoxy-4-thiouridine

    CAS:
    <p>5-Bromo-2'-deoxy-4-thiouridine is a high purity, diphosphate nucleoside with novel anticancer activity. It is a potent activator of the transcription factor NF-kappaB and inhibits the proliferation of cancer cells. 5-Bromo-2'-deoxy-4-thiouridine has been shown to be an effective antiviral agent against HIV and hepatitis B virus in vitro. This compound also inhibits the synthesis of DNA and RNA in human cells, which may be due to its ability to inhibit thymidylate synthase. 5-Bromo-2'-deoxy-4-thiouridine is not active against bacterial cells because they lack thymidylate synthase.</p>
    Pureza:Min. 95%

    Ref: 3D-NB63589

    1g
    1.035,00€
    100mg
    218,00€
    250mg
    443,00€
    500mg
    669,00€
  • N6-Acetyl-2'-deoxyadenosine

    CAS:
    <p>N6-Acetyl-2'-deoxyadenosine is an antiviral and anticancer nucleoside. It is a novel modified nucleoside that has been synthesized with a high degree of purity. N6-Acetyl-2'-deoxyadenosine is active against HIV, Hepatitis C, and other viruses, as well as cancer cells. It also inhibits the activity of bacterial DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. N6-Acetyl-2'-deoxyadenosine has a phosphoramidite structure and is synthesized from 2'-deoxyribonucleosides.</p>
    Fórmula:C12H15N5O4
    Pureza:Min. 95%
    Peso molecular:293.28 g/mol

    Ref: 3D-NA57527

    5g
    534,00€
    10g
    823,00€
    25g
    1.491,00€
  • 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-nitro-1H-indole

    CAS:
    <p>Please enquire for more information about 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-nitro-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C13H14N2O5
    Pureza:Min. 95%
    Peso molecular:278.26 g/mol

    Ref: 3D-ND183206

    1g
    738,00€
    2g
    1.324,00€
    5g
    3.079,00€
  • 2'-Deoxyguanosine-[15N5] monohydrate

    CAS:
    <p>2'-Deoxyguanosine-[15N5] monohydrate is a chemical compound that has been shown to have anticancer activity in colorectal adenocarcinoma cells. The high-activity form of this compound is produced by the addition of a 15N isotope, which can be detected using an electrochemical detector. This compound inhibits the enzyme DNA methyltransferase, preventing the addition of methyl groups to DNA and thereby inhibiting cell growth. 2'-Deoxyguanosine-[15N5] monohydrate also has anti-inflammatory properties due to its ability to inhibit IL-2 receptor signaling.</p>
    Fórmula:C10H13N5O4·H2O
    Pureza:Min. 95%
    Cor e Forma:White/Off-White Solid
    Peso molecular:285.26 g/mol

    Ref: 3D-ND170583

    1mg
    929,00€
    2mg
    1.298,00€
    5mg
    2.340,00€
    10mg
    3.467,00€
    25mg
    6.420,00€
  • Wyosine

    CAS:
    <p>Wyosine is a glycosylated protein that is found in the mitochondria of eukaryotic cells. It has been shown to have an acidic pH and to be non-covalently bound to a molecule with a molecular weight of approximately 2,000 Da. Wyosine binds to the wild-type strain of the bacterium Mycobacterium tuberculosis, which may play a role in its biological properties. This molecule also reacts with antibodies and can be used as an antigen for antibody production. Wyosine is structurally similar to x-ray crystal structures and has been observed by X-ray crystallography at atomic resolution.</p>
    Fórmula:C14H17N5O5
    Pureza:Min. 95%
    Peso molecular:335.32 g/mol

    Ref: 3D-NW159496

    5mg
    2.646,00€
    10mg
    4.409,00€
  • 3'-Deoxycytidine-5'-triphosphate

    CAS:
    <p>3'-Deoxycytidine-5'-triphosphate is a modified nucleoside that is the precursor for DNA synthesis. It is an activator of deoxyribonucleoside triphosphates, which are needed in the production of DNA. 3'-Deoxycytidine-5'-triphosphate has been shown to be active against cancer cells and antiviral agents. This chemical also inhibits viral RNA synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. 3'-Deoxycytidine-5'-triphosphate is novel and high purity, with a CAS number 69383-05-7.</p>
    Pureza:Min. 95%
    Peso molecular:467.1 g/mol

    Ref: 3D-ND71668

    50mg
    1.771,00€
    100mg
    2.759,00€
  • 2'-Deoxyinosine-5'-triphosphate sodium

    CAS:
    <p>2'-Deoxyinosine-5'-triphosphate sodium is a nucleoside that is used as an antiviral, anticancer and novel drug. It inhibits viral replication by inhibiting DNA synthesis in the cell. 2'-Deoxyinosine-5'-triphosphate sodium binds to viral RNA polymerase, preventing the enzyme from creating new DNA strands. This prevents the virus from replicating and spreading to other cells in the body. 2'-Deoxyinosine-5'-triphosphate sodium has been shown to inhibit cancer growth by binding to DNA, which prevents it from dividing and creating new cells. This drug also has antiviral activity against HIV and Herpes Simplex Virus Type 1 (HSV1). 2'-Deoxyinosine-5'-triphosphate sodium is typically used as a buffer solution for peptide synthesis or as a chemical intermediate for various organic syntheses.</p>
    Fórmula:C10H15N4O13P3·xNa
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:492.17 g/mol

    Ref: 3D-ND46159

    100mg
    1.518,00€
  • [(2S,6R)-6-{N4-Benzoylcydin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate

    CAS:
    <p>[(2S,6R)-6-{N4-Benzoylcydin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethylphosphoramidochloridate is an antiviral and anticancer nucleoside phosphoramidite. It is synthesized by reacting the purified 6-(N4-benzoylcydin-1-yl) morpholine with dimethyl phosphorochloridate in pyridine at room temperature. This novel monophosphate nucleoside has been shown to be efficacious against human immunodeficiency virus (HIV) and murine leukemia virus (MLV). The antiviral activity of [(2S,6R)-6-(N4-benzoylcydin-1-yl)-4-(tritylmorpholin]-2(1H)-yl]methyl dimethylphosphoramidochloridate is due to its ability</p>
    Fórmula:C37H37ClN5O5P
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:698.15 g/mol

    Ref: 3D-NB58202

    1g
    1.033,00€
    2g
    1.171,00€
    5g
    2.376,00€
    250mg
    468,00€
    500mg
    693,00€
  • 2',3'-Di-O-benzoyl-N6-benzoyl-L-adenosine

    CAS:
    <p>2',3'-Di-O-benzoyl-N6-benzoyl-L-adenosine (DBBA) is a modified nucleoside with anticancer, antiviral, and synthetic properties. It can be used as a building block for the synthesis of DNA, RNA, or other nucleotide analogues. DBBA has shown activity against certain cancer cells and has been found to inhibit the replication of HIV and herpes simplex virus type 1 in cell culture. DBBA is also known as 2',3'-Dibenzoyl-N6-benzoyladenosine.</p>
    Fórmula:C31H25N5O7
    Pureza:Min. 95%
    Peso molecular:579.56 g/mol

    Ref: 3D-ND145163

    1g
    2.286,00€
    2g
    3.386,00€
  • 2-Chloroadenosine 5'-monophosphate triethylamine salt

    CAS:
    <p>2-Chloroadenosine 5'-monophosphate triethylamine salt is a phosphoramidite that has anticancer and antiviral activities. It is synthesized by reacting 2-chloroadenosine with triethylamine. This product has a novel chemical structure and it can be used as an activator for the synthesis of modified DNA, RNA, and other nucleosides. It is also used in the manufacture of deoxyribonucleosides, ribonucleosides, and other nucleotides.</p>
    Fórmula:C10H13ClN5O7P·C12H30N2
    Pureza:Min. 95%
    Peso molecular:584.05 g/mol

    Ref: 3D-NC10383

    1mg
    233,00€
    5mg
    547,00€
    10mg
    806,00€
    25mg
    1.410,00€
    50mg
    2.377,00€
  • 2',3'-Dideoxy-3',5-difluorocytidine

    CAS:
    <p>2',3'-Dideoxy-3',5-difluorocytidine (ddF) is a nucleotide analogue that inhibits the viral polymerase. It binds to the enzyme and prevents it from synthesizing DNA, which is needed for viral replication. ddF has been shown to be effective against different types of cancer cells, including breast and prostate cancers. This drug also has antiviral properties and is used as an antiviral agent in AIDS therapy. ddF may also be used as a precursor in the synthesis of other nucleosides or nucleotides.</p>
    Pureza:Min. 95%

    Ref: 3D-ND144806

    100mg
    10.033,00€
  • 2'-O-Methylguanosine 5'-monophosphate sodium

    CAS:
    <p>2'-O-Methylguanosine 5'-monophosphate sodium is a nucleoside analog that has been shown to inhibit the growth of human cancer cells. It is a modified monophosphate nucleotide, which is synthesized by the chemical modification of guanosine with 2'-O-methylation at the 5' position and phosphorylation at the 3' position. This drug is not active against viruses and may be used as an anticancer agent. 2'-O-Methylguanosine 5'-monophosphate sodium has also been shown to be effective in treating hepatitis B virus infection. The drug may act as an antiviral agent by interfering with viral DNA synthesis, causing viral particles to aggregate, or by inhibiting viral DNA polymerase activity.</p>
    Pureza:Min. 95%

    Ref: 3D-NM182233

    1g
    1.987,00€
  • 2'-Amino-2'-deoxycytidine-5'-triphosphate

    CAS:
    <p>2'-Amino-2'-deoxycytidine-5'-triphosphate is an inhibitor of viral RNA polymerase. It is a nucleoside analogue that mimics the natural substrate for the enzyme, 2'-deoxycytidine-5'-triphosphate. This compound binds to the active site of viral RNA polymerases and blocks their ability to synthesize RNA. The compound has been shown to inhibit the replication of norovirus and HIV in cell culture. 2'-Amino-2'-deoxycytidine-5'-triphosphate binds to metal ions in the active site of the enzyme, which prevents its binding with the template strand and prevents elongation of RNA synthesis.</p>
    Fórmula:C9H17N4O13P3
    Pureza:Min. 95%
    Peso molecular:482.17 g/mol

    Ref: 3D-NA09399

    10mg
    668,00€
    25mg
    1.085,00€
    50mg
    1.627,00€
    100mg
    2.535,00€
  • IDA-dAMP


    <p>An iminodiacetic acid phophoramidite.  This acts as a pyrophosphate mimic so behaves as a leaving group in the enzymatic polymerisation of deoxyribonucleic acids.</p>
    Fórmula:C14H19N6PO9
    Peso molecular:446.31 g/mol

    Ref: 3D-NI02226

    10mg
    2.112,00€
  • Thymidine 3'-monophosphate sodium salt

    CAS:
    <p>Thymidine 3'-monophosphate sodium salt (TMP) is a nucleoside that is involved in the synthesis of DNA. TMP has been shown to have minimal carcinogenic effects on the liver, with no effect on the rate of DNA synthesis or cell proliferation in vivo. It has been shown to be hepatotoxic and genotoxic in animal studies and can cause DNA strand breaks and chromosomal aberrations in liver cells. TMP also causes a specific adduct, crotonaldehyde, which is considered to be an indicator of hepatic injury. The detection method for this adduct uses gas chromatography-mass spectrometry, which identifies the presence of TMP by detecting its unique mass spectrum.</p>
    Fórmula:C10H15N2O8P•xNa
    Pureza:Min. 95%
    Cor e Forma:Powder

    Ref: 3D-NT156795

    1g
    4.697,00€
    50mg
    731,00€
    100mg
    1.065,00€
    250mg
    1.982,00€
    500mg
    3.112,00€
  • 2'-O-tert-Butyldimethylsilyl-N6-(tert-butylphenoxyacetyl)-5'-O-DMT-adenosine 3'-CE phosphoramidite

    CAS:
    <p>2'-O-tert-Butyldimethylsilyl-N6-(tert-butylphenoxyacetyl)-5'-O-DMT-adenosine 3'-CE phosphoramidite is a high purity, diphosphate nucleoside. This is an anticancer drug that inhibits the growth of cancer cells by inhibiting DNA synthesis and RNA synthesis. It is a novel compound that has been shown to be an activator of cellular proliferation in vitro. 2'-O-tert-Butyldimethylsilyl-N6-(tert-butylphenoxyacetyl)-5'-O-DMT-adenosine 3'-CE phosphoramidite is used as a monophosphate nucleoside synthase inhibitor in the treatment of cancer.</p>
    Fórmula:C58H76N7O9PSi
    Pureza:Min. 95%
    Peso molecular:1,074.33 g/mol

    Ref: 3D-PB63472

    1g
    327,00€
    2g
    486,00€
    5g
    1.007,00€
    10g
    1.518,00€
    500mg
    211,00€
  • 2'-O-tert-Butyldimethylsilyl-N4-(tert-butylphenoxyacetyl)-5'-O-DMT-cytidine 3'-CE phosphoramidite

    CAS:
    <p>2'-O-tert-Butyldimethylsilyl-N4-(tert-butylphenoxyacetyl)-5'-O-DMT-cytidine 3'-CE phosphoramidite is a DNA synthesis reagent that is used in the preparation of oligonucleotides, in particular for the synthesis of 2'-deoxyribonucleosides. It has been shown to be an activator and to have anticancer, antiviral, and antimalarial properties. This compound is synthesized by reacting 5'-O-DMT cytidine with 2',3' epoxypropyltrichlorophosphite. The product is purified by silica gel column chromatography and recrystallization from ethanol followed by vacuum drying. CAS No. 149989-66-2</p>
    Fórmula:C57H76N5O10PSi
    Pureza:Min. 95%
    Peso molecular:1,050.3 g/mol

    Ref: 3D-PB63473

    1g
    329,00€
    2g
    478,00€
    5g
    962,00€
    10g
    1.494,00€
    500mg
    208,00€
  • 2'-O-tert-Butyldimethylsilyl-N-(tert-butylphenoxyacetyl)-5'-O-DMT-guanosine 3'-CE phosphoramidite

    CAS:
    <p>2'-O-tert-Butyldimethylsilyl-N-(tert-butylphenoxyacetyl)-5'-O-DMT-guanosine 3'-CE phosphoramidite is a synthetic nucleoside analog. The chemical name for this product is 2'-O-tert-butyldimethylsilyl-N-(tert-butylphenoxyacetyl)-5'-O-dimethoxytritylguanosine 3'-cyanoethylphosphoramidite. The molecular formula is C28H34N2O8PSi, and the molecular weight is 812.59 g/mol. This product has an EC Number of 61317 - CAS Number of 149989 - 68 - 4 and a melting point of 232°C (238°F). This compound can be used in the synthesis of oligonucleotides that are used to bind to RNA and</p>
    Fórmula:C58H76N7O10PSi
    Pureza:Min. 95%
    Peso molecular:1,090.32 g/mol

    Ref: 3D-PB63474

    1g
    329,00€
    2g
    478,00€
    5g
    962,00€
    10g
    1.494,00€
    500mg
    208,00€
  • 2'-Deoxy-5-methyl-isocytidine

    CAS:
    <p>2'-Deoxy-5-methyl-isocytidine is an analog of cytidine that is used in the synthesis of oligodeoxynucleotides. It has shown to be complementary to dsDNA and to inhibit hepatitis B virus replication in cell culture. 2'-Deoxy-5-methyl-isocytidine is synthesized by solid phase chemistry on a polystyrene support with monomers, depyrimidination, and purification by column chromatography. The chemical stability of this compound has been shown by its ability to withstand heating at 100°C for 10 minutes without decomposition.</p>
    Fórmula:C10H15N3O4
    Pureza:Min. 95%
    Peso molecular:241.26 g/mol

    Ref: 3D-ND76392

    1g
    1.952,00€
  • Guanosine-2'(&3')-monophosphate disodium (mixed isomers)

    CAS:
    <p>Guanosine-2'(&amp;3')-monophosphate disodium salt (mixed isomers) is a synthetic nucleoside with antiviral and anticancer properties. It has been shown to activate the transcription of DNA in vitro by binding to the promoter region, resulting in higher levels of RNA synthesis. Guanosine-2'(&amp;3')-monophosphate disodium salt (mixed isomers) has been shown to inhibit the replication of viruses, such as herpes simplex virus type 1 (HSV-1), and it may have potential use in cancer therapy. The drug is also used as a precursor for other antiviral drugs and antibiotics. Guanosine-2'(&amp;3')-monophosphate disodium salt (mixed isomers) is available in high purity, high quality, and at low cost.</p>
    Fórmula:C10H14N5O8P•2Na
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:407.18 g/mol

    Ref: 3D-NG57356

    25mg
    360,00€
    50mg
    475,00€
    100mg
    703,00€
    250mg
    1.163,00€
    500mg
    1.723,00€