Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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6-Azacytidine
CAS:6-Azacytidine is a molecule that contains a hydroxyl group and a glycosidic bond. It has been shown to inhibit the growth of mollicutes, which are non-cellular bacteria. 6-Azacytidine has also been shown to be toxic in animal tissue culture studies. The drug can be eliminated through the urine or bile after being metabolized by the liver. 6-Azacytidine is not active against human cells in cell culture, but it does show some toxicity against human liver cells.Fórmula:C8H12N4O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:244.2 g/mol1-(2'-Deoxy-2'-fluoro-a-L-arabinofuranosyl)-thymine
CAS:1-(2'-Deoxy-2'-fluoro-α-L-arabinofuranosyl)-thymine (commonly abbreviated as L-FMAU) is a nucleoside analog. It contains an α-L-arabinofuranose sugar instead of the natural β-D-deoxyribose found in DNA. A fluorine (F) substitution at the 2'-position enhances stability and resistance to enzymatic degradation. The thymine nucleobase allows it to mimic natural thymidine, potentially incorporating into DNA synthesis pathways. It can be research for its potential antiviral activity.Fórmula:C10H13FN2O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:260.22 g/mol1-(2'-Deoxy-3',5'-di-O-toluoyl-b-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine
CAS:1-(2'-Deoxy-3',5'-di-O-toluoyl-b-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine is a nucleoside derivative that features a modified pyrimidinone (triazine) base attached to a protected deoxyribose sugar. This molecule can be used in research.Fórmula:C24H24N4O6Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:464.48 g/mol6-Amino-3-iodo-4-methoxy-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
CAS:6-Amino-3-iodo-4-methoxy-1-(beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a synthetic nucleoside that has antiviral activity. It is an activator of DNA polymerase and can be used to synthesize DNA and RNA. 6AIOMP binds to the ribonucleotide reductases in cells and inhibits their activity. This prevents the conversion of ribonucleotides into deoxyribonucleotides, which are essential for DNA synthesis.Pureza:Min. 95%5’-O-DMT-2’-b-C-methyladenosine
5’-O-DMT-2’-b-C-methyladenosine is a modified nucleoside with antiviral and anticancer activity. It is an activator of DNA synthesis, and can be used as a precursor for phosphoramidites for the synthesis of oligonucleotides. The 5’-O-DMT group in this compound may be replaced with other activating groups to synthesize different modified nucleosides.
Pureza:Min. 95%3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine
CAS:3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine is a novel synthetic nucleoside that has been shown to have anticancer and antiviral activities. The compound is an activator of the immune system, which may be due to its ability to stimulate the production of interferon and other cytokines. 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine can also inhibit viral DNA polymerases. This nucleoside has been shown to inhibit the growth of leukemia cells in culture by inhibiting ribonucleotide reductase activity.Fórmula:C16H29N3O5SiPureza:Min. 95%Peso molecular:371.51 g/mol3’-deoxy-3’-fluorosangivamycin
CAS:3’-deoxy-3’-fluorosangivamycin is a modified deoxyribonucleoside with antiviral and anticancer properties. It is an activator of DNA polymerase. 3’-deoxy-3’-fluorosangivamycin has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) in the calf thymus DNA system. This drug is also effective against other viruses, such as herpes simplex virus type 2 (HSV-2), cytomegalovirus (CMV), and influenza A virus. 3′-deoxy-3′-fluorosangivamycin binds to viral DNA and inhibits nucleotide incorporation, leading to inhibition of viral RNA synthesis and protein synthesis.Pureza:Min. 95%9-(b-D-Arabinofuranosyl)-8-chloroadenine
CAS:9-(b-D-arabinofuranosyl)-8-chloroadenine is a deoxyribonucleoside that is structurally related to adenosine. It has antiviral properties and has been shown to be active against herpes virus, influenza A virus, and cytomegalovirus. 9-(b-D-Arabinofuranosyl)-8-chloroadenine is an activator of cellular DNA polymerase δ and has been shown to inhibit the replication of HIV in human T lymphocytes. 9-(b-D-Arabinofuranosyl)-8-chloroadenine also inhibits the proliferation of tumor cells and is being investigated as a potential chemotherapeutic agent for cancer treatment.
Pureza:Min. 95%5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine
CAS:5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine is a monophosphate nucleoside that inhibits viral replication by inhibiting the synthesis of both DNA and RNA. This compound is used to treat cancers such as leukemia, lymphoma, and multiple myeloma. It also has antiviral properties that are active against herpes simplex virus (HSV) and human cytomegalovirus (CMV). 5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine is a modified nucleoside with a phosphoramidite group on the 2' position of the ribose sugar.Fórmula:C13H14ClN5O5Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:355.74 g/molPseudothymidine
CAS:Pseudothymidine is the nucleobase analog of thymidine. It is a synthetic substance that has been used in the polymerase chain reactions (PCRs) to form DNA molecules. Pseudothymidine is not naturally found in cells and can be used as a substitute for thymidine during PCR to make more copies of DNA sequences. It has been shown that pseudothymidine can be incorporated into DNA without disrupting the polymerase chain reaction. The thermal denaturation of pseudothymidine is 10 °C lower than that of thymidine, allowing it to be used at higher temperatures with less risk of degradation.Fórmula:C10H14N2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:242.23 g/molBBQ-650-DT CEP
CAS:BBQ-650-DT CEP is an antiviral compound that is a phosphoramidite derivative of cytidine. BBQ-650-DT CEP has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in vitro, and to inhibit tumor cell proliferation in vivo. BBQ-650-DT CEP also inhibits the synthesis of RNA and DNA, which may have anticancer properties. This compound has been shown to be active against leukemia cells, lymphoma cells, and various breast cancer cell lines. It has also been shown to induce apoptosis in leukemia cells.Fórmula:C76H89N12O15PPureza:Min. 95%Peso molecular:1,441.6 g/mol3'-O-Aminoacetoxy-2'-deoxycytidine
Please enquire for more information about 3'-O-Aminoacetoxy-2'-deoxycytidine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C12H18N4O4Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:282.30 g/mol5'-Amino-5'-deoxythymidine
CAS:5'-Amino-5'-deoxythymidine is a nucleoside that is structurally related to thymidine. It has been shown to be a substrate for fatty acid synthase, which is a key enzyme in the synthesis of membrane lipids. 5'-Amino-5'-deoxythymidine has been shown to induce tumorigenesis in mouse bladder carcinoma cells. This compound also does not form stable complexes with DNA duplexes and can inhibit uptake of thymidylate into cells by competitive inhibition. 5'-Amino-5'-deoxythymidine binds to the cell surface and acts as an antibody response modifier.Fórmula:C10H15N3O4Pureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:241.24 g/mol3’-β-Azido-2’,3’-dideoxy-5-fluorouridine
CAS:Please enquire for more information about 3’-beta-Azido-2’,3’-dideoxy-5-fluorouridine including the price, delivery time and more detailed product information at the technical inquiry form on this page
Pureza:Min. 95%5'-O-Tritylthymidine
CAS:5'-O-Tritylthymidine is a nucleoside that is found in human mitochondrial DNA. It is synthesized from uridine by the enzyme thymidylate synthase and can be converted to thymine by the enzyme thymidine phosphorylase. 5'-O-Tritylthymidine has been shown to inhibit cancer cell growth, but its mechanism of action is not clear. It may inhibit xylene production. 5'-O-Tritylthymidine also causes an increase in p53 activity, which may lead to apoptosis of cancer cells.Fórmula:C29H28N2O5Pureza:Min. 95%Peso molecular:484.54 g/molN-Boc-5'-chloro-5'-deoxy-2,3-O-isopropylideneadenosine
N-Boc-5'-chloro-5'-deoxy-2,3-O-isopropylideneadenosine is a novel nucleoside phosphoramidite. It is synthesized by the reaction of 5'-chloro-5'-deoxyadenosine with 2,3-O-isopropylideneadenosine in the presence of tetrazole and triethylammonium tetrafluoroborate. This compound has been shown to be an activator against the ribonucleotide reductase enzyme, which is involved in the synthesis of DNA. N-Boc-5'-chloro-5'-deoxyadenosine also has antiviral activity against human cytomegalovirus and influenza A virus.Pureza:Min. 95%N3-Methyl-2'-O-methyluridine
CAS:2'-O-methyluridine is an antiviral nucleoside that is used as a phosphoramidite in the synthesis of oligonucleotides. It has been shown to inhibit viral replication, and has been found to be effective in treating HIV-1 by inhibiting reverse transcriptase. N3-Methyl-2'-O-methyluridine also inhibits DNA synthesis and cell proliferation, and may be useful for the treatment of cancer. This modified nucleoside has been synthesized from uracil and contains a methyl group at the 3' position. The methyl group prevents 2'-O-methyluridine from being activated by cellular thymidylate synthase, which normally converts deoxyribonucleotides into ribonucleotides. This novel nucleotide has not yet been used in clinical trials but it may provide an alternative to other drugs used for cancer treatments.
Fórmula:C11H16N2O6Pureza:Min. 95 Area-%Cor e Forma:White Off-White PowderPeso molecular:272.25 g/molN4-Benzoyl-2'-deoxy-2'-fluorocytidine 3'-CE phosphoramidite
N4-Benzoyl-2'-deoxy-2'-fluorocytidine 3'-CE phosphoramidite is a novel DNA phosphoramidite monomer that has been modified to include an N4-benzoyl group at the 2'-position of the sugar. It is synthesized from 4,5-diaminopyrimidine, 1,3-bis(2-chloroethyl)carbodiimide hydrochloride (EDC), and 4-(N,N-dimethylamino)benzoic acid. The benzoyl group allows for the incorporation of this monomer into DNA in place of deoxycytidine. This product is designed to be used in oligonucleotide synthesis as an activator.Fórmula:C46H51FN5O8PPureza:Min. 95%Peso molecular:851.9 g/mol3'-O-Aminoacetoxythymidine
Amino functionalised thymidineFórmula:C13H21N4O4Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:297.33 g/mol5'-Azido-5'-deoxyuridine
CAS:5'-Azido-5'-deoxyuridine is a synthetic nucleobase that is used in the synthesis of oligodeoxynucleotides. It has been shown to have an inhibitory effect on tumor cells, which may be due to its ability to interact with guanosine diphosphate (GDP) and prevent the formation of GTP. 5'-Azido-5'-deoxyuridine has also been shown to have an inhibitory effect on Mycobacterium tuberculosis and Mycobacterium avium complex, but does not affect other bacteria. 5'-Azido-5'-deoxyuridine interacts with RNA by binding to the phosphate group and inhibiting the synthesis of proteins and DNA.Pureza:Min. 95%
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