
Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3567 produtos de "Nucleosídeos"
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Riboflavin 5'-adenosine diphosphate disodium salt hydrate
CAS:<p>Riboflavin 5'-adenosine diphosphate disodium salt hydrate is a chemical compound that can be used as a substrate for nitrate reductase in the presence of molecular oxygen. It can be used to identify mollicutes and diagnose radiation-induced lesions. The reaction mechanism involves the conversion of riboflavin 5'-adenosine monophosphate to riboflavin 5'-adenosine diphosphate by an enzyme called nitrate reductase, which is present in the microorganism. This reaction is accompanied by the release of electrons, which are detected by a fluorescence detector. The rate constant for this reaction is <br>k=1.5x10^-4/s at pH 7 and 37 degrees Celsius with an electrochemical detector and k=2.0x10^-3/s at pH 7 and 37 degrees Celsius with a carbonyl oxygens detector. Riboflavin 5'-</p>Fórmula:C27H31N9Na2O15P2·xH2OPureza:(Uv) Min. 95%Cor e Forma:Yellow Orange PowderPeso molecular:829.51 g/mol1-(3'-azido-3'-deoxy-b-D-ribofuranosyl)-5-nitro-2(1H)-pyridinone
CAS:<p>1-(3'-azido-3'-deoxy-b-D-ribofuranosyl)-5-nitro-2(1H)-pyridinone is a nucleoside analog that has antiviral and anticancer activities. It has been shown to be an activator of cellular DNA polymerase γ, which is involved in the DNA chain elongation process during DNA replication. 1-(3'-azido-3'-deoxy-b-D-ribofuranosyl)-5-nitro-2(1H)-pyridinone also inhibits the activity of human T cell leukemia virus type 1 (HTLV1) reverse transcriptase by binding to its active site and preventing the synthesis of viral DNA. This compound has a high quality with a purity > 98% and is not radioactive or toxic.</p>Pureza:Min. 95%Adenosine 5'-diphosphate monosodium salt
CAS:<p>Used for energy storage and in nucleic acid metabolism</p>Fórmula:C10H14N5NaO10P2Pureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:449.18 g/mol2'/3'-(N-Methylanthraniloyl)-adenosine-5'-monophosphate triethylammonium salt
CAS:<p>2'/3'-(N-Methylanthraniloyl)-adenosine-5'-monophosphate triethylammonium salt is an antiviral agent that is based on ribonucleosides. This drug has been shown to be effective against cancer and herpes simplex virus type 1 (HSV-1) and may have potential as a treatment for HIV. It also inhibits the growth of tumors in animal models. 2'/3'-(N-Methylanthraniloyl)-adenosine-5'-monophosphate triethylammonium salt is synthesized by reacting ribonucleosides with N-(2,2,2,-trimethylpropyl)anthranilic acid chloride in the presence of triethylamine. The resulting product can be purified by column chromatography or recrystallization.</p>Fórmula:C18H21N6O8PPureza:Min. 95%Peso molecular:480.37 g/mol1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one
<p>1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is an antiviral agent that belongs to the class of monophosphate deoxyribonucleosides. It is a novel compound that has been shown to be an activator of high purity and quality. 1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is synthesized from modified ribonucleosides and phosphoramidites. The antiviral activity of this drug against DNA viruses (e.g., herpes, adenovirus) and RNA viruses (e.g., influenza virus) has been shown in vitro and in vivo. In addition, 1-(2-C-Methyl-b--D--ribofuranosyl)-5--nitropyridine--2(1H)--</p>Pureza:Min. 95%5'-O-DMT-2'-O-methyl-5-methyluridine
CAS:<p>5'-O-DMT-2'-O-methyl-5-methyluridine is a modified nucleoside that is used in the synthesis of DNA. It is an anticancer drug and antiviral agent. 5'-O-DMT-2'-O-methyl-5-methyluridine has been shown to inhibit the growth of leukemia cells, even when they are resistant to other drugs. It also inhibits certain viruses, such as herpes simplex virus type 1 (HSV1), by preventing viral replication and inhibiting protein synthesis. This nucleoside is synthesized from 5'-O-DMT and 2'-O-methylcytosine.</p>Fórmula:C32H34N2O8Pureza:Min. 95%Cor e Forma:PowderPeso molecular:574.64 g/mol2-Methylthio-N6-isopentenyladenosine
CAS:<p>A nucleoside analogue of adenosine that arises from post-transcriptional modification. In humans, this is mediated by the enzyme CDK5RAP1 in mitochondrial transfer RNA (tRNA) at amino acid 37. Deficiency for this modification, for example due to CDK5RAP1 deficiency, leads to impaired mitochondrial protein synthesis. This has implications for mitochondrial diseases, as well as cancer, type II diabetes and vitiligo. Synthetic ms2i6A can be used to raise monoclonal antibodies against this nucleotide in vivo.</p>Fórmula:C16H23N5O4SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:381.45 g/molTricyclic nucleoside phosphate
CAS:<p>Akt activation inhibitor</p>Fórmula:C13H17N6O7PPureza:Min. 95%Peso molecular:400.28 g/molN4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
CAS:<p>N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is a diploid DNA molecule that is synthesized by the enzyme diploid. The clone was obtained from a yeast strain, and it has been shown to catalyze the conversion of isoprene to isopentenyl diphosphate. The optical spectra of this compound have been characterized in detail, and it has been found to have an absorption maximum at 243 nm. This compound has also been used in the disruption of yeast chromosomes, and its spectrum has been used as a reference for other compounds with similar chemical structures.</p>Fórmula:C47H54N5O9PPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:863.96 g/mol2-Methylmercapto-4-oxo-6-aminopyrimidine monohydrate
CAS:<p>2-Methylmercapto-4-oxo-6-aminopyrimidine monohydrate is a chemical substance that is used as an anticancer and antiviral agent. It has been demonstrated to inhibit the proliferation of tumor cells in vitro and in vivo, and to deplete tumor cell lines of the enzyme ribonucleotide reductase, which is essential for DNA synthesis. The compound also inhibits the synthesis of viral nucleic acid. 2MMAP has a novel chemical structure that includes a methyl group attached to one nitrogen atom. This modification increases its affinity for DNA and RNA molecules by binding to the phosphate groups on these molecules.</p>Fórmula:C5H7N3OS·H2OPureza:Min. 95%Cor e Forma:PowderPeso molecular:175.21 g/molN2-Isobutyryl-2'-deoxy-5'-O-pixylguanosine
<p>N2-Isobutyryl-2'-deoxy-5'-O-pixylguanosine is a modified nucleotide that has been shown to be an activator of the protein kinase C and may have anticancer and antiviral properties. N2-Isobutyryl-2'-deoxy-5'-O-pixylguanosine is a synthetic nucleoside that is structurally similar to ribonucleosides and deoxyribonucleosides, but contains a modified base. The nucleotide is activated by phosphorylation and then undergoes hydrolysis in the cell to form diphosphate. This product has CAS No. 125965-04-3, purity at 99%, and high quality.</p>Fórmula:C33H31N5O6Pureza:Min. 95%Peso molecular:593.64 g/mol3’-Deoxy-3’C-methyl-5-methyluridine
CAS:<p>3’-Deoxy-3’C-methyl-5-methyluridine is a novel and efficient phosphoramidite monophosphate, which can be used in the synthesis of DNA. This product has antiviral activity against HIV and some other viruses. The phosphoramidite is modified with a diphosphate group, which increases the efficiency of DNA synthesis. 3’-Deoxy-3’C-methyl-5-methyluridine is synthesized by modifying 5′ position with a C6 methylaminomethyl group and coupling with the 3′ deoxynucleoside.</p>Pureza:Min. 95%3’-b-C-Methyl-5-methyluridine
CAS:<p>3’-b-C-Methyl-5-methyluridine is a phosphoramidite that is used as an antiviral agent. It is also known as (2’,3’)-O-(2-methoxyethyl) 5'-O-(4,4'-dimethoxytrityl)thymidine or 3’-b-C-Methyluridine. It has been shown to have anticancer properties in vitro and in vivo, and it can be used for the treatment of prostate cancer. 3’-b-C-Methyluridine is synthesized by the reaction of uracil with bis(trimethylsilyl)acetamide followed by reaction with methylamine. The synthesis of this drug was first reported in 1975.</p>Pureza:Min. 95%5'-O-tert-Butyldiphenylsilyl-7-deaza-2'-deoxy-7-iodoadenosine
<p>5'-O-tert-Butyldiphenylsilyl-7-deaza-2'-deoxy-7-iodoadenosine is a novel synthetic nucleoside with antiviral and antitumor activities. It has been shown to inhibit the activity of the HIV virus by preventing DNA replication. 5'-O-tert-Butyldiphenylsilyl-7-deaza-2'-deoxy-7-iodoadenosine also inhibits the synthesis of RNA and proteins, which can lead to cell death. The compound's high purity and quality are ensured by its CAS number.</p>Fórmula:C27H31IN4O3SiPureza:Min. 95 Area-%Cor e Forma:White Off-White PowderPeso molecular:614.55 g/molN4-Benzoyl-2'-deoxy-5'-O-pixylcytidine
CAS:<p>N4-Benzoyl-2'-deoxy-5'-O-pixylcytidine is a novel nucleoside that is structurally related to cytidine. It is synthesized from 2'-deoxycytidine monophosphate and 4-benzoylpixyl chloride. N4-Benzoyl-2'-deoxy-5'-O-pixylcytidine has antiviral, antiangiogenic and anticancer properties, as well as the ability to inhibit the replication of DNA in cells. This compound can be used for synthesis of phosphoramidites, which are used in the production of oligonucleotides.</p>Fórmula:C35H29N3O6Pureza:Min. 95%Peso molecular:587.64 g/molN4-Benzoyl-2'-deoxy-5'-O-tritylcytidine
CAS:<p>N4-Benzoyl-2'-deoxy-5'-O-tritylcytidine is a nucleoside analog that is used as an antiviral agent. It inhibits DNA synthesis by inhibiting the enzyme DNA polymerase, which is essential for the replication of viral and cellular DNA. N4-Benzoyl-2'-deoxy-5'-O-tritylcytidine also has anticancer activity, which may be due to its ability to inhibit ribonucleotide reductase and thereby block the production of RNA.</p>Fórmula:C35H31N3O5Pureza:Min. 95%Peso molecular:573.65 g/mol5-Methoxy-4’-thiouridine
<p>5-Methoxy-4’-thiouridine is a monophosphate nucleoside that is synthesized by the phosphorylation of 5-methoxy-4’-thioguanosine. It has antiviral activity, which is due to its ability to inhibit viral DNA polymerase and prevent the production of viral DNA. 5-Methoxy-4’-thiouridine also inhibits the synthesis of deoxyribonucleosides and ribonucleosides, thereby preventing the formation of RNA and DNA. This agent has been shown to be an anticancer agent that can cause cell death by inhibiting protein synthesis.</p>Pureza:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-DMT-1-methylguanosine 3'-CE phosphoramidite
CAS:<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-1-methylguanosine 3'-CE phosphoramidite is a synthetic, antiviral monophosphate nucleoside. It is an activator that increases the activity of other nucleosides and can be used in DNA synthesis by incorporation into DNA molecules. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-1-methylguanosine 3'-CE phosphoramidite has been shown to be effective against Hepatitis C virus, Human Immunodeficiency Virus 1 (HIV), and Herpes Simplex Virus 1.</p>Fórmula:C47H64N7O8PSiPureza:Min. 95%Cor e Forma:PowderPeso molecular:914.11 g/molCyclopentenyl cytosine 5'-triphosphate sodium salt
<p>Cyclopentenyl cytosine 5'-triphosphate sodium salt is a synthetic, activator diphosphate. It is used as a phosphoramidite in the synthesis of DNA and RNA. Cyclopentenyl cytosine 5'-triphosphate sodium salt has been shown to have anticancer and antiviral properties.</p>Pureza:Min. 95%
