Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3567 produtos de "Nucleosídeos"
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2’-Deoxy-N4-dimethylcytidine
CAS:<p>2’-Deoxy-N4-dimethylcytidine is a synthetic nucleoside analog that is used to inhibit viral replication in the treatment of AIDS and cancer. It is phosphorylated by adenosine kinase to form deoxydimethylcytidine monophosphate (dDMP), which inhibits viral DNA synthesis by inhibiting the activity of reverse transcriptase, an enzyme involved in the production of viral DNA. 2’-Deoxy-N4-dimethylcytidine has also been shown to inhibit cancer cell growth by interrupting mitosis and inducing apoptosis.</p>Pureza:Min. 95%2'-Deoxy-6-thioguanosine-5'-monophosphate
CAS:<p>Azathioprine is a drug that suppresses the immune system and is used to treat autoimmune disorders such as rheumatoid arthritis, lupus erythematosus, and inflammatory bowel disease. It is an immunosuppressant that prevents the formation of antibodies by blocking the enzyme thiopurine S-methyltransferase. Azathioprine is metabolized in the liver to 6-mercaptopurine, which has been shown to cause leukopenia. The genetic polymorphism of this enzyme can lead to differences in the metabolism and toxicity of azathioprine therapy.</p>Fórmula:C10H14N5O6PSPureza:Min. 95%Peso molecular:363.29 g/mol2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium salt
CAS:<p>2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium salt is a nucleoside that can be used as an antiviral or anticancer drug. It is a modified nucleoside, which is synthesized by phosphoramidite chemistry. 2'-O-Methyl-5'-methyluridine 5'-triphosphate triethylammonium salt has been shown to be an activator of DNA polymerase in vitro and in vivo. It also has high purity and high quality.</p>Fórmula:C11H19N2O15P3Pureza:Min. 95%Peso molecular:512.19 g/molRibavirin 5'-triphosphate tetrasodium salt - 10mM aqueous solution
CAS:<p>Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.</p>Fórmula:C8H15N4O14P3·Na4Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:576.1 g/mol3'-O-Methyladenosine
CAS:<p>3'-O-Methyladenosine (3'OMeA) is a monomethylated adenosine that belongs to the group of nucleosides. It has been found to inhibit the activity of adenosine receptors, which are important for the regulation of blood pressure and central nervous system function. 3'OMeA also inhibits virus replication in human lymphocytes. 3'OMeA is synthesized by reaction with methylamine and purification by column chromatography. The molecule is a potential therapeutic target for HIV/AIDS, as it can be used as a specific agonist in order to block viral entry into cells.</p>Fórmula:C11H15N5O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:281.27 g/mol5’-O-DMT-2’-O-methoxyethyl-5-methyluridine
<p>5’-O-DMT-2’-O-methoxyethyl-5-methyluridine is a novel nucleoside analog with anticancer activity. It is a monophosphate of 5'-O-DMT-2'-O-methoxyethyluridine, which has been shown to inhibit the growth of tumor cells by phosphorylation and activation of DNA polymerase β. 5’-O-DMT-2’-O-methoxyethyluridine also inhibits replication of influenza virus in vitro, and has antiviral properties against herpes simplex virus type 1 (HSV1).</p>Pureza:Min. 95%2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite
CAS:<p>2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite is a nucleotide that is used in the synthesis of DNA. It is an organic compound consisting of a molecule with a phosphate group at one end and a ribose sugar at the other. 2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite is synthesized on a solid support by reacting nucleophilic reagents with the ribonucleoside. This drug has antineoplastic effects, inhibiting cancer cell growth by interfering with the production of ribonucleic acid (RNA) and protein synthesis. Hydrolysis of this drug releases fluorouracil, which inhibits thymidylate synthase, preventing the conversion of dUMP to dTMP, and thus blocking DNA synthesis.</p>Fórmula:C39H46FN4O8PPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:748.78 g/mol3’-Azido-3’-deoxy-N6-dimethyladenosine
CAS:<p>3’-Azido-3’-deoxy-N6-dimethyladenosine (3’ADMA) is a modified nucleoside that can be used as an antiviral and anticancer agent. 3’ADMA is synthesized by modifying the phosphoramidite building block with 2,6-diaminohexanoic acid. This compound is also capable of inhibiting viral replication and tumor growth by inducing DNA damage in cells. 3’ADMA has shown to have high purity and quality, and it can be used in the synthesis of ribonucleosides or deoxyribonucleosides.</p>Pureza:Min. 95%N6,N6,2'-O-Trimethyladenosine
CAS:<p>N6,N6,2'-O-Trimethyladenosine is a nucleoside that is found in small quantities in human tissues. It is synthesized by the enzyme polymerase from adenosine and S-adenosyl-L-methionine. N6,N6,2'-O-Trimethyladenosine is structurally similar to guanosine and cytidine and can be modified by nature or synthetic strategies. N6,N6,2'-O-Trimethyladenosine has been shown to have effects on fertility and may be involved in epigenetics as well as tuberculosis. Its role as an epigenetic marker for gene regulation has not been fully determined.</p>Fórmula:C13H19N5O4Pureza:Min. 88 Area-%Cor e Forma:White PowderPeso molecular:309.32 g/mol1-Amino-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine
<p>1-Amino-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine is a novel nucleoside with anticancer and antiviral activity. It is an activator of the immune system, which can stimulate the production of natural killer cells and cytotoxic T lymphocytes. It has been shown to be a potent inhibitor of HIV replication in vitro. 1-Amino-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine was synthesized by phosphoramidite chemistry and it is available at high purity with CAS No.</p>Pureza:Min. 95%6-Mercapto-9-(2'-deoxy-β-D-ribofuranosyl)purine
CAS:<p>6-Mercapto-9-(2'-deoxy-b-D-ribofuranosyl)purine (6MPD) is a purine nucleoside that is used in the preparation of glycosidic bonds. It forms a glycosidic bond with the terminal residue of an oligosaccharide, which leads to the formation of an oligodeoxynucleotide. 6MPD also has binding properties to DNA binding proteins, and it can be used as a growth factor. 6MPD is obtained by reacting 3-chloroperoxybenzoic acid with sodium trifluoroacetate in the presence of mercaptoethanol and sodium hydroxide. This reaction yields 6MPD as a white solid with a melting point of 179°C.</p>Fórmula:C10H12N4O3SPureza:Min. 95%Cor e Forma:PowderPeso molecular:268.29 g/mol5-Ethynyl-2'-O-methyluridine triphosphate
<p>5-Ethynyl-2'-O-methyluridine triphosphate is a novel nucleoside that contains a methyl group at the 5 position of the uracil ring. It is an antiviral agent for use in the treatment of HIV, herpes simplex virus, cytomegalovirus, and influenza virus infections. 5-Ethynyl-2'-O-methyluridine triphosphate is also used as a precursor to synthesize DNA and RNA. This compound has been shown to have anticancer properties against breast cancer cells.</p>Pureza:Min. 95%1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)uracil
CAS:<p>1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)uracil is a synthetic antiviral agent that inhibits the activity of DNA and RNA polymerases. It also has anticancer properties. The compound is an analogue of 2'-deoxycytidine monophosphate (dCMP). This compound binds to the phosphate group of nucleoside triphosphates and prevents their incorporation into DNA or RNA. 1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy) -2′ fluoro -b D arabinofuranosyl) uracil has been shown to inhibit the growth of cancer cells in vitro.</p>Pureza:Min. 95%2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt
<p>2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt is a nucleoside that can be used in the synthesis of DNA and RNA. It is a synthetic, high quality, and novel compound that has been shown to have antiviral, anticancer, and anti-inflammatory properties. This compound has been shown to inhibit the growth of cancer cells by inhibiting the production of proteins vital for cell division. 2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt has also been shown to be an activator of nucleoside phosphorylase and deoxynucleotide kinase, which are enzymes that catalyze the conversion of nucleosides into their corresponding monophosphates.</p>Pureza:Min. 95%5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine
CAS:<p>5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine is a nucleoside analog. It is synthesized by substituting the hydroxyl group of uridine with a fluorine atom and the 2' position of ribose with a 5'-O-acetyl group. This modification prevents the incorporation of this nucleoside into DNA or RNA, making it an effective antiviral and anticancer agent. 5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine has been shown to be highly active against tumor cells but not normal cells in vitro.</p>Fórmula:C11H11N2O5Pureza:Min. 95%Peso molecular:251.22 g/mol2',3'-Dideoxy-5'-O-DMT-uridine
CAS:<p>2',3'-Dideoxy-5'-O-DMT-uridine is a nucleoside for use in research applications</p>Fórmula:C30H30N4O6Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:514.58 g/mol5'-O-DMT-uridine 3'-CE phosphoramidite
CAS:<p>5'-O-DMT-uridine 3'-CE phosphoramidite is a novel, modified and activator nucleoside. It can be used as an antiviral agent or in the synthesis of DNA. 5'-O-DMT-uridine 3'-CE phosphoramidite has been shown to be cytotoxic in vitro to cancer cells.</p>Fórmula:C39H47N4O9PPureza:Min. 95%Peso molecular:746.79 g/mol3'-O-Aminoacetoxy-2'-deoxyadenosine
<p>amino functionalised nucleoside</p>Fórmula:C13H22N6O3Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:310.36 g/mol1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-docosanoyl)-cytosine
<p>1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-docosanoyl)-cytosine is a deoxyribonucleoside monophosphate with antiviral effects. It is a novel nucleotide analogue that contains an azido group and a 2,4,6-trifluorobenzene moiety. The 4′ position of the sugar is modified with an n-docosanoyl group. 1-(4’Azo-2′deoxy-2′fluoro-bDara)ribonucleosides are synthetic nucleotides that can be used to inhibit viral replication by inhibiting DNA polymerase and RNA polymerase.</p>Pureza:Min. 95%Inosine-3',5'-cyclic-monophosphate triethylammonium - 10 mM aqueous solution
<p>Inosine-3',5'-cyclic-monophosphate triethylammonium is a synthetic nucleoside that functions as an activator of the deoxyribonucleotide synthesis. It has antiviral and anticancer properties, and has been shown to have anti-inflammatory activities. Inosine-3',5'-cyclic-monophosphate triethylammonium has been shown to inhibit the growth of cells in culture and induce apoptosis. This is due to its ability to inhibit DNA synthesis by inhibiting the enzyme ribonucleotide reductase.</p>Fórmula:C10H11N4O7P·NC6H15Pureza:Min. 95%Peso molecular:431.38 g/mol
