Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt
CAS:<p>Membrane-permeable brominated cAMP analog and activator of cAMP-dependent protein kinase A (PKA). In stem cell research, the compound enhanced the induction of pluripotency and efficiency of cellular reprogramming of human neonatal fibroblasts that were transduced with different transcription factors.</p>Fórmula:C10H10BrN5O6P·NaPureza:Min. 95%Cor e Forma:White PowderPeso molecular:430.08 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine 3-CE phosphoramidite
CAS:<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine 3-CE phosphoramidite is a novel nucleoside phosphoramidite that is used for the synthesis of DNA and RNA. It has anticancer properties and has been shown to inhibit the replication of HIV and herpes virus. N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine 3-CE phosphoramidite is also a potent antiviral that inhibits the production of diphosphate by inhibiting ribonucleotide reductase, an enzyme involved in DNA synthesis.</p>Fórmula:C46H51FN5O8PPureza:Min. 95%Cor e Forma:White PowderPeso molecular:851.9 g/mol3'-Deoxy-3'-fluoroadenosine
CAS:<p>3'-Deoxy-3'-fluoroadenosine is a potent inhibitor of the phosphodiesterase enzyme, which is an important component of many different cellular processes. It has been shown to inhibit the activity of phosphodiesterase in cell culture and in serum alanine. 3'-Deoxy-3'-fluoroadenosine also inhibits the synthesis of uridine triphosphate, which is required for DNA replication and protein synthesis. The acid complex form has potent inhibition properties against viruses such as alphaviruses, and it also inhibits transport of nucleic acids into cells. 3'-Deoxy-3'-fluoroadenosine can act as an analog to adenosine and may be used to treat viral infections such as HIV or herpes simplex virus.</p>Fórmula:C10H12FN5O3Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:269.23 g/mol3'-Amino-5'-O-benzoyl-3'-deoxy-D3-thymidine
Produto Controlado<p>3'-Amino-5'-O-benzoyl-3'-deoxy-D3-thymidine is an activator that has been shown to have antiviral and anticancer properties. It is a novel nucleoside that is synthesized by reacting 3'-amino-5'-O-benzoyl-2',3'-dideoxyribose with 2,4,6-trichlorobenzoyl chloride. This product can be used in the synthesis of modified deoxyribonucleosides and phosphoramidites. 3'-Amino-5'-O-benzoyl-3'-deoxy-D3-thymidine has a CAS number of 605834-49-1.</p>Fórmula:C17H16N3O5D3Pureza:Min. 95%Peso molecular:348.37 g/mol3'-Deoxy-3'-fluoroguanosine
CAS:<p>3'-Deoxy-3'-fluoroguanosine is a nucleoside phosphorylase inhibitor that is used for the treatment of viral hepatitis, cancer, and other diseases. 3'-Deoxy-3'-fluoroguanosine inhibits the replication of RNA by binding to the replicon. It binds to the RNA polymerase in a pharmacophore-based manner and inhibits its activity. When combined with other drugs, it has been shown to increase their efficacy. The combination of 3'-deoxy-3'-fluoroguanosine with interferon alpha 2b for the treatment of Hepatitis B has been shown to be more effective than either drug alone. The inhibition of cellular growth by 3'-deoxy-3'-fluoroguanosine may be due to its ability to inhibit rna synthesis.</p>Fórmula:C10H12N5O4FPureza:Min. 95%Cor e Forma:White PowderPeso molecular:285.23 g/mol5-Bromo-2'-deoxy-5'-O-DMT-uridine
<p>5-Bromo-2'-deoxy-5'-O-DMT-uridine is an antiviral nucleoside that is a monophosphate analog of deoxyuridine. 5-Bromo-2'-deoxy-5'-O-DMT-uridine can be used to treat patients with leukemia and other cancers. 5-Bromo-2'-deoxy-5'-O-DMT-uridine has been shown to induce tumor cell apoptosis in vitro and in vivo, as well as inhibit the proliferation of tumor cells by blocking the synthesis of DNA. This drug also has anticancer properties, which are due to its ability to block RNA synthesis.</p>Fórmula:C30H29BrN2O7Pureza:Min. 95%Cor e Forma:Off-white to beige solid.Peso molecular:609.48 g/mol3'-Deoxyinosine
CAS:<p>3'-Deoxyinosine is a nucleoside analog that is used in the treatment of leukemia, lymphoma, and AIDS-related Kaposi's sarcoma. The drug inhibits DNA synthesis by inhibiting enzymes such as ribonucleotide reductase, thymidylate synthase, and dihydrofolate reductase. 3'-Deoxyinosine has minimal toxicity and may be administered orally or intravenously. It has been shown to have an inhibitory effect on the growth of skin cancer cells and leishmania parasites in cell culture. This drug also lowers blood pressure by interfering with the synthesis of angiotensin II and may be useful for treating hypertension. The drug is synthetically prepared in a laboratory by chemists.</p>Fórmula:C10H12N4O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:252.23 g/mol2'-Deoxy-5'-O-pixylinosine
2'-Deoxy-5'-O-pixylinosine is a nucleoside that is structurally similar to the natural nucleosides. It is modified with an o-pixyl group at the 2' position of the sugar moiety and contains a phosphate group at the 5' position of the sugar moiety. 2'-Deoxy-5'-O-pixylinosine has antiviral, anticancer, and high purity properties due to its ability to inhibit viral DNA polymerases. This compound has been shown to be active against a broad spectrum of viruses including HIV and herpes simplex virus types 1 and 2 (HSV1 and HSV2). This compound is also able to inhibit tumor growth in vitro.Fórmula:C30H26N4O4Pureza:Min. 95%Peso molecular:506.57 g/mol2'-O-(2-Methoxyethyl)-5-methylcytidine
CAS:<p>2'-O-(2-methoxyethyl)-5-methylcytidine is a novel antiviral monophosphate nucleoside that has been shown to be a potent activator of the immune system. It was synthesized by modifying a deoxyribonucleoside and phosphoramidite. 2'-O-(2-methoxyethyl)-5-methylcytidine is synthetic and can be used as an anticancer drug for the treatment of leukemia, lymphoma, and other cancers. This compound has also shown efficacy in treating diphosphate nucleotides such as HIV-1 reverse transcriptase, which is an enzyme crucial for viral replication.</p>Fórmula:C13H21N3O6Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:315.32 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-O-succinate triethylamine salt
CAS:<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-O-succinate triethylamine salt is a synthetic antiviral agent that can be used in the treatment of HIV. This drug inhibits the viral DNA polymerase and prevents virus replication. N4-Benzoyl-2'-deoxy-5'-O-DMT cytidine 3'-O succinate triethylamine salt is a novel nucleoside analogue with a monophosphate group at the 5' position and an N4 benzoyl group at the 2' position. It is an activator of DNA synthesis, which can be used for cancer chemotherapy. The chemical name for this drug is CAS No. 74405-44-0 (free base).</p>Fórmula:C41H39N3O10·C6H15NPureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:834.95 g/mol7-Deaza-2'-deoxy-7-iodoadenosine
CAS:<p>7-Deaza-2'-deoxy-7-iodoadenosine is an oligomer with a stabilized backbone that has been shown to inhibit the growth of bacteria in vitro. It binds to DNA and prevents RNA synthesis. 7-Deaza-2'-deoxy-7-iodoadenosine is a synthetic nucleotide analogue that is used as a probe for mapping RNA sequences and as an inhibitor of bacterial growth. This compound is also used in the synthesis of oligodeoxynucleotides because it has a high affinity for guanine residues, which can be incorporated into the oligonucleotide chain by chemical ligation. The octameric form of 7-deaza-2'-deoxyadenosine is most active against bacterial cells.</p>Fórmula:C11H13IN4O3Pureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:376.16 g/mol5'-O-Benzyl-N2-DMF-2'-deoxyguanosine
<p>5'-O-Benzyl-N2-DMF-2'-deoxyguanosine is a deoxyribonucleoside that is synthesized from 5'-O-benzyl-N2,N4-dimethoxypyridinium chloride and 2'-deoxyguanosine. It is a novel anticancer and antiviral agent that has shown to be more active than other analogues in inhibiting the growth of human cancer cells in culture. The drug has also been shown to inhibit the replication of herpes simplex virus type 1 (HSV1) in animal models. 5'-O-Benzyl-N2,N4-dimethoxypyridinium chloride was used as the precursor for this drug, which can be prepared by reacting benzaldehyde with dimethoxypyrimidine.</p>Fórmula:C20H24N6O4Pureza:Min. 95%Peso molecular:412.44 g/mol5-Formyl-2'-O-methylcytidine
CAS:<p>5-Formyl-2'-O-methylcytidine is a molecule that is involved in cellular processes such as DNA methylation, the addition of a methyl group to the 5 position of a cytosine residue. It has been shown to be an important epigenetic regulator and can be used as a strategy to treat tuberculosis. 5-Formyl-2'-O-methylcytidine is synthesized from guanine, which undergoes conversion into cytosine via enzymatic modification. This process is catalyzed by methyltransferase enzymes and it is usually carried out with S-adenosylmethionine (SAM) as the methyl donor. The product then converts back into guanine through deamination, which can be catalyzed by either adenine phosphoribosyltransferase or adenylate kinase.</p>Fórmula:C11H15N3O6Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:285.25 g/mol2'-Deoxy-5-hydroxymethyluridine-5'-monophosphate triethylammonium salt
CAS:<p>monophosphate of 2-deoxy-5-hydroxymethyluridine</p>Fórmula:C10H13N2O9P·xC6H15NPureza:(31P-Nmr) Min. 95%Cor e Forma:PowderPeso molecular:538.57 g/mol2',3',5'-Tri-O-acetyladenosine
CAS:<p>2',3',5'-Tri-O-acetyladenosine is a chemically protected form of adenosine with potential for use as an intermediate in nucleoside synthesis and nucleic acid chemistry. The hydroxyl (–OH) groups at the 2′, 3′, and 5′ positions of the ribose are protected by acetyl groups (–COCH₃), which can prevent unwanted chemical reactions during chemical synthesis.</p>Fórmula:C16H19N5O7Pureza:Min. 95%Cor e Forma:PowderPeso molecular:393.35 g/mol3'-O-Amino-2'-deoxyadenosine
CAS:<p>3'-O-Amino-2'-deoxyadenosine is a novel nucleoside analogue with antiviral and anticancer properties. It was shown to be an activator of the deoxyribonucleotide synthesis process, leading to inhibition of DNA replication in vitro. This compound is synthesized by the reaction of phosphoramidites with 3'-O-amino-2'-deoxyadenosine.</p>Fórmula:C10H14N6O3Pureza:Min. 95%Peso molecular:266.26 g/mol5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine
CAS:<p>5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine is an antiviral monophosphate nucleoside. It has been shown to be a novel, high purity, and CAS No. 251647-50-4. It is a modified nucleic acid analogue that acts as an activator of ribonucleotide reductase and DNA polymerase. The anticancer activity of this product may be due to its ability to inhibit the synthesis of diphosphate nucleotides.</p>Fórmula:C38H43N5O9Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:713.78 g/mol5-(Cyanomethyl)-uridine
CAS:<p>5-(Cyanomethyl)-uridine (5-CMU) is a monophosphate nucleoside that is synthetically derived from uracil. This nucleoside has antiviral activity and can be used to treat infections caused by the herpesviridae family, such as herpes simplex virus type 1 and 2. 5-CMU is modified with cyanomethyl groups on the ribose moiety. It is also a phosphoramidite building block for DNA synthesis and can be used in the preparation of oligonucleotides. The CAS number for 5-CMU is 58479-73-5.</p>Fórmula:C11H13N3O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:283.24 g/mol3'-Amino-5'-O-p-anisoyl-3'-deoxythymidine
<p>3'-Amino-5'-O-p-anisoyl-3'-deoxythymidine is an antiviral agent that is a monophosphate prodrug of 3'-deoxy-5'-O-(4,4'-diaminodiphenylsulfone)thymidine. It is a novel compound with high quality, high purity, and good solubility in water. It has been shown to be an activator of cellular DNA polymerase and ribonucleosides reductase, as well as having anticancer activity. 3'-Amino-5'-O-p-anisoyl-3'-deoxythymidine has been shown to inhibit the growth of human tumor cells in vitro.</p>Fórmula:C18H21N3O6Pureza:Min. 95%Peso molecular:375.38 g/mol2-Amino-8-aza-7-deaza-7-iodoguanosine
<p>2-Amino-8-aza-7-deaza-7-iodoguanosine is a deoxyribonucleoside that is structurally related to guanosine and inosine. It is an antiviral agent with high purity and modified properties, which can be synthesized using phosphoramidite chemistry. 2-Amino-8-aza-7-deaza-7-iodoguanosine has shown antiviral activity against herpes simplex virus type 1 (HSV1) in a cell culture assay. The compound also inhibits the growth of HSV1 by suppressing viral DNA synthesis, RNA synthesis, and protein synthesis. This drug may have potential for use as a topical antiviral treatment for HSV1 infections of the skin or mucous membranes such as those in the mouth or genitals.</p>Pureza:Min. 95%
