Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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3,5-Dichloro-4-pyridone-1-acetic acid
CAS:3,5-Dichloro-4-pyridone-1-acetic acid is a chlorinated derivative of 7-aminocephalosporanic acid that is synthesized from hydrochloric acid and chloroacetic anhydride. It is used in the pharmaceutical industry as a reagent to produce medicines such as antibiotics and anti-inflammatory agents. The product yield of this reaction is high, which makes it an excellent choice for industrial use. 3,5-Dichloro-4-pyridone-1-acetic acid also has a low toxicity profile and can be easily degraded by bacteria in the environment.Fórmula:C7H5Cl2NO3Pureza:Min. 95%Peso molecular:222.02 g/mol2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt
CAS:2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt is a prodrug that is converted to fluorouracil in the body. Fluorouracil inhibits the activity of thymidylate synthase and other enzymes involved in DNA synthesis, which are associated with cancer. It is also an inhibitor binding to the enzyme RNA polymerase II, which may contribute to its anti-cancer effects. 2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt has been shown to inhibit the growth of human tumor cells in culture and in animal models. The matrix effect may be responsible for this activity. 2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt can be used as a model system for studying cancer tissues.Fórmula:C9H12FN2O8P·xNaPureza:Min. 85 Area-%Cor e Forma:White Off-White PowderPeso molecular:326.17 g/mol9-(2',3',5'-Tri-O-benzoyl-2'C-methyl-b-D-ribofuranosyl)purine
CAS:9-(2',3',5'-tri-O-benzoyl-2'C-methyl-β-D-ribofuranosyl)purine is a nucleoside that was synthesized and patented in 1993. It is a novel modified nucleoside with antiviral, anticancer, and DNA activating properties. 9-(2',3',5'-tri-O-benzoyl-2'C-methyl-β-D-ribofuranosyl)purine has been shown to inhibit HIV replication by inhibiting the viral reverse transcriptase enzyme. It also inhibits the growth of human cancer cells in culture and has been studied as an anticancer drug. This nucleoside is a substrate for ribonucleotide reductase and phosphoramidite synthase, which convert it into its monophosphate form. The monophosphate form can be converted into the triphosphate form by phosphatases or polymerasesPureza:Min. 95%2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine 3'-CE phosphoramidite is a novel antiviral agent that inhibits the synthesis of DNA, RNA, and proteins. It is synthesized by the reaction of 5-fluoro-2'-deoxyuridine with 2',3' -dideoxyadenosine 5'-O-(4,4'-dimethoxytrityl)-3',5' -cyanoethyl phosphate in an organic solvent. The product is purified by column chromatography and crystallized from ethyl acetate. 2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine 3'-CE phosphoramidite has been shown to be an anticancer agent against breast cancer cells in vitro and in vivo.Fórmula:C40H48FN4O8PPureza:Min. 95%Cor e Forma:PowderPeso molecular:762.82 g/mol5-Chloro-2-pyridinecarboxylic acid methyl ester
CAS:5-Chloro-2-pyridinecarboxylic acid methyl ester is a monophosphate nucleoside that can be used in the synthesis of DNA and RNA. It is also an antiviral, anticancer, and anticoagulant agent. 5-Chloro-2-pyridinecarboxylic acid methyl ester has been shown to inhibit DNA replication and transcription by inhibiting the activity of enzymes involved in these processes. It can be used as a building block for the synthesis of DNA and RNA. The purity of this product is high, with no detectable impurities at levels above 0.1%.Fórmula:C7H6ClNO2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:171.58 g/mol2’,3’,5’-Tri-O-benzoyl-5-difluoromethyluridine
CAS:2’,3’,5’-Tri-O-benzoyl-5-difluoromethyluridine is a novel modified nucleoside. It is a high quality monophosphate that can be used as an activator for DNA synthesis. This compound has shown anticancer activity in various cell lines and has antiviral properties. It can be used as a phosphoramidite for the synthesis of oligonucleotides. 2’,3’,5’-Tri-O-benzoyl-5-difluoromethyluridine is synthesized by using 5'-DMT-2',3',5' -triphosphate as the starting material. The diphosphate is then oxidized to form the corresponding triphosphate (the active form).Fórmula:C31H24F2N2O9Pureza:Min. 95%Peso molecular:606.53 g/mol3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)cytidine
CAS:Used as a protected cytidine nucleoside in RNA synthesis. Similar to its adenosine counterpart, the 1,1,3,3-tetraisopropyl-1,3-disiloxanediyl (TIPDS or TBDPSi2) group serves as a bulky and selectively acid-labile protecting group for the 3' and 5' hydroxyl groups of the cytidine ribonucleoside during RNA oligonucleotide synthesis.Fórmula:C21H39N3O6Si2Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:485.72 g/molUridine-2',3'-cyclic monophosphate sodium salt
CAS:Uridine-2',3'-cyclic monophosphate sodium salt (CAS No. 15718-50-0) is a novel anticancer agent that has been shown to inhibit the growth of cancer cells in vitro and in vivo. It is a nucleoside analog that inhibits the synthesis of DNA by inhibiting ribonucleotide reductase and deoxyribonucleotide reductase, two enzymes involved in the production of DNA. Uridine-2',3'-cyclic monophosphate sodium salt is also an antiviral agent used to treat herpesvirus infections, such as herpes simplex type 1 and 2. This drug binds to viral RNA polymerase, which prevents viral replication by preventing mRNA synthesis.Fórmula:C9H10N2NaO8PPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:328.15 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-thiophosphoramidite
2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-thiophosphoramidite is a novel antiviral agent that inhibits the replication of viruses. It acts by competitively inhibiting the activity of viral DNA polymerase, preventing the addition of nucleotides to the growing DNA strand and thereby halting viral replication. This product is a deoxyribonucleoside monophosphate that is synthesized from an antiviral ribonucleoside monophosphate. 2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-thiophosphoramidite has been shown to have anticancer properties in vitro. It also has immunostimulating effects, which may be due to its ability to activate cells involved in immune responses.Fórmula:C48H53N6O8PS2Pureza:Min. 95%Peso molecular:937.08 g/mol2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-fluorouridine
CAS:2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-fluorouridine is a nucleoside that inhibits the synthesis of RNA by inhibiting the enzyme RNA polymerase. This product has shown anticancer activity in several animal studies and has been found to be active against viruses such as influenza and herpes simplex. 2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-fluorouridine is an extremely potent inhibitor of HIV replication with a much lower cytotoxicity in comparison to other antiviral drugs. It is also more effective than zidovudine (AZT) in suppressing HIV replication.Pureza:Min. 95%9-(2',3',5'-Tri-O-acetyl-β-D-ribofuranosyl)-6-chloropurine
CAS:9-(2',3',5'-Tri-O-acetyl-b-D-ribofuranosyl)-6-chloropurine is an anticancer drug that belongs to the class of nucleosides. It is a modified nucleoside with a 2'-deoxyribose sugar and a 6-chloropurine base. The synthesis of 9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-6-chloropurine can be achieved by phosphoramidite chemistry. Modified nucleosides have been found to have high antiviral and antitumour activities, as well as being promising for the treatment of HIV infections. 9-(2',3',5'-tri-O acetyl b D ribofuranosyl)-6 chloropurine has also been shown to inhibit the replication of RNA in cells infected with HIV, although it has not yet been used in humans.Fórmula:C16H17ClN4O7Pureza:Min. 95%Cor e Forma:Yellow PowderPeso molecular:412.78 g/molRibavirin 5'-diphosphate lithium
CAS:Ribavirin is an antiviral drug that inhibits the production of viral RNA. Ribavirin 5'-diphosphate is formed in the liver through sequential actions of kinases.Fórmula:C8H14N4O11P2•Li2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:418.03 g/molN4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine
CAS:N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is a novel nucleoside that was synthesized by converting the ribonucleoside 5'-O-DMT to its deoxyribonucleoside form. N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is an antiviral and antiproliferative agent that inhibits DNA synthesis. It also has anticancer activity, but does not have any effect on RNA synthesis. This product is available in high quality and high purity with CAS No. 171486-51-4.Fórmula:C41H37N5O7Pureza:Min. 95%Cor e Forma:PowderPeso molecular:711.76 g/mol2',3',5'-Tri-O-benzoyl-2'-C-methylcytidine
CAS:2',3',5'-Tri-O-benzoyl-2'-C-methylcytidine is a modified cytidine analog. Cytidine is a pyrimidine nucleoside, composed of cytosine attached to a ribose sugar via a β-glycosidic bond. The hydroxyl groups on the ribose sugar at the 2′, 3′, and 5′ positions are protected with benzoyl groups which can prevent side reactions during chemical synthesis. A methyl group is also added to the 2′ carbon of the sugar ring.Fórmula:C31H27N3O8Pureza:Min. 95%Cor e Forma:PowderPeso molecular:569.56 g/mol1-(2’,3’,5’-Tri-O-benzyl-4’-thio-b-D-arabinofuranosyl)uracil
CAS:Ribonucleosides are a type of nucleoside that contains ribose sugar in its structure. Ribonucleosides have been synthesized from 1-(2’,3’,5’-tri-O-benzyl-4’-thio-b-D-arabinofuranosyl)uracil using phosphoramidites. These compounds are novel nucleosides and deoxyribonucleosides with the potential to be used as anticancer agents and antiviral drugs. Ribonucleosides can also act as activators for DNA polymerases, which may be useful in the treatment of cell proliferation disorders. They are modified nucleotides that are high purity, high quality and CAS No. 267665-69-0.Pureza:Min. 95%Thymidine-5'-diphosphate-D-viosamine disodium salt
CAS:Thymidine-5'-diphosphate-D-viosamine disodium salt is a nucleoside that has been conjugated to a carrier molecule. This compound is an anomeric, pyranose, and conjugate acid. It has been shown to have antiviral activity in vitro and in vivo against herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and human cytomegalovirus (CMV). Thymidine-5'-diphosphate-D-viosamine disodium salt inhibits the synthesis of viral DNA by inhibiting the incorporation of uracil into the viral DNA strand. This inhibition prevents the production of new viruses by preventing replication.Fórmula:C16H25N3O14P2Na2Pureza:Min. 95 Area-%Cor e Forma:White Off-White PowderPeso molecular:591.31 g/mol3',5'-Di-O-acetyl-2'-deoxy-2'-fluorouridine
CAS:3',5'-Di-O-acetyl-2'-deoxy-2'-fluorouridine is a nucleoside monophosphate with antiviral activity. It is a synthetic nucleoside that has been modified to be resistant to degradation by ribonucleases. 3',5'-Di-O-acetyl-2'-deoxy-2'-fluorouridine inhibits the synthesis of DNA, RNA and protein and is used for treatment of cancer. This drug is not active against other types of viruses such as herpes simplex virus or cytomegalovirus.
Fórmula:C13H15FN2O7Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:330.27 g/mol3'-Amino-2',3'-dideoxy-5'-O-DMT-N2-isobutyrylguanosine
a specifically designed building block for introducing a 3'-amino group into oligonucleotides. The dideoxy sugar ensures the amino group is the primary functionality at the 3' end, while the DMT and isobutyryl protecting groups ensure controlled reactivity during oligonucleotide synthesis and subsequent modification steps.Fórmula:C35H38N6O6Pureza:Min. 95%Peso molecular:638.71 g/mol5’-Azido-5’-deoxy-2’-O,4’-C-methyleneuridine
CAS:5’-Azido-5’-deoxy-2’-O,4’-C-methyleneuridine is a novel modified nucleoside that is phosphorylated to the 5′ position. It can be used as a purine analogue in the synthesis of DNA and RNA. This compound has antiviral activity, which may be due to its ability to inhibit viral DNA polymerase and/or viral RNA polymerase. 5’-Azido-5’-deoxy-2’-O,4’-C methyleneuridine also has anticancer properties by inhibiting DNA synthesis and cell division.Fórmula:C10H11N5O5Pureza:Min. 95%Peso molecular:281.22 g/mol3’-Deoxy-N6,N6-dimethyladenosine
CAS:Please enquire for more information about 3’-Deoxy-N6,N6-dimethyladenosine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePureza:Min. 95%
