Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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2',3'-O-Isopropylidenecytidine
CAS:2',3'-O-Isopropylidenecytidine is a nucleoside for use in research applications
Fórmula:C12H17N3O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:283.28 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-pseudouridine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-5'-O-DMT-pseudouridine 3'-CE phosphoramidite is a novel, high quality, high purity, and deoxyribonucleoside. It is a phosphoramidite that is used in the synthesis of oligodeoxyribonucleotides and has antiviral, anticancer, and anti-inflammatory activities. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-pseudouridine 3'-CE phosphoramidite inhibits the replication of DNA by inhibiting the synthesis of RNA from DNA. This deoxynucleoside also activates nucleases to degrade proteins that are involved in cancer cell proliferation.Fórmula:C45H61N4O9PSiPureza:Min. 95%Cor e Forma:PowderPeso molecular:861.05 g/mol5-(Isopentenylaminomethyl)uridine
CAS:5-(Isopentenylaminomethyl)uridine is a modified uridine nucleoside that is used in biochemical research. It is the precursor to 5-amino-2'-deoxyuridine, which is converted to 5-iodo-2'-deoxyuridine. This modified uridine nucleoside can be used as a linker molecule for DNA and RNA ligation reactions and for analysis of biological samples. 5-(Isopentenylaminomethyl)uridine has been shown to inhibit the expression of genes in eukaryotes and prokaryotes. It also has been shown to inhibit the ribosome by binding to the peptidyl transferase center (PTC).Fórmula:C15H23N3O6Pureza:Min. 95%Peso molecular:341.36 g/mol5-Aza-7-deazaguanosine
CAS:5-Aza-7-deazaguanosine is a nucleoside analogue that has antiviral activity against herpes simplex virus, influenza, and other DNA viruses. 5-Aza-7-deazaguanosine is an analog of guanosine with the addition of a 7-deaza group on the nitrogen atom. This drug inhibits viral replication by inhibiting the polymerase function of the viral NS5B protein, which is essential for DNA synthesis. The structure activity relationship studies have shown that this compound has anti-hepatitis B virus activity, but not against hepatitis C virus. 5-Aza-7-deazaguanosine has been shown to be effective in animal models as well as in humans without any significant toxicity issues.Fórmula:C10H13N5O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:283.24 g/mol4-(b-D-Ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one
CAS:Ribonucleosides, Deoxyribonucleosides and Activator are a group of synthetic compounds that are used in the synthesis of DNA. Ribonucleosides and Deoxyribonucleosides are nucleotides that contain ribose or deoxyribose as the sugar moiety. Activator is an activator for DNA polymerase, which catalyses the formation of a phosphodiester bond between two adjacent 3'-5' phosphate groups on a single strand of DNA. Ribonuclesides, Deoxyribonucleosides and Activator are used in recombinant DNA technology to synthesize DNA molecules containing modified bases. The CAS number for Ribonuclesides, Deoxyribonucleosides and Activator is 59892-40-9.
Fórmula:C10H12N4O5Pureza:Min. 95%Peso molecular:268.23 g/mol5’-ODMT cET-uridine 3’-OCE amidite
CAS:5’-ODMT cET-uridine 3’-OCE amidite is a bicyclic nucleoside that is commonly known as BNA for bicyclic nucleic acid or LNA for locked nucleic acid. It comprises a bridge between the 4' and 2' carbon atoms to lock the ribose ring into a fixed configuration. The BNA or LNA incorporated oligonucleotides are useful to regulate gene expression via antisense mechanisms.Fórmula:C41H49N4O9PPeso molecular:772.82 g/mol2'-Amino-2'-deoxyadenosine-5'-triphosphate sodium salt - aqueous solution
CAS:2'-Amino-2'-deoxyadenosine-5'-triphosphate sodium salt - aqueous solution is a modified ATP analog, where the ribose has a 2'-amino substitution. This compound has potential research applicationsFórmula:C10H17N6O12P3·xNaPureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:506.2 g/molN6-Cyclopentyladenosine
CAS:N6-Cyclopentyladenosine is a nucleoside analog that binds to the kappa-opioid receptor. The physiological effects of this drug are mediated through its interaction with the kappa-opioid receptor, which is found in the central nervous system and mediates many of the effects of morphine. N6-Cyclopentyladenosine has been shown to increase blood flow and heart rate in humans. This drug also inhibits tetrazolium dye uptake by papillary muscle cells, suggesting that it may have cardiotonic effects. N6-Cyclopentyladenosine has been used as an analytical probe for adenosine, which is metabolized by cyclic AMP and cyclic GMP phosphodiesterases into adenosine 3',5'-cyclic monophosphate (cAMP).Fórmula:C15H21N5O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:335.36 g/molCytidine-5-carboxylic acid sodium
CAS:Cytidine-5-carboxylic acid sodium salt is a nucleoside that is used as an activator for the synthesis of phosphoramidites. It is also used in anticancer and antiviral research as a component of DNA. Cytidine-5-carboxylic acid sodium salt is available in high purity, with a monophosphate form and diphosphate forms available.Fórmula:C10H13N3O7•NaPureza:Min. 95%Cor e Forma:PowderPeso molecular:310.21 g/mol2'-Deoxycytidine-5'-diphosphate trisodium salt hydrate
CAS:2'-Deoxycytidine-5'-diphosphate trisodium salt hydrate is a nucleoside that is used as an antiviral agent in the treatment of herpes zoster and varicella zoster. This drug also has anticancer properties, which may be due to its ability to inhibit DNA synthesis. 2'-Deoxycytidine-5'-diphosphate trisodium salt hydrate is a novel nucleotide analogue that has been modified to improve its stability, solubility and bioavailability. It can be used as a starting material for the synthesis of phosphoramidites by reacting with phosphorous pentoxide at elevated temperatures and pH. CAS No. 151151-32-5Fórmula:C9H12N3O10P2·Na3Pureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:453.12 g/mol2'-Deoxyxanthosine
CAS:Produto Controlado2'-Deoxyxanthosine is a chemical compound with biochemical properties that can be used as a pharmaceutical drug. It is a nucleoside analogue that interferes with DNA synthesis. 2'-Deoxyxanthosine inhibits the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides, and prevents the formation of DNA in cells. This drug is also known to have anti-tumor effects, including angiogenesis inhibition and cytostatic activity. The reaction mechanism of 2'-deoxyxanthosine involves nitrous acid, which reacts with the 2' hydroxyl group of xanthosine to form the nitroso intermediate and then reacts with oxygen to produce nitrite and hydrogen peroxide. The final step in this process is the cleavage of xanthosine by nitrite into xanthine and oxalate. This drug has been shown to be reactive at neutral pH conditionsFórmula:C10H12N4O5Pureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:268.23 g/mol2,4-Diamino-6-hydroxypyridine sulphate
CAS:2,4-Diamino-6-hydroxypyridine sulphate is a nucleoside for use in research applicationsFórmula:C4H6N4O•(H2SO4)xPureza:Min. 95%Cor e Forma:PowderPeso molecular:224.2 g/mol5-Carboxymethylaminomethyluridine
CAS:5-Carboxymethylaminomethyluridine is a nucleoside analogue that is used in molecular modeling studies to investigate the role and interactions of uridine in the mitochondrial ribosome. It has been shown to bind to the mitochondrial ribosome, which may be due to hydrogen bonding interactions with adenine. 5-Carboxymethylaminomethyluridine also inhibits protein synthesis at the level of translation by inhibiting group P2 of eukaryotic cytosolic ribosomes. This inhibition results in decreased production of proteins necessary for mitochondrial biogenesis.Fórmula:C12H17N3O8Pureza:Min. 95 Area-%Cor e Forma:White Off-White PowderPeso molecular:331.28 g/mol4-Bromo-3,5-dichloropyridine
CAS:4-Bromo-3,5-dichloropyridine is a reactive intermediate that is used as a reagent in organic synthesis. It has low basicity and reacts with lithium to form the lithium salt. The salt can be deprotonated to form the bromide anion, which is more reactive than the chloride anion. 4-Bromo-3,5-dichloropyridine can also be used for the selective isomerization of ketones and related compounds. Bromine is added to prevent side reactions with oxygen. The intermediates are generated at the site of reaction by using an excess of diisopropylamide over bromination agent.
Fórmula:C5H2BrCl2NPureza:Min. 95%Peso molecular:226.89 g/moldNTP pre-mixes, 10 mM aqueous solution
CAS:dATP, dTTP, dCTP and dGTP pre-mixed in a single vialFórmula:C10H16N5O12P3Pureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:491.18 g/molN2-Acetyl-5'-O-DMT-2'-O-methyl guanosine
CAS:2'-O-Me protected nucleosideFórmula:C34H35N5O8Peso molecular:641.67 g/mol9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)guanine
CAS:9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine is a nucleoside phosphorylase inhibitor that is used to treat inflammatory bowel disease. It has been shown to be effective in treating women with inflammatory bowel disease, and has no significant side effects. 9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine inhibits the bacterial enzyme nucleoside phosphorylase, which is responsible for the conversion of guanosine triphosphate (GTP) to guanosine diphosphate (GDP). This inhibition prevents the synthesis of DNA and RNA by blocking the conversion of GTP and GDP into AMP and GMP. The drug binds to the active site of nucleoside phosphorylase, which is located in the bacterial cytoplasmic membrane. 9-(2'-Deoxy-2'-fluoroFórmula:C10H12FN5O4Pureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:285.24 g/mol2'-O-Methylinosine
CAS:2'-O-Methylinosine is a nucleoside that is structurally related to inosine. It has been shown to induce apoptotic cell death in HIV-infected cells by inhibiting the synthesis of rRNA and by inhibiting the activity of the transcriptase enzyme. 2'-O-Methylinosine has also been shown to inhibit the replication of RNA viruses, such as herpes simplex virus and cytomegalovirus, and it can be used as an experimental model for studying apoptosis. 2'-O-Methylinosine can be synthesized from inosine using a chromatographic method that utilizes hydroxylamine. The chemical structure of this nucleoside is amphipathic, which allows it to bind both DNA and RNA strands.Fórmula:C11H14N4O5Pureza:Min. 99 Area-%Cor e Forma:White PowderPeso molecular:282.25 g/molAdenosine-5’-triphosphate disodium salt trihydrate
CAS:Please enquire for more information about Adenosine-5’-triphosphate disodium salt trihydrate including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C10H14N5O13P3·2Na·3H2OPeso molecular:605.19 g/mol8-Chloro-2'-deoxyadenosine
CAS:8-Chloro-2'-deoxyadenosine is a nucleoside analogue and a disinfectant that inhibits the synthesis of DNA. It has been used to control active viruses and to induce apoptotic cell death in cancer cells. 8-Chloro-2'-deoxyadenosine binds to viral RNA and DNA, preventing viral replication by inhibiting the activity of reverse transcriptase, which is an enzyme that copies the virus's genetic information from RNA into DNA. This drug has also been shown to be effective for the treatment of HIV infection. 8-Chloro-2'-deoxyadenosine disrupts DNA synthesis and cellular metabolism by blocking transcription and protein synthesis.Fórmula:C10H12ClN5O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:285.69 g/mol
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